Osijek University Hospital Center

Osijek, Croatia

Osijek University Hospital Center

Osijek, Croatia
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Prlic N.,Osijek University Hospital Center | Kadojic M.,Osijek University Hospital Center
Acta Clinica Croatica | Year: 2012

Te purpose of this prospective study was to determine the quality of life and re-socialization of post-stroke patients in the Osijek-Baranya County during six months. Te study included 161 patients (82 men and 79 women) having sustained their frst ever acute stroke and being treated at University Department of Neurology, Osijek University Hospital Center in Osijek. Te Health Survey SF-36 questionnaire was used for self-evaluation of the patients' physical and mental health. Initial assessment was carried out in the acute phase of the disease and follow-up assessments were carried out 30, 90 and 180 days post-stroke in patient homes. Te mean value of physical health measured by SF was 46.1 on initial measurement, 37.8 on second, 44.3 on third and 53.0 on fourth measurement. Te mean value of mental health was 48.0 on initial measurement, 36.6 on second, 44.0 on third and 48.5 on fourth measurement. Te median of total physical health and mental health on all measurements was higher in men than in women. Comparison of the quality of life areas and the items measured by SF-36 questionnaire according to sex and measurements showed statistically signifcant diferences on all four measurements in women for all items except for social function (p=0.669). In men, statistically signifcant diferences between the measurements were only recorded for the item of physical activity (p=0.013). Stroke signifcantly impairs the quality of life of afected people. Te study showed that the poorest results were recorded 30 days of the onset of symptoms, while recovery was achieved in six months. Patients afected by stroke who stayed with their families considered their physical and mental health better than before stroke.

Calosevic S.,Osijek University Hospital Center | Dinjar K.,Osijek University Hospital Center | Kurbel S.,Osijek Medical Faculty | Steiner R.,Osijek Medical Faculty
General Physiology and Biophysics | Year: 2016

This study is aimed to estimate spatial variability of normal QRS loops trajectories in successive cardiac cycles analyzed in XYZ phase space among 27 young and 27 older subjects, both male and female. Among young subjects, 10 individuals were professional football players, while the remaining 17 were students without regular physical activities. Modified three-axial leads (Frank's lead system) were used continually to record high-resolution ECG (1 kHz sampling rate) at rest during 200 seconds by Biopac Student Lab System. Variability of all the three spherical coordinates of the ventricular electrical vector in five characteristic positions regarding the R peak was analyzed. It was found that although fractal dimensions were not gender-dependent (p > 0.05), the calculated values in all tested five positions were greater in young than in older individuals (p < 0.05). Besides that, among young subjects, several fractal dimensions were greater in athletes than in physically inactive students (p < 0.05). These results suggest that the availability of possible phase space trajectories for QRS vector motion is related to individual physical activity and ageing, leaving less variability to physically inactive or older individuals. Recognizing noninvasive features of heart activity might help early detection of heart problems caused by aging and sedentary life style.

Kristek D.,The Surgical Center | Lovric I.,The Surgical Center | Kristek J.,The Surgical Center | Biljan M.,Osijek University Hospital Center | And 2 more authors.
Collegium Antropologicum | Year: 2010

Proximal femoral fractures, especially in elderly persons with osteoporosis, present a challenge for the traumatologist. While the dynamic hip screw (DHS) became the implant of choice for the treatment of stable fractures, the ideal implant for the treatment of unstable fractures remains an issue. In our experience, Proximal Femoral Nail Antirotation (PFNA) is an excellent device for osteosynthesis as it can be easily inserted, it provides angular and rotational stability and allows early weight bearing on the affected limb. Between February 2007 and August 2009, 76 patents underwent the PFNA fixation for proximal femoral fractures (15 men and 61 women). Forty seven fractures were pertrochanteric, 14 subtrochanteric, 2 pathological and 5 ipsilateral trochanteric and diaphyseal fractures whereas in 8 cases the PFNA was used in reosteosynthesis. The mean age of patients was 73.4 years (range 22-91 years). The fractures were reduced on a traction table and the implant was inserted using minimally invasive technique. Four patients developed superficial postoperative wound infection. No cases of implant breakage have been recorded; there was one cut-out; delayed union was noted in three patients. The majority of patients regained their pre-injury mobility status. The PFNA is an excellent implant for stabilisation of both trochanteric and complex combination fractures as well as an exceptional device for reosteosynthesis. It is easily inserted with few intra- and postoperative complications and allows early weight bearing on the affected limb as well as quicker rehabilitation of patients.

Kurbel B.,University of Zagreb | Golem A.Z.,University of Zagreb | Kurbel S.,Osijek University Hospital Center
Future Oncology | Year: 2015

Adverse effects of targeted drugs on normal tissues can predict the cancer response. Rash correlates with efficacy of erlotinib, cetuximab and gefitinib and onset of arterial hypertension with response to bevacizumab, sunitinib, axitinib and sorafenib, possible examples of 'Black Swan' events, unexpected scientific observations, as described by Karl Popper in 1935. The proposition is that our patients have individual intrinsic variants of cell growth control, important for tumor response and adverse effects on tumor-unrelated tissue. This means that the lack of predictive side effects in healthy tissue is linked with poor results of tumor therapy when tumor resistance is caused by mechanisms that protect all cells of that patient from the targeted drug effects. © 2015 Future Medicine Ltd.

Tomic S.,Osijek University Hospital Center | Vladetic M.,Osijek University Hospital Center | Solic K.,Josip Juraj Strossmayer University of Osijek | Misevic S.,Osijek University Hospital Center | Soldo S.B.,Osijek University Hospital Center
Journal of Clinical Neuroscience | Year: 2013

Recent publications report that a positive applause sign is not only present in patients with neurodegenerative diseases where the subcortical structures are affected but also in patients with cortical dementia. The nature of this sign remains unknown. This study aimed to determine the frequency of the applause sign and its correlation with cognitive impairment in patients with idiopathic Parkinson's disease. The study included 30 non-depressed patients diagnosed with idiopathic Parkinson's disease. Study patients underwent the Unified Parkinson Disease Rating Scale part III, Dementia Rating Scale (DRS), Raven's Colored Progressive Matrices, and Mill Hill Vocabulary tests. Statistical analysis was performed by use of the parametric Student's t-test, nonparametric Mann-Whitney U test and Fisher's exact test, with the level of significance set at p < 0.05. Negative applause sign was recorded in 66.7% and positive applause sign in 33.3% of patients. There were no between-group differences according to age, disease duration, or severity of motor symptoms. The positive applause sign group had significantly lower scores on the initiation/perseveration subscale of the DRS and a significantly higher frequency of scores below the cut-off score on the conceptualization and construction subscales of the DRS. The applause sign appears to be part of a broader dysexecutive syndrome in idiopathic Parkinson's disease. © 2013 Elsevier Ltd. All rights reserved.

PubMed | Osijek University Hospital Center and Josip Juraj Strossmayer University of Osijek
Type: | Journal: Acta neurologica Belgica | Year: 2016

Autonomic dysfunctions are part of a spectrum of non-motor symptoms in Parkinsons disease (PD) patients. The aim of the study was to assess the prevalence of autonomic dysfunctions and their influence on the quality of life (QoL) in PD patients, adjusted for age, sex, disease duration and motor symptoms. Patients were evaluated for motor function (Unified Parkinsons Disease Rating Scale, UPDRS part III), disease stage (Hoehn and Yahr scale, H&Y scale), autonomic dysfunction (Scales for Outcomes in Parkinsons disease, Autonomic, SCOPA-AUT) and QoL (Parkinsons Disease Questionnaire-39, PDQ-39). Urinary, gastrointestinal and sexual autonomic dysfunctions were most frequently reported, while the most severe symptoms were reported for sexual and urinary systems. Age and motor symptoms did not correlate with autonomic dysfunction, while disease duration correlated with cardiovascular dysfunction. There were sex differences on the thermoregulation subscale. All types of autonomic dysfunction influenced QoL, mostly gastrointestinal and thermoregulatory dysfunctions, except for sexual one. Many aspects of QoL (activity of daily living, emotion, cognitive functions, communication and social support) except for stigma and mobility were affected by autonomic dysfunctions. Age, disease duration, sex and motor symptoms were not found to affect global QoL scores, but had detrimental effects on different PDQ-39 dimensions. Autonomic dysfunctions influence QoL in more aspects than motor symptoms, age, disease duration and sex. Patients tend to be more stigmatized with motor than non-motor symptoms.

PubMed | Osijek University Hospital Center and Josip Juraj Strossmayer University of Osijek
Type: Journal Article | Journal: Acta neurologica Belgica | Year: 2016

Cervical dystonia is focal dystonia characterized by involuntary movement of the neck muscle, which leads to abnormal head posture. It can be accompanied with pain and tremor. In this study, we evaluated the presence of depression and anxiety in patients with cervical dystonia and the influence of dystonia symptoms on the quality of life. Psychiatric symptoms were evaluated by use of the Beck Depression Inventory (BDI-II) and Beck Anxiety Inventory. Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) was used to evaluate the cervical dystonia symptoms. Quality of life was assessed by the craniocervical dystonia questionnaire (CDQ-24) and short form 36 health survey (SF-36). Nineteen patients were analyzed. Most of the patients had mild cervical dystonia (mean TWSTRS 23.89). Depression was present in 42.1% and anxiety in 57.9% of the patients. Disability due to cervical dystonia correlated with the occurrence of depression (=0.534) and anxiety (r=0.652). Disability was found to significantly influence the stigma, emotional state, pain, daily activity, social life, physical function, and physical and mental disability. Pain influenced some aspects of body pain, physical function, and physical and mental disability. Being associated with disability and pain, cervical dystonia decreases the quality of life in many aspects. Disability also influenced depression and anxiety, which were present in half of study patients. In addition to follow up for cervical dystonia symptoms, patients with cervical dystonia should also be assessed for psychiatric symptoms on routine clinical check-ups. In addition to botulinum toxin, psychopharmaceuticals should be considered as a treatment option in these patients.

This paper analyzes the aspects of using computer technology in nursing practice. Transfer and managing of data, information and knowledge in nursing is enabled by using modern technology and suitable applications. Cardio applications at the Intensive Care Unit of Department of Cardiac Surgery in Osijek enables nurses/technicians to gain insight into patient personal data, medical history, microbiological findings, interventions that have been made as well as those scheduled in the field of health care, all this by using a few simple connections. Nurses/technicians are those who enter patient data into his/her Electronic Health Record. There are multiple contributions of cardiac system. In comparison with previous paper-based managing of nursing documentation, this program has considerably facilitated and improved nursing practice.

Stenc Bradvica I.,Osijek University Hospital Center | Bradvica M.,Osijek University Hospital Center | Matic S.,Osijek University Hospital Center | Reisz-Majic P.,Osijek University Hospital Center
Neurological Sciences | Year: 2015

The aim of this study was to determine the specificity and sensitivity of the Pelli-Robson and Ishihara diagnostic methods in differing Parkinson’s disease from essential tremor compared to DaTSCAN (dopamine transporter scan) findings. The intention was to investigate whether visual dysfunction appears in the early state of Parkinson’s disease. Therefore, we included patients with the symptomatology of parkinsonism lasting between 6 and 12 months. The study included 164 patients of which 59 (36.0 %) suffered from Parkinson’s disease, 51 (31.1 %) from essential tremor, and 54 (32.9 %) healthy patients which presented the control group. The specificity of Pelli-Robson test in confirming Parkinson’s disease was 53 % and the sensitivity 81.4 %. The specificity of Ishihara test in confirming Parkinson’s disease was 88.2 %, and sensitivity 55.9 %. We found that the colour and contrast dysfunction are present as the earliest symptoms of Parkinson’s disease. In this study the Pelli-Robson test is highly sensitive and the Ishihara tables are highly specific in the differential diagnosis between Parkinson’s disease and essential tremor, but neither of these methods fulfils the criteria for the validity of a test. We suggest performing both of these methods to evaluate which patients are indicated for DaTSCAN. © 2014, Springer-Verlag Italia.

PubMed | Osijek University Hospital Center
Type: Journal Article | Journal: Acta dermatovenerologica Croatica : ADC | Year: 2016

Syringomas are benign tumors of adnexal origin, and eruptive syringoma is an extremely rare subtype. In this paper, we present a case of a unusual occurrence of eruptive syringoma in 66-year old woman that includes clinical and pathohistological findings and the review of the clinical picture, diagnosis, and treatment options.

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