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New Delhi, India

Kunal S.,University of Delhi | Pilaniya V.,University of Delhi | Jain S.,Oncquest Laboratory | Shah A.,University of Delhi
BMJ Case Reports | Year: 2016

Organising pneumonia ( OP) is a distinct but uncommon entity with characteristic clinicoradiological features and histological findings. When the aetiology of OP remains unknown, it is termed as cryptogenic OP (COP). COP is seen in the majority of patients with OP and usually observed in non/former smokers. A 54-year-old man, a smoker, presented with breathlessness, cough and mucoid sputum. Imaging demonstrated unilateral 'Crazy-paving' pattern in the left upper lobe and left-sided effusion. In addition, paraseptal emphysema and left lower lobe bullae along with very severe obstructive ventilatory defect and impaired diffusion suggested chronic obstructive pulmonary disease (COPD). Transbronchial biopsy was suggestive of OP. In the absence of a definite aetiology, a diagnosis of COP associated with COPD was established. COP presenting as a unilateral 'Crazy-paving' pattern is yet to be documented. To the best of our knowledge, this is the first detailed description of COP presenting as unilateral 'Crazy-paving' pattern associated with COPD. ©2016 BMJ Publishing Group. All rights reserved.

Joseph P.,Oncquest Laboratory | Goyal R.,Oncquest Laboratory | Bansal P.,Oncquest Laboratory | Parmar R.,Oncquest Laboratory | Dutt S.,Oncquest Laboratory
Journal of Clinical and Diagnostic Research | Year: 2015

Gastrointestinal stromal tumours (GIST) are the most common mesenchymal neoplasms located in the alimentary tract. Stromal tumours that arise outside the gastrointestinal tract as primary tumour are designated as extra-gastrointestinal stromal tumours (EGIST). The EGIST are located in mesentry, omentum, retroperitoneum and rarely in pancreas. Only 19 cases of pancreatic EGIST (pEGIST) have been reported in the literature. Of these, there were only two cases of pEGIST with documentation of molecular alteration in C-Kit gene. We here report a third case of primary pEGIST with documentation of C-kit mutation. © 2015, Journal of Clinical and Diagnostic Research. All right reserved.

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