Oulu Health Care Center

Oulu, Finland

Oulu Health Care Center

Oulu, Finland
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PubMed | Oulu Health Care Center, University of Oulu, Specialist Dental Health Care Unit and University of Tampere
Type: | Journal: Journal of clinical periodontology | Year: 2015

To study the association between periodontitis and serum parathyroid hormone (PTH) and the response of PTH to periodontal therapy in type 1 diabetic patients (T1DM). We also investigated the PTH-1,25(OH)Periodontal health status was recorded in 54 periodontitis patients and 30 periodontally healthy controls (case-control data). Data were also collected from patients with type 1 diabetes mellitus at the baseline (n=76) and after periodontal therapy (intervention data) (n=53).Periodontitis was not associated with serum PTH in the case-control data or at the baseline of the intervention data. A post-therapy increase in serum PTH was found in 61% of the T1DM patients; in patients with moderate or severe periodontitis (n=26) the average increase was 0.6pmol/l (p=0.016) and in patients with no or mild periodontitis (n=27) 0.2pmol/l (p=0.250). In 47% of the T1DM patients, an increase in PTH was associated with an increase in serum 1,25(OH)An association between serum PTH and periodontal infection was found only after periodontal therapy in T1DM patients. This post-treatment response in serum PTH may partly explain the previously reported increase in serum 1,25(OH)

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