The significance of the analytic mean platelet volume determination in patients with the ischemic heart disease [Význam analytického stanovení středního objemu trombocytů (mean platelet volume - MPV) u nemocných s ischemickou chorobou srdeční]
Bulikova B.,Lekarska Fakulta MU Brno |
Krivan L.,Interni Kardiologicka Klinika FN |
Kala P.,Interni Kardiologicka Klinika FN |
Bulikova A.,Oddeleni Klinicke Hematologie FN |
And 2 more authors.
Intervencni a Akutni Kardiologie | Year: 2014
Objective: To explore the value of routine mean platelet volume (MPV) determination in patients with the acute coronary syndrome. Methods: We compared MPV in 333 persons divided into two groups. In the first group, there were patients hospitalized with an acute coronary syndrome (myocardial infarction or unstable angina pectoris). Second group was represented by patients with stable angina pectoris and healthy blood donors. Analyzers Cell Dyn Saphire and XL 5000 were used to determine MPV. Results: We proved statistically significant difference in the MPV value between patient with ACS and the group of healthy donors and patient with stable angina pectoris. We defined MPV cut-off value for high risk of the acute coronary syndrome 9,86 fl with sensitivity of 31,6% and specificity of 89%. Conclusion: The MPV may be useful for diagnosis, therapeutic decision and also prognosis of the acute coronary syndrome.