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Kovarik D.N.,Northwest Association for Biomedical Research | Patterson D.G.,University of Washington | Cohen C.,Cohen Research and Evaluation | Sanders E.A.,University of Washington | And 4 more authors.
CBE Life Sciences Education | Year: 2013

We investigated the effects of our Bio-ITEST teacher professional development model and bioinformatics curricula on cognitive traits (awareness, engagement, self-efficacy, and relevance) in high school teachers and students that are known to accompany a developing interest in science, technology, engineering, and mathematics (STEM) careers. The program included best practices in adult education and diverse resources to empower teachers to integrate STEM career information into their classrooms. The introductory unit, Using Bioinformatics: Genetic Testing, uses bioinformatics to teach basic concepts in genetics and molecular biology, and the advanced unit, Using Bioinformatics: Genetic Research, utilizes bioinformatics to study evolution and support student research with DNA barcoding. Pre-post surveys demonstrated significant growth (n = 24) among teachers in their preparation to teach the curricula and infuse career awareness into their classes, and these gains were sustained through the end of the academic year. Introductory unit students (n = 289) showed significant gains in awareness, relevance, and self-efficacy. While these students did not show significant gains in engagement, advanced unit students (n = 41) showed gains in all four cognitive areas. Lessons learned during Bio-ITEST are explored in the context of recommendations for other programs that wish to increase student interest in STEM careers. © 2013 D. N. Kovarik et al.


Chowning J.T.,Northwest Association for Biomedical Research | Griswold J.C.,Northwest Association for Biomedical Research | Kovarik D.N.,Northwest Association for Biomedical Research | Collins L.J.,Center for Research and Learning
PLoS ONE | Year: 2012

Developing a position on a socio-scientific issue and defending it using a well-reasoned justification involves complex cognitive skills that are challenging to both teach and assess. Our work centers on instructional strategies for fostering critical thinking skills in high school students using bioethical case studies, decision-making frameworks, and structured analysis tools to scaffold student argumentation. In this study, we examined the effects of our teacher professional development and curricular materials on the ability of high school students to analyze a bioethical case study and develop a strong position. We focused on student ability to identify an ethical question, consider stakeholders and their values, incorporate relevant scientific facts and content, address ethical principles, and consider the strengths and weaknesses of alternate solutions. 431 students and 12 teachers participated in a research study using teacher cohorts for comparison purposes. The first cohort received professional development and used the curriculum with their students; the second did not receive professional development until after their participation in the study and did not use the curriculum. In order to assess the acquisition of higher-order justification skills, students were asked to analyze a case study and develop a well-reasoned written position. We evaluated statements using a scoring rubric and found highly significant differences (p<0.001) between students exposed to the curriculum strategies and those who were not. Students also showed highly significant gains (p<0.001) in self-reported interest in science content, ability to analyze socio-scientific issues, awareness of ethical issues, ability to listen to and discuss viewpoints different from their own, and understanding of the relationship between science and society. Our results demonstrate that incorporating ethical dilemmas into the classroom is one strategy for increasing student motivation and engagement with science content, while promoting reasoning and justification skills that help prepare an informed citizenry. © 2012 Chowning et al.


News Article | December 20, 2016
Site: www.prweb.com

Dr. Stephen J. Rosenfeld, Executive IRB Chair for Quorum Review IRB, has accepted an invitation from Sylvia Burwell, the Secretary of the Department of Health and Human Services (DHHS), to chair the Secretary’s Advisory Committee for Human Research Protections (SACHRP). SACHRP comprises experts in the fields of research and ethics, and provides advice and recommendations to the Secretary of DHHS on issues pertaining to the protection of human subjects in research. “I am pleased to accept this position”, Dr. Rosenfeld said, observing that medical research is changing rapidly. “Ethics review committees are struggling with the blurring of distinctions between research, health care, and the activities of daily living, and we owe it to society and to our children to address these issues responsibly, consistently, and with transparency. I look forward to working with SACHRP to formulate policy recommendations for the Secretary [of DHHS].” Dr. Rosenfeld has served on SACHRP for three years and Dr. Burwell invited him to begin his new post immediately. He will serve as the SACHRP Chair until July of 2020. Professionally, Dr. Rosenfeld spent 19 years at the National Institutes of Health (NIH), where his experience culminated in the role of Chief Information Officer of the Clinical Center. He also has served in executive leadership positions in the private sector, both as the CIO of Maine Health and as the CEO of a leading independent IRB. Dr. Rosenfeld has earned degrees from Yale and Cornell, trained in Internal Medicine at Dartmouth and in Hematology at the NIH, and holds a Master’s in Business Administration from Georgetown University. “Dr. Rosenfeld is a thought leader who understands the practical aspects of complex issues,” says Cami Gearhart, CEO of Quorum, “SACHRP will benefit from his leadership and expertise.” Dr. Rosenfeld is active in MRCT (Multi-Regional Clinical Trials initiative), CTTI (Clinical Trials Transformation Initiative, ACRES (Alliance for Clinical Research Excellence and Safety), NWABR (Northwest Association for Biomedical Research), and has served as a guest lecturer for the Harvard Center for Bioethics. In 2013, Dr. Rosenfeld received the honor of Distinguished Professor of Medicine from Daegu Catholic University Medical Center in Korea. About Quorum Quorum Review IRB is the first name in streamlined, service-centered independent ethics and regulatory review. The Quorum difference is One-Touch Collaboration™. Your research benefits from an outstanding service experience, a single point of contact, one study startup timeline, and a true single board review—which is why Quorum is the preferred central IRB. Our service offerings include full study review in the U.S. and Canada, international ethics review, a specialized Cambridge Oncology Board, and unique processes to accelerate minimal risk research. Quorum works closely with institutions and researchers on studies from all over the world. Kinetiq, the consulting and technology division of Quorum, provides services that enhance and optimize the clinical research process.


2nd Annual Genome Editing & Engineering Conference to be held on 6th - 7th February 2017 in San Diego, CA will see participation from global experts from pharmaceutical, bio-pharmaceutical companies, universities and academic institutions. -- MarketsandMarkets, organizers of the 2Annual Genome Editing & Engineering Conference, are thrilled to announce that Dr. Dana Carroll, Distinguished Professor, Department of Biochemistry, University of Utah School of Medicine has joined the prestigious speaker panel at the conference taking place in San Diego.Dr. Carroll, a pioneer in the development and applications of genome editing with programmable nucleases, will be delivering the keynote on 'Issues in Programmable Genome Editing' helping provide key insights on how gene editing has powerful applications in various areas including agriculture and medicine.The conference will gather key industry leaders and researchers from research institutes, academic institutions, pharma and bio – pharma organizations to address the concepts, challenges and applications of genome editing tools like CRISPR/Cas9, TALENs. Key discussions at the event will include RNA guided nuclease for genome modifications, different gene delivery systems, CRISPR as a molecular tool for programmable gene expression and gene therapy, human gene therapy using Zebrafish model, gene knock in and genomic screening using TALEN and CRISPR, CRISPR biomedical research applications, RNAi based screening technologies, genome editing for disease modeling and NgAgo as the latest tool for genome editing.The marketing team at MarketsandMarkets did a small pre – event interview with Dr. Carroll, talking about the emerging research areas in genome editing and engineering for the treatment of disorders. Dr. Carroll mentioned a few areas where gene editing has been instrumental in finding results namely 'Improvement of the efficiency of homologous repair to allow easy gene correction', 'Delivery methods for in vivo treatments' and 'Development of "universal" donor cells to allow more affordable treatments'. He further added, "Genome editing depends on cellular DNA repair activities, so research on aspects of genome editing will help us learn more about those activities."Joining him on the speaker panel will be genomics experts representing organizations such as University of Utah School of Medicine, Massachusetts Institute of Technology, J. Craig Venter Institute, University of Nebraska Medical Center, University of California, University of Washington, University of Southern California, University of Rochester, National Institutes of Health, University of Texas, University of Minnesota, Hiroshima University and Wellcome Trust Sanger Institute. bThe conference will be an excellent opportunity to network, share expertise with industry peers and stay updated about the latest advancements in genomics and gene engineering. The conference is supported by California Life Sciences Association (CLSA), ArizonaBio, BioUtah, Colorado BioScience Association, Georgia Bio, Northwest Association for Biomedical Research (NWABR) and The Bioscience Association of Maine (BAM). The event is co - located with the 2Annual Biomarker Conference and 2Annual NGS Data Analysis and Informatics Conference and is scheduled for 6th – 7th February 2017.


Perry D.,University of Washington | Aragon C.,University of Washington | Cruz S.,University of Washington | Peters M.A.,Sage Bionetworks | And 2 more authors.
ACM International Conference Proceeding Series | Year: 2013

Engaging students in science, technology, engineering, and math (STEM) fields is critical to ensure the success of the next generation of scientists and engineers. Given that 97% of American teens play video games, there is a tremendous opportunity to facilitate interest in STEM topics through the design of engaging learning games. While a growing number of serious games have been developed for biological science and computer science learning, few address the communication and technical challenges that arise in cyberinfrastructure intensive projects, where multiple domain scientists and computer scientists collaborate. This paper describes empirical data collected during a year-long human centered game design process, in which design ideas generated by high school students were bridged with cyberinfrastructure and bioinformatics learning concepts. Our research shows that "fun" and engaging game elements are well suited for addressing the sociotechnical aspects of cyberinfrastructure projects. In this research we provide a human centered game design methodology for science educators and science game designers, as well as design implications for integrating game-based experiences into the use of large-scale shared computing resources and services. © 2013 by the Association for Computing Machinery, Inc.


Melvin A.J.,University of Washington | Edwards K.,University of Washington | Malone J.,University of Washington | Hassell L.,University of Washington | And 3 more authors.
Clinical and Translational Science | Year: 2013

This paper is a case study of our regional Clinical Translational Science Award's (CTSA) development of a coordinated response to the advanced notice of proposed rulemaking on Human Subjects Research Protections during the fall of 2011. Our CTSA was well positioned to quickly activate and coordinate a response to this important and time sensitive issue because we had established infrastructure and resources both within our CTSA and through our partnering institutions, existing relationships with key individuals in the institutions, and credibility as a trusted source of information. Three town hall meetings were organized and a Website was created to collect online comments. Ultimately, comments were collected, prioritized, and organized into a single, coordinated response. This case study demonstrates the value of a distributed research infrastructure and the role CTSAs like our Institute of Translational Health Sciences can play to engage the regional research community about important developments in the research landscape and to respond to requests for feedback to policy makers. © 2013 Wiley Periodicals, Inc.

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