Office of Spill Prevention and Response Fish and Wildlife Water Pollution Control Laboratory

Rancho Cordova, CA, United States

Office of Spill Prevention and Response Fish and Wildlife Water Pollution Control Laboratory

Rancho Cordova, CA, United States

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Van Scoy A.R.,University of California at Davis | Yu Lin C.,National Taiwan University | Anderson B.S.,University of California at Davis | Philips B.M.,University of California at Davis | And 7 more authors.
Ecotoxicology and Environmental Safety | Year: 2010

Crude oil spills from tankers remain a serious threat along coastal California. Resource managers require information on the acute toxicity of treated and untreated oil, and their sublethal effects on wildlife. This investigation compared the toxic actions of the water-accommodated fraction (WAF) and the chemically-enhanced WAF (CEWAF; Corexit 9500) of Prudhoe Bay crude oil in pre-smolt Chinook salmon (Oncorhynchus tshawytscha) via nuclear magnetic resonance (NMR)-based metabolomics. Metabolite profiles from muscle samples, after 96h exposures, were measured using 1D 1H NMR and compared via principal component analysis. It was determined that both WAF and CEWAF produced similar profiles in which amino acids, lactate and ATP comprised the highest intensity signals. Overall, metabolic substrates and growth measurements did not show residual effects of short-term exposure on long-term development. In conclusion, the 96h LC 50s indicate dispersant application significantly decreased hydrocarbon potency and identified metabolites may be bio-indicators of hydrocarbon stress from hydrocarbon exposure. © 2010 Elsevier Inc.

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