West Nyack, NY, United States
West Nyack, NY, United States

Nyack College is a private, evangelical, liberal arts college affiliated with the Christian and Missionary Alliance and home to the Alliance Theological Seminary, one of the denomination's seminaries. The main campus is located in Nyack, New York, United States. Branch campuses exist in Manhattan and Albany, as well as Puerto Rico, and Washington, D.C. Wikipedia.


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Huster M.E.,Nyack College
Physics Teacher | Year: 2011

While designing an optics lab for a conceptual physics course, I came across a "box theater" activity.1 The box theater is a pinhole camera obscura made from a box that students put over their heads and shoulders. I use the activity as a capstone experience to explain optical systems. (Classroom demonstrations of the camera obscura have been described by others.2) First, the students build and experiment with a camera obscura made from a plastic cup and a convex lens with a focal length of 7.5 cm, and then "wear" the box theater. The difficulty with the box theater is the dimness of the image. A cloth drape has to be hung from the bottom of the box around the shoulders of the students to prevent light leakage, and the students have to wait a few minutes for their eyes to adjust to the darkness.


PubMed | Southern Connecticut State University, University of North Texas, Bucknell University, Washington State University and 21 more.
Type: | Journal: Nature microbiology | Year: 2017

Temperate phages are common, and prophages are abundant residents of sequenced bacterial genomes. Mycobacteriophages are viruses that infect mycobacterial hosts including Mycobacterium tuberculosis and Mycobacterium smegmatis, encompass substantial genetic diversity and are commonly temperate. Characterization of ten Cluster N temperate mycobacteriophages revealed at least five distinct prophage-expressed viral defence systems that interfere with the infection of lytic and temperate phages that are either closely related (homotypic defence) or unrelated (heterotypic defence) to the prophage. Target specificity is unpredictable, ranging from a single target phage to one-third of those tested. The defence systems include a single-subunit restriction system, a heterotypic exclusion system and a predicted (p)ppGpp synthetase, which blocks lytic phage growth, promotes bacterial survival and enables efficient lysogeny. The predicted (p)ppGpp synthetase coded by the Phrann prophage defends against phage Tweety infection, but Tweety codes for a tetrapeptide repeat protein, gp54, which acts as a highly effective counter-defence system. Prophage-mediated viral defence offers an efficient mechanism for bacterial success in host-virus dynamics, and counter-defence promotes phage co-evolution.


Stewart P.E.,Montclair State University | Ames G.P.,Nyack College
Journal of Child and Adolescent Trauma | Year: 2014

Hurricane Katrina created a variety of issues that tested the resilience of families and children who were forced to relocate. This article describes the use of culturally affirming, thematically appropriate bibliotherapy as part of a long-term program to assist a group of elementary school aged African-American children cope with feelings of anxiety, displacement, and loss. This intervention provided a medium through which the participants could explore issues of isolation and the loss of their homes, family structures and a sense of security, while also providing academic and social supports. © 2014, Springer International Publishing.


News Article | February 15, 2017
Site: www.prweb.com

The Community for Accredited Online Schools, a leading resource provider for higher education information, has ranked the best schools with online programs in the state of New York for 2017. More than 70 schools were ranked overall, with Columbia University, New York University, Cornell University, Syracuse University and University at Buffalo coming in as the top four-year schools. Among two-year schools, Monroe Community College, Niagara County Community College, Hudson Valley Community College, Genesee Community College and Tompkins Cortland Community College earned top spots. “College-bound students have many options for post-secondary education in New York state, but they don’t necessarily need to travel to a campus to be successful,” said Doug Jones, CEO and founder of AccreditedSchoolsOnline.org. “The schools on this list are strong examples of what today’s online learning is all about: providing quality education to enhance student success outside of a traditional classroom environment.” Schools on the Best Online Schools list must meet specific base requirements to be included: each must be institutionally accredited and be classified as public or private not-for-profit. Each college was also scored based on additional criteria that includes cost and financial aid, variety of program offerings, student-teacher ratios, graduation rates, employment services and more. For more details on where each school falls in the rankings and the data and methodology used to determine the lists, visit: New York’s Best Online Four-Year Schools for 2017 include the following: Adelphi University Canisius College Clarkson University Columbia University in the City of New York Concordia College-New York Cornell University CUNY Graduate School and University Center CUNY John Jay College of Criminal Justice Dominican College of Blauvelt D'Youville College Fordham University Hofstra University Ithaca College Jewish Theological Seminary of America Keuka College LIU Post Marist College Medaille College Mercy College Metropolitan College of New York Mount Saint Mary College New York Institute of Technology New York University Niagara University Nyack College Pace University-New York Roberts Wesleyan College Rochester Institute of Technology Saint John Fisher College Saint Joseph's College-New York St. Bonaventure University St. John's University-New York St. Thomas Aquinas College Stony Brook University SUNY at Albany SUNY at Binghamton SUNY Buffalo State SUNY College at Brockport SUNY College at Oswego SUNY College at Plattsburgh SUNY College of Technology at Canton SUNY College of Technology at Delhi SUNY Empire State College SUNY Institute of Technology at Utica-Rome SUNY Maritime College SUNY Oneonta Syracuse University The College of Saint Rose The New School The Sage Colleges New York’s Best Two Year Online Schools for 2017 include the following: Bramson ORT College Cayuga Community College Corning Community College CUNY Borough of Manhattan Community College Finger Lakes Community College Fulton-Montgomery Community College Genesee Community College Herkimer College Hostos Community College Hudson Valley Community College Jamestown Community College Jefferson Community College Mohawk Valley Community College Monroe Community College Niagara County Community College North Country Community College Suffolk County Community College SUNY Broome Community College SUNY Orange SUNY Ulster SUNY Westchester Community College Tompkins Cortland Community College ### About Us: AccreditedSchoolsOnline.org was founded in 2011 to provide students and parents with quality data and information about pursuing an affordable, quality education that has been certified by an accrediting agency. Our community resource materials and tools span topics such as college accreditation, financial aid, opportunities available to veterans, people with disabilities, as well as online learning resources. We feature higher education institutions that have developed online learning programs that include highly trained faculty, new technology and resources, and online support services to help students achieve educational success.


Park P.J.,Nyack College | Chase I.,State University of New York at Stony Brook | Bell M.A.,State University of New York at Stony Brook
Current Zoology | Year: 2012

Threespine stickleback were used to examine phenotypic plasticity of telencephala in relation to inferred ecology. Fish from derived, allopatric, freshwater populations were sampled from three shallow, structurally complex lakes with benthic-foraging stickleback (benthics) and from three deep, structurally simple lakes with planktivores (limnetics). The telencephalon of specimens preserved immediately after capture (field-preserved), field-caught fish held in aquaria for 90 days (lab-held), and lab-bred fish from crosses and raised in aquaria were compared. Field-preserved sea-run (ancestral) stickleback were collected from two separate sites, and parents of lab-bred sea-run stickleback were collected from one of these sites. In field-preserved and lab-held fish, the telencephala of limnetics exhibited triangular dorsal shape, while those of benthics and sea-run fish had rounder shapes. No such pattern was detected in lab-bred fish. Within each treatment type, benthics had larger relative telencephalon sizes, using overall brain size as the covariate, than limnetics. Among field-preserved samples, sea-run fish had smaller telencephalon sizes than lake fish. Intra-population analyses of lake samples showed that field-preserved fish consistently had larger relative telencephalon sizes than lab-bred fish. The opposite was true of the sea-run population. In a separate study using one benthic population and one limnetic population, samples were preserved in the field immediately or held in the lab for 30, 60, and 90 days before they were sacrificed. In both populations, the telencephalon shapes of lab-held fish were similar to those of field-preserved fish but became progressively more like lab-bred ones over 90 days. In contrast, relative telencephalon size decreased dramatically by 30 days after which there was little change. In freshwater threespine stickleback, the telencephalon exhibits considerable phenotypic plasticity, which was probably present in the ancestor. © 2012 Current Zoology.


News Article | October 28, 2016
Site: www.prweb.com

A new list from leading higher education resource provider AffordableCollegesOnline.org has ranked the Best Online Colleges in New York state. Schools at the top of the list include Mercy College, CUNY Graduate School and University Center, SUNY College at Oswego, Metropolitan College of New York and SUNY College of Technology at Canton among four-year institutions; Genesee Community College, Niagara County College and Jefferson Community College among two-year institutions. In all, more than 30 colleges are being recognized for offering affordable, flexible online education options in the state. "There are over 1.2 million students enrolling in New York college and university programs annually,” said Dan Schuessler, CEO and Founder of AffordableCollegesOnline.org. "As more students apply to these schools, more also seek information on non-traditional and remote learning. We’ve analyzed more than a dozen data points to find which of New York’s colleges offer the best combination of quality and value when it comes to online education.” To make the Best Online Colleges in New York list, a school must meet specific qualification requirements. Only colleges and universities that are accredited are considered, and each must hold public or private not-for-profit standing. Cost and affordability minimums are also set; in-state tuition must fall under $5,000 annually for two-year institutions and under $25,000 annually for four-year institutions to qualify. Other ranking factors include financial aid and breadth of online program options. Find where each of New York’s Best Online Colleges ranks and learn more about the methodology used to compile each list at the link below: The following schools are recognized as the 2016-2017 Best Two-Year Online Colleges in New York: The following schools are recognized as the 2016-2017 Best Four-Year Online Colleges in New York: CUNY Graduate School and University Center D'Youville College Mercy College Metropolitan College of New York Nyack College Saint Joseph's College-New York Stony Brook University SUNY College at Oswego SUNY College at Plattsburgh SUNY College of Technology at Canton SUNY College of Technology at Delhi SUNY Empire State College SUNY Institute of Technology at Utica-Rome Trocaire College University at Buffalo Vaughn College of Aeronautics and Technology AffordableCollegesOnline.org began in 2011 to provide quality data and information about pursuing an affordable higher education. Our free community resource materials and tools span topics such as financial aid and college savings, opportunities for veterans and people with disabilities, and online learning resources. We feature higher education institutions that have developed online learning environments that include highly trained faculty, new technology and resources, and online support services to help students achieve educational and career success. We have been featured by nearly 1,100 postsecondary institutions and nearly 120 government organizations.


Akinyeke T.,New York University | Matsumura S.,New York University | Wang X.,New York University | Wu Y.,Dalian Medical University | And 5 more authors.
Carcinogenesis | Year: 2013

Prostate cancer (PCa) is the second leading cause of cancerrelated death in American men and many PCa patients develop skeletal metastasis. Current treatment modalities for metastatic PCa are mostly palliative with poor prognosis. Epidemiological studies indicated that patients receiving the diabetic drug metformin have lower PCa risk and better prognosis, suggesting that metformin may have antineoplastic effects. The mechanism by which metformin acts as chemopreventive agent to impede PCa initiation and progression is unknown. The amplification of c-MYC oncogene plays a key role in early prostate epithelia cell transformation and PCa growth. The purpose of this study is to investigate the effect of metformin on c-myc expression and PCa progression. Our results demonstrated that (i) in Hi-Myc mice that display murine prostate neoplasia and highly resemble the progression of human prostate tumors, metformin attenuated the development of prostate intraepithelial neoplasia (PIN, the precancerous lesion of prostate) and PCa lesions. (ii) Metformin reduced c-myc protein levels in vivo and in vitro. In Myc-CaP mouse PCa cells, metformin decreased c-myc protein levels by at least 50%. (iii) Metformin selectively inhibited the growth of PCa cells by stimulating cell cycle arrest and apoptosis without affecting the growth of normal prostatic epithelial cells (RWPE-1). (iv) Reduced PIN formation by metformin was associated with reduced levels of androgen receptor and proliferation marker Ki-67 in Hi-Myc mouse prostate glands. Our novel findings suggest that by downregulating c-myc, metformin can act as a chemopreventive agent to restrict prostatic neoplasia initiation and transformation. © The Author 2013. Published by Oxford University Press.


Yan W.,Nyack College | Li X.,New York University
Frontiers of Medicine in China | Year: 2013

Diabetes mellitus is an enormous menace to public health globally. This chronic disease of metabolism will adversely affect the skeleton if not controlled. Both type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) are associated with an increased risk of osteoporosis and fragility fractures. Bone mineral density is reduced in T1DM, whereas patients with T2DM have normal or slightly higher bone density, suggesting impaired bone quality is involved. Detrimental effects of T1DM on the skeleton are more severe than T2DM, probably because of the lack of osteo-anabolic effects of insulin and other pancreatic hormones. In both T1DM and T2DM, low bone quality could be caused by various means, including but not limited to hyperglycemia, accumulation of advanced glycosylation end products (AGEs), decreased serum levels of osteocalcin and parathyroid hormone. Risk for osteoarthritis is also elevated in diabetic population. How diabetes accelerates the deterioration of cartilage remains largely unknown. Hyperglycemia and glucose derived AGEs could contribute to the development of osteoarthritis. Moreover, it is recognized that oral antidiabetic medicines affect bone metabolism and turnover as well. Insulin is shown to have anabolic effects on bone and hyperinsulinemia may help to explain the slightly higher bone density in patients with T2DM. Thiazolidinediones can promote bone loss and osteoporotic fractures by suppressing osteoblastogenesis and enhancing osteoclastogenesis. Metformin favors bone formation by stimulating osteoblast differentiation and protecting them against diabetic conditions such as hyperglycemia. Better knowledge of how diabetic conditions and its treatments influence skeletal tissues is in great need in view of the growing and aging population of patients with diabetes mellitus. © 2013 Higher Education Press and Springer-Verlag Berlin Heidelberg.


Background: Spatial learning is the ability to learn and use features in space to navigate within an environment. In fishes, it is associated with residence in structurally complex habitat, but very little is known about its ancestral condition in adaptive radiations. Goal: To investigate the relationship between foraging mode and spatial learning in derived populations of a well-studied evolutionary model fish species, and to test the importance of experience on spatial learning in an ancestral analogue of this species. Organism: Threespine stickleback (Gasterosteus aculeatus) occur as sea-run (ancestral) and divergent freshwater (derived) forms. Freshwater populations occupy an ecological continuum, with benthic stickleback at one extreme, residing and foraging in shallow, structurally complex lakes, and limnetics at the other, living and feeding in the open water of deep lakes that lack structure. Methods: I used a T-maze to measure spatial learning. In Experiment 1, I compared five benthic and five limnetic field-caught stickleback populations to explore ecological divergence of spatial learning. In Experiment 2, I used a sea-run population to infer the ancestral condition of spatial learning; I studied laboratory-reared sea-run fish raised in spatially complex or simple aquaria because adequate samples of field-caught sea-run adults proved difficult to attain. Results: In Experiment 1, benthics exhibited better spatial learning than limnetics. These differences were independent of differences in boldness, exploratory behaviour, activity level, or other performance variables that are independent of spatial learning. In Experiment 2, no differences were detected between rearing treatments, but a number of fish from either group still solved the maze, indicating that even fish reared in spatially simple conditions were capable of spatial learning. However, the relative contributions of inheritance and experience remain unclear. © 2013 Peter J. Park.


Kaluka D.,Yeshiva University | Kaluka D.,Nyack College | Batabyal D.,University of California at Irvine | Chiang B.-Y.,Yeshiva University | And 2 more authors.
Biochemistry | Year: 2015

Progesterone receptor membrane component 1 (PGRMC1) is a 25 kDa protein with an N-terminal transmembrane domain and a putative C-terminal cytochrome b5 domain. Heme-binding activity of PGRMC1 has been shown in various homologues of PGRMC1. Although the general definition of PGRMC1 is as a progesterone receptor, progesterone-binding activity has not been directly demonstrated in any of the purified PGRMC1 proteins fully loaded with heme. Here, we show that the human homologue of PGRMC1 (hPGRMC1) binds heme in a five-coordinate (5C) high-spin (HS) configuration, with an axial tyrosinate ligand, likely Y95. The negatively charged tyrosinate ligand leads to a relatively low redox potential of approximately -331 mV. The Y95C or Y95F mutation dramatically reduces the ability of the protein to bind heme, supporting the assignment of the axial heme ligand to Y95. On the other hand, the Y95H mutation retains ∼90% of the heme-binding activity. The heme in Y95H is also 5CHS, but it has a hydroxide axial ligand, conceivably stabilized by the engineered-in H95 via an H-bond; CO binding to the distal ligand-binding site leads to an exchange of the axial ligand to a histidine, possibly H95. We show that progesterone binds to hPGRMC1 and introduces spectral changes that manifest conformational changes to the heme. Our data offer the first direct evidence supporting progesterone-binding activity of PGRMC1. © 2015 American Chemical Society.

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