NutraSource

Clarksville, MD, United States

NutraSource

Clarksville, MD, United States
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Guerin-Deremaux L.,ROQUETTE Freres | Pochat M.,ROQUETTE Freres | Reifer C.,SPRIM Advanced Life science | Wils D.,ROQUETTE Freres | And 2 more authors.
Nutrition Research | Year: 2011

Strong evidence supports the ability of dietary fibers to improve satiety. However, large variations in the physical and chemical characteristics of dietary fiber modulate the physiologic responses. We hypothesized that a nonviscous soluble dietary fiber may influence satiety. This randomized, double-blind, placebo-controlled clinical study in 100 overweight healthy adults in China investigated the effect of different dosages of dietary supplementation with a dextrin, NUTRIOSE (ROQUETTE frères, Lestrem, France), on short-term satiety over time. Subjects were randomized by body mass index and energy intake and then assigned to receive either placebo or 8, 14, 18, or 24 g/d of NUTRIOSE mixed with orange juice (n = 20 volunteers per group). On days -2, 0, 2, 5, 7, 14, and 21, short-term satiety was evaluated with a visual analog scale, and hunger feeling status was assessed with Likert scale. NUTRIOSE exhibits a progressive and significant impact on short-term satiety, which is time and dosage correlated. Some statistical differences appear for the group 8 g/d from day 5, and from day 0 for the groups 14, 18, and 24 g/d. The hunger feeling status decreases significantly from day 5 to the end of the evaluation for the group 24 g and from day 7 for the groups 14 and 18 g. By day 5, the group 24 g showed significantly longer time to hunger between meals compared with placebo. These results suggest that dietary supplementation with a soluble fiber can decrease hunger feeling and increase short-term satiety over time when added to a beverage from 8 to 24 g/d with time- and dose-responses relationship. © 2011 Elsevier Inc.


Oneil C.E.,Louisiana State University | Nicklas T.A.,Baylor College of Medicine | Zanovec M.,Louisiana State University | Cho S.S.,NutraSource | Kleinman R.,Harvard University
Public Health Nutrition | Year: 2011

Objective: To examine the association of consumption of whole grains (WG) with diet quality and nutrient intake in children and adolescents.Design: Secondary analysis of cross-sectional data.Setting: The 1999-2004 National Health and Nutrition Examination Survey.Subjects: Children aged 2-5 years (n 2278) and 6-12 years (n 3868) and adolescents aged 13-18 years (n 4931). The participants were divided into four WG consumption groups: ≥0 to <06, ≥0.6 to <1.5, ≥1.5 to <3.0 and ≥3.0 servings/d. Nutrient intake and diet quality, using the Healthy Eating Index (HEI)-2005, were determined for each group from a single 24 h dietary recall.Results: The mean number of servings of WG consumed was 045, 059 and 063 for children/adolescents at the age of 2-5, 6-12 and 13-18 years, respectively. In all groups, HEI and intakes of energy, fibre, vitamin B6, folate, magnesium, phosphorus and iron were significantly higher in those consuming 30 servings of WG/d; intakes of protein, total fat, SFA and MUFA and cholesterol levels were lower. Intakes of PUFA (6-12 years), vitamins B1 (2-5 and 13-18 years), B2 (13-18 years), A (2-5 and 13-18 years) and E (13-18 years) were higher in those groups consuming ≥3.0 servings of WG/d; intakes of added sugars (2-5 years), vitamin C (2-5 and 6-12 years), potassium and sodium (6-12 years) were lower.Conclusions: Overall consumption of WG was low. Children and adolescents who consumed the most servings of WG had better diet quality and nutrient intake. © 2010 The Authors.


O'Neil C.E.,Louisiana State University | Zanovec M.,Louisiana State University | Cho S.S.,NutraSource | Nicklas T.A.,Baylor College of Medicine
Nutrition Research | Year: 2010

This study examined the association of whole grain consumption with body weight measures and prevalence of overweight/obesity in a recent, nationally representative sample of adults. A secondary analysis of 1999-2004 National Health and Nutrition Examination Survey (NHANES) data was conducted using adults 19 to 50 years of age (y) (n = 7,039) and 51+ y (n = 6,237). Participants were categorized by whole grain consumption: ≥ 0 to <0.6, ≥ 0.6 to <1.5, ≥ 1.5 to <3.0, and ≥ 3.0 servings/day. Main outcome measures included body mass index (BMI), waist circumference (WC), and prevalence of overweight/obesity. Sample weights were applied and the number and percentages of adults in whole grain consumption groups were determined. Least-square means and standard errors were calculated for body weight measures. Two regression models were developed and compared. Model 1 covariates included age, gender, ethnicity, and total energy intake; Model 2 was extended to include cereal fiber. Trend analysis was conducted to test for differences between least-square means. Significance was set at P ≤ .05. Adults 19-50 and 51+ y consumed a mean of 0.63 and 0.77 servings of whole grains/day, respectively. A significant trend was observed in both age groups for increased consumption of whole grains with lower BMI, WC, and percentage overweight/obese (Model 1); however, a significant trend was not observed when cereal fiber was added as a covariate (Model 2). Results confirm overall whole grain intake well below recommendations, and adults who consumed the most servings of whole grains had lower body weight measures. Results also suggest that fiber in whole grain foods may mediate associations with weight measures in adults. Intake of whole grain foods should be encouraged by health professionals. © 2010 Elsevier Inc.


Cho S.S.,NutraSource | Qi L.,Harvard University | Fahey Jr G.C.,Urbana University | Klurfeld D.M.,U.S. Department of Agriculture
American Journal of Clinical Nutrition | Year: 2013

Background: Studies of whole grain and chronic disease have often included bran-enriched foods and other ingredients that do not meet the current definition of whole grains. Therefore, we assessed the literature to test whether whole grains alone had benefits on these diseases. Objective: The objective was to assess the contribution of bran or cereal fiber on the impact of whole grains on the risk of type 2 diabetes (T2D), obesity and body weight measures, and cardiovascular disease (CVD) in human studies as the basis for establishing an American Society for Nutrition (ASN) position on this subject. Design: We performed a comprehensive PubMed search of human studies published from 1965 to December 2010. Results: Most whole-grain studies included mixtures of whole grains and foods with $25% bran. Prospective studies consistently showed a reduced risk of T2D with high intakes of cereal fiber or mixtures of whole grains and bran. For body weight, a limited number of prospective studies on cereal fiber and whole grains reported small but significant reductions in weight gain. For CVD, studies found reduced risk with high intakes of cereal fiber or mixtures of whole grains and bran. Conclusions: The ASN position, based on the current state of the science, is that consumption of foods rich in cereal fiber or mixtures of whole grains and bran is modestly associated with a reduced risk of obesity, T2D, and CVD. The data for whole grains alone are limited primarily because of varying definitions among epidemiologic studies of what, and how much, was included in that food category. © 2013 American Society for Nutrition.


Lee A.W.,NutraSource | Cho S.S.,NutraSource
Nutrition Journal | Year: 2015

The objective of this study was to estimate the independent associations between intake of phosphorus (P) and bone health parameters such as bone mineral content (BMC) and bone mineral density (BMD). It provides odds ratio (OR) of osteoporosis with quartiles of P intake adjusted for covariates (i.e., age, gender, BMI, and consumption of calcium (Ca), protein, total dairy foods, and vitamin D as well as intakes of supplemental Ca, vitamin D, and multivitamins/minerals). Data came from males and females aged 13-99 years who participated in the 2005-2010 National Health and Nutrition Examination Survey (NHANES). Analyses showed that higher P intake was associated with higher Ca intake, and that dietary Ca:P ratios (0.51-0.62, with a mean of 0.60 for adults) were adequate in all age/gender groups. High intake of P was positively associated with BMC in female teenagers (Q4 vs. Q1: BMC, 30.9 ± 1.1 vs. 29.0 ± 0.5 g, P = 0.001). It was also positively associated with BMC and BMD as well as reduced risk of osteoporosis in adults >20 years of age (Q4 vs. Q1: OR of osteoporosis, 0.55; 95% confidence interval [CI], 0.39- 0.79; P = 0.001; BMC, 37.5 ± 0.4 vs. 36.70 ± 0.3 g, P < 0.01; BMD, 0.986 ± 0.004 vs. 0.966 ± 0.005 g/cm2, P < 0.05). The data suggest that high intake of P has no adverse effect on bone metabolism in populations with adequate Ca intake, and that it is also associated with positive bone parameters in some age/gender groups. © 2015 Lee and Cho.; licensee BioMed Central.


Xu M.,Harvard University | Huang T.,Harvard University | Lee A.W.,NutraSource | Qi L.,Harvard University | Cho S.,NutraSource
Journal of the American College of Nutrition | Year: 2016

Background: Intakes of ready-to-eat cereal (RTEC) have been inversely associated with risk factors of chronic diseases such as cardiovascular disease (CVD), type 2 diabetes, and certain cancers; however, their relations with total and cause-specific mortality remain unclear. Objective: To prospectively assess the associations of RTEC intakes with all causes and disease-specific mortality risk. Design: The study included 367,442 participants from the prospective National Institutes of Health (NIH)–AARP Diet and Health Study. Intakes of RTEC were assessed at baseline. Results: Over an average of 14 years of follow-up, 46,067 deaths were documented. Consumption of RTEC was significantly associated with reduced risk of mortality from all-cause mortality and death from CVD, diabetes, all cancer, and digestive cancer (all p for trend < 0.05). In multivariate models, compared to nonconsumers of RTEC, those in the highest intake of RTEC had a 15% lower risk of all-cause mortality and 10%–30% lower risk of disease-specific mortality. Within RTEC consumers, total fiber intakes were associated with reduced risk of mortality from all-cause mortality and deaths from CVD, all cancer, digestive cancer, and respiratory disease (all p for trend < 0.005). Conclusions: Consumption of RTEC was associated with reduced risk of all-cause mortality and mortality from specific diseases such as CVD, diabetes, and cancer. This association may be mediated via greater fiber intake. © 2015 American College of Nutrition Published by Taylor & Francis Group, LLC.


Gao Y.,Yantai University | Shen J.,Yantai University | Yin J.,Yantai University | Li C.,Yantai University | And 2 more authors.
Food and Chemical Toxicology | Year: 2013

We conducted a 90-day feeding study to investigate subchronic toxicity of rice hull fiber. Sprague Dawley rats were randomly divided into four groups; each received a diet containing 0%, 2.5%, 3.75% and 5.0% (w/w) rice hull fiber for 90. days. Clinical observations were carried out daily, with weekly measurements of body weight and food consumption. We performed ophthalmic and histological examinations at termination. Blood and urine samples were collected to measure hematology and clinical chemistry parameters. No mortality, ophthalmic abnormalities, or adverse treatment-related effects were seen during clinical observations, hematological tests, or analyses of urine. Macroscopic or microscopic examinations of organs revealed no treatment related abnormalities. The only treatment related significant changes were reduced concentrations of fasting blood glucose (up to 17.6%) and cholesterol (up to 22.0%), typical benefits of dietary fiber, in males treated with 3.75 and 5% rice hull fiber. The no-observed-adverse-effect-level (NOAEL) for rice hull fiber was 5.0% for both genders (females, 3.80. g/kg body weight/day; males, 4.11. g/kg body weight/day). © 2012 Elsevier Ltd.


PubMed | NutraSource
Type: | Journal: Nutrition journal | Year: 2015

The objective of this study was to estimate the independent associations between intake of phosphorus (P) and bone health parameters such as bone mineral content (BMC) and bone mineral density (BMD). It provides odds ratio (OR) of osteoporosis with quartiles of P intake adjusted for covariates (i.e., age, gender, BMI, and consumption of calcium (Ca), protein, total dairy foods, and vitamin D as well as intakes of supplemental Ca, vitamin D, and multivitamins/minerals). Data came from males and females aged 13-99 years who participated in the 2005-2010 National Health and Nutrition Examination Survey (NHANES). Analyses showed that higher P intake was associated with higher Ca intake, and that dietary Ca:P ratios (0.51-0.62, with a mean of 0.60 for adults) were adequate in all age/gender groups. High intake of P was positively associated with BMC in female teenagers (Q4 vs. Q1: BMC, 30.9 1.1 vs. 29.0 0.5 g, P = 0.001). It was also positively associated with BMC and BMD as well as reduced risk of osteoporosis in adults >20 years of age (Q4 vs. Q1: OR of osteoporosis, 0.55; 95% confidence interval [CI], 0.39- 0.79; P = 0.001; BMC, 37.5 0.4 vs. 36.70 0.3 g, P < 0.01; BMD, 0.986 0.004 vs. 0.966 0.005 g/cm(2), P < 0.05). The data suggest that high intake of P has no adverse effect on bone metabolism in populations with adequate Ca intake, and that it is also associated with positive bone parameters in some age/gender groups.

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