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Agrawal V.,Nscb Government Medical College
Asian journal of endoscopic surgery | Year: 2012

Purulent pericarditis is an extremely rare complication of pneumococcal pneumonia in children that may result in to cardiac tamponade. While image-guided pericardiocentesis is the treatment of choice for such a condition, it may fail in the presence of thick pus; loculations and thoracoscopic pericardiotomy are useful procedures for such situations. Herein, we report such a case involving a 6-year-old boy who presented with purulent pneumococcal pericarditis that was managed with thoracoscopic pericardiotomy and who recovered well. Thoracoscopic pericardiotomy is a safe procedure that allows effective drainage under vision, pericardial biopsy for diagnosis, and a simultaneous opportunity to perform thoracoscopic pleural drainage. © 2012 Japan Society for Endoscopic Surgery, Asia Endosurgery Task Force and Blackwell Publishing Asia Pty Ltd.

Badkur P.,Nscb Government Medical College | Singh K.N.,Nscb Government Medical College | Singh K.N.,Advanced Colposcopy Center | Ghanghoriya V.,Nscb Government Medical College
Journal of Obstetrics and Gynecology of India | Year: 2016

Aims and Objectives: To study the colposcopic findings and prevalence of lower genital tract infections in HIV-positive women on anti-retroviral therapy. To find correlation between colposcopic finding, m RNA HPV and cytology of lower genital tract infections in HIV-positive women on anti-retroviral therapy. Materials and Methods: The present prospective observational study was conducted in the Department of Obstetrics and Gynaecology, Netaji Subhash Chandra Bose Medical College, Jabalpur, from 1 June 2013 to 31 October 2014. The data of the present study was recorded into computer and after proper validation, error checking, coding and decoding, the data was compiled and analysed using the SPSS Windows. Appropriate univariate and bivariate analysis were carried out using the Student’s t test and two-tailed Fisher exact test or Chi-square test for categorical variables. Results and Conclusion: The present study concludes that the prevalence of lower genital tract infections is 25.3 % in HIV-positive women on anti-retroviral therapy. It revealed that 35 HIV-positive women on anti-retroviral therapy who were screened for m HPV RNA test, one came out to be positive (i.e. 2.8 %); thus, it can be said that there is an increased clearance of oncogenic HPV types in HIV-positive women on anti-retroviral therapy. © 2016 Federation of Obstetric & Gynecological Societies of India

Agarwal P.,Nscb Government Medical College | Singh M.,Nscb Government Medical College | Sharma D.,Nscb Government Medical College
Indian Journal of Surgery | Year: 2015

There is little information available on the bacteriological contamination of Cheattle’s forceps during routine use and the effects of antiseptic solutions. This study was conducted to detect infection in various antiseptics and disinfections in-use used for keeping the Cheattle’s forceps in surgical wards. An aqueous solution of 0.5 and 1 % cetrimide/chlorhexidine, 2.4 % glutaraldehyde, 5 % povidone iodine, and 10 % chloroxylenol were compared using the normal saline as control. The samples from each bottle were sent for culture on the 3rd, 5th, and 7th day. All the culture reports were analyzed and statistically compared. A total of 2,160 samples were sent for culture from solutions including control over a period of 7 days. A total of 360 samples were sent for culture from each antiseptic solution. Out of 2,160 samples, 240 (11.11 %) were positive over a period of 7 days for contamination with microbial organisms. The most common organism isolated was Pseudomonas present in 140 samples followed by E. coli in 71 samples. S. aureus was present in seven samples, bacillus in ten samples, and Coaglase -ve Streptococcus and Klebsiella in six samples each. Number of positive culture consistently increased in normal saline and cetrimide/chlorhexidine, but povidone iodine, chloroxylenol, and glutaraldehyde did not show any positive culture on the 3rd day. Povidone iodine and glutaraldehyde showed positive culture on the 5th and 7th day, respectively., but they were statistically insignificant. On the 7th day, glutaraldehyde was the only solution which did not show any positive culture. We strongly recommend that the Cheattle’s forceps should be kept in a bottle containing glutaraldehyde or chloroxylenol. © 2014, Association of Surgeons of India.

Dubey A.K.,Sharda University | Raichandani O.M.,Nscb Government Medical College | Pandey S.P.,Nscb Government Medical College
International Journal of Pharma and Bio Sciences | Year: 2012

Background: Major Depressive Disorder (MDD) is a chronic illness with large contribution to disease burden worldwide.Duloxetine, a dual reuptake inhibitor of 5-HT and NE, is a second generation antidepressant, on which, to the best of our knowledge, there is no study in the Indian adult patients of MDD. There have been studies on duloxetine in MDD patients inother parts of the world, but there has not yet been a study comparing it with the old standard imipramine, a tricyclic acid antidepressant, still commonly used in the primary health care set up. Aims: In this study the efficacy of duloxetineinMDD was compared with that of imipramine. Settings and Design: Prospective observer blinded parallel group comparative study. Materials and Methods: Consenting adult patients (N=60) meeting DSM-IV criteria for MDD who completed six weeks of treatment with, either duloxetine (40 mg) or imipramine (150 mg), were compared for improvement with their base line disease severity, measured by scores on the Hamilton Depression (HAM-D) Rating Scale with 21 items and Clinical Global Impression (CGI) scale. The primary efficacy measure was mean change from baseline to endpoint on the HAM-D scale. Results: The totalchange in HAM-D score in imipramine group was -25.53 (±7.82) exhibiting an improvement of 67.54% and the total change in HAM-D score in duloxetine group was -20.27(±7.04) showing an improvement of 60.45%. Imipramine showed a slightly greater reduction of HAM-D scores as compared to duloxetine, which was statistically significant, but there was no statisticallysignificant difference between the response rates (80% vs 73.3%) and remission rates (30% vs 26.7%) for imipramine and duloxetine, respectively, at six weeks. Conclusion: The efficacy of duloxetine and imipramine is comparable in MDD with no significant difference in response and remission rates at six weeks.

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