Aljahdali M.,Northern Borders University |
Aljahdali M.,King Abdulaziz University
Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy | Year: 2013
The ternary complexes of Cu(II), Zn(II), Ni(II) and Cd(II) with 2-aminomethylbenzimidazole (AMBI) and glycine as a representative example of amino acids have been isolated and characterized by elemental analyses, IR, ESR, UV-vis, magnetic moment, molar conductance and 1H NMR spectra. AMBI behaves as neutral bidentate ligands with coordination through imidazole and amino group nitrogens while the glycine amino acid behaves as a monodenate anion with coordination involving the amino group and carboxylate oxygen after deprotonation. The magnetic and spectral data indicates a square planar geometry for both Cu2+ and Ni2+ complexes and a tetrahedral geometry for both Zn2+ and Cd2+ complexes. The isolated chelates have been screened for their antifungal and antibacterial activities using the disc diffusion method. A cytotoxicity of the compounds against colon (HCT116) and larynx (HEP2) cancer cells have been studied. The stability constants of ternary M-AMBI-Gly complexes were determined potentiometrically in aqueous solution at I = 0.1 mol dm-3 NaCl. © 2013 Elsevier B.V. All rights reserved.
Chidrawar V.R.,Northern Borders University
Asian Pacific Journal of Tropical Disease | Year: 2016
Objective: To evaluate the role of nifedipine (L-type of calcium channel blocker), glibenclamide [cystic fibrosis transmembrane conductance regulator (CFTR) channel blocker], niflumic acid (chloride channels blocker) and 2-aminoethyldiphenyl borate (calcium release-activated channels channel blocker) against chemically induced inflammatory bowel disease in male Wistar rats. Methods: Inflammatory bowel disease was induced by the administration of 2,4-dinitrobenzene sulfonic acid intracolonically. Animals were divided into 7 groups by keeping 6 animals in each group. Group one and two were treated as normal control and disease control, respectively and seven pretreated with sulfasalazine and remaining groups were treated with test drugs. Animals were pretreated for 5 days before administration of 2,4-dinitrobenzene sulfonic acid. Various parameters were recorded during and after treatment period like disease activity index (body weight, food intake, diarrhea score, occult blood score), biomarkers study in peritoneal macrophages and histopathology of colon. Results: Glibenclamide had offered significant protective effect on disease activity index, biochemical parameters confirmed by histopathological examination. 2-Aminoethyldiphenyl borate and niflumic acid had also shown insignificant protection in few parameters. Conclusions: Protection observed by pretreatment of glibenclamide is may be of its blocking effect of CFTR channels of the mast cells, which regulate chloride influx and efflux phenomenon. © 2016 Asian Pacific Tropical Medicine Press.
Abdelaziz T.H.S.,Helwan University |
Abdelaziz T.H.S.,Northern Borders University
IET Control Theory and Applications | Year: 2013
This paper considers the robust pole assignment problem using combined velocity and acceleration feedbacks for matrix second-order linear systems. The necessary and sufficient conditions which ensure solvability are derived. Based on recently developed parametric solution to the eigenstructure assignment problem by velocity-plus-acceleration feedback, a new technique is described to perform robust pole placement for second-order systems. The available degrees-of-freedom offered by the velocity-plus-acceleration feedback in selecting the associated eigenvectors are utilised to improve robustness of the closed-loop system. The main advantage of the described approach is that the problem is tackled in the second-order form without transformation into the first-order form. Finally, several examples are introduced to demonstrate the effectiveness of the proposed approach. © The Institution of Engineering and Technology 2013.
Khan A.D.,Sarhad University of Science and Information Technology |
Khan S.D.,University of Milan Bicocca |
Khan R.U.,Sarhad University of Science and Information Technology |
Ahmad N.,Northern Borders University
Plasmonics | Year: 2014
The presence of plasmonic Fano-like resonances in the optical response of isolated and dimer metal-dielectric-metal nanostructures are investigated theoretically. The nanostructures are engineered in such a way to support multiple Fano-like resonances that are induced by the interference of bright and dark plasmon modes. It is found that the dimer resonators exhibit different types of Fano resonances for both the transverse and longitudinal polarizations unlike conventional nanodimers. Several configurations of the dimer Fano resonator are analyzed with special emphasis on the Fano spectral line shape. Breaking the symmetry of the dimer nanostructure in various directions control the asymmetric line shape and provides different kinds of unique Fano resonances. In certain cases, the Fano resonators exhibit multiple Fano resonances that are particularly significant for plasmon line shaping and can serve as platforms for multi-wavelength sensing applications. © Springer Science+Business Media New York 2013.
El-Mallawany R.,Northern Borders University
Journal of Non-Crystalline Solids | Year: 2013
Binary tellurite glasses in the form (100 - x)TeO2-xA nOm and AnOm = Nb2O 5 and WO3 oxides have been prepared by the melt quenching technique and x = 4, 10 mol% for Nb2O5 and 20 mol% WO 3. Density and molar volume have been measured and calculated. Differential scanning calorimetric curves of these glasses have been investigated to measure thermal properties of these glasses. The thermal properties were the glass transition temperature Tg (C), the onset of crystallization temperature Tx (C) and the glass stability S = (Tx - Tg) (C). The glass transition temperature has been analyzed according to the average crosslink density that is present in the glass. © 2013 Elsevier B.V.