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Boston, MA, United States

Northeastern University is a private nonprofit research university located in Boston, Massachusetts. The university features a range of undergraduate and graduate programs leading to degrees through the doctorate in nine colleges and schools, as well as advanced degrees at graduate campuses in Charlotte, North Carolina, and Seattle, Washington.Northeastern's main campus is located in the Fenway, Roxbury, South End, and Back Bay neighborhoods. The university has roughly 16,000 undergraduates and almost 8,000 graduate students. Northeastern is categorized as a RU/H Research University by the Carnegie Classification of Institutions of Higher Education. In 2011, Northeastern opened the George J. Kostas Research Institute for Homeland Security.Northeastern features a cooperative education program that integrates classroom study with professional experience on seven continents. In 2012-2013, 7,968 students participated in the co-op program.The Northeastern University Huskies compete in the NCAA Division I as members of Colonial Athletic Association in 18 varsity sports offered by the CAA. The men's and women's hockey teams compete in Hockey East, while the men's and women's rowing teams compete in the Eastern Association of Rowing Colleges and Eastern Association of Women's Rowing Colleges , respectively. In 2013, men's basketball won its first CAA regular season championship, men's soccer won the CAA title for the first time, and women's ice hockey won a record 16th Beanpot championship. Wikipedia.

Northeastern University | Date: 2015-12-14

A glucose sensor suitable for measuring glucose levels in human saliva is provided. Systems containing the glucose sensor and methods for making and using the sensor are also provided. The glucose sensor is highly sensitive and can detect glucose levels at least down to 5 ppm. Fabrication of the sensor involves depositing single-walled carbon nanotubes onto the surface of a working electrode in a 3 electrode electrochemical detector and functionalizing the nanotubes by depositing layers of polymers, metallic nanoparticles, and glucose oxidase enzyme onto the nanotubes. The sensor can be used as a disposable, single-use device or as part of an analytical system, such as a microfluidics system, for the analysis of multiple analytes. The sensor enables the diagnosis and monitoring of diabetes to be performed without pain or the need for finger pricks in a home or clinical setting.

Northeastern University | Date: 2015-03-26

Devices and methods for directing a magnetic field into a body party of a subject are provided. The devices include at least one electromagnetic coil, a magnetic core or yoke, and a pair of flux concentrators. The flux concentrators are separated by a gap into which the body part fits and through which the flux concentrators focus the magnetic field. The devices allow magnetic fields to be transmitted through the gap with higher intensity at greater distances from the device than possible with previous designs. The methods of using such devices allow the delivery of magnetic fields with higher intensity to the interior of a body part without exposing interposed proximal regions to magnetic fields of unduly high intensity. The devices and methods are useful for deep transcranial magnetic stimulation of the brain to treat various medical conditions.

Northeastern University | Date: 2015-04-08

A zipper guide is provided to facilitate closure of an open-ended zipper. The zipper guide includes a base to which a zipper tape pin end is attached and a slider to which a zipper tape box end is attached. A key on a lower surface of the slider slides in a trench in an upper surface of the base at an orientation that guides the attached zipper tape box end toward the attached zipper tape pin end by planar sliding movements of the slider lower surface with respect to the base upper surface.

Northeastern University | Date: 2015-01-02

Biodegradable pH altering polymers are disclosed. In accordance with certain aspects, the biodegradable pH altering polymers may be used to alter the pH of a microenvironment. In accordance with other aspects, the biodegradable pH altering polymers are utilized for targeted drug and gene delivery and their spontaneous release in intracellular sites of interest.

The invention relates to a compound of the structural formula or a hydrate or an isotope thereof. The invention also relates to a preparation method thereof and methods of providing dietary organoselenium, inactivating an enzyme, modulating the activity of a protein (e.g., methyltransferase) or nucleic acid, identifying a methyltransferase that reacts with compound, and oxidizing a methyltransferase-reactive substrate.

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