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Mikkelsen S.S.,Technical University of Denmark | Panzarin V.,OIE Reference Laboratory for Viral Encephalopathy and Retinopathy | Jonstrup S.P.,Technical University of Denmark | Bigarre L.,Fish Viral Pathologies Unit | And 4 more authors.
Journal of Fish Diseases | Year: 2015

Viral nervous necrosis (VNN) is a severe neuropathological disease affecting a broad variety of finfish species worldwide. The causative agents of VNN are small viruses with a bi-segmented RNA genome known as betanodaviruses. At least four species with distinct but yet insufficiently characterized epidemiological features are recognized. The spread of VNN to an increasing number of host species, its wide geographic extent and its economical and ecological impacts justify the importance of collating as much molecular data as possible for tracing the origin of viral isolates and highlight the need for a freely accessible tool for epidemiological and molecular data sharing and consultation. For this purpose, we established a web-based specific database using the www.fishpathogens.eu platform, with the aim of collecting molecular and epidemiological information on VNN viruses, with relevance to their control, management and research studies. © 2015 John Wiley & Sons Ltd. Source

Bovo G.,OIE Reference Laboratory for Viral Encephalopathy and Retinopathy | Gustinelli A.,University of Bologna | Quaglio F.,University of Padua | Gobbo F.,OIE Reference Laboratory for Viral Encephalopathy and Retinopathy | And 5 more authors.
Diseases of Aquatic Organisms | Year: 2011

Viral encephalopathy and retinopathy (VER), otherwise known as viral nervous necrosis (VNN), is a neuropathological condition affecting >40 species of fish. Although VER affects mainly marine fish, the disease has also been detected in certain species reared in freshwater environments. There are relatively few reports concerning the disease in freshwater species, and there is not much information on clinical signs. Nevertheless, the most common clinical findings reported from affected freshwater species are consistent with the typical signs observed in marine species. In this paper we describe the main clinical signs and the laboratory results associated with the detection of a beta - nodavirus in hybrid striped bass × white bass (Morone saxatilis × Morone chrysops) and largemouth bass Micropterus salmoides, reared in a freshwater environment. We also detected the virus by real-time PCR and isolated it in cell culture from a batch of pike-perch Sander lucioperca farmed in the same system. © Inter-Research 2011. Source

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