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Portland, OR, United States

Oregon Health & Science University is a public university in Oregon with a main campus, including two hospitals, in Portland. It was formed in 1974 as the University of Oregon Health science Center, combining state dentistry, medicine, and nursing programs into a single center Wikipedia.

Sack R.L.,Oregon Health And Science University
New England Journal of Medicine | Year: 2010

A 55-year-old physician is planning a trip from Los Angeles to London to attend a scientific conference. His previous trip to Europe was complicated by sleepiness during meetings and difficulty falling asleep and remaining asleep at night. He wants to know what he can do to avoid jet lag. What would you advise? Copyright © 2010 Massachusetts Medical Society. Source

Hanahan D.,Ecole Polytechnique Federale de Lausanne | Coussens L.,Oregon Health And Science University
Cancer Cell | Year: 2012

Mutationally corrupted cancer (stem) cells are the driving force of tumor development and progression. Yet, these transformed cells cannot do it alone. Assemblages of ostensibly normal tissue and bone marrow-derived (stromal) cells are recruited to constitute tumorigenic microenvironments. Most of the hallmarks of cancer are enabled and sustained to varying degrees through contributions from repertoires of stromal cell types and distinctive subcell types. Their contributory functions to hallmark capabilities are increasingly well understood, as are the reciprocal communications with neoplastic cancer cells that mediate their recruitment, activation, programming, and persistence. This enhanced understanding presents interesting new targets for anticancer therapy. © 2012 Elsevier Inc. Source

Dana-Farber Cancer Institute and Oregon Health And Science University | Date: 2014-10-21

Methods and compositions for the diagnosis of cancer susceptibilities, defective DNA repair mechanisms and treatments thereof are provided. Among sequences provided here, the FANCD2 gene has been identified, and probes and primers are provided for screening patients in genetic-based tests and for diagnosing Fanconi Anemia and cancer. The FANCD2 gene can be targeted in vivo for preparing experimental mouse models for use in screening new therapeutic agents for treating conditions involving defective DNA repair. The FANCD2 polypeptide has been sequenced and has been shown to exist in two isoforms identified as FANCD2-S and the monoubiquinated FANCD-L form. Antibodies including polyclonal and monoclonal antibodies have been prepared that distinguish the two isoforms and have been used in diagnostic tests to determine whether a subject has an intact Fanconi Anemia/BRCA pathway.

Oregon Health And Science University | Date: 2014-11-13

Disclosed are methods of detecting and isolating CD4

Oregon Health And Science University | Date: 2014-01-14

Portable fire drill training apparatuses which mimic an actual building install of a fire alarm system for training in localized areas are disclosed. In one example approach, a portable fire drill training apparatus is described which lacks any heat, smoke, or fire detectors and comprises an enclosure, a fire alarm notification appliance mounted on the enclosure, and a manual fire alarm activation device with an actuation element, where the manual fire alarm activation device is mounted on the enclosure and is configured to activate the fire alarm notification appliance in response to a user engaging the actuation element.

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