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Takeshita Y.,Nippon Telegraph and Telephone | Sawada T.,Nippon Telegraph and Telephone | Handa T.,Nippon Telegraph and Telephone | Watanuki Y.,Nippon Telegraph and Telephone | Kudo T.,NTT East Corporation
Progress in Organic Coatings | Year: 2012

Properties such as the specular gloss, adhesive strength, viscoelasticity, and impact resistance of thermoplastic polyester powder coating film were studied as a function of air-cooling time. Thermoplastic polyester resin is known for the fact that the heating condition has an effect on the degree of crystallinity. We focused on the relationship between the air-cooling time employed in the film preparation process and the degree of crystallinity. The test pieces were dipped into a fluidized polyester powder vessel, and then cooled in air to form the film. We refer to this cooling time in air as the "air-cooling time". It was found that the degree of crystallinity increased as the air-cooling time increased. As the degree of crystallinity increased, the specular gloss, adhesive strength, viscosity and impact resistance decreased. We therefore found that the improvement in film performance is related to the reduction in the air-cooling time. The importance of this phenomenon is considered in relation to the widespread use of thermoplastic polyester resin. Similar behavior is expected for other polyester powder coatings. © 2012 Published by Elsevier B.V. All rights reserved.

Fujimoto M.,Kanazawa University | Hamaguchi Y.,Kanazawa University | Kaji K.,Kanazawa University | Matsushita T.,Kanazawa University | And 19 more authors.
Arthritis and Rheumatism | Year: 2012

Objective To identify the 140-kd autoantigen recognized by anti-155/140 autoantibodies that are associated with adult cancer-associated dermatomyositis (DM) and juvenile DM and to determine the clinical relevance of anti-155/140 antibodies in a large cohort. Methods Sera from 456 DM patients were assessed for the presence of anti-155/140 antibodies by immunoprecipitation using K562 cell extracts as substrate. Using immunoprecipitation and Western blotting, we then examined whether anti-155/140-positive sera recognized transcription intermediary factor 1α (TIF-1α), TIF-1β, and TIF-1γ. The clinical associations of antigen reactivity were also evaluated. Results Anti-155/140-positive sera reacted with 140-kd TIF-1α in addition to 155-kd TIF-1γ. Among sera from 456 DM patients, 52 were reactive with both TIF-1α and TIF-1γ, while another 25 were reactive with TIF-1γ alone. Additionally, 7 were reactive with TIF-1β. Malignancy was more frequently found in adult patients with both anti-TIF-1α and anti-TIF-1γ antibodies than in those with anti-TIF-1γ antibodies alone (73% versus 50%; P < 0.05). In addition to juvenile DM patients and middle-aged and older DM patients with high percentages of malignancy, 8 "young adult" DM patients without malignancy had these autoantibodies. Conclusion Anti-155/140 antibodies target TIF-1 family proteins, TIF-1α and TIF-1β, in addition to TIF-1γ. Since TIF-1 proteins have significant roles in oncogenesis, these antibodies may be produced during misdirected antitumor immunity. © 2012 American College of Rheumatology.

Yoshioka N.,NTT East Corporation | Ishii H.,Nara Medical University | Tajima N.,Jikei University School of Medicine | Iwamoto Y.,Tokyo Women's Medical University
Current Medical Research and Opinion | Year: 2014

Objective: To better understand patient resistance to initiation of insulin therapy, this study examined the perception gap concerning initiation of insulin therapy between individuals with type 2 diabetes and their physicians by using data from the DAWN Japan study. Methods: The DAWN Japan study is a multi-center, questionnaire-based survey, conducted between 2004-2005. Patients recommended to start insulin therapy (n = 148) answered a questionnaire by rating degree of agreement with 16 statements concerning insulin therapy on a 5-point scale (1: strongly disagree to 5: strongly agree). Ratings of 1 and 2 were categorized as 'disagree' with a statement, and 3, 4, and 5 as 'agree'. Their attending physicians (n = 68) selected statements which could be associated with patient's concerns about insulin therapy. Results: Nearly all the patients agreed with the statements 'I don't want to inject myself for the rest of my life' (95%), and 'I don't want to be bothered with doing injections' (90%); fewer than half agreed with 'My friendships may suffer' (46%), and 'I don't understand why insulin is necessary for me' (45%). Estimation by the physicians and the actual perceptions patients reported differed significantly for 13 statements. Physicians seemed to particularly under-estimate the impact associated with social aspects of insulin use (e.g., 'I don't want to be different from others', 55% patients vs 7% physicians). On the contrary, the statement 'Injections are painful' was the only concern over-estimated by the physicians. Conclusions: It was demonstrated that differences in perceptions regarding insulin therapy exist between physicians and patients, particularly in terms of social impacts. The data, obtained in 2004, may not precisely reflect the present situation, but still represents a barrier to insulin therapy widely held by patients and physicians. These results suggest that appropriate understanding of patients' concerns about insulin therapy is important to encourage timely insulin initiation. © 2014 Informa UK Ltd.

Nishiyama H.,Tohoku University | Kudoh D.,Tohoku University | Kato N.,NTT East Corporation | Kadowaki N.,Japan National Institute of Information and Communications Technology
Proceedings of the IEEE | Year: 2011

While GEostationary Orbit (GEO) satellite systems provide us with a wide coverage area, their long delay serves as a significant constraint for real-time applications. On the other hand, Low Earth Orbit (LEO) satellite systems are best suited to delay sensitive applications. However, the coverage and mobility issues of LEO satellites lead to relatively high management costs. In this paper, we devise a new load balancing and quality of service (QoS) provisioning scheme to accommodate both real-time and non-real-time traffic based on a new congestion-prediction scheme. The effect of this new scheme is expected to improve the efficiency of the GEO/LEO hybrid satellite networks and the QoS satisfaction of end users. © 2011 IEEE.

Tanaka Y.O.,University of Tsukuba | Okada S.,University of Tsukuba | Yagi T.,University of Tsukuba | Yagi T.,Kinu Medical Association Hospital | And 5 more authors.
American Journal of Roentgenology | Year: 2010

OBJECTIVE. Although mural nodules are considered to be the most important hallmark in the recognition of ovarian cancers accompanied with endometriotic cysts, benign neoplasms and even inflammatory diseases can show similar MRI findings. We sought to clarify the MRI characteristics of malignancy accompanied with endometriotic cysts of the ovary. MATERIALS AND METHODS. Contrast-enhanced MRI was performed and endometriosis was pathologically confirmed in 49 patients with endometriotic cysts displaying mural nodules. Malignancy was pathologically diagnosed in 33 patients and benignity, in 16. Clinical data including patient age and MRI findings in terms of the size of the endometriotic cysts, number of loculi, presence of shading of the cysts, size of the mural nodules, signal intensity of the mural nodules on T1- and T2-weighted images, and contrast enhancement of the mural nodules were retrospectively reviewed. Statistical analysis of each parameter used the Mann-Whitney U test. RESULTS. The mean age of the patients and mean size of the endometriotic cysts were significantly higher in patients with a malignant condition than in those with a benign condition. Contrast enhancement of the mural nodules was observed in 97% of malignant and 44% of benign tumors. The size of the mural nodules was significantly larger in patients with a malignant condition than in those with a benign condition. Differences in size between the bilateral diseases, multilocularity, existence of shading, and the signal intensities of mural nodules were not significantly different between the malignant and benign conditions. CONCLUSION. Endometriotic cysts with enhanced mural nodules are not always complicated with malignancy. In elderly patients, the presence of large enhanced nodules on large endometriotic cysts is more likely to indicate malignancy. © American Roentgen Ray Society.

Kimura T.,NTT East Corporation | Morita A.,NTT East Corporation
Neurologia Medico-Chirurgica | Year: 2010

A 60-year-old woman presented with a rare unruptured aneurysm of duplication of the middle cerebral artery (DMCA) identified at examination for headache. Preoperative cerebral angiography revealed the DMCA and a small aneurysm at its origin. Surgical clipping was performed successfully via the transsylvian approach. DMCA aneurysms have a tendency to bleed even if small, but the anatomical configuration causes some technical difficulties.

Itoh N.,NTT East Corporation
Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica | Year: 2013

"Sex" is defined by several factors, such as chromosomes, gonads, and internal and external genitalia. Males basically have a Y chromosome and testes. The testis produces and secretes Mullerian inhibiting substance and testosterone. These two factors induce internal and external genitalia to develop into the male phenotype. The degree of sexual differentiation relates to the levels of Müllerian inhibiting substance and testosterone. The treatment strategy for patients with sexual differentiation should be decided based on the degree of abnormality of internal and external genitalia.

Takano Y.,Chiba Institute of Technology | Inoue A.,Chiba Institute of Technology | Kurosawa T.,Tokyo University of Science | Iwashita M.,Chiba Institute of Technology | Nishimatsu K.,NTT East Corporation
Proceedings - 9th IEEE/ACIS International Conference on Computer and Information Science, ICIS 2010 | Year: 2010

Service choice behavior of customers is becoming complicated and diversified in the mobile phone market. The aim of this paper is to analyze mobile carrier choice behavior and clarify the customer segments and their decision-making factors. We classify mobile phone customers into two groups: churning customers and stable customers. Customer segmentation is carried out based on survey data for each customer group in order to clarify the decision-making factors. We propose a new service choice modeling with regard to mobile carriers based on the customer segmentation results. © 2010 IEEE.

PubMed | NTT East Corporation, Niigata University, National Center for Global Health and Medicine, St Lukes International Hospital and 4 more.
Type: Journal Article | Journal: Journal of diabetes investigation | Year: 2016

The Standard Diabetes Manual has been developed by clinical researchers from multiple major institutions in Japan, such as the National Center for Global Health and Medicine, as a comprehensive disease management program, including collaboration between primary care physicians (PCPs) and specialist services. The present study evaluated the efficacy of the manual as a quality improvement strategy in diabetes care by PCPs.A total of 42 PCPs in eight domestic districts of the Japan Medical Association were allocated to either the intervention group or the control group in a cluster-randomized design. The PCPs in both groups were provided with a copy of the Diabetes Treatment Guide published by the Japan Diabetes Society, and the PCPs in the intervention group additionally received a copy of the manual and a 30-min relevant seminar at the inception of the intervention. The primary end-point was the adherence to the following performances as quality indicators: evaluation of retinopathy, and urinary albumin excretion measurements and serum creatinine measurements, as recommended by the Japan Medical Association.A total of 416 patients were enrolled by 36 PCPs. During the 1-year follow-up period, the proportion of PCPs who adhered to recommendation-concordant measurements of urinary albumin excretion was significantly higher in the intervention group than in the control group (adherence: 17.9% vs 5.3%, P = 0.016). The other parameters were not statistically different between the two groups.Implementation of The Standard Diabetes Manual potentially leads to an improved quality of diabetes management by PCPs.

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