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Newport, United Kingdom

Chrysanthakopoulos N.A.,Maxillofacial and Oral Surgery | Chrysanthakopoulos N.A.,National and Kapodistrian University of Athens
Experimental Oncology | Year: 2016

Aim: The aim of the present case - control study was to examine the possible associations between periodontal disease indices and the risk of lung cancer development in a sample of Greek out-patients referred to a medical and a dental private practice. Materials and Methods: A total of 200 individuals were interviewed and underwent an oral clinical examination, and 64 of them were suffered from several histological types of lung cancer. The estimation of the possible associations between lung cancer as a dependent variable and periodontal disease indices as independent ones was carried out by using a multiple regression analysis model. Results: Probing pocket depth (odds ratio (OR) = 2.72, 95% confidence interval (CI) 1.05-7.06), clinical attachment loss (OR = 3.51, 95% CI 1.30-9.47) bleeding on probing (OR = 1.93, 95% CI 0.98-3.81) were significantly associated with the risk of developing lung cancer. Smoking (OR = 2.49, 95% CI 1.20-5.17) was significantly associated with the mentioned risk, whereas it was consisted as a confounder regarding the estimated associations between moderate/severe clinical attachment loss and presence of bleeding on probing with the risk of developing lung cancer. Conclusion: Probing pocket depth as an index for periodontal disease severity was statistically significantly associated with the risk of developing lung cancer. Source


Allori A.C.,Duke Section of Pediatric Plastic and Craniofacial Surgery | Allori A.C.,In equip | Marcus J.R.,Duke Cleft and Craniofacial Program | Marcus J.R.,Duke University | Bond J.,Maxillofacial and Oral Surgery
Cleft Palate-Craniofacial Journal | Year: 2014

Objective: The learning process for intraoral procedures is arguably more difficult than for other surgical procedures because of the assistant's severely limited visibility. Consequently, trainees may not be able to adequately see and follow all steps of the procedure, and attending surgeons may be less willing to entrust trainees with critical portions of the procedure. In this report, we propose a video-assisted approach to intraoral procedures that improves lighting, visibility, and potential for effective education and training.Design: Technical report (idea/innovation).Setting: Tertiary referral hospital.Patients: Children with cleft palate and velopharyngeal insufficiency requiring surgery.Interventions: Video-assisted palatoplasty, sphincteroplasty, and pharyngoplasty.Main Outcome Measures: Qualitative and semiquantitative educational outcomes, including learner perception regarding "real-time" (video-assisted surgery) and "non-real-time" (videolibrary-based) surgical education.Results: Trainees were strongly in favor of the video-assisted modality in "real-time" surgical training. Senior trainees identified more opportunities in which they had been safely entrusted to perform critical portions of the procedure, corresponding with satisfaction with the learning process scores, and they showed greater comfort/confidence scores related to performing the procedure under supervision and alone.Conclusions: Adoption of the video-assisted approach can be expected to markedly improve the learning curve for surgeons in training. This is now standard practice at our institution. We are presently conducting a full educational technology assessment to better characterize the effect on knowledge acquisition and technical improvement. © 2014 American Cleft Palate-Craniofacial Association. Source


Rocke D.J.,Head and Neck Surgery | Tucci D.L.,Head and Neck Surgery | Marcus J.,Maxillofacial and Oral Surgery | McClennen J.,Duke University | Kaylie D.,Head and Neck Surgery
Otology and Neurotology | Year: 2014

Objective: Auricular defects are challenging to reconstruct with native tissue. We describe operative techniques and complication management for patients undergoing osseointegrated implants for auriculectomy defects and microtia.Setting: Tertiary referral center.Patients: All patients at Duke University Medical Center with auricular defects treated with osseointegrated implants for prosthetic (OIP) auricles from January 1, 2010, until September 16, 2013.Interventions: Osseointegrated implantation for auricular defects.Main Outcome Measure: Description of operative techniques, complications, and complication management.Results: Sixteen patients met inclusion criteria. Five patients had microtia and atresia. Two of these patients had bilateral microtia and atresia and underwent bilateral simultaneous implantation of both OIP and osseointegrated hearing implants (OHIs). Two other microtia/atresia patients underwent simultaneous unilateral OIP and OHI. Eleven patients had unilateral defects from either trauma or skin cancer resection. Three patients received adjuvant radiation before implantation. Complications included tissue overgrowth requiring revision surgery (two patients), inadequate bone stock requiring split calvarial bone graft and later implantation, loss of implant secondary to osteoradionecrosis requiring hyperbaric oxygen therapy, and skin infection requiring antibiotic therapy.Conclusion: Reconstruction of auriculectomy defects and microtia is difficult to accomplish using native tissue. Complications are common, and these complications can have devastating consequences on the final result. Osseointegrated implantation offers an outstanding alternative for reconstructing these defects. We describe our multidisciplinary team approach, examine operative techniques, and focus on the unique challenges of simultaneous and bilateral simultaneous OIP and OHI implantation. © 2014 Otology & Neurotology, Inc. Source


Chrysanthakopoulos N.A.,Maxillofacial and Oral Surgery
Journal of Clinical and Experimental Dentistry | Year: 2012

Objectives: The aim of this study was to estimate the prevalence of dental erosion and to investigate possible associations among dental erosion and medical history, dietary and lifestyle habits in a sample of adolescents in Greece. Study design: The study sample consisted of 770 adolescents, 374 boys and 396 girls aged 13 to 16 years. All individuals were clinically examined and answered questions regarding their medical history, rate and frequency of drinks and food consumption and lifestyle habits. Statistical analysis of the questionnaire items was performed by using the multiple logistic regression analysis model. Results: Two hundreds and sixty adolescents were diagnosed as having dental erosion, giving a prevalence rate 33.8%. The habit of holding drinks in the mouth before swallowing [OR=2.85, 95% CI=1.45-5.58] (p=0.002), the ingestion of acidic drinks at bedtime [OR=0.24, 95% CI=0.11-0.53] (p=0.000), the consumption of carbonated drinks [OR=3.99, 95% CI=1.37-11.59] (p=0.011) and fruit juices [OR=0.12, 95% CI=0.04-0.38] (p=0.000) were the most important associated factors of dental erosion. Conclusions: The prevalence of dental erosion in the study sample was 33.8% while dental erosion experience was associated with frequency and habits of consumption of some dietary components. © Medicina Oral S.L. Source


Jones T.,Maxillofacial and Oral Surgery | Fleming C.,Maxillofacial and Oral Surgery | Llewelyn J.,Maxillofacial and Oral Surgery
British Journal of Oral and Maxillofacial Surgery | Year: 2011

We reviewed patient satisfaction with the management of oral vascular lesions using a potassium titanyl phosphate (KTP) laser. Questionnaires consisting of 10 questions were given to 95 patients who had had laser treatment for oral vascular lesions between September 2007 and July 2009. A five-point scale ranging from poor (1) to very good (5) was used for the responses. Seventy-one percent of patients responded. Overall, they were very satisfied with the process of laser treatment (mean score more than 4.5/5), but were less satisfied with the levels of comfort 24 h after the procedure (mean score 3.7/5), and after one week (mean score 4.2/5). As postoperative discomfort was highlighted as an area of dissatisfaction for some patients, modifications to aftercare instructions may improve this aspect of the service. © 2010 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved. Source

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