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Arkadelphia, AR, United States

Ouachita Baptist University is a private, liberal arts, undergraduate institution located in Arkadelphia, Arkansas, which is about 65 miles southwest of Little Rock. The university's name is taken from the Ouachita River, which forms the eastern campus boundary. It is affiliated with the Arkansas Baptist State Convention. The student body is approximately 45% male and 55% female. Wikipedia.

Hartman J.H.,University of Arkansas for Medical Sciences | Bradley A.M.,Vanderbilt University | Laddusaw R.M.,Texas A&M University | Perry Jr. M.D.,Ouachita Baptist University | Miller G.P.,University of Arkansas for Medical Sciences
Archives of Biochemistry and Biophysics | Year: 2013

CYP2E1 plays a critical role in detoxification and carcinogenic activation of drugs, pollutants, and dietary compounds; however, these metabolic processes can involve poorly characterized cooperative interactions that compromise the ability to understand and predict CYP2E1 metabolism. Herein, we employed an array of ten azoles with an emphasis on pyrazoles to establish the selectivity of catalytic and cooperative CYP2E1 sites through binding and catalytic studies. Spectral binding studies for monocyclic azoles suggested two binding events, while bicyclic azoles suggested one. Pyrazole had moderate affinity toward the CYP2E1 catalytic site that improved when a methyl group was introduced at either position 3 or 4. The presence of methyl groups simultaneously at positions 3 and 5 blocked binding, and a phenyl group at position 3 did not improve binding affinity. In contrast, pyrazole fusion to a benzene or cyclohexane ring greatly increased affinity. The consequences of these binding events on CYP2E1 catalysis were studied through inhibition studies with 4-nitrophenol, a substrate known to bind both sites. Most pyrazoles shared a common mixed cooperative inhibition mechanism in which pyrazole binding rescued CYP2E1 from substrate inhibition. Overall, inhibitor affinities toward the CYP2E1 catalytic site were similar to those reported in binding studies, and the same trend was observed for binding at the cooperative site. Taken together, these studies identified key structural determinants in the affinity and stoichiometry of azole interactions with CYP2E1 and consequences on catalysis that further advance an understanding of the relationship between structure and function for this enzyme. © 2013 Elsevier Inc. All rights reserved. Source

Hartmann P.,Hungarian Academy of Sciences | Hartmann P.,Baylor University | Kovacs A.Z.,Hungarian Academy of Sciences | Douglass A.M.,Ouachita Baptist University | And 3 more authors.
Physical Review Letters | Year: 2014

We report complex plasma experiments, assisted by numerical simulations, providing an alternative qualitative link between the macroscopic response of polycrystalline solid matter to small shearing forces and the possible underlying microscopic processes. In the stationary creep regime we have determined the exponents of the shear rate dependence of the shear stress and defect density, being α=1.15±0.1 and β=2.4±0.4, respectively. We show that the formation and rapid glide motion of dislocation pairs in the lattice are dominant processes. © 2014 American Physical Society. Source

Kolt R.P.,Ouachita Baptist University
National Identities | Year: 2015

Nationalism in Western art music has long been a source of intense controversy. Scholars have struggled to provide an adequate definition of the phenomenon with varying degrees of success; principally because it has always been assumed that the national in music must include purely musical elements in its definition. This assumption has led to often grossly inadequate ideas about how nationalism in music is created by a composer and perceived by a listener. A brief review and reassessment of traditional attempts to define nationalism in music may shed new light on the aesthetic realties of the national in music. © 2014, © 2014 Taylor & Francis. Source

DeWitt T.L.,Ouachita Baptist University | Unruh S.A.,University of Nebraska at Kearney | Seshadri S.,University of Nebraska at Kearney
Journal of Athletic Training | Year: 2012

Context: Medical organizations have recommended that administrators, parents, and community leaders explore every opportunity to make interscholastic athletic programs safe for participation, including employing athletic trainers at practices and competitive events. Objective: To determine the overall level of medical services provided for secondary school-aged athletes at high school athletic events in a rural southern state, to evaluate the employment of athletic trainers in the provision of medical services in secondary schools, and to compare athletic training medical services provided at athletic events among schools of various sizes. Design: Cross-sectional study. Setting: Questionnaires were sent to administrators at 199 secondary schools. Patients or Other Participants: A total of 144 administrators, including interscholastic athletic directors and school principals, from 199 secondary schools participated (72% response rate). Main Outcome Measure(s): Participants completed the Self-Appraisal Checklist for Health Supervision in Scholastic Athletic Programs from the American Academy of Pediatrics, which has been demonstrated to be valid and reliable. The Kruskal-Wallis and Mann-Whitney tests were used to measure differences in groups. Results: We found differences in cumulative scores when measuring between institutional classifications (P≤.05). Cumulative scores for the Event Coverage section of the instrument ranged from 80.5 to 109.6 out of a total possible score of 126. We also found differences in several factors identified in the Event Coverage section (P≤.05). Conclusions: The number of coaching staff certified in cardiopulmonary resuscitation or first aid was minimal. Most schools did not have a plan for providing minimal emergency equipment, ice, or water for visiting teams. We found that 88% (n = 7) of the 8 essential Event Coverage components that the American Academy of Pediatrics deems important were not addressed by schools represented in our study. © by the National Athletic Trainers' Association, Inc. Source

Hajek A.E.,Cornell University | Plymale R.C.,Cornell University | Plymale R.C.,Ouachita Baptist University | Reilly J.R.,Cornell University
Journal of Invertebrate Pathology | Year: 2012

To improve usability of methods for quantifying environmentally persistent entomophthoralean resting spores in soil, we modified and tested two methods using resting spores (azygospores) of the gypsy moth pathogen Entomophaga maimaiga. Both methods were effective for recovering resting spores at concentrations >100 resting spores/g dry soil. While a modification of a method originally described by Weseloh and Andreadis (2002) recovered more resting spores than a modified method based on Percoll density gradients, the ability to estimate true densities from counts was similar for both methods. Regression equations are provided for predicting true resting spore densities from counts, with R2 values for both methods ≥0.90. © 2012 Elsevier Inc. Source

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