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Sudheer Reddy K.,Acharya Nagarjuna University | Kantha Reddy M.,Operations | Sitaramulu V.,Swarana Bharathi Institute of Technology
2013 International Conference on Information Communication and Embedded Systems, ICICES 2013

Web Usage Mining (WUM) is one of the categories of data mining technique that identifies usage patterns of the web data, so as to perceive and better serve the requirements of the web applications. The working of WUM involves three steps - preprocessing, pattern discovery and analysis. The first step in WUM - Preprocessing of data is an essential activity which will help to improve the quality of the data and successively the mining results. This research paper studies and presents several data preparation techniques of access stream even before the mining process can be started and these are used to improve the performance of the data preprocessing to identify the unique sessions and unique users. The methods proposed will help to discover meaningful pattern and relationships from the access stream of the user and these are proved to be valid and useful by various research tests. The paper is concluded by proposing the future research directions in this space. © 2013 IEEE. Source

Chung K.,Operations | Jang K.,University of California at Berkeley | Madanat S.,University of California at Berkeley | Washington S.,Queensland University of Technology
Transportation Research Part A: Policy and Practice

In previous research (Chung et al., 2009), the potential of the continuous risk profile (CRP) to proactively detect the systematic deterioration of freeway safety levels was presented. In this paper, this potential is investigated further, and an algorithm is proposed for proactively detecting sites where the collision rate is not sufficiently high to be classified as a high collision concentration location but where a systematic deterioration of safety level is observed. The approach proposed compares the weighted CRP across different years and uses the cumulative sum (CUSUM) algorithm to detect the sites where changes in collision rate are observed. The CRPs of the detected sites are then compared for reproducibility. When high reproducibility is observed, a growth factor is used for sequential hypothesis testing to determine if the collision profiles are increasing over time. Findings from applying the proposed method using empirical data are documented in the paper together with a detailed description of the method. © 2011 Elsevier Ltd. Source

Nalugo M.,Akron Children's Hospital | Craner D.R.,Akron Children's Hospital | Craner D.R.,Northeast Ohio Medical University | Schwachter M.,Operations | And 2 more authors.
European Journal of Pediatric Surgery

Telemedicine is a broad term and has recently become a household term in the medical field. However, there are many interpretations as to what the term "telemedicine" means. There are many facets to telemedicine and here we describe all of the elements of telemedicine, a glossary of terms, and how they relate to pediatric surgery. © Georg Thieme Verlag KG. Source

Trim R.S.,Operations | Jentzen J.,University of Michigan | Penn G.,Milwaukee County Medical Examiners Office
American Journal of Forensic Medicine and Pathology

Opinions based on toxicology results are dependent, in part, upon the quality of the specimen's acquisition, storage, and chain of custody. The responsibility for these factors is often delegated to tissue and eye bank technicians. These technicians are not employees of the medical examiner (ME)'s office and may have no documented training related to the proper acquisition and handling of retained toxicology specimens. Medical examiners and coroners often request tissue recovery technicians to provide them with these toxicology samples when the tissue recovery is performed before autopsy. This practice helps facilitate donation and is convenient for the ME, but there may be unexpected implications for both the technicians and the ME that deserve further consideration. This article highlights the relevant issues in the postmortem recovery of biological samples for toxicology analysis and makes recommendations for the practice. © 2013 by Lippincott Williams & Wilkins. Source

Broyles R.,Operations | Rodden L.,CSL Behring LLC | Riley P.,CSL Behring LLC | Berger M.,CSL Behring LLC
Postgraduate Medicine

Aims: We reviewed the intravenous immunoglobulin G (IVIG) dispensing records of a specialty pharmacy to characterize the IVIG treatment regimens used for chronic inflammatory demyelinating polyneuropathy (CIDP) and myasthenia gravis (MG) in community practice. Methods: Anonymized records were selected based on International Classification of Diseases, Ninth Revision (ICD-9) codes and IVIG treatment for. 1 month. Each patient's immunoglobulin G (IgG) dose per infusion (mg/kg/dose) was multiplied by the number of doses per month (30.5 days divided by the dosing interval in days) to yield the total monthly dose (mg/kg/month). Data were analyzed and summarized using descriptive statistics. Results: Forty-six patients (median age, 56.5 years; range, 8-86 years) fulfilled the inclusion criteria. Thirty-one patients with CIDP received IgG at 7- to 92-day intervals (mean [standard deviation (SD)], 28 [16] days). The mean (SD) IgG dose was 75 (60) g/dose, equivalent to 866 (623) mg/kg/dose and 1145 (778) mg/kg/month. Six patients with stable MG received IVIG or subcutaneous IgG at 3.5- to 61-day intervals (28 [20] days) at a mean (SD) IgG dose of 39 (15) g/dose, equivalent to 405 (108) mg/kg/dose and 783 (680) mg/kg/month. Nine patients with MG with acute exacerbations received IgG at 7- to 42-day intervals (22 [12] days) at a mean (SD) dose of 40 (21) g/dose, equivalent to 403 (172) mg/kg/dose and 641 (288) mg/kg/month. One patient with CIDP and 4 patients with MG were treated with weekly subcutaneous IgG injections. Conclusion: Although patients with CIDP and MG are treated with mean total monthly IgG doses similar to those approved by the US Food and Drug Administration, the individual doses and intervals vary considerably, suggesting that physicians may be adjusting IgG dosing according to each patient's clinical condition and treatment response. Further study is necessary to determine the criteria used to adjust IgG treatment regimens and whether these adjustments optimize clinical outcomes while limiting overall costs. © Postgraduate Medicine. Source

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