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Tsugawa N.,Osaka Shoin Womens University
Clinical calcium | Year: 2015

Vitamin D insufficiency is one of the risk factors of osteoporosis. To know the vitamin D intake for the prevention of bone loss and fracture, it is necessary to evaluate the appropriate serum 25-hydroxyvitamin D (25-D) concentration for bone health, and the vitamin D intake to maintain its concentration. Although vitamin D intake 15 and 20 μg/d have been set as RDA (Recommended Dietary Allowance) in USA/Canada DRIs (Dietary reference intakes), 5.5 μg/d has been set as AI (adequate intake) in Japanese DRIs (2015). While reference values in Japan and USA/Canada were quite different, both DRIs are common in that it aim to maintain the serum 25-D concentration to more than 50 nmol/L. In the present review, vitamin D intakes and bone health, vitamin D status in Japanese people, DRIs for vitamin D and improvement of vitamin D insufficiency are reviewed.

Kobayashi M.,Osaka Shoin Womens University
Journal of the Japan Research Association for Textile End-Uses | Year: 2011

The WMS (Washing Mechanical Action Scale) method developed by Japan Textile Evaluation ology Council is a new way to determine the washing mechanical action by using a printed cotton test cloth. In this study, the basic properties of the WMS test cloth were investigated comparing with the modified MA test cloth by using a Terg-OTometer test washing machine. The results were as follows: 1. The WMS test cloth has the ability to sense the lower mechanical action as compared with the conventional MA test cloth. 2. The WMS value has little influence in existence of the detergent or its type until 30 min. However, it is under the influence of the existence for long washing time such as 60 min. 3. In the range of low (40 °C) to middle (60 °C) temperature, it exercised a little influence on the WMS value. Though, the value would be overestimated at the higher temperature such as 80 °C. Therefore, the WMS method is a practical way to evaluate the washing mechanical action under the general washing condition. © 2011 Jpn.Res.Assn.Text.End-Uses.

Fujimoto J.,Osaka Shoin Womens University | Morooka H.,Kyoto Womens University
Journal of the Japan Research Association for Textile End-Uses | Year: 2016

With the purpose being to efficiently create the reproduction of clothing as historical materials, an image analysis was conducted with a large three-dimensional measurement instrument (BLS) by means of laser light for clothing with a large billowing due to easing-in, and an attempt was made to grasp this objectively and quantitatively with the silhouette of the clothing as the volume value, and were reported in the previous paper. However, BLS is a large-scale equipment and that cannot measure clothes of dark color, in this study, the reproducibility and effectiveness of silhouette measurements using a small hand-held three-dimensional scanner (HS) with a pattern light were investigated through a comparison with the data obtained by BLS. For the torso measurements, the rate of change of the HS measurement values was seen to have a good reproducibility of approximately 1%. In the measurement by HS, it can be seen that the unevenness and marks that serve as the clues for the alignment of the scan data are needed, and it was proposed attaching thread marks that gives due consideration to not leaving any traces on the clothing and that does not alter the shape of the silhouette be used on the cloth. A high degree of congruence was observed between Hm, the volume value measured with HS attaching thread marks, and B, the volume value measured with BLS. © 2016 Jpn. Res. Assn. Text. End-Uses.

Kodama M.,Nissay Hospital | Komura H.,Osaka Shoin Womens University | Kodama T.,Osaka University | Nishio Y.,Osaka Police Hospital | Kimura T.,Osaka University
Endocrine Journal | Year: 2012

Patients with Turner syndrome (TS) almost develop osteoporosis, resulting from chromosomal deficiency and estrogen deficiency by gonadal dysgenesis. The aim of this study was to assess bone mineral density (BMD) during continuous estrogen therapy in young TS patients by measuring lumbar spine BMD of 67 TS patients using dual-energy X-ray absorptiometry. Twenty-seven patients who were treated with adult-doses of estrogen prior to the first evaluation, exhibited a significantly higher initial BMD than 30 patients treated with low-dose estrogen therapy and 10 patients without estrogen therapy (0.808 g/cm 2, 0.714 g/cm 2, and 0.664 g/cm 2, respectively). During continuous adult-dose estrogen therapy, BMD significantly increased in each group (maximum BMD during the study, 0.842 g/cm 2, 0.790 g/cm 2, and 0.724 g/cm 2, respectively). Initial and maximum BMD showed significant negative correlation with the age at which adultdose estrogen therapy was initiated (r = -0.57 and -0.45, respectively). Among the patients not treated with adult-dose estrogen therapy prior to the first evaluation, the annual increase in the rate and amount of BMD was significantly higher when adult-dose estrogen therapy was initiated before age 18 (rate, 4.4% before age 18 vs. 3.1% after age 18; amount, 0.03 g/cm 2 before age 18 vs. 0.02 g/cm 2 after age 18). In summary, estrogen therapy increased BMD in young TS patients and might be more effective if initiated by age 18. © The Japan Endocrine Society.

Kawabata Y.,Osaka Shoin Womens University | Kimura K.,Japan National Agriculture and Food Research Organization | Funane K.,Japan National Agriculture and Food Research Organization
Applied Microbiology and Biotechnology | Year: 2012

A cycloisomaltooligosaccharide (CI; cyclodextran) production system was developed using a Bacillus subtilis expression system for the cycloisomaltooligosaccharide glucanotransferase (CITase) gene. The CITase gene of Bacillus circulans T-3040, along with the α-amylase promoter (PamyQ) and amyQ signal sequence of Bacillus amyloliquefaciens, was cloned into the Bacillus expression vector pUB110 and subsequently expressed in B. subtilis strain 168 and its alkaline (aprE) and neutral (nprE) protease-deficient strains. The recombinant CITase produced by the protease-deficient strains reached 1 U/mL in the culture supernatant within 48 h of cultivation, which was approximately 7.5 times more than that produced by the industrial CITase-producing strain B. circulans G22-10 derived from B. circulans T-3040. When aprE- and nprE-deficient B. subtilis 168 harboring the CITase gene was cultured with 10% dextran 40 for 48 h, 17% of the dextran in the culture was converted to CIs (CI-7 to CI-12), which was approximately three times more than that converted by B. circulans G22-10 under the same dextran concentration. The B. subtilis host-vector system enabled us to produce CIs by direct fermentation of dextran along with high CITase production, which was not possible in B. circulans G22-10 due to growth inhibition by dextran at high concentrations and limited production of CITase. © 2011 Springer-Verlag.

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