Ironton, OH, United States

Ohio University Southern

www.ohio.edu/southern
Ironton, OH, United States

Ohio University Southern Campus is located at 1804 Liberty Avenue in Ironton, Ohio. While not as large as the main Ohio University campus located in Athens, Ohio, several degree programs are offered. The Southern Campus also features an extension located in Proctorville, Ohio, a Nature Center, and the Ohio Horse Park located in Franklin Furnace, Ohio just off U.S. 52. OUS also has an on campus eating area called "The Paddock".The University began in 1956 when it hosted college-level classes in Ironton High School with an initial enrollment of 90 students. Wikipedia.

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Lai H.-J.,West Virginia University | Lai H.-J.,Xinjiang University | Lemos M.,Federal University of Pernambuco | Reid T.J.,University of Mississippi | And 2 more authors.
European Journal of Combinatorics | Year: 2011

Bixby and Cunningham showed that a 3-connected binary matroid M is graphic if and only if every element belongs to at most two non-separating cocircuits. Likewise, Lemos showed that such a matroid M is graphic if and only if it has exactly r(M)+1 non-separating cocircuits. Hence the presence in M of either an element in at least three non-separating cocircuits, or of at least r(M)+2 non-separating cocircuits, implies that M is non-graphic. We provide lower bounds on the size of the set of such elements, and on the number of non-separating cocircuits, in such non-graphic binary matroids. A computationally efficient method for finding such lower bounds for specific minor-closed classes of matroids is given. Applications of this method and other results on sets of obstructions to a binary matroid being graphic are given. © 2011 Elsevier Ltd.


Zhang L.,Hohai University | Shao Y.,Ohio University Southern | Zhu R.,South-Central University for Nationalities | Yuan J.,Nanjing University | Wang H.,Hohai University
Sensor Letters | Year: 2013

Wireless sensor network (WSN) has many potential applications in surveillance systems for detecting a target or monitoring a physical phenomenon in a region. In these applications, node deployment is one of the fundamental problems. If the monitoring region is relatively large compared with sensing range and transmission range of sensors, then a large number of sensors are required to detect events and deal with them. Hence, how to deploy sensors is very important. Traditionally, static sensors are deployed to cover the monitoring area, and mobile sensors are used to improve the coverage of the area. In this paper, we will use hybrid WSN which contains both static sensors and mobile sensors to detect delay tolerant events and deal with them. A delay tolerant event is an event that can tolerate a limited time delay to be detected after it happens, and during the delay time period, the event usually spreads quickly. Firstly, we formulate the sensor node deployment for full detection problem on delay tolerant event into the minimum disk cover problem, and prove that it is NP-complete. Then, we give an approximation algorithm with a constant factor for it. Our work is different from the previous works, for we aim at how to deploy static sensors and mobile sensors to achieve the full detection on delay tolerant events, rather than the full coverage on area. The theoretical analysis combined with the simulations verify the efficiency of our proposed algorithms.Copyright © 2013 American Scientific Publishers. Copyright © 2013 American Scientific Publishers.


A major goal of The Patient Protection and Affordable Care Act is to broaden health care access through the extension of insurance coverage. However, little attention has been given to growing disparities in access to health care among the insured, as trends to reduce benefits and increase cost sharing (deductibles, co-pays) reduce affordability and access. Through a political economic perspective that critiques moral hazard, this article draws from ethnographic research with the United Steelworkers (USW) at a steel mill and the Retail, Wholesale and Department Store Union (RWDSU) at a food-processing plant in urban Central Appalachia. In so doing, this article describes difficulties of health care affordability on the eve of reform for differentially insured working families with employer-sponsored health insurance. Additionally, this article argues that the proposed Cadillac tax on high-cost health plans will increase problems with appropriate health care access and medical financial burden for many families. © 2016 American Anthropological Association.


Pennington N.,Ohio University Southern | Johnson M.,Ohio University Southern | Delaney E.,Ohio University Southern | Blankenship M.B.,Ohio University Southern
Journal of School Nursing | Year: 2010

A new hazard for adolescents is the negative health effects of energy drink consumption. Adolescents are consuming these types of drinks at an alarming amount and rate. Specific effects that have been reported by adolescents include jitteriness, nervousness, dizziness, the inability to focus, difficulty concentrating, gastrointestinal upset, and insomnia. Health care providers report that they have seen the following effects from the consumption of energy drinks: dehydration, accelerated heart rates, anxiety, seizures, acute mania, and strokes. This article is a comprehensive literature review on the health effects of energy drinks. Findings from this article indicate the need for educational intervention to inform adolescents of the consequences of consuming these popular drinks. School nurses are in a unique position to teach adolescents about the side effects and possible health issues that can occur when energy drinks are consumed. © 2010 The Author(s).


PubMed | Ohio University Southern
Type: Journal Article | Journal: Medical anthropology quarterly | Year: 2016

A major goal of The Patient Protection and Affordable Care Act is to broaden health care access through the extension of insurance coverage. However, little attention has been given to growing disparities in access to health care among the insured, as trends to reduce benefits and increase cost sharing (deductibles, co-pays) reduce affordability and access. Through a political economic perspective that critiques moral hazard, this article draws from ethnographic research with the United Steelworkers (USW) at a steel mill and the Retail, Wholesale and Department Store Union (RWDSU) at a food-processing plant in urban Central Appalachia. In so doing, this article describes difficulties of health care affordability on the eve of reform for differentially insured working families with employer-sponsored health insurance. Additionally, this article argues that the proposed Cadillac tax on high-cost health plans will increase problems with appropriate health care access and medical financial burden for many families.


PubMed | Ohio University Southern
Type: Journal Article | Journal: Journal of pediatric nursing | Year: 2015

Recent statistics show an increasing trend of electronic cigarette usage among adolescents. Despite common misconceptions, electronic cigarette use does not reduce cigarette use among adolescents and can potentially increase cigarette dependence via nicotine addiction and modeling of smoking behaviors. Pediatric nurses and health care providers should be aware of the popularity and safety concerns of electronic cigarettes so that they can properly provide education regarding the possible negative health effects of adolescent electronic cigarette use, raise awareness of this public health concern, and impact policies in their communities.


PubMed | University of Cincinnati, Southern Medical University and Ohio University Southern
Type: Journal Article | Journal: PloS one | Year: 2014

Mesenchymal stem cells (MSCs) have potential application for the treatment of ischemic heart diseases. Besides differentiation properties, MSCs protect ischemic cardiomyocytes by secretion of paracrine factors. In this study, we found exosomes enriched with miR-22 were secreted by MSCs following ischemic preconditioning (Exo(IPC)) and mobilized to cardiomyocytes where they reduced their apoptosis due to ischemia. Interestingly, by time-lapse imaging, we for the first time captured the dynamic shedding of miR-22 loaded exosomes from cytosol to extracellular space. Furthermore, the anti-apoptotic effect of miR-22 was mediated by direct targeting of methyl CpG binding protein 2 (Mecp2). In vivo data showed that delivery of Exo(IPC) significantly reduced cardiac fibrosis. Our data identified a significant benefit of Exo(IPC) for the treatment of cardiac diseases by targeting Mecp2 via miR-22.


PubMed | Ohio University Southern
Type: Journal Article | Journal: Journal of strength and conditioning research | Year: 2016

Hyde, PN, Kendall, KL, Fairman, CM, Coker, NA, Yarbrough, ME, and Rossi, SJ. Utilization of B-mode ultrasound as a body fat estimate in collegiate football players. J Strength Cond Res 30(12): 3525-3530, 2016-The purpose of the present study was to validate a 7-site ultrasound imaging protocol to predict the percent body fat (%BF) in a division I football team. Body composition was estimated by ultrasound, 7-site skinfolds, and the 3-compartment-water (3C-W) model of Siri, using bioimpedance spectroscopy to estimate the total body water and air displacement plethysmography (using BODPOD) to determine the body density. Pearsons product-moment correlation analyses were run to determine correlations between Ultrasound and the criterion 3C-W, and between the Skinfold and Ultrasound. Strong positive correlations were observed between Skinfold and Ultrasound (r = 0.984; p < 0.001). Furthermore, a strong positive correlation was observed between Ultrasound and %BF from 3C-W (r = 0.878; p < 0.001). Based on the significant correlation analysis, a linear regression equation was developed to predict the %BF from Ultrasound, using %BF from the 3C-W model as the dependent variable: %BF = 6.194 + (0.096 Ultrasound); standard error of the estimate (SEE) = 2.97%. Cross-validation analyses were performed using an independent sample of 29 players. The mean observed %BF from the 3C-W model and the mean predicted %BF were 18.32 6.26% and 18.78 6.22%, respectively. The constant error, SEE, and validity coefficient (r) were 0.87%, 2.64%, and 0.91%, respectively. The total error was 2.87%. The positive relationship between ultrasound measurements and the 3C-W model suggests that ultrasound imaging may be a practical alternative to predicting %BF in division I football players.


PubMed | Cincinnati Childrens Hospital Medical Center, University of Alberta, University of Cincinnati, Southern Medical University and Ohio University Southern
Type: Journal Article | Journal: PloS one | Year: 2015

The GII.4 noroviruses (NoVs) are a single genotype that is responsible for over 50% of NoV gastroenteritis epidemics worldwide. However, GII.4 NoVs have been found to undergo antigenic drifts, likely selected by host herd immunity, which raises an issue for vaccine strategies against NoVs. We previously characterized GII.4 NoV antigenic variations and found significant levels of antigenic relatedness among different GII.4 variants. Further characterization of the genetic and antigenic relatedness of recent GII.4 variants (2008b and 2010 cluster) was performed in this study. The amino acid sequences of the receptor binding interfaces were highly conserved among all GII.4 variants from the past two decades. Using serum samples from patients enrolled in a GII.4 virus challenge study, significant cross-reactivity between major GII.4 variants from 1998 to 2012 was observed using enzyme-linked immunosorbent assays and HBGA receptor blocking assays. The overall abilities of GII.4 NoVs to bind to the A/B/H HBGAs were maintained while their binding affinities to individual ABH antigens varied. These results highlight the importance of human HBGAs in NoV evolution and how conserved antigenic types impact vaccine development against GII.4 variants.


Stem cell-based therapy is a promising intervention for ischemic heart diseases. However, the functional integrity of stem cells is impaired in an ischemic environment. Here, we report a novel finding that heat shock significantly improves Sca-1(+) stem cell survival in an ischemic environment by the regulation of the triangle: heat shock factor 1 (HSF1), HSF1/miR-34a, and heat shock protein 70 (HSP70). Initially we prove that HSP70 is the key chaperone-mediating cytoprotective effect of heat shock in Sca-1(+) cells and then we establish miR-34a as a direct repressor of HSP70. We found that miR-34a was downregulated in heat shocked Sca-11 stem cells (HSSca-11 cells) [corrected]. Intriguingly, we demonstrate that the downregulation of miR-34a is attributed to HSF1-mediated epigenetic repression through histone H3 Lys27 trimethylation (H3K27me3) on miR-34a promoter. Moreover, we show that heat shock induces exosomal transfer of HSF1 from Sca-1(+) cells, which directs ischemic cardiomyocytes toward a prosurvival phenotype by epigenetic repression of miR-34a. In addition, our in vivo study demonstrates that transplantation of (HS) Sca-1(+) cells significantly reduces apoptosis, attenuates fibrosis, and improves global heart functions in ischemic myocardium. Hence, our study provides not only novel insights into the effects of heat shock on stem cell survival and paracrine behavior but also may have therapeutic values for stem cell therapy in ischemic heart diseases.

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