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Louisville, KY, United States

Gillier T.,Office of Technology Transfer
Journal of Product Innovation Management | Year: 2010

For a few decades now, firms have had to innovate in cooperation with other organizations. According to the literature on co-innovation, a new form of innovation partnership is now emerging: the exploratory partnership. This type of partnership is the most often established in the early stages of the design process and faces high levels of uncertainty and instability. This paper deals with a strategic design tool, OPERA, based on a recent general design theory named C-K theory. That theory models design reasoning by suggesting a fundamental distinction between concepts (propositions about novel objects) and knowledge (propositions about known objects). According to the theory, the interaction and co-evolution of concepts and knowledge is the main engine through which design progresses. The paper proposes to extend that theory to understand and to act in innovation community context. OPERA enables power holders and design teams to drive innovation projects by providing them with an overview of explored and unexplored concepts and of the activation and production of skills and knowledge. This cartographic system was tested by MINATEC IDEAs Laboratory, a Cross-Industry Exploratory Partnership, over a 15-month period. The innovative platform is composed of partners from different sectors (e.g., energy, technology research center, sports, telecommunications) and aims to build innovative projects and to devise new products and services based on micronanotechnologies. Facing such diversities, actors of MINATEC IDEAs Laboratory used OPERA to see how each project is progressing, the contribution of each project to the global exploration process, and the complementarities between the projects. Such representations enable the committee to identify the main value of a project, any knowledge gaps and the synergies between projects. From a collective point of view, OPERA permits to MINATEC IDEAs Laboratory's members to indicate their favorite concepts and knowledge areas and to estimate converging and diverging interests. © 2010 Product Development & Management Association.

Office of Technology Transfer and Johns Hopkins University | Date: 2013-05-24

The ability to form and maintain gradients is essential for the study of response of cells to various stimuli. The invention includes devices and methods for the high-throughput, reproducible formation of gradients for the study of living cells. The invention includes microfluidics device with a lest chamber having a depth flanked by flow-through channels having a deeper depth. Flow of two different fluids through the flow-through channels results in the creation of a gradient by diffusion across the test chamber having essentially no flow.

Office of Technology Transfer | Date: 2013-01-22

An energy-efficient CAM architecture provides increased speed of searching, reduced power consumption, or a tuned combination of increased speed of searching and reduced power consumption. The CAM comprises a plurality of CAM banks, a plurality of Bloom filters, each Bloom filter associated with a content addressable memory bank, each Bloom filter recording elements inserted into an associated content addressable memory bank, wherein the size of each Bloom filter is configured to reduce energy or power consumption of the content addressable memory apparatus. The size of each Bloom filter may be configured to reduce energy or power consumption of the content addressable memory apparatus.

Office of Technology Transfer | Date: 2013-05-07

An apparatus for dilating an upper esophageal sphincter. The apparatus includes an elongated expandable member having a cross-section shaped to support a natural shape of an upper esophageal sphincter. A catheter extends from the elongated inflatable member.

Office of Technology Transfer and Institute For Cancer Research D B A The Research Institute Of Fox Chase Cancer Center Fox Chase C | Date: 2013-08-19

Systems, methods, and computer readable media for diagnosing or characterizing a genetic predisposition to develop cancer, including cancers of the BAP1 cancer syndrome, are provided. Nucleic acids comprising a germline nucleic acid sequence encoding the BRCA1 associated protein 1 (BAP1) are sequenced or probed to determine if the nucleic acid sequence includes alterations that predispose a subject to develop cancer.

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