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Daegu, South Korea

Lee J.Y.,Kyungpook National University | Kang K.M.,Kyungpook National University | Shin J.P.,Kyungpook National University | Kim I.T.,Kyungpook National University | And 2 more authors.
British Journal of Ophthalmology | Year: 2013

Aim: To evaluate the effects and stability of AcrySof toric intraocular lens (IOL) implantation in patients who had combined microincision vitrectomy surgery (MIVS) and phacoemulsification for vitreoretinal diseases and cataract with corneal astigmatism. Methods: A retrospective comparative study with 20 patients (20 eyes) who had combined 23-gauge MIVS and phacoemulsification with regular corneal astigmatism (>1.00 dioptres) was done. 10 eyes had toric IOL and 10 eyes had non-toric IOL implantation. The main outcome measures were uncorrected visual acuity (UCVA), refractive cylinder and toric IOL axis rotation at postoperative months 1, 6, 12, 18 and 24. Results: The mean UCVA of toric IOL was better than non-toric IOL at each postoperative period (p=0.019, 0.001, 0.007, 0.004 and 0.001, respectively). The mean absolute residual refractive cylinder of toric IOL was less than non-toric IOL at each postoperative period (p=0.001, <0.001, <0.001, <0.001 and <0.001, respectively). At month 24, the mean toric IOL axis rotation was 3.3±2.1°, which was within 5° in 80% and within 10° in 100%. Conclusions: Toric IOL implantation could be an effective method of correcting corneal astigmatism in patients who have vitreoretinal diseases and cataract. The toric IOL showed good rotational stability, even in vitrectomised eyes for 24 months. Source


Chang M.,Korea University | Lee T.S.,Nune Eye Hospital | Yoo E.,Korea University | Baek S.,Korea University
British Journal of Ophthalmology | Year: 2011

Purpose: To evaluate the long-term efficacy of a new surgical technique for the correction of lower lid epiblepharon using thermal contraction of the tarsus and lower lid retractor without lash rotating sutures. Methods: A retrospective study was conducted on 112 eyes of 56 patients who underwent surgical correction of lower lid epiblepharon with a modified Hotz operation (group A) or a new procedure (group B). The new technique requires that thermal contraction using bipolar cautery was applied to the inferior tarsus including the pretarsal orbicularis oculi muscle and lower lid retractor to create lash rotation without additional rotating sutures. The authors compared the results from these two techniques. Results: 44 eyes of 22 patients (11 boys and 11 girls) were included in group A, the average age was 5.5 years (±2.2), follow-up periods were 56.9 months (±7.7). Undercorrections developed in four eyes (9.1%), and epiblepharon recurred in seven eyes (15.9%). In group B, 68 eyes of 34 (20 male and 14 female) patients were included, with an average age of 5.1 years (±2.5), and a mean follow-up period of 39.7 months (±9.5). Epiblepharon recurred in three eyes (4.4%), and no patients were undercorrected. The recurrence and undercorrection rates were significantly lower in group B (p=0.022 and p=0.047). Conclusion: The new surgical technique for the correction of lower lid epiblepharon using thermal contraction of the tarsus and lower lid retractor without lash rotating sutures was very useful and effective for the correction of epiblepharon, with good cosmetic results. Source


Park D.H.,Kyungpook National University | Shin J.P.,Kyungpook National University | Kim S.Y.,Nune Eye Hospital
Eye | Year: 2011

Aim: To compare AcrySof toric intraocular lens (IOL) and non-toric IOL in patients who had combined 23-gauge microincisional vitrectomy surgery (MIVS) and phacoemulsification for vitreoretinal diseases and cataract with pre-existing corneal astigmatism. Methods: This is a prospective comparative study comprised of 30 patients (30 eyes) who had combined 23-gauge MIVS and phacoemulsification for vitreoretinal diseases and cataract with pre-existing regular corneal astigmatism greater than 1 diopters (D). In all, 15 eyes had AcrySof toric IOL (Alcon Laboratories) and 15 eyes had non-toric IOL (Akreos AO MI60; Bausch Lomb) implantation. Main outcome measures were uncorrected visual acuity (UCVA), refractive cylinder, surgically induced astigmatism (SIA), and IOL misalignment during 6 months. Results: The mean UCVA of the toric IOL group was better than the non-toric IOL group at postoperative months 1, 3, and 6 (P<0.001, respectively). The mean absolute residual refractive cylinder of the toric IOL group at postoperative week 1, and months 1, 3, and 6 was less than the non-toric IOL group (P=0.008, <0.001, <0.001, and <0.001, respectively). There was no difference in the mean SIA between the two groups (P>0.05, respectively). The mean toric IOL axis rotation was 3.52±2.75°, which was within 5° in 66.7% of the toric IOL group and within 10° in 100%. Conclusions: Combined 23-gauge MIVS and phacoemulsification with AcrySof toric IOL implantation is an effective method of correcting vitreoretinal diseases and cataract and pre-existing corneal astigmatism, and the toric IOL showed good rotational stability, even in vitrectomized eyes for 6 months. © 2011 Macmillan Publishers Limited All rights reserved. Source


Cho Y.A.,Nune Eye Hospital | Cho Y.A.,Korea University | Ryu W.Y.,Dong - A University
British Journal of Ophthalmology | Year: 2015

Background: To determine the long-term changes in refractive error and ocular alignment in patients with accommodative esotropia (AET) who were able to discontinue wearing hyperopic glasses because of emmetropisation. Methods: Forty-seven patients with refractive AET who achieved emmetropisation and orthotropia without hyperopic glasses and were followed up for at least 3 years were enrolled. All of the patients had been prescribed the weakest possible glasses for best corrected vision. Refractive error and ocular alignment were analysed after the cessation of hyperopic glasses use. Results: The mean length of follow-up was 5.7±3.21 years after successful weaning from hyperoptic glasses. The mean spherical equivalent (SE) of the refractive error was -1.01±1.53 dioptres (D), and the mean esotropia (ET) was 1.0±8.70 Δ at the final visit. Myopia developed in 55.3% of all patients. The mean myopic progression rate per year was -0.19±0.23 D/year. Forty-one patients (87.2%) showed orthotropia; in addition, three of the patients (6.4%) developed ET, and three (6.4%) developed exotropia (XT). The six patients who had ET or XT all showed myopia. Two of the three patients who developed ET underwent surgery. Both patients initially had a low degree of hyperopia and a high ratio of accommodative convergence to accommodation (AC/A). The initial hyperopia correlated with the SE refractive error at the final follow-up (p<0.001). Conclusions: When emmetropisation occurs early in patients with AET, it is necessary to note the development of myopia and the deterioration of ocular alignment. © 2015, BMJ Publishing Group. All rights reserved. Source


Kim K.M.,Nune Eye Hospital | Shin Y.-T.,Kyungpook National University | Kim H.K.,Kyungpook National University
Japanese Journal of Ophthalmology | Year: 2012

Purpose: Platelet-rich plasma (PRP) harbors high concentrations of growth factors related to the promotion of wound healing. We evaluated the efficacy of PRP eyedrops in the treatment of persistent epithelial defects (PEDs). Methods: Autologous PRP and autologous serum (AS) were prepared from whole blood. The concentrations of transforming growth factor (TGF)-β1, TGF-β2, epidermal growth factor (EGF), vitamin A and fibronectin in the PRP and AS were analyzed and compared. The corneal epithelial healing efficacy of PRP was compared with that of AS in patients with PED induced by post-infectious inflammation. Results: The concentrations of TGF-β1, TGF-β2, EGF, vitamin A and fibronectin in the PRP and AS were not statistically different. However, the concentrations of EGF in the PRP were significantly greater than in the AS. AS was used in 17 and PRP in 11 eyes of 28 patients. The healing rates of the corneal epithelia of the PRP-treated eyes were significantly higher than those treated with AS. Conclusions: The PRP was effective in the treatment of PEDs. This may be attributable to its high concentration of platelet-contained growth factors, most notably EGF. PRP could be an effective, novel treatment option for chronic ocular surface disease. © Japanese Ophthalmological Society 2012. Source

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