Monterrey, Mexico

Northern University of Mexico

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Monterrey, Mexico
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Grant
Agency: European Commission | Branch: H2020 | Program: ERC-COG | Phase: ERC-CoG-2014 | Award Amount: 2.00M | Year: 2016

European incursions onto the narrow isthmian pass that divided and connected the Atlantic and Pacific oceans made it a strategic node of the Spanish Empire and a crucial site for early modern globalization. On the front lines of the convergence of four continents, Old Panama offers an unusual opportunity for examining the diverse, often asymmetrical impacts of cultural and commercial contacts. The role of Italian, Portuguese, British, Dutch, and French interests in the area, as well as an influx of African slaves and Asian merchandise, have left a unique material legacy that requires an integrated, interdisciplinary approach to its varied sources. Bones, teeth and artifacts on this artery of Empire offer the possibility of new insights into the cultural and biological impact of early globalization. They also invite an interdisciplinary approach to different groups tactics for survival, including possible dietary changes, and the pursuit of profit. Such strategies may have led the diverse peoples inhabiting this junction, from indigenous allies to African and Asian bandits to European corsairs, to develop and to favor local production and Pacific trade networks at the expense of commerce with the metropolis. This project applies historical, archaeological and archaeometric methodologies to evidence of encounters between peoples and goods from Europe, America, Africa and Asia that took place on the Isthmus of Panama during the sixteenth and seventeenth centuries. Forging an interdisciplinary approach to early globalization, it challenges both Euro-centric and Hispano-phobic interpretations of the impact of the conquest of America, traditionally seen as a demographic catastrophe that reached its nadir in the so-called seventeenth-century crisis. Rather than applying quantitative methods to incomplete source material, researchers will adopt a contextualized, inter-disciplinary, qualitative approach to diverse agents involved in cultural and commercial exchange.


Grant
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: SC1-PM-22-2016 | Award Amount: 12.56M | Year: 2016

The ZikaPLAN initiative combines the strengths of 25 partners in Latin America, North America, Africa, Asia, and various centres in Europe to address the urgent research gaps (WP 1-8) in Zika, identifying short-and long term solutions (WP 9-10) and building a sustainable Latin-American EID Preparedness and Response capacity (WP 11-12). We will conduct clinical studies to further refine the full spectrum and risk factors of congenital Zika syndrome (including neurodevelopmental milestones in the first 3 years of life), and delineate neurological complications associated with Zika due to direct neuroinvasion and immune-mediated responses. Laboratory based research to unravel neurotropism, investigate the role of sexual transmission, determinants of severe disease, and viral fitness will envelop the clinical studies. Burden of disease and modelling studies will assemble a wealth of data including a longitudinal cohort study of 17,000 subjects aged 2-59 in 14 different geographic locations in Brazil over 3 years. Data driven vector control and vaccine modelling as well as risk assessments on geographic spread of Zika will form the foundation for evidence-informed policies. The Platform for Diagnostics Innovation and Evaluation will develop novel ZIKV diagnostic tests in accordance with WHO Target Product Profiles. Our global network of laboratory and clinical sites with well-characterized specimens is set out to accelerate the evaluation of the performance of such tests. Based on qualitative research, we will develop supportive, actionable messages to affected communities, and develop novel personal protective measures. Our final objective is for the Zika outbreak response effort to grow into a sustainable Latin-American network for emerging infectious diseases research preparedness. To this end we will engage in capacity building in laboratory and clinical research, collaborate with existing networks to share knowledge and tackle regulatory and other bottlenecks.


Fernandez-Lopez S.R.,Complutense University of Madrid | Chong-Diaz G.B.,Northern University of Mexico
Palaeogeography, Palaeoclimatology, Palaeoecology | Year: 2014

The first circum-Pacific record of the Bajocian dimorphic ammonite Strigoceras septicarinatum, from the Quebrada San Pedro area, Antofagasta, northern Chile, is described and illustrated. Morphological features of two specimens display macroconch and microconch characters of a single biospecies, usually assigned to separate morphospecies of the West Tethyan genera Strigoceras [macroconch] and Cadomoceras [microconch]. Preservational features of these two specimens, found in situ in the same stratigraphic level at the top of the Torcazas Formation, correspond to resedimented elements of the uppermost Bajocian Dimorphinites Biohorizon, contemporaneous with the sedimentary matrix. These specimens represent dimorphic shells produced by extremely scarce individuals inhabiting the Tarapaca Basin, without evidence of lasting biostratinomic modifications such as sorting by necroplanktic drift or biostratinomic encrusting. In the Tarapaca Basin, the distribution of ammonite shells was taphonomically and ecologically driven by regional changes of relative sea level. Taphonomic, paleoecological and paleobiogeographical observations in the areas of Quebrada San Pedro and Caracoles corroborate the development of an advanced-deepening phase, with episodes of sedimentary starvation, during the uppermost Bajocian, Parkinsoni Zone. This phase characterizes the last episode within a deepening half-cycle of a third order and the maximum deepening of a second-order, transgressive/regressive facies cycle, in the marine, back-arc Tarapaca Basin during the Bajocian-Bathonian interval. These paleontological and paleoenvironmental results represent new criteria to characterize the Dimorphinites Biohorizon in the Tarapaca Basin, allowing the identification the upper Bajocian Parkinsoni Zone in the East Pacific Subrealm, as well as chronocorrelation between the West Tethyan and East Pacific basins at the Bajocian/Bathonian boundary. © 2014 Elsevier B.V.


Patent
Pontificia University Javeriana and Northern University of Mexico | Date: 2010-03-17

The invention refers to the design, synthesis and evaluation of 6 synthetic oligopeptides, that have not been previously described, designed from the T and B epitopes of allergens of group I of intradomiciliary mites of the species Dermatophagoides pteronyssinus, Dermatophagoides farinae and Blomia tropicalis, which can be used in the immunomodulation of individuals having immunocompetent systems and in the production of IgY polyclonal antibodies. The invention relates to a first method for obtaining a composition of IgY polyclonal antibodies that can be used as a diagnostic reagent having low cost and high reactivity in respect of intradomiciliary mites, and a second method for the detection of mite allergens, using the IgY antibody composition developed in the first method. The invention further relates to the composition of the IgY polyclonal antibodies.


The invention refers to the design, synthesis and evaluation of 6 synthetic oligopeptides, that have not been previously described, designed from the T and B epitopes of allergens of group I of intradomiciliary mites of the species Dermatophagoides pteronyssinus, Dermatophagoides farinae and Blomia tropicalis, which can be used in the immunomodulation of individuals having immunocompetent systems and in the production of IgY polyclonal antibodies. The invention relates to a first method for obtaining a composition of IgY polyclonal antibodies that can be used as a diagnostic reagent having low cost and high reactivity in respect of intradomiciliary mites, and a second method for the detection of mite allergens, using the IgY antibody composition developed in the first method. The invention further relates to the composition of the IgY polyclonal antibodies.


Herrera C.,Northern University of Mexico | Custodio E.,University of Barcelona
Science of the Total Environment | Year: 2014

The island of Fuerteventura is the oldest of the Canary Islands' volcanic archipelago. It is constituted by volcanic submarine and subaerial activity and intrusive Miocene events, with some residual later volcanism and Quaternary volcanic deposits that have favored groundwater recharge. The climate is arid, with an average rainfall that barely attains 60mm/year in the coast and up to 200mm/year in the highlands. The aquifer recharge is small but significant; it is brackish due to large airborne atmospheric salinity, between 7 and 15gm-2year-1 of chloride deposition, and high evapo-concentration in the soil. The average recharge is estimated to be less than about 5mm/year at low altitude and up to 10mm/year in the highlands, and up to 20mm/year associated to recent lava fields. Hydrochemical and water isotopic studies, supported by water table data and well and borehole descriptions, contribute a preliminary conceptual model of groundwater flow and water origin in the Betancuria area, the central area of the island. In general, water from springs and shallow wells tends to be naturally brackish and of recent origin. Deep saline groundwater is found and is explained as remnants of very old marine water trapped in isolated features in the very low permeability intrusive rocks. Preliminary radiocarbon dating indicates that this deep groundwater has an apparent age of less than 5000years BP but it is the result of mixing recent water recharge with very old deep groundwater. Most of the groundwater flow occurs through the old raised volcanic shield of submarine and subaerial formations and later Miocene subaerial basalts. Groundwater transit time through the unsaturated zone is of a few decades, which allows the consideration of long-term quasi-steady state recharge. Transit times are up to a few centuries through the saturated old volcanics and up to several millennia in the intrusive formations, where isolated pockets of very old water may exist. © 2014 Elsevier B.V.


The present invention discloses a heat transfer chain comprising circular links made from elliptical cross section solid wire, having a greater radius: lesser radius ratio of 1.5 to 3.0, having the axis formed by the greater radius of the elliptical section lined up with the diametrical direction of the circular link, achieving this way an increase in the chains durability (less wear in time), and at the same time obtaining greater heat transfer efficiency due to a high surface area to unit of mass (ton) ratio in the installed chain. The present invention may be applied primarily to rotating chain furnaces, wherein these experiment transitory increases and reductions in temperature, for heat transfer between two or more phases, commonly seen in the concrete, paper and fertilizer industries.


Patent
Northern University of Mexico and Sociedad Biotecnologia Y Bioingenieria Core S.A. | Date: 2012-05-09

The present invention relates to a device for controlling the pressure of a gas in a circuit by means of the generation of bubbles through a liquid, when this effect is used to produce a continuous positive pressure in the airway (CPAP) . The invention comprises a receptacle containing a liquid; a bubble tube with one end located outside the fluid connected to a device connected to a patients respiratory tract and the other end located within the liquid; and means for adjusting the level of liquid in the receptacle. The device may also comprise, in addition to the aforesaid, means to stabilize the liquid level inside the receptacle, moistening and heating means located inside the receptacle, and a gas-recycling system that conveys all or a portion of the gases generated in the receptacle towards the moistening and heating device.


Patent
Northern University of Mexico | Date: 2010-01-30

The present invention is related to providing a device for sampling, diluting and analyzing particles and substances normally located on surfaces, wherein said device comprises a collection system which, through a rotating collecting surface and a scraper gather the sample. The device also comprises a tank-like storage system to store the diluting solution and a dilution chamber that permits the sample to mix with the solution and be diluted. This mixture is subsequently placed in contact with a detection system which is capable of discerning the presence or not of the substance being sampled.


Patent
Socieded Biotecnologia y Bioingenieria Core S.A. and Northern University of Mexico | Date: 2010-07-02

The present invention relates to a device for controlling the pressure of a gas in a circuit by means of the generation of bubbles through a liquid, this effect being is used to produce a continuous positive airway pressure (CPAP). The invention comprises a container containing a liquid; a bubble tube with one end located outside the liquid connected to a device connected to a patients respiratory tract and the other end located within the liquid; and means for adjusting the level of liquid in the container. The device may also comprise, in addition to the aforesaid, means to stabilize the liquid level inside the container, humidifying and heating means located inside the container, and a gas-recycling system that conveys all or a portion of the gases generated in the container towards the humidifying and heating device.

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