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Chandigarh, India

Bhandari S.,Oral Health science Center | Bakshi S.,Chitkara University
Indian Journal of Dental Research | Year: 2013

Spacing in dentition negatively interferes with harmony of the smile. A lot of literature has been devoted to prosthetic closure of such space(s) in the dentition; however, the only option for maintaining space(s) in tooth-supported fixed dental prosthesis (FDP) is with the aid of loop connectors. Eleven patients (seven males and four females) with mean age of 45.18 years (range 22-70 years), previously treated with porcelain fused to metal full coverage restorations joined with loop connectors, were evaluated clinically to assess the clinical status and longevity of treatment provided. All the patients were asked to fill a simple close-ended questionnaire to provide their perspective on the limitations and outcome of the treatment and rate their satisfaction level on the scale of 1-10. The cumulative survival of the FDPs with the aid of loop connectors was 90.9%. There was no reported esthetic failure and, at the time of responding to the questionnaire, none of the patients had active complaint with respect to the prosthesis and all but one of the patients were satisfied with the treatment provided. Clinical survivability and the patient feedback suggests that customized designing of loop connectors for each patient is an excellent treatment modality to successfully maintain excessive (single/generalized) spacing between teeth and effectively splint pathologically migrated and mobile teeth. The reported problems with this treatment option are all transient in nature.

Jena A.K.,Oral Health science Center
The Angle orthodontist | Year: 2011

To test the hypothesis that there is no difference in hyoid bone position among subjects with different vertical jaw dysplasias. Seventy-one North Indian adult male and female subjects in the age range of 15 to 25 years were selected for the study. Based on the vertical growth pattern of the face, subjects were divided into Group I (n = 24; subjects in whom both Frankfort mandibular plane angle [FMA] and basal plane angle measured 20 to 25 degrees), Group II (n = 17; subjects in whom both FMA and basal plane angle measured <15 degrees), and Group III (n = 30; subjects in whom both FMA and basal plane angle measured >30 degrees). Lateral cephalograms with the mandible in rest position were traced and analyzed manually for evaluation of hyoid bone position. The anteroposterior position of the hyoid bone was significantly forward in subjects with short face syndrome compared with normal subjects (P < .05) and subjects with long face syndrome (P < .001). The vertical position of the hyoid bone was comparable among subjects with different vertical jaw dysplasias. The axial inclination of the hyoid bone was more oblique in subjects with long face syndrome than in those with short face syndrome (P < .01). The anteroposterior position of the hyoid bone was more forward in subjects with short face syndrome. The vertical position of the hyoid bone was comparable among subjects with different vertical jaw dysplasias. The axial inclination of the hyoid bone closely followed the axial inclination of the mandible.

Kumar A.,PGIMER | Bhattacharyya S.,PGIMER | Rattan V.,Oral Health science Center
Cell and Tissue Banking | Year: 2015

Human dental pulp stem cells (hDPSCs) hold great promise as a source of adult stem cells for utilization in regenerative medicine. Successful storage and post thaw recovery of DPSCs without loss of function is a key issue for future clinical application. Most of the cryopreservation methods use controlled rate freezing and vapor phase nitrogen to store stem cells. But these methods are both expensive and laborious. In this study, we isolated DPSCs from a patient undergoing impacted mandibular third molar extraction. We adopted eight different methods of cryopreservation at −80 °C for long term storage of the DPSC aliquots. Various parameters like proliferation, cell death, cell cycle, retention of stemness markers and differentiation potential were studied post cryopreservation period of 1 year. We observed successful recovery of stem cells in every method and a significant difference in proliferation potential and cell death between samples stored by different methods. However, post thaw, all cells retained their stemness markers. All DPSCs stored by different methods were able to differentiate into osteoblast like cells, adipocytes and neural cells. Based on these parameters we concluded that uncontrolled freezing at a temperature of −80 °C is as effective as controlled freezing using ethanol vessels and other cryopreservation methods. To the best of our knowledge, our study provides the first proof of concept that long term storage in uncontrolled freezing of cells at −80 °C in 10 % DMSO does not affect the revival capacity of hDPSCs. This implies that DPSCs may be used successfully for tissue engineering and cell based therapeutics even after long term, uncontrolled cryopreservation. © 2015, Springer Science+Business Media Dordrecht.

Madan N.,Bhojia Dental College and Hospital | Pannu K.,Oral Health science Center
International Journal of Computerized Dentistry | Year: 2011

The success of all-ceramic crowns and increased patient demand for metal-free, tooth-colored restorations has led to the development of many different restorative systems for all-ceramic fixed dental prostheses (FDPs). The most recent core materials for all-ceramic FDPs are the yttrium-tetragonal zirconia polycrystal (Y-TZP)-based materials. Yttrium oxide is a stabilizing oxide added to pure zirconia to stabilize it at room temperature and to generate a multiphase material known as partially stabilized zirconia. This exhibits very high flexural strength and fracture toughness along with good biocompatibility and excellent esthetics. This clinical report describes the use of the Lava All-ceramic system, based on Y-TZP, for the fabrication of two fixed dental prostheses (FDPs) in the maxillary anterior region of the patient, restoring both esthetics and function.

Kirtaniya B.C.,Himachal Dental College | Chawla H.S.,Oral Health science Center | Tiwari A.,Oral Health science Center | Ganguly N.K.,ICMR | Sachdev V.,Himachal Dental College
Journal of Indian Society of Pedodontics and Preventive Dentistry | Year: 2010

In this investigation, serum immunoglobulin G (IgG) and immunoglobulin A (IgA) titers, as well as total immunoglobulin concentration (IgG + IgA + IgM), were found to be raised with the increase in the number of dental caries. Only the total serum antibody titer in high dental caries (HDC) group was found to be significantly raised as compared to no dental carries (NDC) group. Although the IgG and IgA titers were raised in blood with the increased number of caries, the results were not statistically significant. However, we could not find any correlation between serum antibodies and dental caries except that there was an increased trend of serum antibodies to GTF with the increased number of carious lesions.

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