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Iosjpe M.,Norwegian Radiation Protection Authority
Journal of Marine Systems | Year: 2011

A sensitivity analysis has been carried out on the basis of the local and global sensitivity indexes for selected radionuclides (3H, 137Cs, 238Pu, 241Am and 244Cm) and main parameters describing the water-sediment interaction (sediment reworking rate, pore-water turnover rate, sediment distribution coefficient, suspended sediment load in water column, sedimentation rate, molecular diffusion coefficient, surface sediment thickness, porosity of bottom sediment and density of sediment material). Sensitivity analysis has been carried out using a compartment model for dose assessment to man and biota, which includes the processes of advection of radioactivity between compartments, sedimentation, diffusion of radioactivity through pore water in sediments, particle mixing, pore water mixing and a burial process of radioactivity in deep sediment layers.The sensitivity analysis indicates that for the conditions in the Norwegian Current (the Norwegian Sea) particle mixing dominates the transfer of radioactivity between the bottom water and surface sediment compartments. For the conditions in the Ob Bay (the Kara Sea), the sedimentation process has also been found to be significant.The calculated dynamics of the sensitivity indexes demonstrate clearly the complexities encountered when modeling water-sediment interactions. It is also shown that the results can be strongly dependent on the time of analysis. For example, given a specific change of parameters the radionuclide concentration will be either increased or decreased, depending on the temporal interval.Information provided by the sensitivity analysis can contribute to a better understanding of experimental data and might further improve the parameterization process. The obtained results show that water-sediment interactions can play a key role in the marine coastal environment, thus demonstrating the need to further deepen our understanding of them, as well as improve the models describing them. © 2011 Elsevier B.V. Source

Agency: Cordis | Branch: FP7 | Program: CP-FP | Phase: Fission-2010-3.2.1 | Award Amount: 7.04M | Year: 2011

Diagnostic radiation represents an indispensable, sometimes life-saving, tool in modern medicine. However, the growing use of computerized tomography (CT) is a topic of concern in radiological protection, especially for children and adolescents. Children are generally more sensitive to the carcinogenic effects of ionizing radiation than adults. In addition, they have a longer life-span to express any effect and, because of their smaller mass, they may receive higher radiation doses from a CT scan than an adult. A large-scale multinational collaborative study will be set up with the objective of providing guidance towards optimisation of doses from paediatric CT scans. We have the following specific aims: 1) describe the pattern of use of CT in different countries and over time; 2) derive individual estimates of organ doses ; 3) assess biological markers of CT-irradiation effects; 4) directly evaluate radiation-related risk of cancer following CT; and 5) characterize the quality of CT images in relation to the estimated doses in order to better inform CT imaging practice. Scientists from nine European countries with expertise in epidemiology, clinical practice, radiology, dosimetry, biology and public health will contribute to the project with the objective of provide recommendations for a harmonized approach to CT dose optimisation for paediatric patients in Europe. Results of this research will serve to increase awareness of the scientific and medical communities about public health aspects related to the use of diagnostic radiation and to provide recommendations on the use of valuable diagnostic tools, with lowering the risk of its potential hazards as much as possible.

Agency: Cordis | Branch: FP7 | Program: NoE | Phase: Fission-2010-3.5.1 | Award Amount: 8.04M | Year: 2011

With a renewed interest in nuclear energy and the scientific challenges related to the nuclear fuel cycle, the need for radioecological expertise is increasing world-wide. Concurrently, education related to radioecology has steadily declined, leading experts are approaching retirement, and funding for radioecological research is at a minimum in many European countries. To face this challenge and avoid further fragmentation, nine leading organisations propose to establish a Network of Excellence in radioecology, called STAR. The goal is to efficiently integrate important organisations, infrastructures, and research efforts into a sustainable network that contributes to a European Research Area in radioecology. To achieve this, a Joint Programme of Activities will be implemented covering integration and sharing of infrastructures; training, education and mobility; knowledge management and dissemination; as well as three key research themes (integrating human and non-human radiological risk assessments; radiation protection in a multi-contaminant context; ecologically relevant low-dose effects). The coordinator, IRSN, is one of the largest radioecological research institutes in Europe with an excellent record in large project management. Three STAR partners are members of the High Level Expert Group on Low Dose Risk Research, ensuring that STAR will provide effective links to the wider community of low dose risk research. STAR will interact with other European and international research institutes in radioecology, radiobiology and ecology to produce the best research for addressing the key scientific challenges in radioecology. To address stakeholders needs and policy questions, a strong link with end-users will be achieved via dedicated workshops, conferences and advanced dissemination tools. STAR will promote integration, networking and scientific excellence to benefit human and environmental radiation protection.

Agency: Cordis | Branch: FP7 | Program: CSA-SA | Phase: Fission-2012-6.0.1 | Award Amount: 1.45M | Year: 2013

The health effects of exposures to fallout from Soviet nuclear weapons testing among the residents living nearby the Semipalatinsk nuclear test site in Kazakhstan are not well investigated. There are reports with contradicting results coming from the studies conducted on two independent cohorts: historical and new. Both use different control groups and dosimetric methods. The two cohorts have a high probability of including the same individuals. There is a need to investigate possibilities to merge them in order to avoid duplication of efforts and resources for future studies of the health effects in these populations. The main objectives of our feasibility study include: developing and testing mechanisms for identification of cohort members in the two cohorts; identification and testing of data linkage mechanisms; determination of the outcomes that can be studied (cancer and non-cancer diseases); setting up and testing procedures for follow-up; identification of case ascertainment mechanisms and sources, depending on the outcome; characterization and validation of dose assessment methods used in the two cohorts; investigation of the feasibility to collect data on confounding factors; assessing the availability of biological samples and their potential use in the future. The project will bring together scientists from Europe, Kazakhstan and Japan with the aim of developing a proposal for a future prospective full scale epidemiological study to address the dose-effect relationship for both cancer and non-cancer effects from low to moderate chronic doses, if the feasibility is demonstrated. To achieve the overall objective it is proposed to set-up a consortium that have considerable experience in epidemiological studies on populations residing around the Semipalatinsk nuclear test site and/or who have been extensively involved in the low dose risk research. The group will include European and international scientists with expertise in epidemiology, dosimetry, radiation biology and clinical medicine. At the end of the project, a detailed report based on the results of the work conducted will be developed, critically reviewed by the External Advisory Board and recommendations for future research needs will be made, if feasible. Other populations exposed to low to moderate dose radiation like in Fukushima or elsewhere can benefit from the outcomes of studying the unique Semipalatinsk cohort and the results will contribute to a better understanding and quantification of radiation risks for low to moderate chronic doses. The proposed project is in line with the Strategic Research Agenda of MELODI.

Agency: Cordis | Branch: FP7 | Program: CSA-CA | Phase: Fission-2011-3.5.1 | Award Amount: 1.55M | Year: 2012

Creating a sustainable network in biological dosimetry that involves a large number of experienced laboratories throughout the EU will significantly improve the accident and emergency response capabilities in case of a large-scale radiological emergency. A well organised cooperated action involving EU laboratories will offer the only chance for a fast and trustworthy dose assessment urgently needed in an emergency situation. The goal of RENEB is to establish a sustainable European network in biological dosimetry involving 23 organisations from 16 countries identified by the TENEB survey, that will guarantee highest efficiency in processing and scoring of biological samples for fast, reliable results implemented in the EU emergency management. This goal will be achieved through 5 tasks: 1) To create an operational basis of the network, based on coordination of the existing reliable and proven methods in biological dosimetry. 2) To expand and improve the network implementing appropriate new, molecular biology methods and integrating new partners. 3) To assure high quality standards by education and training activities of members and interested non-members. Here, special focus will be placed on quality assurance and management regarding the performed assays and involved laboratories. 4) To develop an operational structure of the network including contacts to national first responders, a well organised transnational infrastructure to facilitate cross-border transport of human biological samples, a long term funding strategy and to prepare an agenda to transform RENEB into a legal organisation. 5) To guarantee dissemination of knowledge by providing access to internal and external communication platforms and databases and close cooperation with national and global emergency preparedness systems and organisations. All of these activities are strictly complementary to on-going projects in the EU Security Research Programme, specifically to MULTIBIODOSE and to EURADOS.

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