Dunfermline, United Kingdom
Dunfermline, United Kingdom

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Patent
Optos PLC | Date: 2015-05-01

A method of determining a measurement of at least one cell type in an eye, comprising (i) obtaining a map of the cell type in the eye, (ii) obtaining a representation of the retina of the eye, (iii) matching the eye cell type map to the representation of the retina of the eye, (iv) defining a region of interest on the representation of the retina of the eye, (v) calculating a size of the region of interest on the representation of the retina of the eye, (vi) using the matched eye cell type map and the size of the region of interest to determine a measure of the cell type in the region of interest of the retina of the eye.


Patent
Optos PLC | Date: 2016-07-28

The present disclosure provides a method of processing an image comprising receiving a measured image, producing a sharpened image by filtering the measured image to increase its sharpness, and transforming the sharpened image using at least one selected geometric transformation. The present disclosure further provides a computer readable media storing program instructions which, when executed, perform the method of processing an image and a system for processing an image comprising a receiving module which receives a measured image, a sharpening module which produces a sharpened image by filtering the measured image to increase its sharpness, and a transformation module which transforms the sharpened image using at least one selected geometric transformation.


Patent
Optos PLC | Date: 2014-11-26

A scanning laser ophthalmoscope (10) for scanning the retina of an eye (22) is provided comprising a light source (12) emitting a beam of light (13), scan relay elements (14, 16, 18, 20), wherein the light source and the scan relay elements provide a two-dimensional scan of the light beam which is transferred from an apparent point source at a pupillary point of the eye to the retina of the eye, and a static aberration correction element (30) which has a shape defined to provide correction of aberrations of at least some of the scan relay elements and a location within the ophthalmoscope chosen to provide correction of aberrations of at least some of the scan relay elements, which location maintains transfer of the beam of light from the apparent point source at the pupillary point of the eye to the retina of the eye. The invention further provides an aberration correction element (30) and a method of determining a shape of the aberration correction element.


Patent
Optos PLC | Date: 2016-02-02

A method of reducing jitter error in a laser scanning system adapted to produce a scanned image including a number of lines of an object. The method includes the steps of providing a reference object arranged such that the scanned image produced by the laser scanning system includes a reference image of the reference object, processing the reference image to calculate an error arising from non-repeatable displacement of the lines of the reference image, and adjusting at least one operating parameter of the laser scanning system in response to the calculated error.


Patent
Optos PLC | Date: 2014-06-25

A method of determining a correction for distortion in eye representations of an ophthalmoscope comprising(i) constructing an optical description of a system comprising the ophthalmoscope and a model eye,(ii) passing a ray through the system onto a surface of the model eye,(iii) calculating an actual measurement of the ray at the surface,(iv) determining a horizontal scanning angle and a vertical scanning angle of the system for the ray,(v) calculating an expected measurement of the ray at the surface using the horizontal scanning angle and vertical scanning angle of the system,(vi) repeating steps (ii) to (v) for a plurality of further rays, and(vii) comparing the actual measurements of the rays at the surface with corresponding expected measurements of the rays at the surface to determine the correction for distortion in eye representations of the ophthalmoscope.


Patent
Optos PLC | Date: 2014-02-19

An image processing apparatus uses first and second digital vascular image data to register two images. The two images may be from different imaging modes. The first and second images are processed with a two-dimensional, directional filter (500) that has the effect of producing clusters of orthogonally adjacent image data points in which the magnitude of an intensity gradient between each orthogonally adjacent image data point is less than a predetermined value. Subsequently, common clusters are identified between the first and second image data using a corner detecting algorithm (600). The directional filter produces stepping features, where vascular features would otherwise appear with smooth edges. These numerous features are identified by the corner detecting algorithm and can be used (1000) for registering common clusters between the first and second image data. The filter may be a rotating Gabor filter matched to vascular features in the images.


Patent
Optos PLC | Date: 2014-05-01

A method of determining a geometrical measurement of a retina of an eye, comprising obtaining a two dimensional representation of at least a portion of the retina of the eye (34), deriving a geometrical remapping which converts the two dimensional representation of the retinal portion to a three dimensional representation of the retinal portion (36), using one or more coordinates of the two dimensional representation of the retinal portion to define the geometrical measurement to be taken of the retina on the two dimensional representation (38), using the geometrical remapping to convert the or each coordinate of the two dimensional representation of the retinal portion to an equivalent coordinate of the three dimensional representation of the retinal portion (40), and using the or each equivalent coordinate of the three dimensional representation of the retinal portion to determine the geometrical measurement of the retina of the eye (42).


Patent
Optos PLC | Date: 2016-02-02

A laser scanning system adapted to produce a scanned image including a number of lines of an object. A method includes the steps of providing a reference object arranged such that the scanned image produced by the laser scanning system includes a reference image of the reference object, processing the reference image to calculate an error arising from non-repeatable displacement of the lines of the reference image, and adjusting at least one operating parameter of the laser scanning system in response to the calculated error.


Patent
Optos PLC | Date: 2016-01-20

Apparatus for illuminating the retina of an eye. The apparatus includes an illumination device and a lens system. The illumination device and the lens system combine to provide incident illumination from an apparent point source located within the lens system. The apparatus also includes an illumination transfer device. The illumination transfer device has two foci and the apparent point source of the lens system is provided at a first focus point of the illumination transfer device and an eye is accommodated at a second focus point of the illumination transfer device. The illumination transfer device transfers the incident illumination from the apparent point source into the eye to illuminate the retina.


Patent
Optos PLC | Date: 2014-11-05

A method of determining a geometrical measurement of a retina of an eye, comprising obtaining a two dimensional representation of at least a portion of the retina of the eye (34), deriving a geometrical remapping which converts the two dimensional representation of the retinal portion to a three dimensional representation of the retinal portion (36), using one or more coordinates of the two dimensional representation of the retinal portion to define the geometrical measurement to be taken of the retina on the two dimensional representation (38), using the geometrical remapping to convert the or each coordinate of the two dimensional representation of the retinal portion to an equivalent coordinate of the three dimensional representation of the retinal portion (40), and using the or each equivalent coordinate of the three dimensional representation of the retinal portion to determine the geometrical measurement of the retina of the eye (42).

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