Nowy Sacz School of Business - National-Louis University

www.wsb-nlu.edu.pl
Nowy Sacz, Poland
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Jasienska G.,Jagiellonian University | Ellison P.T.,Harvard University | Galbarczyk A.,Jagiellonian University | Jasienski M.,Nowy Sacz School of Business - National-Louis University | And 5 more authors.
Proceedings. Biological sciences / The Royal Society | Year: 2015

The alleles that are detrimental to health, especially in older age, are thought to persist in populations because they also confer some benefits for individuals (through antagonistic pleiotropy). The ApoE4 allele at the ApoE locus, encoding apolipoprotein E (ApoE), significantly increases risk of poor health, and yet it is present in many populations at relatively high frequencies. Why has it not been replaced by natural selection with the health-beneficial ApoE3 allele? ApoE is a major supplier of cholesterol precursor for the production of ovarian oestrogen and progesterone, thus ApoE has been suggested as the potential candidate gene that may cause variation in reproductive performance. Our results support this hypothesis showing that in 117 regularly menstruating women those with genotypes with at least one ApoE4 allele had significantly higher levels of mean luteal progesterone (144.21 pmol l(-1)) than women with genotypes without ApoE4 (120.49 pmol l(-1)), which indicates higher potential fertility. The hormonal profiles were based on daily data for entire menstrual cycles. We suggest that the finding of higher progesterone in women with ApoE4 allele could provide first strong evidence for an evolutionary mechanism of maintaining the ancestral and health-worsening ApoE4 allele in human populations. © 2015 The Author(s) Published by the Royal Society. All rights reserved.


PubMed | Nowy Sacz School of Business - National-Louis University, Andrzej Frycz Modrzewski Cracow University, University of Tromsø, Polish Academy of Sciences and 2 more.
Type: Journal Article | Journal: Proceedings. Biological sciences | Year: 2015

The alleles that are detrimental to health, especially in older age, are thought to persist in populations because they also confer some benefits for individuals (through antagonistic pleiotropy). The ApoE4 allele at the ApoE locus, encoding apolipoprotein E (ApoE), significantly increases risk of poor health, and yet it is present in many populations at relatively high frequencies. Why has it not been replaced by natural selection with the health-beneficial ApoE3 allele? ApoE is a major supplier of cholesterol precursor for the production of ovarian oestrogen and progesterone, thus ApoE has been suggested as the potential candidate gene that may cause variation in reproductive performance. Our results support this hypothesis showing that in 117 regularly menstruating women those with genotypes with at least one ApoE4 allele had significantly higher levels of mean luteal progesterone (144.21 pmol l(-1)) than women with genotypes without ApoE4 (120.49 pmol l(-1)), which indicates higher potential fertility. The hormonal profiles were based on daily data for entire menstrual cycles. We suggest that the finding of higher progesterone in women with ApoE4 allele could provide first strong evidence for an evolutionary mechanism of maintaining the ancestral and health-worsening ApoE4 allele in human populations.


Bielecki A.,Jagiellonian University | Stocki R.,Nowy Sacz School of Business - National-Louis University
Cybernetics and Systems | Year: 2010

National health care systems have been found ineffective in most countries. The subsystems of the health care systems are not autonomous and as such cannot be competitive in the market. A participative health care system with empowered patients as customers and hospitals as providers is proposed. The consequences for both further modeling and implementation of such systems are discussed. Copyright © 2010 Taylor & Francis Group, LLC.


Szczyglowska R.,Glowny Instytut Gornictwa | Chyc M.,Nowy Sacz School of Business - National-Louis University | Burzala B.,Centralne Laboratorium | Kolwzan B.,Wroclaw University of Technology
Ochrona Srodowiska | Year: 2012

Water quality in indoor recreational objects (swimming pool, SPA, aquapark) is of paramount importance to the health of the users. Inadequate disinfection of swimming pool water may be the underlying cause of various diseases or afflictions. In the recreational object chosen for the study reported on here, water quality assessments were carried out using routine and extended microbiological and physicochemical analyses. It has been demonstrated that routine microbiological analysis failed to reliably assess the sanitary condition of the swimming pool water. In terms of routine microbiological indicators, water quality was satisfactory at all sampling sites but two. The two exceptions were in the SPA tubs and wading pools, where mesophilic bacteria alone were found to occur in excessive numbers (115 to 1000cfu/cm3). Only with extended microbiological analysis was it possible to detect the occurrence of bacteria of the Pseudomonas genus, including Pseudomonas aeruginosa. The water samples examined in this mode also displayed lower redox potential values (507 to 582 mV) and a lower free chlorine content (0 to 0.1 gCl2/m3). The periodical occurrence of Pseudomonas bacteria should, inter alia, be attributed to the stagnation of water in some parts of the installation, where their growth rate was found to exceed 100cfu/cm3, and where the presence of coagulase-positive staphylococci was detected. Pseudomonas bacteria were also present in the water samples collected from spray irrigators and rain showers. The results obtained make it clear that if the disinfection process is conducted without sufficient efficacy, the microorganisms growing in the swimming pool develop the potential for colonizing the installations, and thus pose health hazards to the swimmer.


Jasienska G.,Jagiellonian University | Jasienski M.,Nowy Sacz School of Business - National-Louis University | Ellison P.T.,Harvard University
Evolution and Human Behavior | Year: 2012

Most research shows that fatherhood is related to reduced testosterone (T) levels, but relationships between the number of children and T levels are not addressed. In humans, paternal care usually involves obtaining adequate resources to support children, which may require engaging in male-male competition and maintaining high T levels. We hypothesize that T levels in fathers should increase with increasing family size. In 78 Polish men, aged 30 to 77 years, the number of children was significantly correlated with paternal T levels, but the direction of this relationship was dependent on the fathers' education. In agreement with our hypothesis, in men with below-college education, T levels increased with increasing number of children. In contrast, in men with college education, the number of children was negatively related to paternal T levels. Drop in T levels throughout the day tended to be less pronounced the more children fathers had, irrespective of their educational level. Our results suggest that a hypothesis of simple trade-offs between mating and parenting effort may be too simplistic to explain changes in testosterone response to parenting in human males. In order to understand functional response of changes in T levels, it is crucial to account for family size and socioeconomic factors. However, due to the cross-sectional study design, we cannot exclude the possibility that T levels influenced reproductive behavior (rather than vice versa) and thus the number of children produced by men. © 2012 Elsevier Inc.


Jasienski M.,Nowy Sacz School of Business - National-Louis University
International Journal of Continuing Engineering Education and Life-Long Learning | Year: 2014

I discuss features that are important for creative and critical thinking which should be recreated in e-learning applications. Anonymity maximises chances for development of creativity and for objective and accurate assessment. I also describe a 'quadruple anonymity' system implemented at Nowy Sacz Business School - National-Louis University in Poland, the goal of which is to improve objectivity of thesis evaluation by referees. E-learning environment is ideal for implementing functionalities which make choice, feedback, and controlled anonymity easily available to the users to be effective, feedback should be appropriately timed, incremental, impartial, and impersonal. Evaluation of student or employee performance or of proposed ideas or solutions should rely on explicitly stated quantitative criteria, developed along well thought-through measurement scales and utilising proper descriptive statistics and visualisation methods. A description of the nominal group heuristic method is provided as an example of a heuristic method which relies on creativity, anonymity and unbiased evaluation. Copyright © 2014 Inderscience Enterprises Ltd.


Nowy Sacz School of Business - National-Louis University | Entity website

1991 . ...


Nowy Sacz School of Business - National-Louis University | Entity website

Nieustanny progres technologiczny oraz nowe wyzwania, stawiane przez dynamicznie rozwijajc si bran IT, day spoecznoci Wyszej Szkoy Biznesu National Louis University impuls do sprostania podlegajcych cigym zmianom wymaganiom rynku. Aby dotrzyma kroku tym zmianom i dziki odpowiedniemu poszerzeniu oferty Uczelni stworzy unikalne w skali kraju warunki rozwoju dla modych programistw, opracowano zaoenia i ramy instytucjonalne dla utworzenia w Nowym Sczu dziaajcego w obszarze multimediw Parku Technologicznego Nowej Generacji ...


Nowy Sacz School of Business - National-Louis University | Entity website

Zajcia prowadzone bd zgodnie z nowatorsk technik dydaktyczn: Nauczanie przez projekt Project-based learning(PBL) W czasie kursw zesp studentw zrealizuje zaawansowan aplikacj biznesow pracujc zgodnie z zasadami, ktre obowizuj w profesjonalnych zespoach programistycznych najwikszych firm wytwarzajcych oprogramowanie. Nauka programowania bdzie silnie poczona z realizacj projektu ...


Nowy Sacz School of Business - National-Louis University | Entity website

Instytut Diagnostyki, Opiniodawstwa i Pomocy Psychologicznej 2016

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