Osaka, Japan
Osaka, Japan

Osaka University , or Handai , is a national university located in Osaka, Japan. It is the sixth oldest university in Japan as the Osaka Prefectural Medical College, and one of Japan's National Seven Universities. Numerous prominent scientists have worked at Osaka University such as the Nobel Laureate in Physics Hideki Yukawa. Wikipedia.

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Patent
Menicon Co. and Osaka University | Date: 2017-05-17

It is an object of the present invention to provide a visibility-ensuring material which is capable of ensuring a surgical field for a predetermined time period, which does not inhibit the transmission of light, and which is capable of ensuring the visibility with which even delicate operations can be satisfactorily performed. A visibility-ensuring material of the present invention includes a gel-like viscoelastic body and has a storage elastic modulus during use of from 40 Pa to 700 Pa. A discharge device for a visibility-ensuring material of the present invention includes: a syringe; and at least one kind selected from the group consisting of a mesh filter, a needle, and an application nozzle.


Patent
Osaka University | Date: 2017-05-17

A measuring device (1) includes a first signal generation section (3) and a first removal section (5). The first signal generation section (3) generates a first source signal (x1(t)) including a fundamental and a plurality of harmonics based on a first physical quantity (p1) and a second physical quantity (p2). The first removal section (5) removes some or all of the harmonics from the first source signal (x1(t)). The first source signal (x1(t)) is a periodic signal, and one period of the first source signal (x1(t)) includes a first signal (p1), a second signal (p2), and a reference signal (pr). The first signal (p1) has a first duration (w1) and indicates the first physical quantity (p1). The second signal (p2) has a second duration (w2) and indicates the second physical quantity (p2). The reference signal (pr) has a third duration (w3) and indicates the reference physical quantity (pr).


Patent
Japan Advanced Telecommunications Research Institute International and Osaka University | Date: 2017-04-05

[Object] To provide a compact, high-output actuator device allowing force control. [Solution] An actuator device 1000 includes an electromagnetic coil member 110 provided over a prescribed width on an outer circumference of a cylinder 100, and a movable element 200 slidable as a piston in the cylinder 100. The movable element 200 has a magnetic member 202, and is moved relatively by excitation of the electromagnetic coil member 110. Fluid is supplied to first and second chambers 106a and 106b such that when the movable element 200 is to be moved relatively, the movable element 200 is driven in the same direction.


Provided is a mutant protein obtained by mutating a specific amino acid residue of HMGR, a rate-limiting enzyme of isoprene monomer biosynthesis in the polyisoprenoid biosynthesis pathway. The present invention relates to a mutant protein, wherein at least one amino acid residue selected from the group consisting of amino acid residues at positions 91, 225, 257, 287, 339, 411, 470, 509 and 574 of the Arabidopsis thaliana 3-hydroxy-3-methylglutaryl CoA reductase shown by SEQ ID NO:1 and amino acid residues at positions corresponding to the foregoing in 3-hydroxy-3-methylglutaryl CoA reductase is deleted or replaced with another amino acid residue.


A method includes: generating a peroxide radical on a dielectric substrate surface by treating the dielectric substrate surface with atmospheric pressure plasma using a rare gas; fixing a functional group forming a coordinate bond with a silver ion, by reacting a grafting agent; and applying a silver-containing composition to the substrate surface, followed by heating and curing the silver-containing composition, to thereby form a silver thin film layer, the silver-containing composition containing a silver compound (A) represented by Formula (1) and an amine compound (B) represented by Formula (2), the silver compound (A) being contained in an amount of 10 to 50% by mass, the amine compound (B) being contained in an amount of 50 to 90% by mass, relative to a total amount of 100% by mass of the silver compound (A) and the amine compound (B). The method enables to form a metal film having high adhesiveness even on the surface of a fluorine resin, which is suitable as a dielectric substrate due to its property of avoidance of delay in signal transmission speed or increase in power consumption, but has extremely low adhesiveness. [C. 1]^(1): a hydrogen atom, -(CY_(2))a-CH_(a), or -((CH_(2))b-O-CHZ)c-CH_(3); R^(2): -(CY_(2))d-CH_(3) or -((CH_(2))e-O-CHZ)f-CH_(3); Y: a hydrogen atom or -(CH_(2))g-CH_(3); Z: a hydrogen atom or -(CH_(2))h-CH_(3); a: an integer of 0 to 8; b: an integer of 1 to 4; c: an integer of 1 to 3; d: an integer of 1 to 8; e: an integer of 1 to 4; f: an integer of 1 to 3; g: an integer of 1 to 3; h: an integer of 1 or 2)


Patent
AnGes MG Inc., Osaka University and DS Pharma Animal Health Co. | Date: 2017-09-27

The present invention provides a combination preparation for inducing a specific immune response to an antigenic peptide, which contains(I) the antigenic peptide, and(II) an expression vector encoding a chimeric hepatitis B virus core antigen polypeptide, into which the antigenic peptide has been inserted or added, wherein said antigenic peptide is inserted in a region of amino acid residues 74 - 87 or 130 - 138 of the hepatitis B virus core antigen polypeptide, or added to the N-terminal or C-terminal of the hepatitis B virus core antigen polypeptide, whereinthe antigenic peptide of (I) and the expression vector of (II) are substantially simultaneously administered to a subject.


Patent
Terumo Kabushiki Kaisha and Osaka University | Date: 2017-09-20

Provided is a sheet-shaped cell culture that includes myocardial cells derived from pluripotent stem cells and has excellent functional properties. A sheet-shaped cell culture obtained by culturing a cell population that includes myocardial cells derived from pluripotent stem cells, wherein the proportion of the number of the myocardial cells derived from pluripotent stem cells to the total number of cells in the cell population is 50% to 70%; a method of producing the sheet-shaped cell culture; a composition including the sheet-shaped cell culture; and a method of treating a disease using the sheet-shaped cell culture or the composition.


Provided is a cell population comprising differentiated cells obtainable by inducing differentiation of pluripotent stem cells, wherein the content ratio of undifferentiated pluripotent stem cells is 0.2% or less.


Patent
Osaka University and JMC Corporation | Date: 2017-09-27

A catheter simulator (10) of the invention has a container (20) filled with a liquid; an elastic heart model (30) installed in a floating state in the liquid with which the container (20) is filled; and a pump (50) connected to the heart model (30). The pump (50) is connected to an apex section of the heart model and produces a pulsatile flow from the apex section toward an aorta. Coronary arteries (33) provided on the surface of a main body (30A) of the heart model (30), pulsate together with the main body as a result of the pulsatile flow flowing from the pump (50).


Patent
Takashima Sangyo Co. and Osaka University | Date: 2017-09-20

A training device to be inserted and placed inside a three-dimensional model of a biological organ manufactured for training, which is capable of reducing the cost of training in which the training device is inserted and placed inside the three-dimensional model, is provided. A stent is formed of a shape-memory alloy and is to be inserted and placed inside a three-dimensional model of a biological organ manufactured for training, under a state in which the stent is mounted on a balloon of a balloon catheter. The stent is expandable under a room temperature environment. When heated to a predetermined temperature higher than room temperature, the stent is contracted until an inner diameter of the stent becomes smaller than an outer diameter of the balloon in a contracted state, and returns to an original shape thereof.

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