The Okinawa Institute of Science and Technology Graduate University is an interdisciplinary graduate school located in Onna, Okinawa Prefecture, Japan. The school offers a 5-year PhD program in Science. Over half of the faculty and students are recruited from outside Japan, and all education and research is conducted entirely in English.The university has no departments—OIST researchers conduct multi-disciplinary research in neuroscience, mathematical and computational science, physics, chemistry, integrative biology and molecular, cell, and developmental biology. The university received accreditation on November 1, 2011, and began classes in September 2012.OIST relies on public subsidies paid by the Japanese government. The government subsidy for OIST comes in two areas: a subsidy for operations and a subsidy for facilities. Wikipedia.
Okinawa Institute of Science and Technology | Date: 2016-08-15
The present invention relates to a method for screening a compound that inhibits secretion of toxins into host-cell cytoplasm by virulent bacteria using a needle type III secretion system. The compound of the invention is selected by screening for a compound which interacts with a loop region of the cytoplasmic domain of the membrane protein FlhB from Salmonella typhimurium or a paralog thereof Compositions including the compound of the invention, use of the compound, and methods of treating disorders caused by virulent bacteria are also provided.
Okinawa Institute of Science and Technology | Date: 2015-04-10
A method for identifying a subject of Acropora genus to an Acropora species comprises of detecting one or more microsatellite loci in the genome of the subject, wherein the microsatellite loci are selected from the group consisting of a microsatellite locus 8346m3 and others. A method for quantifying an index of level of chimerism of a coral colony restored by transplanting an Acropora first coral colony of an Acropora species into a second coral colony in need of restoration that belongs to the same species as the first coral colony comprises of identifying one or more microsatellite loci whose PCR fragment size, amplified with genomic DNA derived from the first coral colony as template, is different from the PCR fragment size amplified with genomic DNA derived from the second coral colony.
Agency: Cordis | Branch: FP7 | Program: CPCSA | Phase: ICT-2013.9.9 | Award Amount: 72.73M | Year: 2013
Understanding the human brain is one of the greatest challenges facing 21st century science. If we can rise to the challenge, we can gain profound insights into what makes us human, develop new treatments for brain diseases and build revolutionary new computing technologies. Today, for the first time, modern ICT has brought these goals within sight. The goal of the Human Brain Project, part of the FET Flagship Programme, is to translate this vision into reality, using ICT as a catalyst for a global collaborative effort to understand the human brain and its diseases and ultimately to emulate its computational capabilities. The Human Brain Project will last ten years and will consist of a ramp-up phase (from month 1 to month 36) and subsequent operational phases.\nThis Grant Agreement covers the ramp-up phase. During this phase the strategic goals of the project will be to design, develop and deploy the first versions of six ICT platforms dedicated to Neuroinformatics, Brain Simulation, High Performance Computing, Medical Informatics, Neuromorphic Computing and Neurorobotics, and create a user community of research groups from within and outside the HBP, set up a European Institute for Theoretical Neuroscience, complete a set of pilot projects providing a first demonstration of the scientific value of the platforms and the Institute, develop the scientific and technological capabilities required by future versions of the platforms, implement a policy of Responsible Innovation, and a programme of transdisciplinary education, and develop a framework for collaboration that links the partners under strong scientific leadership and professional project management, providing a coherent European approach and ensuring effective alignment of regional, national and European research and programmes. The project work plan is organized in the form of thirteen subprojects, each dedicated to a specific area of activity.\nA significant part of the budget will be used for competitive calls to complement the collective skills of the Consortium with additional expertise.
Agency: GTR | Branch: EPSRC | Program: | Phase: Fellowship | Award Amount: 807.01K | Year: 2015
Complex fluid flows are ubiquitous in both the natural and man-made worlds. From the pulsatile flow of blood through our bodies, to the pumping of personal products such as shampoos or conditioners through complex piping networks as they are processed. For such complex fluids the underlying microstructure can give rise to flow instabilities which are often totally absent in simple Newtonian fluids such as water or air. For example, many wormlike micellar surfactant (soap/detergent) systems are known to exhibit shear-banding where the homogenous solution splits into two (or more) bands of fluid: such flows are often unstable to even infinitesimally small perturbations. At higher pump speeds the flows can develop chaotic motion caused by the elastic normal-stresses developed in flow. Such elastic turbulence can also develop for other flowing complex fluids, such as polymer solutions and melts, and give rise to new phenomena. Often such instabilities are unwelcome, for example in rheometric devices when the aim is to measure material properties or in simple pumping operations when they can give rise to unacceptably large pressure drops and prevent pumping. In other cases they can give rise to enhanced mixing of heat and mass which would otherwise be difficult to achieve (e.g. microfluidics applications).
Okinawa Institute of Science, Technology, SBX Corporation and The Systems Biology Institute | Date: 2015-09-16
According to the present invention, in a plurality of data analysis apparatuses communicatively coupled to one another, a database is accessed at a given access level. Based on the data acquired from the database, an application program is executed to perform data analysis. Communication control is performed to allow transmission and reception of a data analysis result with respect to another data analysis apparatus at a different access level.
Okinawa Institute of Science, Technology and The Systems Biology Institute | Date: 2015-04-22
The present invention acquires compound structure data and candidate protein structure data on a candidate protein serving as a candidate for interaction with the compound. The present invention calculates a binding strength between the candidate protein and the compound using a docking simulation method, determines a predicted binding strength corresponding to the binding strength predicted by making a comprehensive evaluation of the binding strength, and determines a predicted protein corresponding to the candidate protein predicted to interact with the compound. The present invention calculates an interaction strength using a binding strength simulation method and determines a predicted interaction strength corresponding to the interaction strength predicted by making the comprehensive evaluation of the interaction strength.