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Hyderabad, India

Chari P.R.,Osmania Medical College
Indian Journal of Orthopaedics | Year: 2010

We present a case of simultaneous dorsal perilunate dislocation of both wrists, without a history of fall on outstretched hands. In contrast, it appeared that the mechanism was reverse. His hands were held in radial deviation with wrists in full palmar flexion. The forearms were in neutral position and elbows in mid-flexion. The wrists were suddenly and forcibly pronated. The radiographs of both wrists showed dorsal perilunate dislocation with avulsion fracture of the tip of ulnar styloid process and avulsion fracture of posterior horn of lunate. Radial translation of the carpal bones was also noted. The mechanism is proposed and discussed. Source

Sudha R.,Osmania Medical College
Journal of Indian Academy of Forensic Medicine | Year: 2015

Human death itself is an untoward and unfortunate one for all near and dear ones. Component of unexpectedness specially raises suspicion among relatives, media and community. Deaths in police custody is among the major chunk of such deaths even though low in terms of incidence but having heavy potential of creating major hue and cry. A retrospective study of custodial deaths in various police stations of Andhra Pradesh from 1978 to 1999 was conducted. In spite of diverse difficulties encountered, records of 90 cases could be gathered from various sources like Legal cell of DGP's office, from report of various commission of Inquiry which are available in the library of A.P. Assembly. An attempt was made to review administrative and medico-legal aspects of 90 cases with regards to circumstances of death, various causes of death, nature of death and lapses on the part of the doctors involved in such cases has been made in the present study. Various suggestions are also put forward in the judicial commission to prevent recurrence of such deaths. To the best of our belief and knowledge, such study are very far and few off in bio medical literatures in India. Source

Potharaju N.R.,Osmania Medical College
Indian Journal of Community Medicine | Year: 2012

Background: A performance target (PT) for the incidence rate (IR) of acute encephalitis syndrome (AES) was not defined by the World Health Organization (WHO) due to lack of data. There is no specific treatment for ~90% of the AES cases. Objectives: (1) To determine the IR of AES not having specific treatment (AESn) in two countries, India and Nepal. (2) To suggest the PT. Subjects and Methods: This was a record-based study of the entire population of India and Nepal from 1978 to 2011. The WHO definition was used for inclusion of cases. Cases that had specific treatment were excluded. IR was calculated per 100,000 population per annum. Forecast IR was generated from 2010 to 2013 using time-series analysis. Results: There were 165,461 cases from 1978 to 2011, of which 125,030 cases were from India and 40,431 were from Nepal. The mean IR of India was 0.42 (s 0.24) and that of Nepal was 5.23 (s 3.03). IRs of 2010 and 2011 of India and that of 2011 of Nepal were closer to the mean IR rather than the forecast IR. IR of 2010 of Nepal was closer to the forecast IR. The forecast IR for India for 2012 was 0.49 (0.19-1.06), for 2013 was 0.42 (0.15-0.97) and for Nepal for both 2012 and 2013 was 5.62 (1.53-15.05). Conclusions: IRs were considerably different for India and Nepal. Using the current mean IR as PT for the next year was simple and practical. Using forecasting was complex and, less frequently, useful. Source

Sahay B.K.,Osmania Medical College
Journal of Association of Physicians of India | Year: 2011

In this study, insulin therapy was initiated at onset of disease in patients whose fasting blood glucose was more than 250mg/dl. All enrolled subjects were treated with human premixed insulin (30/70) administered subcutaneously twice daily before breakfast and before dinner. A total of 113 subjects entered the study fulfilling the inclusion criteria. Good glycaemic control was achieved in a few days. The dosage requirement of insulin came down gradually after control was achieved as manifest by hypoglycaemia - leading to withdrawal of insulin. Some of them were managed with diet and exercise alone. Others required small doses of oral antidiabetic agents (OAD). There were no cases of secondary failure to OADs. Ten cases are on average duration of follow-up of 10 years. Two cases are under good control with diet and exercise alone, seven on treatment with oral hypoglycemic agents and one of them requiring insulin to maintain HbA1c below 7%. Thus insulin therapy at onset provides an opportunity to correct all the underlying pathogenic mechanisms i.e. glucotoxicity, lipotoxicity and prevents beta cell apoptosis and suppresses inflammation, leading to beta cell protection. Such timely intervention provides long term benefits, laying the foundation for the concept of beta cell preservation rather that only replacing beta cell function. Hence we propose that all patients with type 2 diabetes should be offered insulin therapy at the onset of their diabetes for a period of 2-4 weeks. © SUPPLEMENT TO JAPI. Source

Lakmala V.,Gandhi Medical College | Inala R.,Osmania Medical College
International Journal of Pharma and Bio Sciences | Year: 2016

The biometrical study of the mandible in human remains will help us in identification of age, sex and race of the individual with available broken pieces of mandible pool with accuracy and clarity. A total of 70 (n=70) adult human mandibles belonging to the Indian population were collected for morphological and morphometric features using ramus breadth, symphysis and condyle height, bigonial breadth, weight, volume and density of the mandible. Based on the maximum and minimum ramus breadth 40 samples could be considered as adult male while, 30 as adult female. Statistical analysis data with mean and SD of various parameters of the mandible viz., ramus breadth, symphysis and condyle height, bigonial breadth, weight, volume and density in male and female were 33.04±0.348 and 27.866±0.668, 31.6±0.327 and 27.6±0.444, 61.125±0.591 and 55.5±0.446, 90.675±0.833 and 81.866±0.919, 61.087±0.712 and 40.433±0.518, 39.025±3.908 and 28.9±0.4022, 1.5628±0.029 and 1.373±0.1255 respectively. Therefore, these results indicated that the average values of all the parameters studied were more in male compared to females. In the present study, there was no statistically significant difference between male and females with respect to different variables however, showed higher values in males compared to females. In conclusion, a large study groups and comprehensive assessment of various parameters related to the mandibles may be required for more definitive and confirmatory results. Source

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