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Changchun, China

Northeast Normal University is one of the six national universities in the People's Republic of China, located in Changchun, Jilin. The University was ranked No.37 in the comprehensive ranking of universities in China in 2013. Wikipedia.


Tao Y.,Northeast Normal University
Carpathian Journal of Food Science and Technology | Year: 2015

In recent years, in manufacture industry of fruit and vegetable juice and their drink, output value and profit both grow, production layout is optimized gradually, the potential of increase production is huge, and the leading enterprises expand rapidly and in a trend of stable development. Through comprehensively analysis on vegetable juice beverage market before and after 2012, this paper stated the development situation of fruit and vegetable drink in our country, and simply introduced production technological process of drink manufacture industry taking corn stalk drink as an example, thereby improving the cognition of public on fruit and vegetable drinks and the green image of drink manufacture industry, thus to motivate economical development of fruit and vegetable drink manufacture industry.


Li L.-S.,Northeast Normal University
Astrophysics and Space Science | Year: 2012

Perturbative post-Newtonian variations of the standard osculating orbital elements are obtained by using the two-body equations of motion in the parameterized post-Newtonian theoretical framework. The results obtained are applied to the Einstein and Brans-Dicke theories. As a results, the semi-major axis and eccentricity exhibit periodic variation, but no secular changes. The longitude of periastron and mean longitude at epoch experience both secular and periodic shifts. The post-Newtonian effects are calculated and discussed for six extrasolar planets. © 2012 The Author(s).


Li L.-S.,Northeast Normal University
Chinese Astronomy and Astrophysics | Year: 2012

In this paper we investigate the influence of a varying gravitation constant on the orbits of celestial bodies. Regarding the eccentric anomaly as an independent variable, we find the solutions to the perturbed equations of motion. In the first order solutions, we find the secular and periodic variations in semi-major axis. For the other orbital elements only periodic variations exhibit. However in the second order solutions, the longitude of periastron and the mean longitude have secular terms. Applying the calculations to six selected binaries, we give the numerical estimations of the variations of orbits. These results are then carefully compared and discussed. © 2012.


Lu S.,Northeast Normal University
International Geoscience and Remote Sensing Symposium (IGARSS) | Year: 2013

Many hyperspectral vegetation indices can be used to estimate the biochemical contents such as pigment content, nondestructively. These reflectance indices are influenced by some leaf surface structure, such as wax, and the existence of the wax affects the performance of the indices on the estimation of the biochemical contents. This research studied the possible effects of the leaf surface wax on the reflectance of the same leaf before and after removal of leaf wax. We found that dewaxing had decreased the reflectance between wavelength 400 and 1000nm, and the decrease depends on the wavelength. The changes of 37 hyperspectral indices before and after the wax removal were compared. The results revealed that some indices such as PSNDb, R672/R550, SIPI and WBI were not affected much by the dewaxing process and are thought relatively robust to estimate the biochemical contents. © 2013 IEEE.


Hariadi Y.,University of Tasmania | Hariadi Y.,University of Jember | Marandon K.,Polytechnic Institute of LaSalle Beauvais | Tian Y.,Northeast Normal University | And 2 more authors.
Journal of Experimental Botany | Year: 2011

Ionic and osmotic relations in quinoa (Chenopodium quinoa Willd.) were studied by exposing plants to six salinity levels (0-500mM NaCl range) for 70d. Salt stress was administered either by pre-mixing of the calculated amount of NaCl with the potting mix before seeds were planted or by the gradual increase of NaCl levels in the irrigation water. For both methods, the optimal plant growth and biomass was achieved between 100mM and 200mM NaCl, suggesting that quinoa possess a very efficient system to adjust osmotically for abrupt increases in NaCl stress. Up to 95% of osmotic adjustment in old leaves and between 80% and 85% of osmotic adjustment in young leaves was achieved by means of accumulation of inorganic ions (Na+, K+, and Cl -) at these NaCl levels, whilst the contribution of organic osmolytes was very limited. Consistently higher K+ and lower Na+ levels were found in young, as compared with old leaves, for all salinity treatments. The shoot sap K+ progressively increased with increased salinity in old leaves; this is interpreted as evidence for the important role of free K+ in leaf osmotic adjustment under saline conditions. A 5-fold increase in salinity level (from 100mM to 500mM) resulted in only a 50% increase in the sap Na+ content, suggesting either a very strict control of xylem Na+ loading or an efficient Na+ removal from leaves. A very strong correlation between NaCl-induced K+ and H+ fluxes was observed in quinoa root, suggesting that a rapid NaCl-induced activation of H+-ATPase is needed to restore otherwise depolarized membrane potential and prevent further K+ leak from the cytosol. Taken together, this work emphasizes the role of inorganic ions for osmotic adjustment in halophytes and calls for more in-depth studies of the mechanisms of vacuolar Na+ sequestration, control of Na+ and K+ xylem loading, and their transport to the shoot. © 2010 The Author.


Si Y.,Jilin Agricultural University | Yang G.,Northeast Normal University
Journal of Materials Chemistry C | Year: 2013

The electronic circular dichroism (CD), UV-Vis absorption and emission spectra, charge transport, and nonlinear optical properties of the novel azaboradibenzo[6]helicene have been investigated by density functional theory (DFT) for the first time. The calculated absorption and emission energies are in good agreement with the experimental ones. The simulated CD spectra nicely reproduce the experimental CD spectra in both excitation energy and rotational strength without any shift or scaling, which can be used to assign its absolute configuration (AC) with high confidence. The electronic transition properties have been assigned and analyzed. The observed CD bands mainly result from exciton-coupling of the ortho-fused aromatic rings. The adiabatic potential energy surface method was used to calculate reorganization energy of the studied compound. The hole reorganization energy is slightly smaller than that of the electron reorganization energy. The largest bond-length changes upon reduction and oxidation are mainly localized on the rings containing B-N bonds. It is found that the photophysical properties of azaboradibenzo[6]helicene can be effectively tuned upon substitution. In view of the second-order polarizability value and intrinsic non-centrosymmetric electronic structure, the studied compounds have the possibility to be excellent second-order nonlinear optical materials. © 2013 The Royal Society of Chemistry.


Tian S.-C.,CAS Changchun Institute of Optics and Fine Mechanics and Physics | Tong C.-Z.,CAS Changchun Institute of Optics and Fine Mechanics and Physics | Wang C.-L.,Northeast Normal University | Ning Y.-Q.,CAS Changchun Institute of Optics and Fine Mechanics and Physics
Journal of Luminescence | Year: 2014

The resonance fluorescence spectrum from a triple quantum dot molecules controlled by tunneling is investigated. The positions, widths and heights of the resonance fluorescence peaks can be modified by the tunneling between the dots rather than the laser field, and interesting features such as controllable triple narrow peaks are obtained. The spectrum is explained with the transition properties of the dressed states generated by the coupling of the tunneling and the laser field. These features can also be viewed as the effects of spontaneously generated coherence between the close-lying states in the dressed state picture of the tunneling couplings, which can permit the observation of spontaneously generated coherence in quantum dot molecules. © 2014 Published by Elsevier B.V.


Liu M.,Harbin Institute of Technology | Wang K.,Harbin Institute of Technology | Wang K.,Northeast Normal University
Journal of Biological Systems | Year: 2011

Stochastic cooperation model of two species with generalized dose-response function in a polluted environment is studied. Sufficient criteria for extinction, non-persistence in the mean, weak persistence in the mean, strong persistence in the mean and stochastic persistence are established. The threshold between weak persistence in the mean and extinction for each species is obtained. Certain long-run-average limits of the solutions are represented by two constants in some cases. The results also reveal that both the stochastic noises and the dose-response function play important roles in determining the persistence or extinction of the species. © 2011 World Scientific Publishing Company.


Wong A.W.-K.,City University of Hong Kong | Wu Y.,Northeast Normal University | Chen H.-C.,Chinese University of Hong Kong
Neuroscience | Year: 2014

This study investigates the role of phonology in reading logographic Chinese. Specifically, whether phonological information is obligatorily activated in reading Chinese two-character compounds was examined using the masked-priming paradigm with event-related potential (ERP) recordings. Twenty-two native Cantonese Chinese speakers participated in a lexical decision experiment. The targets were visually presented Chinese two-character strings and the participants were asked to judge whether the target in each trial was a legitimate compound word in Chinese. Each target was preceded by a briefly presented word prime. The prime and target shared an identical constituent character in the Character-related condition, a syllable in the Syllable-related condition, were semantically related in the Semantic-related condition, and were unrelated (both phonologically and semantically) in the control condition. The prime-target relationship was manipulated to probe the effects of word-form (i.e., character- or syllable-relatedness) and word-semantic relatedness on phonological (as indexed by an N250 ERP component) and semantic (as indexed by an N400 ERP component) processing. Significant and comparable facilitation effects in reaction time, relative to the control, were observed in the Character-related and the Semantic-related conditions. Furthermore, a significant reduction in ERP amplitudes (N250), relative to the control, was obtained in the Character-related condition in the time window of 150-250. ms post target. In addition, attenuation in ERP amplitudes was found in the Semantic-related condition in the window of 250-500. ms (N400). However, no significant results (neither behavioral nor ERP) were found in the Syllable-related condition. These results suggest that phonological activation is not mandatory and the role of phonology is minimal at best in reading Chinese two-character compounds. © 2013 IBRO.


Yang X.,Harbin Normal University | Wang J.,Harbin Normal University | Su D.,Harbin Normal University | Xia Q.,Harbin Normal University | And 3 more authors.
Dalton Transactions | Year: 2014

Rapid and sensitive detection of 2,4,6-trinitrotoluene (TNT) and 4-nitrophenol (4-NP) has attracted considerable attention due to their wide applications as nitroaromatic explosive materials. A novel fluorescence method for TNT and 4-NP based on bovine serum albumin functionalized fluorescent gold nanoclusters (BSA Au-NCs) has been developed. The detection probe BSA Au-NCs can be used as a fluorescent probe for the sensitive and selective detection of TNT and 4-NP simultaneously. A good linearity of fluorescence detection using BSA Au-NCs as a fluorescent probe was observed for TNT and 4-NP concentrations in the range of 10-8-5 × 10-5 M and 10-9-5 × 10-5 M, with a detection limit of 10 nM and 1 nM, respectively. The high specificity of TNT and 4-NP with BSA Au-NCs interactions provided excellent selectivity towards detecting TNT and 4-NP over other relevant nitroaromatic compounds. This system can be applied to test strips to detect TNT and 4-NP with high sensitivity and selectivity. The vapour of TNT and 4-NP can be detected using BSA Au-NCs test paper within 1 min with a detection limit of 10 pM and 1 pM. © 2014 The Royal Society of Chemistry.


Wang X.,Jilin University | Wang X.,Changchun University of Science and Technology | Tian H.,Jilin University | Cui X.,Jilin University | And 2 more authors.
Dalton Transactions | Year: 2014

We successfully synthesized mesoporous ZnxCd1-xS/ reduced graphene oxide (ZxCSG) hybrid materials as photocatalysts using a facile one-pot hydrothermal reaction, in which graphene oxide (GO) was easily reduced (RGO), and simultaneously ZnxCd1-xS (Z xCS) nanoparticles (NPs) with a mesoporous structure were uniformly dispersed on the RGO sheets. By well tuning the band gap from 3.42 to 2.21 eV by changing the molar ratio of Zn/Cd (or Zn content), ZxCSG with an optimal zinc content has been found to have a significant absorption in the visible light (VL) region. In addition, under VL irradiation (λ > 420 nm), ZxCSG also showed zinc content-dependent photocatalytic efficiencies for the degradation of methylene blue (MB). Our findings are that, among ZxCSG, Z0.4CSG displayed not only a superior photodegradation efficiency of MB (98%), but also good removal efficiency of total organic carbon (TOC) (67%). Furthermore, Z0.4CSG had a high photocatalytic stability, and could be used repeatedly. The enhanced photocatalytic activity for Z0.4CSG could be attributed to a synergistic effect between mesoporous ZxCS NPs and RGO, including the optimal band gap and the moderate conduction band position for ZxCS (compared to CdS), efficient separation and transfer ability of photogenerated electron/hole pairs in the presence of RGO sheets, and relatively high surface area for both mesoporous ZxCS NPs and RGO. This journal is © the Partner Organisations 2014.


Ma P.,CAS Changchun Institute of Applied Chemistry | Xiao H.,University of Notre Dame | Li X.,Northeast Normal University | Li C.,CAS Changchun Institute of Applied Chemistry | And 5 more authors.
Advanced Materials | Year: 2013

By combining upconversion nanoparticles with the cisplatin (IV) prodrug we have demonstrated that a stable and multifunctional drug delivery system can be designed that will both reduce the drawbacks of cisplatin and give insight in to its in vitro/in vivo imaging. The up/down-conversion fluorescence are detectable and show obvious co-localization, demonstrating that the nanoparticles are rather stable inside cells and retain the UCNPs and block copolymer. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


Gandra N.,University of Oklahoma | Abbineni G.,University of Oklahoma | Qu X.,University of Oklahoma | Huai Y.,University of Oklahoma | And 2 more authors.
Small | Year: 2013

A photosensitizer, pyropheophorbid-a (PPa), is conjugated to SKBR-3 breast cancer cell-specific biological nanowire phage, to form a novel PPa-phage complex, which is further successfully used in selectively killing SKBR-3 breast cancer cells by the mechanism of photodynamic therapy (PDT). Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


Li X.,Northeast Normal University | Mao X.,University of Strathclyde
Automatica | Year: 2012

In this paper, we consider neutral stochastic delay differential equations with Markovian switching. Our key aim is to establish LaSalle-type stability theorems for the underlying equations. The key techniques used in this paper are the method of Lyapunov functions and the convergence theorem of nonnegative semi-martingales. The key advantage of our new results lies in the fact that our results can be applied to more general non-autonomous equations. © 2012 Elsevier Ltd. All rights reserved.


Irfan A.,King Khalid University | Al-Sehemi A.G.,King Khalid University | Muhammad S.,Osaka University | Zhang J.,Northeast Normal University
Australian Journal of Chemistry | Year: 2011

Theoretically calculated mobility has revealed that BDT is a hole transfer material, which is in good agreement with experimental investigations. The BDT, NHBDT, and OBDT are predicted to be hole transfer materials in the C2/c space group. Comparatively, hole mobility of BHBDT is 7 times while electron mobility is 20 times higher than the BDT. The packing effect for BDT and designed crystals was investigated by various space groups. Generally, mobility increases in BDT and its analogues by changing the packing from space group C2/c to space groups P1 or . In the designed ambipolar material, BHBDT hole mobility has been predicted 0.774 and 3.460cm2Vs-1 in space groups P1 and , which is 10 times and 48 times higher than BDT (0.075 and 0.072cm2Vs-1 in space groups P1 and ), respectively. Moreover, the BDT behaves as an electron transfer material by changing the packing from the C2/c space group to P1 and . © CSIRO 2011.


Zeng Z.,Northeast Normal University
Nonlinear Analysis: Real World Applications | Year: 2011

In this paper, the single species modelled by (asymptotically) periodic Gompertz equation is investigated. It is shown that the (asymptotically) periodic system has a unique (asymptotically) periodic solution which is globally asymptotically stable for the positive solution. When the nonautonomous Gompertz equation is subject to harvesting, we study the optimal harvesting policy for the periodic system and obtain the corresponding optimal population level and the maximum sustainable yield. Further, when the functions in the exploited Gompertz system are stably bounded functions, we study the ultimately optimal harvesting policy. By choosing the average limiting maximum sustainable yield as management objective, the corresponding optimal population level is determined. © 2010 Elsevier Ltd. All rights reserved.


Wang Y.,Northeast Normal University
Journal of Geometry and Physics | Year: 2010

We compute the transgressed forms of some modularly invariant characteristic forms, which are related to the twisted elliptic genera. We study the modularity properties of these secondary characteristic forms and relations among them. We also get some twisted anomaly cancellation formulas on some odd dimensional manifolds. © 2010 Elsevier B.V. All rights reserved.


Liu X.,Jilin University | Lin X.J.,Jilin University | Wang C.P.,Northeast Normal University | Yan K.K.,Jilin University | And 3 more authors.
Clinical Oncology | Year: 2014

Aims: To carry out a meta-analysis on the relationship between smoking and p53 gene mutation in lung cancer patients. Materials and methods: PubMed, Web of Science, ProQest and Medline were searched by using the key words: 'lung cancer or lung neoplasm or lung carcinoma', 'p53 mutation' and 'smoking'. According to the selection criteria, 15 articles were identified and methodologically analysed by stata 12.0 software package. Crude odds ratios with 95% confidence intervals calculated using the fixed-effects model were used to assess the strength of association between smoking and p53 mutation in lung cancer. Results: In total, 15 articles with 1770 lung cancer patients were identified; 69.6% of the patients were smokers, 30.4% were non-smokers. Overall, smokers with lung cancer had a 2.70-fold (95% confidence interval 2.04-3.59) higher risk for mutation than the non-smokers with lung cancer. In subgroup analyses, the increased risk of p53 mutation in smokers than in non-smokers was found in the non-small cell lung cancer (NSCLC) group (odds ratio=2.38, 95% confidence interval=1.71-3.32) and in the NSCLC and SCLC group (odds ratio=3.82, 95% confidence interval=2.19-6.69). Conclusions: This meta-analysis strongly suggests that p53 mutation is associated with smoking-induced lung cancer. Smokers with lung cancer had a higher risk for p53 mutation than non-smokers. © 2013 The Royal College of Radiologists.


Jin R.F.,Chifeng University | Chang Y.F.,Northeast Normal University
Physical Chemistry Chemical Physics | Year: 2015

A series of D-π-A star-shaped molecules with triphenylamine (TPA) as a core, 1,8-naphthalimide (NI) derivatives as end groups, and different p-bridges have been designed to explore their optical, electronic, and charge transport properties as organic solar cell (OSC) materials. The calculation results showed that the star-shaped molecules can lower the material band gap and extend the absorption spectrum towards longer wavelengths. The designed molecules own the longest wavelength of absorption spectra, oscillator strength, and absorption region values. Our results suggest that the designed molecules are expected to be promising candidates for OSC materials. Additionally, the molecules with ethyne, thiophene, benzo[c][1,2,5]thiadiazole (BTA), and 2,3-dihydrothieno[3,4-b][1,4]dioxine (DTD) as π-bridges and 4-pyridne, 4-aniline, and H in NI fragments have better hole- and electron transporting balance and can act as nice ambipolar materials. The values of hole mobility of molecules with ethyne as a π-bridge and NI as an end group for Pna21 and P21/c are 5.30 × 10-3 and 1.27 × 10-2 cm2 V-1 s-1, respectively. On the basis of the investigated results, we suggest that molecules under investigation are suitable donors of [6,6]-phenyl-C61-butyric acid methyl ester (PCBM) and its derivatives are acceptors of solar cells. © the Owner Societies 2015.


Zhang C.,Northeastern University China | Zhang C.,Key Laboratory of Symbol Computation | Ning J.,Northeast Normal University | Ouyang D.,Key Laboratory of Symbol Computation
Computers and Industrial Engineering | Year: 2010

A hybrid alternate two phases particle swarm optimization (PSO) algorithm called ATPPSO is proposed to solve the flow shop scheduling problem (FSSP) with the objective of minimizing makespan which combines the PSO with genetic operators and annealing strategy. In the ATPPSO algorithm, each particle contains two states, the attractive state and the repulsive state. In order to refrain from the shortcoming of premature convergence, a two point reversal crossover operator is defined and in the repulsive process each particle is repelled away from some inferior solution in the current tabu list to fly towards some promising areas which can introduce some new information to guide the swarm searching process. To preserve the swarm diversity, an annealing criterion is used to update the personal best of each particle. Moreover an easy understanding makespan computation method based on matrix is designed. Finally, the proposed algorithm is tested on different scale benchmarks and compared with the recently proposed efficient algorithms. The results show that both the solution quality and the convergence speed of the ATPPSO algorithm precede the other two recently proposed algorithms. It can be used to solve large scale flow shop scheduling problem effectively. © 2009 Elsevier Ltd. All rights reserved.


Wang X.,Jilin University | Wang X.,Changchun University of Science and Technology | Tian H.,Jilin University | Yang Y.,Jilin University | And 4 more authors.
Journal of Alloys and Compounds | Year: 2012

Reduced graphene oxide/cadmium sulfide (RGO/CdS) hybrid material was synthesized by a one-step solvothermal method, wherein graphene oxide (GO) was a supporting material on which CdS nanoparticles were distributed homogeneously, and cadmium acetate (Cd(Ac) 2·2H 2O) was used as the CdS precursor. The supporting material RGO for CdS nanoparticles effectively enhanced their photocatalytic activities for the photodegradation of methylene blue in the aqueous solution. The optimum weight ratio of the GO to CdS in the hybrid material was 5.0%, which exhibited an excellent photodegradation efficiency (94%) and a better removal efficiency of total organic carbon (TOC) (57%), about 2.5 times and 5.1 times higher than that of pure CdS nanoparticles, respectively, under visible light (VL) irradiation. This improved photodegradation efficiency could be attributed to the increased adsorbability for methylene blue molecules, light absorption levels located in visible region, high charge transfer and separation ability, due to the introduction of a two-dimensional RGO network. © 2012 Elsevier B.V.


Zhang L.,CAS Changchun Institute of Optics and Fine Mechanics and Physics | Zhang L.,University of Chinese Academy of Sciences | Li B.,CAS Changchun Institute of Optics and Fine Mechanics and Physics | Su Z.,Northeast Normal University | Yue S.,CAS Changchun Institute of Optics and Fine Mechanics and Physics
Sensors and Actuators, B: Chemical | Year: 2010

In this paper, we report the synthesis, characterization, and Fe(III)-sensing properties of two easily synthesized rare-earth(III)-based emitters, Na3Eu(PDA)3 and Na3Tb(PDA)3. Results suggest that the two emitters exhibit high sensitivity and linear spectral response towards Fe(III) (Stern-Volmer constant = 2.21 × 104 L/mol, linearity = 0.988). In addition, the two emitters are oxygen- and temperature-insensitive, making themselves promising candidates to be utilized in actual applications. © 2009 Elsevier B.V. All rights reserved.


Liu H.,Jilin University | Liu L.,Jilin University | Zhang H.,Northeast Normal University
Pattern Recognition | Year: 2010

Cancer diagnosis is an important emerging clinical application of microarray data. Its accurate prediction to the type or size of tumors relies on adopting powerful and reliable classification models, so as to patients can be provided with better treatment or response to therapy. However, the high dimensionality of microarray data may bring some disadvantages, such as over-fitting, poor performance and low efficiency, to traditional classification models. Thus, one of the challenging tasks in cancer diagnosis is how to identify salient expression genes from thousands of genes in microarray data that can directly contribute to the phenotype or symptom of disease. In this paper, we propose a new ensemble gene selection method (EGS) to choose multiple gene subsets for classification purpose, where the significant degree of gene is measured by conditional mutual information or its normalized form. After different gene subsets have been obtained by setting different starting points of the search procedure, they will be used to train multiple base classifiers and then aggregated into a consensus classifier by the manner of majority voting. The proposed method is compared with five popular gene selection methods on six public microarray datasets and the comparison results show that our method works well. © 2010 Elsevier Ltd. All rights reserved.


Wang L.,Northeast Normal University
Carpathian Journal of Food Science and Technology | Year: 2015

During the training of athletes, weight reduction and stamina recovery is an important trial of athletic contest. This paper systematically studies the interference of food such as functional drinks, vegetables, meat, eggs to somatic function when on weight reduction. This paper researches the influence of nutriology intervene on the blood index of athletes during slow weight reduction in training, fast weight reduction before the competition and stamina restoring ahead the competition. Twelve athletes of female weight lifting team were selected and divided into experimental group and control group, each with 6 athletes. Athletes of both groups took the same exercise training and diet with same energy. And compared with control group, the experimental group took slim bar and sports nutrition with electrolyte during weight reduction; and strengthened the sports nutrition with fast energy supplement preparations, vitamin and electrolyte during the stamina restoring stage while the control group took relevant placebo. Both groups received blood detection. The results suggested that creatine kinase and blood urea of experimental group during fast restoring stage was much lower than control group; the hemoglobin was higher than control group and the testosterone of both groups were with no difference. The concentration of serum potassium, sodium and calcium of experimental group during the fast weight reduction and restoring stage was distinctly higher than control group. The hunger degree of experimental group during weight reduction stage was lower than control group. Thus we reached the conclusion that the nutritious food intervene can help reduce weight and has fine hemoglobin level, serum creatine kinase level and serum inorganic ion level. This method can maintain the steadiness of internal environment of athletes during weight reduction.


Li L.-S.,Northeast Normal University
Research in Astronomy and Astrophysics | Year: 2012

A set of synchronous equations are derived from a set of non-synchronous equations. The analytical solutions are given by solving the set of differential equations. The results of the evolutionary trend of the spin-orbit interaction are that the semi-major axis gradually shrinks with time; the orbital eccentricity gradually decreases with time until orbital circularization occurs; the orbital period gradually shortens with time and the rotational angular velocity of the primary component gradually speeds up with time before the orbit achieves circularization. The theoretical results are applied to evolution of the orbit and spin of synchronous binary stars Algol A and B that are on the main sequence. The circularization time, lifetime and the evolutionary numerical solutions of orbit and spin when circularization time occurs are estimated for Algol A and B. © 2012 National Astronomical Observatories of Chinese Academy of Sciences and IOP Publishing Ltd..


Jiang T.,Northeast Normal University
The Journal of the Acoustical Society of America | Year: 2010

This study describes variation patterns in the constant frequency of echolocation calls emitted at rest and when not flying ("resting frequency" RF) of the least horseshoe bat, Rhinolophus pusillus, on a broad geographical scale and in response to local climatic variables. Significant differences in RF were observed among populations throughout the species range in Mainland China, and this variation was positively and significantly related to climate conditions, especially environmental humidity, but the variability was only weakly associated with geographical distance. Sex dimorphism in the RF of R. pusillus may imply that female and male might keep their frequencies within a narrow range for sex recognition. Moreover, bats adjusted resting frequency to humidity, which may imply partitioning diet by prey size or the influence of rainfall noise. The results indicate that bats adjust echolocation call frequency to adapt to environmental conditions. Therefore, environmental selection shape the diversity of echolocation call structure of R. pusillus in geographically separated populations, and conservation efforts should focus on changes in local climate and effects of environmental noise.


Wei J.-M.,Nankai University | Wang S.-Q.,Northeast Normal University | Yuan X.-J.,Nankai University
IEEE Transactions on Knowledge and Data Engineering | Year: 2010

Cancer classification is the critical basis for patient-tailored therapy. Conventional histological analysis tends to be unreliable because different tumors may have similar appearance. The advances in microarray technology make individualized therapy possible. Various machine learning methods can be employed to classify cancer tissue samples based on microarray data. However, few methods can be elegantly adopted for generating accurate and reliable as well as biologically interpretable rules. In this paper, we introduce an approach for classifying cancers based on the principle of minimal rough fringe. For training rough hypercuboid classifiers from gene expression data sets, the method dynamically evaluates all available genes and sifts the genes with the smallest implicit regions as the dimensions of implicit hypercuboids. An unseen object is predicted to be a certain class if it falls within the corresponding class hypercuboid. Based upon the method, ensemble rough hypercuboid classifiers are subsequently constructed. Experimental results on some open cancer gene expression data sets show that the proposed method is capable of generating accurate and interpretable rules compared with some other machine learning methods. Hence, it is a feasible way of classifying cancer tissues in biomedical applications. © 2006 IEEE.


Pan Y.,Tonghua Teacher College | Wang R.,Northeast Normal University
Chemical Physics | Year: 2010

The mechanisms for the reaction of CF3O2 with atomic hydrogen were studied with ab initio and DFT methods. The results reveal that the reaction could take place on the singlet and triplet potential energy surfaces (PES). For the singlet PES, addition/elimination and substitution mechanisms are determined, and the former one is dominant. The most favorable channel involves the association of CF3O2 with H atom to form CF3O2H (IM1) via a barrierless process, and then the O-O bond dissociates to give out CF3O + OH. The secondary product might be CF3OH + O, formed from the O-O bond cleavage in the initial adduct CF3O(H)O (IM2). Other products such as CF3 + O2H, HF + CF2O2 and O2 + CHF3 are of no importances because of higher barriers. On the triplet PES, only substitution mechanism is located. With higher barriers involving, the channels on the triplet PES could be negligible compared with the channels on the singlet PES. © 2009 Elsevier B.V. All rights reserved.


Wu Q.,South China Normal University | Wu Q.,CAS Wuhan Institute of Physics and Mathematics | Wu Q.,Guangdong Medical University | Zhang J.-Q.,CAS Wuhan Institute of Physics and Mathematics | And 3 more authors.
Optics Express | Year: 2015

In contrast to the optomechanically induced transparency (OMIT) defined conventionally, the inverse OMIT behaves as coherent absorption of the input lights in the optomechanical systems. We characterize a feasible inverse OMIT in a multi-channel fashion with a double-sided optomechanical cavity system coupled to a nearby charged nanomechanical resonator via Coulomb interaction, where two counter-propagating probe lights can be absorbed via one of the channels or even via three channels simultaneously with the assistance of a strong pump light. Under realistic conditions, we demonstrate the experimental feasibility of our model by considering two slightly different nanomechanical resonators and the possibility of detecting the energy dissipation of the system. In particular, we find that our model turns to be a unilateral inverse OMIT once the two probe lights are different with a relative phase, and in this case the relative phase can be detected precisely. © 2015 Optical Society of America.


Bhargava A.,University of British Columbia | Ahad A.,University of British Columbia | Wang S.,University of British Columbia | Wang S.,Northeast Normal University | And 4 more authors.
Planta | Year: 2013

The Arabidopsis thaliana KNAT7 (KNOX family) and MYB75 (MYB family) transcription factors were each shown earlier to interact in yeast two-hybrid assays, and to modulate secondary cell wall formation in inflorescence stems. We demonstrate here that their interaction also occurs in vivo, and that specific domains of each protein mediate this process. The participation of these interacting transcription factors in secondary cell wall formation was then extended to the developing seed coat through the use of targeted transcript analysis and SEM in single loss-of-function mutants. Novel genetic and protein-protein interactions of MYB75 and KNAT7 with other transcription factors known to be involved in seed coat regulation were also identified. We propose that a MYB75-associated protein complex is likely to be involved in modulating secondary cell wall biosynthesis in both the Arabidopsis inflorescence stem and seed coat, and that at least some parts of the transcriptional regulatory network in the two tissues are functionally conserved. © 2013 Springer-Verlag Berlin Heidelberg.


Wang S.,Northeast Normal University | Chen J.-G.,Oak Ridge National Laboratory
Frontiers in Plant Science | Year: 2014

MYB transcription factors regulate multiple aspects of plant growth and development. Among the large family of MYB transcription factors, single-repeat R3 MYBs are characterized by their short sequence (<120 amino acids) consisting largely of the single MYB DNA-binding repeat. In the model plant Arabidopsis, R3 MYBs mediate lateral inhibition during epidermal patterning and are best characterized for their regulatory roles in trichome and root hair development. R3 MYBs act as negative regulators for trichome formation but as positive regulators for root hair development. In this article, we provide a comprehensive review on the role of R3 MYBs in the regulation of cell type specification in the model plant Arabidopsis. © 2014 Wang and Chen.


Chen X.-K.,Jilin University | Zou L.-Y.,Jilin University | Guo J.-F.,Northeast Normal University | Ren A.-M.,Jilin University
Journal of Materials Chemistry | Year: 2012

The aromatic diimides are among the most promising and versatile candidates for organic optoelectronic materials due to their commercial availability, low cost, excellent optical and electric performance, such as naphthalene, anthracene and perylene diimides. But, so far, the problem is not clarified - is a five- or six-membered imide ring more helpful for n-type organic semiconductor materials? The work investigated in detail and compared various properties for molecules with a five-/six-membered imide ring from the following aspects: (1) molecular stability, reaction activity, geometries, frontier molecular orbitals as well as oxidation and reduction abilities at the single-molecule level; (2) the variation of transfer integrals at the various molecular stacking motifs; (3) the estimate of carrier mobility and its anisotropy for the actual molecule crystals. The results indicate that molecules with a six-membered imide ring should be more suitable for n-type organic semiconductor materials. This journal is © The Royal Society of Chemistry 2012.


Yu H.-F.,Anshan Normal University | Liao P.-Q.,Northeast Normal University
Gaodeng Xuexiao Huaxue Xuebao/Chemical Journal of Chinese Universities | Year: 2012

Thioacetals are important compounds because they can be considered as both useful protecting groups of carbonyl compounds in the synthesis of multi-functional complex molecules and acyl carbanion equivalents in C-C bond forming reactions. Since many reactions have been developed to prepare oximes from non carbonyl compounds, to lead to a novel and efficient method for thioacetal preparation, transthioacetalization of oximes has received more and more attention. Unfortunately, the transformation usually suffers from the use of harmful, odorous thiols which can lead to serious safety and environment problems. From the green chemistry point of view, an efficient and odorless transthioacetalization of oximes involving an environment friendly reagent is of great importance and necessity. In this work, using odorless and stable α-oxo ketene dithioacetals 1 as thiol equivalents, the thioacetalization reaction of oximes 2 were studied. In the reaction system of MeCOCl-EtOH(95%) or 4-dodecylbenzenesulfonic acid(DBSA)-H 2O, the thioacetalization reaction were carried out in reflux temperature. It is noteworthy that the odor of thiols can not be perceived during either the reaction or workup.


Si Y.,Jilin Agricultural University | Yang G.,Northeast Normal University
Journal of Physical Chemistry A | Year: 2014

We have investigated the chiroptical, linear, and second-order nonlinear optical (NLO) properties of five 1,1,4,4-tetracyanobuta-1,3-diene (TCBD) derivatives and elucidated structure-property relationships from the micromechanism. The experimental UV-vis absorption and circular dichroism (CD) spectra were well reproduced by our calculations at TDB3LYP/6-31+G* level of theory. The electron transition property and chiroptical origin have been assigned and analyzed. The results show that the studied compounds possess large molecular first hyperpolarizabilities, especially for compound 5 which has a value of 35 × 10-30 esu, which is comparable with the measured value for highly π-delocalized phenyliminomethyl ferrocene complex and about 200 times larger than the average first hyperpolarizability of the organic urea molecule. Despite the nonplanarity of these compounds, efficient intramolecular charge transfer (CT) from electron donor to electron acceptor moieties was observed, which plays the key role in determining the NLO response. The intramolecular charge transfer cooperativity was also probed. In view of the first hyperpolarizability values, intrinsic noncentrosymmetric electronic structure, and high stability, the studied compounds have the possibility to be excellent second-order NLO materials. © 2014 American Chemical Society.


Han D.-D.,Jilin Institute of Chemical Technology | Han D.-D.,Northeast Normal University | Lu D.-Y.,Jilin Institute of Chemical Technology | Sun X.-Y.,Jilin Institute of Chemical Technology
Journal of Alloys and Compounds | Year: 2013

The influence of donor and acceptor co-doping on structure and dielectric properties of (Ba1-xNdx) (Ti1-yFe y)O3 (BNTF) (x = 0.05, y = 0.01-0.07; and x = 0-0.08, y = 0.05) ceramics was investigated with X-ray diffraction (XRD), scanning electron microscopy (SEM), electron paramagnetic resonance (EPR), Raman spectroscopy, and dielectric measurements. When x < y, two types of Nd3+ - Fe 3+ and Fe3+ - VO - Fe3+ defect complexes formed and could not coexist, leading to the mixed phases of cubic and hexagonal. A single-phase ceramic with a cubic or tetragonal structure formed for x ≥ y and the dielectric-peak temperature (Tm) in BNTF with x = 0.05 decreased linearly with increasing y at a rate of -5 °C/mol% Fe ions. A high-k Y5V behavior can be realized at x = y = 0.05 (i.e., C-N5F5). The same concentrations of Nd3+ and Fe3+ formed Nd3+ - Fe3+ complexes, which could effectively suppress the dielectric loss and silence the 840 cm-1 band called "Raman charge effect" associated with Nd3+ donors. C-N5F5 exhibited a cubic structure, medium-sized grains (3.3 μm), low dielectric loss (<0.06), and high-k Y5V behavior (ε′RT = 6790). Defect chemistry associated with structure evolution is discussed. © 2013 Elsevier B.V. All rights reserved.


Sun H.,Nanyang Technological University | Shen X.,Nanyang Technological University | Yao L.,Nanyang Technological University | Xing S.,Northeast Normal University | And 3 more authors.
Journal of the American Chemical Society | Year: 2012

We demonstrate a unique capability in partially oxidizing the oligoaniline shell on gold nanoparticles to polyaniline. Because of the solubility difference, the unreacted inner shell section can be selectively dissolved by 2-propanol, giving yolk-shell nanostructures and, thus, making it possible for assessing the oxidized section. The ionic diffusion through the polymer shell is found to be the rate-determining step in the overall process. Conservative estimates show that the diffusion coefficient of AuCl 4 - is at least 700 times slower than that of the typical rate values in traditional studies. It is most likely caused by the lack of micropores in the polymer structures. Such mircopores are hard to avoid in preparing polymer membranes by casting or drying of polymers dissolved in organic solvents. We can rule out the presence of irregular pores on the basis of the uniformly oxidized shell section. With the nanoscale shells, the system is sensitive enough to detect minute changes in the shell or small differences among the individual nanoparticles. Even with a small increase in porosity, for example, when the polyaniline shell is swollen using small amounts of DMF (3%, 5%, or 10% in aqueous solutions), the diffusion coefficient of AuCl 4 - increases to 4, 11, and 17 times, respectively. Thus, our study demonstrates a new methodology for studying the diffusion of ions in hydrophobic polymers. © 2012 American Chemical Society.


Li L.-S.,Northeast Normal University
Monthly Notices of the Royal Astronomical Society | Year: 2013

The secular influence of the time variation of the gravitational constant and solar mass-loss on near-Earth asteroids (NEAs) is examined using the method of celestialmechanics with variable mass and variable gravitational constant. Numerical solutions for the secular variables of the semimajor axes and orbital periods have been given by means of the method of average values for five NEAs. The orbital semimajor axes and periods increase continuously with time. Eccentricities also increase continuously with time. There is no variation in the longitude of perihelion. The results are discussed and conclusions drawn. © 2013 The Author. Published by Oxford University Press on behalf of the Royal Astronomical Society.


Chen X.-K.,Jilin University | Guo J.-F.,Northeast Normal University | Zou L.-Y.,Jilin University | Ren A.-M.,Jilin University | Fan J.-X.,Jilin University
Journal of Physical Chemistry C | Year: 2011

The effects of the pyrazine ring on the geometrical and electronic structures, molecular stacking motifs, carrier injection, and transport properties as well as electronic band structures for some typical molecules with pyrazines (such as tetracene, pentacene, and π-extended tetrathiafulvalene derivatives) were theoretically investigated by quantum chemical methods. The introduction of pyrazine does not affect the molecular planarity and in the meantime largely decreases the energies of the highest occupied molecular orbitals and the lowest unoccupied molecular orbitals and hence improves their stability in air and ability of electron injection. More important, it is very helpful for prompting the molecular π-stacking. Small electron reorganization energies and large electronic coupling originated from their dense π-stacking give rise to their excellent electron transport properties, which makes them become a class of promising candidates for excellent n-type organic field-effect transistor (OFET) materials. So introducing pyrazine is an effective approach to obtain the excellent n-type OFET materials. © 2011 American Chemical Society.


Yan K.,Jilin University | Xu X.,Jilin University | Liu X.,Jilin University | Wang X.,University of Manitoba | And 2 more authors.
Pediatric Blood and Cancer | Year: 2015

Background: Although genetic and environmental factors are considered to be the main causes of acute lymphoblastic leukemia, the associations between maternal factors during pregnancy and the childhood ALL is still unclear. Procedure: In this study, meta-analysis was used. Medline, PubMed, and Web of Science were searched. The result was assessed based on pooled odds ratios (ORs) with 95% confidence intervals (CIs). Results: The pooled ORs showed that there were associations between childhood ALL and the birth order (The first vs others, OR=1.08, 95%CI=1.00-1.16), the education of pregnant woman (>high school vs ≤high school, OR=0.82, 95%CI=0.77-0.86), smoking (Ever vs never, OR=1.10, 95%CI=1.02-1.19). Conclusions: Our meta-analysis showed that there were important associations between childhood ALL and the birth order, the education of pregnant woman, smoking. Pediatr Blood Cancer 2015;62:1162-1170. © 2015 Wiley Periodicals, Inc.


Zhong S.,Northeast Normal University
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) | Year: 2016

Based on the common misunderstandings and connotation of educational informationization as well as the value appeal of education reform, this paper puts forward the basic idea of innovative teaching, and promotes education fairness by the integration of information technology and subject teaching. Specific ways and methods are proposed. Evaluation is conducted, and the effectiveness of a digital learning environment is analyzed. © Springer International Publishing Switzerland 2016.


Wang C.L.,Northeast Normal University | Kang Z.H.,Jilin University | Tian S.C.,Jilin University | Wu J.H.,Jilin University
Optics Express | Year: 2012

We demonstrate coherent control of spontaneous emission from an indirectly coupled transition in a microwave driven four-level atomic system. The transition of concern is not directly coupled by any laser fields, while the ground state is coupled to another ground state by a microwave field. We show that the coupling of the microwave field produces interesting features such as double narrow lines in the emission spectrum. The heights, widths and positions of the emission peaks can be controlled by modifying the Rabi frequency and detuning of the microwave field. We discuss the spectra in the dressed states basis. © 2012 Optical Society of America.


Liu W.,Binzhou University | Li M.,Binzhou University | Gao K.,Binzhou University | Gu D.,Northeast Normal University
Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment | Year: 2014

We investigate the discharge characteristics of a penning ion source for a compact sealed neutron generator in DC mode. A measuring system consisting of console, vacuum gauges, and teslameter is established. By using the measuring system, the discharge current as a function of ion source voltage, gas pressure, and magnetic field is studied. The results show that the neutron generator can operate in a safe and steady state when the experimental parameters are as follows: ion source voltage of 1.2-2 kV, gas pressure of 4×10-2-8×10-2 Pa, and magnetic field of 0.3-0.5 T. Within these ranges, the neutron yield of the generator can reach 2×108 n/s. © 2014 Elsevier B.V. All rights reserved.


Li J.,Northeast Normal University | Sasaki O.,Niigata University
Applied Optics | Year: 2011

A sinusoidally vibrating interference pattern (SVIP) is used as an exact spatial scale in order to measure a cross-sectional profile of a thread gauge. The SVIP is projected on the thread gauge surface, and lights diffracted and reflected from the end points of the thread gauge surface are extracted by spatial frequency filteringinan imaging system to makean image of the end points whose positions are decidedby the peak positions of amplitude distributions in the image. The coordinates of the end points or the cross-sectional profile of the thread gauge is obtained from the phases measured at the positions of the end points, phase distribution of the SVIPon aCCD image sensor, and the pixel positions of the CCD image sensor. © 2011 Optical Society of America.


The fibroblast growth factors (FGFs) are important for embryo development, wound healing, hematopoiesis, and angiogenesis. FGF-1, a member of FGF family, is involved in both receptor-dependent pathways and an intracrine pathway. Studies have recently shown that FGF-1 is overexpressed in the early stages of several kinds of cancer. Thus, FGF-1 is a candidate for cancer immunotargeting. To study the potential use of therapeutic antibodies against FGF-1, a monoclonal hybridoma 1C9 secreting monoclonal antibody specific for FGF-1 was developed. Then, a single-chain variable fragment (scFv) antibody was genetically engineered from hybridama 1C9. The binding of the scFv1C9 to the antigen FGF-1 was demonstrated by ELISA and immunoprecipitation assays. Functional analysis showed that the overexpressed scFv1C9 in MCF-7 cells targeted endogenous FGF-1 and prevented the translocation of FGF-1 into the nucleus, resulting in the blockade of the intracrine pathway of FGF-1, which caused the G1 arrest by p21 up-regulation. These results suggest that the generated scFv1C9 is an effective inhibitor of the intracrine pathway of FGF-1 and has a potential application as anti-tumoral agent in breast cancer. Copyright © 2011 Wiley Periodicals, Inc.


Gong J.,Georgia Institute of Technology | Gong J.,Northeast Normal University | Li Y.,Georgia Institute of Technology | Hu Z.,Georgia Institute of Technology | And 2 more authors.
Journal of Physical Chemistry C | Year: 2010

In this communication, we reported for the first time an ultrasensitive nanostructrued sensor that can detect 50 ppt of NH3 gas in air. Specifically, nanograins of a p-type conductive polymer, polyaniline (PANI), are enchased on an electrospun n-type semiconductive TiO2 fiber surface. The resistance of the p-n heterojunctions combining with the bulk resistance of PANI nanograins can function as electric current switches when NH3 gas is absorbed by PANI nanoparticles. As a result, the sensor sensitivity can be significantly improved. The sensor fabricated in this work is 1000 times more sensitive than the best PANI sensor reported in the literature. © 2010 American Chemical Society.


A neutral polysaccharide fraction (WGPN) prepared from Panax ginseng C.A. Meyer by hot water extraction and DEAE-cellulose chromatography was tested for its anticancer activity alone and in combination with 5-fluorouracil (5-FU) in Sarcoma-180 (S180) tumor-bearing mice by intragastric administration. WGPN alone inhibited S180 tumor growth in a bell-shaped dose-response curve, and the combination with 5-FU showed a synergistic effect. Studies of various immunological activities in S180-bearing mice revealed that WGPN stimulated the proliferation of lymphocytes, increased natural killer cell cytotoxicity, enhanced the phagocytosis and nitric oxide production by macrophages, and increased the level of tumor necrosis factor-alpha in serum. In combination with 5-FU, WGPN mitigated damage to the immune system caused by 5-FU in S180-bearing mice. These results suggest that WGPN might be a potential adjuvant for chemotherapeutic drugs.


He M.,South China Normal University | Zhang S.-J.,Northeast Normal University
Journal of Pragmatics | Year: 2011

The present study adopts a new approach to face-analysis, originally proposed by Spencer-Oatey (2007:639-656) in light of identity theories, to analyze and re-conceptualize the Chinese concept of face based on data collected from a modern Chinese TV drama. The results reveal that miànzi in Chinese culture is inherently associated with the respectable identity and/or status that an individual establishes, and many Chinese miànzi phenomena can be explained and understood in terms of people's attributes or characteristics from a miànzi-sensitive perspective on identity theory. Its findings also indicate that Chinese people tend to be miànzi-sensitive about those attributes or characteristics foregrounded in social interactions of their own, as well as those of their family members, close friends, colleagues, and social groups. Based on these categories of miànzi-sensitive factors, this paper concludes that the Chinese concept of face, as a holistic term, can be categorized as individual, relational, and group miànzi. © 2011 Elsevier B.V.


Wu Y.,Heilongjiang Institute of Science and Technology | Xing S.,Northeast Normal University | Fu J.,Heilongjiang Institute of Science and Technology
Journal of Applied Polymer Science | Year: 2010

Polypyrrole/Titanium dioxide (PPy/TiO2) composite thin films were prepared by polymerizing the monomer pyrrole in aqueous solution containing a certain amount of TiO2 particles at room temperature, and their response to ammonia (NH3) gas was examined systematically. Compared with the pristine PPy film, which reached the saturation at the concentration of NH3 beyond 200 ppm, the composite films showed more stable response and higher sensitivity. Furthermore, the PPy/TiO2 composite thin films exhibited a low detection limit of 2 ppm. The film thickness, which had a strong influence on the film sensitivity to NH3, could be controlled by varying the polymerization time. The sensitivity to NH3 gas of the samples with different content of TiO2 and different molar ratio of PPy/TiO2/oxidant was studied. © 2010 Wiley Periodicals, Inc.


Mao C.,CAS Changchun Institute of Applied Chemistry | Mao C.,University of Chinese Academy of Sciences | Huang J.,CAS Changchun Institute of Applied Chemistry | Huang J.,University of Chinese Academy of Sciences | And 4 more authors.
Journal of Physical Chemistry Letters | Year: 2013

We present a simple but efficient route to prepare a highly anisotropic conductive plastic thin film from the polypropylene/(styrene-ethylene/butadiene- styrene) triblock copolymer/graphene blend via shear-induced self-assembly. Under the shear-flow induction, GE nanosheets dispersed in the polymer matrix can spontaneously assemble into ordered parallel stripes, which endow the materials significantly conductive anisotropy. The electrical resistivity in the direction parallel to the graphene stripes is almost four orders of magnitude lower than that which is perpendicular to the stripes. This study provides a new method for the precise control of the organization of functional nano-objects in polymer matrix, which can be widely extended to the fabrication of other multifunctional anisotropic materials of interest in various fields. © 2012 American Chemical Society.


Gong J.,Georgia Institute of Technology | Gong J.,Northeast Normal University | Li Y.,Georgia Institute of Technology | Li Y.,Dalian University of Technology | Deng Y.,Georgia Institute of Technology
Physical Chemistry Chemical Physics | Year: 2010

In this communication, we report that the depletion zone thickness of the p-n junction between an n-type ZnO and a p-type polyaniline could be controlled by UV and visible light illumination. Based on this princile, photoresponsive sensors were constructed by combining polyaniline thin film and ZnO nanorods. Different from pure ZnO nanomaterials whose conductivity increases when they are exposed to UV illumination, the conductivity of the photoresponsive sensor studied in this communication decreased when the UV light was turned on. The surface modification of ZnO could switch the wavelength of the response light from UV to visible light. © the Owner Societies 2010.


Wang X.,Northeast Normal University | Navasca C.,University of Alabama at Birmingham
Proceedings of the IEEE International Conference on Computer Vision | Year: 2016

In this paper, we propose a novel framework for finding low rank approximation of a given tensor. This framework is based on the adaptive lasso with coefficient weights for sparse computation in tensor rank detection. We also provide an algorithm for solving the adaptive lasso model problem for tensor approximation. In a special case, the convergence of the algorithm and the probabilistic consistency of the sparsity have been addressed [15] when each weight equals to one. The method is applied to background extraction and video compression problems. © 2015 IEEE.


Liu H.,Jilin University | Liu L.,Jilin University | Zhang H.,Northeast Normal University
Journal of Biomedical Informatics | Year: 2010

Selecting relevant and discriminative genes for sample classification is a common and critical task in gene expression analysis (e.g. disease diagnostic). It is desirable that gene selection can improve classification performance of learning algorithm effectively. In general, for most gene selection methods widely used in reality, an individual gene subset will be chosen according to its discriminative power. One of deficiencies of individual gene subset is that its contribution to classification purpose is limited. This issue can be alleviated by ensemble gene selection based on random selection to some extend. However, the random one requires an unnecessary large number of candidate gene subsets and its reliability is a problem. In this study, we propose a new ensemble method, called ensemble gene selection by grouping (EGSG), to select multiple gene subsets for the classification purpose. Rather than selecting randomly, our method chooses salient gene subsets from microarray data by virtue of information theory and approximate Markov blanket. The effectiveness and accuracy of our method is validated by experiments on five publicly available microarray data sets. The experimental results show that our ensemble gene selection method has comparable classification performance to other gene selection methods, and is more stable than the random one. © 2009 Elsevier Inc. All rights reserved.


Li G.,Jilin University | Zhu D.,Northeast Normal University | Peng T.,Jilin University | Liu Y.,Jilin University | And 2 more authors.
Advanced Functional Materials | Year: 2014

Two phosphorescent iridium complexes with bipolar transporting ability, namely FPPCA (500 nm) and BZQPG (600 nm), are synthesized and employed as an ideal host-guest system for phosphorescent organic light emitting diodes (PHOLEDs).The devices give very high-efficiency orange-red emission from BZQPG with maximum external quantum efficiency (EQE orext) of >27% and maximum power efficiency (PE or ηp) of >75 lm/W, and maintain high levels of 26% and 55 lm/W, 25% and 40 lm/W at high luminance of 1000 and 5000 cd m-2, respectively, within a range of 8-15 wt% of BZQPG. The realization of such high and stable EL performance results from the coexistence of two parallel paths: i) effective energy transfer from host (FPPCA) to guest (BZQPG) and ii) direct exciton formation on the BZQPG emitter, which can alternately dominate the electrophosphorescent emission. This all-phosphor doping system removes the charge-injection barrier from the charge-transport process to the emissive layer (EML) due to the inherent narrow E g of both phosphors. Therefore, this ideal host-guest system represents a new design to produce PHOLEDs with high efficiency and low efficiency roll-off using a simple device configuration. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


Hu L.,Lund University | Hu L.,Northeast Normal University | Soderhjelm P.,Lund University | Ryde U.,Lund University
Journal of Chemical Theory and Computation | Year: 2013

We here suggest and test a new method to obtain stable energies in proteins for charge-neutral reactions by running large quantum mechanical (QM) calculations on structures obtained by combined QM and molecular mechanics (QM/MM) geometry optimization on several snapshots from molecular dynamics simulations. As a test case, we use a proton transfer between a metal-bound cysteine residue and a second-sphere histidine residue in the active site of [Ni,Fe] hydrogenase, which has been shown to be very sensitive to the surroundings. We include in the QM calculations all residues within 4.5 Å of the active site, two capped residues on each side of the active-site residues, and all charged groups that are buried inside the protein, which for this enzyme includes three iron-sulfur clusters, in total, 930 atoms. These calculations are performed at the BP86/def2-SV(P) level, but the energies are then extrapolated to the B3LYP/def2-TZVP level with a smaller QM system, and zero-point energy, entropy, and thermal effects are added. We test three approaches to model the remaining atoms of the protein solvent, viz., by standard QM/MM approaches using either mechanical or electrostatic embedding or by using a continuum solvation model for the large QM systems. Quite encouragingly, the three approaches give the same results within 14 kJ/mol, and variations in the size of the QM system do not change the energies by more than 8 kJ/mol, provided that the QM/MM junctions are not moved closer to the QM system. The statistical precision for the average over 10 snapshots is 1-3 kJ/mol. © 2012 American Chemical Society.


Sun L.,Jilin University | Xing H.,Northeast Normal University | Xu J.,Jilin University | Liang Z.,Jilin University | And 2 more authors.
Dalton Transactions | Year: 2013

A novel metal-organic framework [Cd3(CPEIP)2(DMF) 3]·solvent (1) based on a neutral non-oxo triangular [Cd 3(COO)6] secondary building unit (SBU), was synthesized under solvothermal conditions by using a rigid unsymmetrical tricarboxylate ligand 5-((4-carboxyphenyl)ethynyl)isophthalic acid (H3CPEIP). Single-crystal X-ray diffraction analysis reveals that compound 1 crystallizes in the monoclinic space group C2/c. The crystal structure exhibits a rare (3,3,6)-connected three-dimensional (3-D) framework with vertex symbol of (42.6)(43)(45.64.86). The incorporation of CPEIP3+ into 1 gives rise to high luminescence in solid state. The emission of micrometer-sized compound 1 (1′) dispersed in ethanol could be quenched efficiently by picric acid (PA), indicating that this compound could be utilized as a chemosensor for detection of aromatic explosives. © 2013 The Royal Society of Chemistry.


Xu X.,Liaoning University | Zhang X.,Liaoning University | Liu X.,Liaoning University | Sun T.,Liaoning University | Wang E.,Northeast Normal University
Crystal Growth and Design | Year: 2010

A unique three-dimensional metal-organic framework (MOF) [Cd 4(1,10'-phen)(fum)(S-mal)(R-mal)(H2O)] (1) (1,10'-phen =1,10-phenanthroline, fum = fumarate dianion, mal = malate dianion) has been synthesized and characterized by single-crystal X-ray analysis. Under hydrothermal conditions, after a "three birds with one stone" in situ reaction process, maleic acid turns into fumarate dianion, isomeric R-malate dianion and S-malate dianion, which further connect with Cd atoms and form an octanuclear Cd cluster. The octanuclear Cd cluster links with neighboring clusters and constructs a rod-shaped secondary building unit (SBU). Neighboring rod-shaped SBUs are further connected by fumarate dianions and thus forms a three-dimensional network. To our interests, complex 1 exhibits interesting semiconductivity and fluorescence properties. When citraconic acid was used instead of maleic acid, a new complex [Cd2(mesac)2(1,10'- phen)2] (2) (mesac = mesaconate dianion) was synthesized under about the same reaction conditions. Complex 2 also exhibits fluorescence properties. © 2010 American Chemical Society.


Yang H.T.,Northeast Normal University
Journal of Physics Condensed Matter | Year: 2011

We prove that the strain induced shift of the Dirac points in graphene is a curl field if the strain is nonuniform. This curl field provides a geometrical explanation of the strain induced pseudo-magnetic field. We also prove that the Dirac points must be confined within two triangles, each one having one-eighth the area of the Brillouin zone. © 2011 IOP Publishing Ltd.


Jain T.,Copenhagen University | Tang Q.,Northeast Normal University | Bjornholm T.,Copenhagen University | Norgaard K.,Copenhagen University
Accounts of Chemical Research | Year: 2014

A central challenge in molecular electronics is to create electrode pairs separated by only a few nanometers that can accommodate a single molecule of interest to be optically or electrically characterized while residing in the gap. Current techniques for nanogap fabrication are largely based on top-down approaches and often rely on subsequent deposition of molecules into the nanogap. In such an approach, the molecule may bridge the gap differently with each experiment due to variations at the metal-molecule interface. Conversely, chemists can readily synthesize gold nanorods (AuNRs) in aqueous solution. Through controlled end-to-end assembly of the AuNRs into dimers or chains, facilitated via target molecules, they can be used as electrical contacts. In this way, the preparation of AuNR-molecule-AuNR junctions by wet chemical methods may afford a large number of identical devices with little variation in the interface between molecule and electrode (AuNR).In this Account, we highlight recent progress in using chemically synthesized AuNRs as building blocks for molecular electronic applications. We outline the general synthesis and properties of AuNRs and describe the aqueous growth of dimeric AuNR structures from an insulating molecule linked to AuNR precursors (gold seeds). Conjugated, electronically active molecules are typically not soluble under the conditions required for the bottom-up growth of AuNRs. Therefore, we present a strategy that utilizes host-guest chemistry in order to make such π-systems compatible with the AuNR growth procedure. In order to electrically characterize the AuNR-molecule-AuNR constructs, we must transfer them onto a substrate and contact external electrodes. We discuss the implications of using electron-beam lithography for making this contact. In addition, we introduce a novel fabrication approach in which we can grow AuNR nanogap electrodes in situ on prepatterned substrates, thus circumventing post-processing steps that potentially damage the nanogap environment. Due to the inherent optical properties of AuNRs, electromagnetic field enhancement in the nanogaps lets us spectroscopically characterize the molecules via surface-enhanced Raman scattering. We discuss the incorporation of oligopeptides functionalized with acetylene units having uniquely identifiable vibrational modes. This acetylene moiety allows chemical reactions to be performed in the gaps via click chemistry, and the oligopeptide linking platform opens for integration of larger biological components. © 2013 American Chemical Society.


Wang X.,Beijing University of Chemical Technology | Chen W.,Beijing University of Chemical Technology | Song Y.-F.,Beijing University of Chemical Technology | Song Y.-F.,Northeast Normal University
European Journal of Inorganic Chemistry | Year: 2014

The directional self-assembly of exfoliated layered europium hydroxide (LEuH) nanosheets and europium-containing heteropolytungstate anions has been achieved by mixing an LEuH colloidal solution and a Na9EuW 10O36·32H2O (EuW10) solution at room temperature leading to the formation of a new inorganic/inorganic hybrid material, Eu2(OH)5(EuW10O36) 0.11·5.5H2O (LEuH-EuW10). The use of LEuH-EuW10 in extractive catalytic oxidative desulfurization (ECODS) showed that highly efficient and selective deep desulfurization can be achieved in only 15 min under mild conditions. A maximum turnover number (TON) of around 1600 has been achieved. In addition, the catalyst can be recycled and reused at least 10 times with only a slight loss of catalytic efficiency. The self-assembly of exfoliated layered europium hydroxides (LEuH) and Na 9EuW10O36·32H2O (EuW 10) led to a new inorganic/inorganic hybrid material, LEuH-Euw 10. The use of LEuH-EuW10 in extractive catalytic oxidative desulfurization showed that this catalyst is highly efficient and selective for the deep desulfurization of dibenzothiophene in the presence of H2O2 and [omim]PF6 under mild conditions. Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


An H.,Dalian University of Technology | Zhang H.,Dalian University of Technology | Chen Z.,Dalian University of Technology | Li Y.,Northeast Normal University | And 2 more authors.
Dalton Transactions | Year: 2012

Six 3D architectures based on lanthanide-substituted polyoxometalosilicates, KLn[(H 2O) 6Ln] 2[(H 2O) 4LnSiW 11O 39] 2· nH 2O (Ln = La 1, n = 42; Ce 2, n = 40), H[(H 2O) 6Nd] 2[(H 2O) 7Nd][(H 2O) 4NdSiW 11O 39][(H 2O) 3NdSiW 11O 39]·13H 2O (3), H 2K 2[(Hpic)(H 2O) 5Ln] 2[(H 2O) 4LnSiW 11O 39] 2·nH 2O (Ln = La 4, n = 18.5; Ce 5, n = 35; Nd 6, n = 36; Hpic = 4-picolinic acid), have been synthesized and characterized by elemental analysis, IR and UV-vis spectroscopy, TG analysis, powder X-ray diffraction and single crystal X-ray diffraction. Compounds 1 and 2 are isostructural, built up of lanthanide-substituted polyoxoanions [{(H 2O) 4Ln(SiW 11O 39)} 2] 10- linked by Ln 3+ cations to form a 3D open framework with 1D channels. The polyoxoanion [{(H 2O) 4Ln(SiW 11O 39)} 2] 10- consists of two α 1-type mono-Ln-substituted Keggin anions. When Nd 3+ ion was used instead of La 3+ or Ce 3+ ions, compound 3 with a different structure was obtained, containing two kinds of polyoxoanions [{(H 2O) 4Nd(SiW 11O 39)} 2] 10- and [{(H 2O) 3Nd(SiW 11O 39)} 2] 10- which are connected together by Nd 3+ ions to yield a 3D framework. When 4-picolinic acid was added to the reaction system of 1-3, isostructural compounds 4-6 were obtained, constructed from the polyoxoanions [{(H 2O) 4Ln(SiW 11O 39)} 2] 10- linked by picolinate-chelated lanthanide centers to form a 3D channel framework. From a topological viewpoint, the 3D nets of 1, 2, 4, 5 and 6 exhibit a (3,6)-connected rutile topology, whereas the 3D structure of 3 possesses a rare (3,3,6,10)-connected topology. The magnetic properties of 2, 3, 5 and 6 have been studied by measuring their magnetic susceptibilities in the temperature range 2-300 K. © The Royal Society of Chemistry 2012.


Si Y.,Jilin Agricultural University | Yang G.,Northeast Normal University
RSC Advances | Year: 2013

The chiroptical, linear, and second-order nonlinear optical (NLO) properties of chiral mononuclear and dinuclear zinc complexes have been investigated for the first time at density functional theory level. The calculated electron absorption energies and oscillator strengths are in reasonable agreement with the experimental ones. The good agreement between the experimental and the simulated CD spectra shows that TDDFT calculations can be used to assign the absolute configurations (ACs) of chiral zinc complexes with high confidence. Based on these calculated results, the electron transition property and chiroptical origin have been analyzed and assigned. The results show that the coordinated Zn atoms have certain effects on the chiroptical property. The larger nonlinear optical response mainly results from interligand and intraligand charge transfer. The studied complexes have a possibility to be excellent second-order nonlinear optical material from the standpoint of first hyperpolarizability value, transparency and intrinsic non-centrosymmetric electronic structure. © 2013 The Royal Society of Chemistry.


Li M.,University of Chinese Academy of Sciences | Xu C.,University of Chinese Academy of Sciences | Ren J.,University of Chinese Academy of Sciences | Wang E.,Northeast Normal University | Qu X.,University of Chinese Academy of Sciences
Chemical Communications | Year: 2013

Herein we report that POMs can not only inhibit Aβ aggregation but also photodegrade Aβ, especially the oligomers, showing enhanced inhibition effects. © 2013 The Royal Society of Chemistry.


Wang Y.,Jilin University | Li M.,Jilin University | Zhang Y.,Jilin University | Yang J.,Northeast Normal University | And 5 more authors.
Chemical Communications | Year: 2013

Stress has been proved to acidulate amphoteric molecules and promote an intermolecular proton transfer, which results in a significant absorption and emission change. The stress acidulated amphoteric molecules open a new avenue for developing mechanochromic materials and anticipate many broad applications such as stress/pressure sensors and rewritable media. © 2013 The Royal Society of Chemistry.


Zeng T.,CAS Research Center for Eco Environmental Sciences | Zhang X.,CAS Research Center for Eco Environmental Sciences | Zhang X.,Hebei United University | Wang S.,Northeast Normal University | And 3 more authors.
Journal of Materials Chemistry A | Year: 2013

A facile method is proposed to fabricate yolk-shell microspheres consisting of a movable silica core, a multifunctional double-layered shell, and plenty of tiny gold nanoparticles (Au NPs, ∼2 nm) confined within the interior cavity and the mesoporous shell. The presented strategy involves the one-step coating of a Fe3O4/carbon double-layered shell, the partial etching of the silica cores and the in situ immobilization of Au NPs. The inner Fe3O4 layer of the double-layered shell endows the composites with superparamagnetism and thereby simplifies the introduction procedure of a magnetic component. The outer carbon layer not only protects the Fe3O4 layer from outside harsh conditions but also provides additional adsorption sites for Au NPs besides the interior space. The large number of catalytic active sites together with the advantages of the yolk-shell architecture make the nanocomposite a perfect catalyst for the reduction of 4-nitrophenol to 4-aminophenol in the presence of NaBH4 (TOF value is 17.4 min-1). Moreover, the synthesized catalyst can be easily recovered and reused for at least nine cycles due to its magnetically separable feature and good stability. These confirm that the as-prepared yolk-like nanocomposites are promising candidates for catalytic application. © 2013 The Royal Society of Chemistry.


Dong M.-Y.,Beijing Normal University | Jiang Y.,Beijing Normal University | Zhang D.-Y.,Beijing Normal University | Wu Z.-F.,Northeast Normal University
Theoretical and Applied Climatology | Year: 2013

Daily mean air temperatures from 81 meteorological stations in Northeast China were analyzed for the spatiotemporal change of the climatic growing season during the period 1960-2009. Our results showed that latitude strongly influenced the spatial patterns of the mean start (GSS), end (GSE), and length (GSL) of the growing season. For the area studied, a significant increasing trend in GSL during 1960-2009 was detected at a significance level of 0. 01, especially after the early 1980s. The area-average GSL has extended 13. 3 days during the last 50 years, mainly due to the advanced GSS evident in the spring (7. 9 days). The variations of GSS and GSE were closely correlated with the monthly mean temperature (Tmean) of April and October, respectively, while GSL was closely related to the monthly minimum temperatures (Tmin) of spring (March to April) and autumn (September to October). The distributions of the trends in growing season parameters (GSS, GSE, and GSL) showed great spatial variability over Northeast China. Significant relationships between altitude and the trend rates of the GSS and GSL were detected, while geographic parameters had little direct effect on the change in GSE. This extended growing season may provide favorable conditions for agriculture and forest, and improve their potential production. © 2012 Springer-Verlag.


Jiang C.,Huaiyin Normal University | Liu H.,Huaiyin Normal University | Liu H.,Northeast Normal University | Cui Y.,Huaiyin Normal University | And 3 more authors.
Optics Express | Year: 2013

We theoretically demonstrate the mechanically mediated elec-tromagnetically induced transparency in a two-mode cavity optomechanical system, where two cavity modes are coupled to a common mechanical resonator. When the two cavity modes are driven on their respective red sidebands by two pump beams, a transparency window appears in the probe transmission spectrum due to destructive interference. Under this situation the transmitted probe beam can be delayed as much as 4 μs, which can be easily controlled by the power of the pump beams. © 2013 Optical Society of America.


Yang G.Z.,Sun Yat Sen University | Song H.W.,Sun Yat Sen University | Cui H.,Sun Yat Sen University | Liu Y.C.,Northeast Normal University | Wang C.X.,Sun Yat Sen University
Nano Energy | Year: 2013

Ultrafast rechargeable lithium-ion batteries made from low-cost and abundant electrode materials would satisfy the increasing demands for energy storage worldwide. Herein, we demonstrate a large-scale hierarchical bottom-up assembly route for the formation of lithium-ion battery anode with excellent electrochemical properties by creating composites based on embedding ZnO nanoparticles into nanocarbon matrix which uniformly dispersed on the outer and inner surfaces of a porous creased carbon bubble host, which serves to hold them tightly by the pores and creases during battery operation and sandwich them between rapid ion and electron transport pathways. We successfully increase the charging and discharging rates by nearly 300-fold over the highest rate yet reported while attaining high power density and energy density which represents the best performance for long-cycle ZnO anode so far.© 2013 Elsevier Ltd.


Liu X.,Northeast Normal University
ESAIM - Control, Optimisation and Calculus of Variations | Year: 2014

This paper is addressed to proving a new Carleman estimate for stochastic parabolic equations. Compared to the existing Carleman estimate in this respect (see [S. Tang and X. Zhang, SIAM J. Control Optim. 48 (2009) 2191-2216.], Thm. 5.2), one extra gradient term involving in that estimate is eliminated. Also, our improved Carleman estimate is established by virtue of the known Carleman estimate for deterministic parabolic equations. As its application, we prove the existence of insensitizing controls for backward stochastic parabolic equations. As usual, this insensitizing control problem can be reduced to a partial controllability problem for a suitable cascade system governed by a backward and a forward stochastic parabolic equation. In order to solve the latter controllability problem, we need to use our improved Carleman estimate to establish a suitable observability inequality for some linear cascade stochastic parabolic system, while the known Carleman estimate for forward stochastic parabolic equations seems not enough to derive the desired inequality. © EDP Sciences, SMAI 2014.


Li L.-S.,Northeast Normal University
Research in Astronomy and Astrophysics | Year: 2015

This paper provides a method to study the solution of equations for synchronous binary stars with large eccentricity on the main sequence. The theoretical results show that the evolution of the eccentricity is linear with time or follows an exponential form, and the semi-major axis and spin vary with time in an exponential form that are different from the results given in a previous paper. The improved method is applicable in both cases of large eccentricity and small eccentricity. In addition, the number of terms in the expansion of a series with small eccentricity is very long due to the series converging slowly. The advantage of this method is that it is applicable to cases with large eccentricity due to the series converging quickly. This paper chooses the synchronous binary star V1143 Cyg that is on the main sequence and has a large eccentricity (e = 0.54) as an example calculation and gives the numerical results. Lastly, the evolutionary tendency including the evolution of orbit and spin, the time for the speed up of spin, the circularization time, the orbital collapse time and the life time are given in the discussion and conclusion. The results shown in this paper are an improvement on those from the previous paper. © 2015 National Astronomical Observatories, Chinese Academy of Sciences and IOP Publishing Ltd.


Chen Z.,Northeast Normal University
Molecular Metabolism | Year: 2016

Background: Long noncoding RNAs (lncRNAs) are a novel group of universally present, non-coding RNAs (>200 nt) that are increasingly recognized as key regulators of many physiological and pathological processes. Scope of review: Recent publications have shown that lncRNAs influence lipid homeostasis by controlling lipid metabolism in the liver and by regulating adipogenesis. lncRNAs control lipid metabolism-related gene expression by either base-pairing with RNA and DNA or by binding to proteins. Major conclusions: The recent advances and future prospects in understanding the roles of lncRNAs in lipid homeostasis are discussed. © 2015 The Author.


Liu M.,Harbin Institute of Technology | Wang K.,Harbin Institute of Technology | Wang K.,Northeast Normal University
Journal of Theoretical Biology | Year: 2010

This is a continuation of our paper [Liu, M., Wang, K., 2010. Persistence and extinction of a stochastic single-specie model under regime switching in a polluted environment, J. Theor. Biol. 264, 934-944]. Taking both white noise and colored noise into account, a stochastic single-species model under regime switching in a polluted environment is studied. Sufficient conditions for extinction, stochastic nonpersistence in the mean, stochastic weak persistence and stochastic permanence are established. The threshold between stochastic weak persistence and extinction is obtained. The results show that a different type of noise has a different effect on the survival results. © 2010 Elsevier Ltd.


Liu C.-G.,Northeast Dianli University | Liu C.-G.,Northeast Normal University | Liu C.-G.,CAS Changchun Institute of Applied Chemistry | Guan X.-H.,Northeast Dianli University
Journal of Physical Chemistry C | Year: 2013

The electronic structure and second-order nonlinear optical (NLO) property of a series of monoruthenium-substituted Keggin-type polyoxometalates (POMs) have been studied by using density functional theory (DFT) and time-dependent (TD)DFT calculations. The DFT calculation supports that these POM complexes possess donor-π-conjugated bridge-acceptor (D-π-A) structure, which the ruthenium atom acts as the role of electron donor and the three vanadium atoms in cap region of Keggin-type POM act as the role of electron acceptor. It is well-known that D-π-A structure, as a simple molecular scheme, has been successfully used in the development of organic NLO materials. However, the totally inorganic molecule having D-π-A structure is very rare. Thereby the second-order NLO properties of these POM complexes have been analyzed in this work. According to the calculations, introduction of the electron acceptor leads to a substantial enhancement on the second-order NLO response. The calculated βHRS(-2ω; ω, ω) value of three-vanadium-atom derivative [{PW9V3O39}RuII(H 2O)]8- is 34 times as large as that of [{PW 11O39}RuII(H2O)]5- according to CAM-B3LYP/6-31+g* calculations (Lanl2dz basis sets for metal atom) in acetonitrile. Because of the redox-active ruthenium center and large second-order NLO response, the redox switching of second-order NLO responses for the three-vanadium-atom derivative [{PW9V3O 39}RuII(H2O)]8- also have been studied. The results show that the RuII→RuIII oxidation leads to the first hyperpolarizability to decrease remarkably. © 2013 American Chemical Society.


Sun Z.,Northeast Normal University
Proceedings of the 2011 Chinese Control and Decision Conference, CCDC 2011 | Year: 2011

In this paper, we propose two hybrid conjugate gradient methods, which produce sufficient descent direction at every iteration. The theoretical analysis shows that the algorithm is global convergence under some suitable conditions. The numerical results show that both hybrid algorithms are efficient for the given test problems from the Matlab library. © 2011 IEEE.


Sui J.,Tsinghua University | Sui J.,University of Oxford | Liu M.,Northeast Normal University | Mevorach C.,University of Birmingham | Humphreys G.W.,University of Oxford
Cerebral Cortex | Year: 2013

Perceptual learning is associated with experience-based changes in stimulus salience. Here, we use a novel procedure to show that learning a new association between a self-label and a neutral stimulus produces fast alterations in social salience measured by interference when targets associated with other people have to be selected in the presence of self-associated distractors. Participants associated neutral shapes with either themselves or a friend, over a short run of training trials. Subsequently, the shapes had to be identified in hierarchical (global-local) forms. The data show that giving a shape greater personal significance by associating it with the self had effects on visual selection equivalent to altering perceptual salience. Similar to previously observed effects linked to when perceptually salient distractors are ignored, effects of a self-associated distractor also increased activation in the left intraparietal cortex sulcus. The results show that self-associations to sensory stimuli rapidly modulate neural responses in a manner similar to changes in perceptual saliency. The self-association procedure provides a new way to understand how personal significance affects behavior. © The Author 2013. Published by Oxford University Press.


Xiong Y.,Liaoning University | Lu X.,Northeast Normal University
Journal of Polymer Research | Year: 2010

A series of Rhenium (VII, Re7+) compound-doped polyimide (PI) nanohybrid films had been successfully fabricated from methyltrioxorhenium (MTO) and polyamic acid (PAA) via the solution direct-dispersing method, followed by a stepwise thermal imidization process. X-ray photoelectron spectroscopy (XPS) confirmed that MTO had decomposed into Re (IV) oxidation state (ReO 2). Field emission scanning electron microscopy (FE-SEM) showed that for the differrent hybrid films, the ReO2 nanoparticles which formed by MTO decomposing well dispersed in polyimide matrix with a size of 40-60 nm. Thermal analysis indicated that the introduction of MTO decreased the thermal stability and the glass transition temperature (Tg) because of the unstable MTO. DMTA and static tensile measurements showed that the storage modulus and the elongation at break of nanocomposite films had a maximum value when the 1% of MTO was doped in PI, while the tensile strength decreased with increasing MTO content on the whole. © 2009 Springer Science+Business Media B.V.


Cheng C.-L.,CAS Dalian Institute of Chemical Physics | Cheng C.-L.,Northeast Normal University | Zhao G.-J.,CAS Dalian Institute of Chemical Physics
Nanoscale | Year: 2012

In the present work, we explored the diameter selectivity of dynamic self-assembly for the single-strand DNA (ssDNA) encapsulation in double-walled nanotubes (DWNTs) via molecular dynamics simulation method. Moreover, the pulling out process was carried out by steered molecular dynamics simulations. Considering π-π stacking and solvent accessibility together, base-CNT binding should be strongest on a graphene sheet and weakest on the inner CNT surface. When pulling the ssDNA out of the single-walled carbon nanotube (SWNT), the force exhibits characteristic fluctuations around a plateau about 300 pN. Each fluctuation force pulse to pull ssDNA corresponds to the exit of one base. In addition, the solvents used for the system are also of significant interest. Water does play an important role in encapsulation process but doesn't in the pulling out process. © 2012 The Royal Society of Chemistry.


Ababei R.,CNRS Paul Pascal Research Center | Ababei R.,CNRS Laboratory of Condensed Matter Chemistry, Bordeaux | Pichon C.,CNRS Paul Pascal Research Center | Pichon C.,National Polytechnic Institute of Toulouse | And 8 more authors.
Journal of the American Chemical Society | Year: 2013

The spin-crossover complex [Fe(LN5)(CN)2] ·H2O (1, LN5 = 2,13-dimethyl-3,6,9-12,18- pentaazabicyclo[12.3.1]octadeca-1(18),2,12,14,16-pentaene), reported previously by Nelson et al. in 1986, was reinvestigated, and its structure determined by single crystal X-ray diffraction for the first time. The reaction between [MnIII(saltmen)(H2O)]+ and this photomagnetic linker yielded the trinuclear molecular complex [{Mn(saltmen)} 2FeHS(LN5)(CN)2](ClO 4)2·0.5CH3OH (2) and the one-dimensional compound [{Mn(saltmen)}2FeLS(LN5)(CN) 2](ClO4)2·0.5C4H 10O·0.5H2O (3) depending on the addition order of the reagents (HS: High-Spin; LS: Low-Spin). Compound 3 exhibits a wave-shaped chain structure built from the assembly of the trinuclear [Mn III-NC-FeII] motif found in 2. Static magnetic measurements revealed the existence of antiferromagnetic Mn III···FeII (FeII HS, S = 2) interactions in the trinuclear entity of 2 via the cyanido bridge leading to an ST = 2 ground state. In the case of 3, concomitant ferromagnetic and antiferromagnetic exchange interactions are found along the chain due to the presence of two crystallographically independent {Mn2(saltmen) 2} units, which behave differently as shown by the magnetic susceptibility analysis, while the FeII (LS, S = 0) cyanido-bridging moiety is isolating these dinuclear MnIII units. ac susceptibility experiments indicated slow relaxation of the magnetization arising from the ferromagnetically coupled [Mn2] units (τ0 = 1.1 × 10-7 s and Δeff/kB = 13.9 K). Optical reflectivity and photomagnetic properties of 1 and 3 have been investigated in detail. These studies reveal that the photomagnetic properties of 1 are kept after its coordination to the acceptor MnIII/saltmen complexes, allowing in 3 to switch "on" and "off" the magnetic interaction between the photoinduced FeII HS unit (S = 2) and the Mn(III) ions. To the best of our knowledge, the compound 3 represents the first example of a coordination network of single-molecule magnets linked by spin-crossover units inducing thermally and photoreversible magnetic and optical properties. © 2013 American Chemical Society.


Huang W.,University of Illinois at Urbana - Champaign | Huang W.,Northeast Normal University | Cao X.,University of Illinois at Urbana - Champaign | Zhong S.,University of Illinois at Urbana - Champaign
Bioinformatics | Year: 2010

Motivation: In the pursuits of mechanistic understanding of cell differentiation, it is often necessary to compare multiple differentiation processes triggered by different external stimuli and internal perturbations. Available methods for comparing temporal gene expression patterns are limited to a gene-by-gene approach, which ignores co-expression information and thus is sensitive to measurement noise. Methods: We present a method for co-expression network based comparison of temporal expression patterns (NACEP). NACEP compares the temporal patterns of a gene between two experimental conditions, taking into consideration all of the possible co-expression modules that this gene may participate in. The NACEP program is available at http://biocomp.bioen.uiuc.edu/nacep.Results: We applied NACEP to analyze retinoid acid (RA)-induced differentiation of embryonic stem (ES) cells. The analysis suggests that RA may facilitate neural differentiation by inducing the shh and insulin receptor pathways. NACEP was also applied to compare the temporal responses of seven RNA inhibition (RNAi) experiments. As proof of concept, we demonstrate that the difference in the temporal responses to RNAi treatments can be used to derive interaction relationships of transcription factors (TFs), and therefore infer regulatory modules within a transcription network. In particular, the analysis suggested a novel regulatory relationship between two pluripotency regulators, Esrrb and Tbx3, which was supported by in vivo binding of Esrrb to the promoter of Tbx3. © The Author 2010. Published by Oxford University Press.


Li L.-S.,Northeast Normal University
Journal of Astrophysics and Astronomy | Year: 2014

The influence of the gravitational radiation damping on the evolution of the orbital elements of compact binary stars is examined by using the method of perturbation. The perturbation equations with the true anomaly as an independent variable are given. This effect results in both the secular and periodic variation of the semi-major axis, the eccentricity, the mean longitude at the epoch and the mean longitude. However, the longitude of periastron exhibits no secular variation, but only periodic variation. The effect of secular variation of the orbit would lead to collapse of the system of binary stars. The deduced formulae are applied to the calculation of secular variation of the orbital elements for three compact binary stars: PSR19 13 + 16, PSR J0737-3039 and M33X-7. The results obtained are discussed. © 2014 Indian Academy of Sciences.


Ma H.,CAS Changchun Institute of Optics and Fine Mechanics and Physics | Li B.,CAS Changchun Institute of Optics and Fine Mechanics and Physics | Zhang L.,CAS Changchun Institute of Optics and Fine Mechanics and Physics | Han D.,CAS Changchun Institute of Optics and Fine Mechanics and Physics | Zhu G.,Northeast Normal University
Journal of Materials Chemistry A | Year: 2015

A series of core-shell porous aromatic frameworks (PAFs) are synthesized for selective detection of nitro-explosives. The conjugated core-shell PAFs possess large surface areas, which can facilitate the pre-concentration of a targeted analyte, leading to superior sensitivity. The tunable LUMO energy levels of these core-shell PAFs make them selectively detect high explosive TNT and TNP from other competing nitro compounds. Moreover, vapor phase detection of nitro aromatics using PPC-PPyS-PAF-2 exhibits a two dimensional fluorescence signal response toward different nitro aromatics. The power to accurately recognize nitro aromatic explosives in the fluorescent 2D map highlights the core-shell PAFs as very promising materials for nitro explosive sensing. © The Royal Society of Chemistry 2015.


Xu C.,China Earthquake Administration | Xu X.,China Earthquake Administration | Yao Q.,China Earthquake Networks Center | Wang Y.,Northeast Normal University
Quarterly Journal of Engineering Geology and Hydrogeology | Year: 2013

The main purpose of this research is to evaluate the modelling capability and predictive power of a bivariate statistical method for earthquake-triggered landslide susceptibility mapping. A weight index (Wi) model was developed for the 2008 Wenchuan earthquake region in Sichuan Province, China, using a wide range of optical remote sensing data, and carried out on the basis of a geographic information system (GIS) platform. The 2008 Wenchuan earthquake triggered 196007 landslides, with a total area of 1150.43 km2, in an approximately oblong area around the Yingxiu-Beichuan coseismic surface fault-rupture (the Yingxiu-Beichuan fault). The landslides of the study area were mapped using visual interpretation of high-resolution satellite images and aerial photographs, both pre- and post-earth-quake, and checked in the field at various locations. As a consequence, a nearly complete inventory of landslides triggered by the Wenchuan earthquake was constructed. Topographic and geological data and earthquake-related information were collected, processed and constructed into a spatial database using GIS and image processing technologies. A total of 10 controlling parameters associated with the earthquake-triggered landslides were selected, including elevation, slope angle, slope aspect, slope curvature, slope position, lithology, seismic intensity, peak ground acceleration (PGA), distance from the Yingxiu-Beichuan fault, and distance along this fault. To assist with the development of the model, the complete dataset of 196007 landslides was randomly partitioned into two subsets; a training data-set, which contains 70% of the data (137204 landslides, with a total area of 809.96 km2), and a testing dataset accounting for 30% of the data (58803 landslides, with a total area of 340.47 km2). A landslide susceptibility index map was generated using the training dataset, the 10 impact factors, and the Wi model. In addition, for a conditionally dependent factor analysis, seven other factor-combination cases were also used to construct landslide susceptibility index maps. Finally, these eight landslide suscep-tibility maps were compared with the training data and testing data to obtain model capability (success rate) and predictive power (predictive rate) information. The validation results show that the success and predictive rates of the Wi modelling exceeded 90% for the approaches that include the use of seismic factors. The final landslide susceptibility map can be used to identify and delineate unstable suscepti-bility-prone areas, and help planners to choose favourable locations for development schemes, such as infrastructure, construction and environmental protection schemes. The generic component of this research would allow application in other regions affected by high-intensity earthquakes and unstable terrain covering very large areas. © 2013 The Geological Society of London.


Zheng M.,University of Tennessee at Knoxville | He C.,Northeast Normal University | He Q.,University of Tennessee at Knoxville
Ecotoxicology | Year: 2015

Free chlorine is a potent oxidizing agent and has been used extensively as a disinfectant in processes including water treatment. The presence of free chlorine residual is essential for the prevention of microbial regrowth in water distribution systems. However, excessive levels of free chlorine can cause adverse health effects. It is a major challenge to maintain appropriate levels of free chlorine residual in premise plumbing. As the first effort to assessing the fate of chlorine in premise plumbing using actual premise plumbing pipe sections, three piping materials frequently used in premise plumbing, i.e. copper, galvanized iron, and polyvinyl chloride (PVC), were investigated for their performance in maintaining free chlorine residual. Free chlorine decay was shown to follow first-order kinetics for all three pipe materials tested. The most rapid chlorine decay was observed in copper pipes, suggesting the need for higher chlorine dosage to maintain appropriate levels of free chlorine residual if copper piping is used. PVC pipes exhibited the least reactivity with free chlorine, indicative of the advantage of PVC as a premise plumbing material for maintaining free chlorine residual. The reactivity of copper piping with free chlorine was significantly hindered by the accumulation of pipe deposits. In contrast, the impact on chlorine decay by pipe deposits was not significant in galvanized iron and PVC pipes. Findings in this study are of great importance for the development of effective strategies for the control of free chlorine residual and prevention of microbiological contamination in premise plumbing. © 2015, Springer Science+Business Media New York.


Zhang F.,Northeast Normal University
Elektronika ir Elektrotechnika | Year: 2013

Based on the traditional DV-Hop algorithm and in order to overcome its existing drawbacks, an improved DV-Hop algorithm is brought forward in this paper by using the PSO algorithm. Through simulation experiments, it is found that both the average localization error and the localization coverage rate of PSO are better than that of DV-Hop. Moreover, with the increase of the number of nodes, the average localization error of PSO shows a downward trend and is less than that of DV-Hop.


Wang Y.,Northeast Normal University
Communications in Theoretical Physics | Year: 2010

In this paper, we define lower-dimensional volumes of spin manifolds with boundary. We compute the lower-dimensional volume Vol (2,2) for 5-dimensional and 6-dimensional spin manifolds with boundary and we also get the Kastler-Kalau-Walze type theorem in this case. © Chinese Physical Society and IOP Publishing Ltd.


Zhu P.,University of Alberta | Yang G.,University of Alberta | Yang G.,Northeast Normal University | Poopari M.R.,University of Alberta | And 2 more authors.
ChemPhysChem | Year: 2012

Vibrational circular dichroism (VCD) spectroscopy is utilized to reveal the detailed conformational distributions of the dominant serine species in aqueous solutions under three representative pH conditions of 1.0, 5.7, and 13.0, together with vibrational absorption (VA) spectroscopy, density functional theory (DFT), and molecular dynamics simulation. The experimental VA and VCD spectra of serine in H 2O and D 2O in the fingerprint region under three pH values are obtained. DFT calculations at the B3LYP/6-311++G(d,p) level are carried out for the protonated, zwitterionic, and deprotonated serine species. The lowest-energy conformers of all three species are identified and their corresponding VA and VCD spectra simulated. A comparison between the gas-phase simulations and the experimental VA and VCD spectra suggests that one or two of the most stable conformers of each species contribute predominantly to the observed data, although some discrepancies are noted. To account for the solvent effects, both the polarizable continuum model and the explicit solvation model are considered. Hydrogen-bonded protonated, zwitterionic, and deprotonated serine-(water) 6 clusters are constructed based on radial distribution function analyses and molecular dynamics snapshots. Geometry optimization and VA and VCD simulations are performed for these clusters at the B3LYP/6-311++G(d,p) level. Inclusion of the explicit water molecules is found to improve the agreement between theory and experiment noticeably in all three cases, thus enabling conclusive conformational distribution analyses of serine in aqueous solutions directly. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


Poopari M.R.,University of Alberta | Dezhahang Z.,University of Alberta | Yang G.,University of Alberta | Yang G.,Northeast Normal University | Xu Y.,University of Alberta
ChemPhysChem | Year: 2012

The conformational distributions of N-acetyl-L-cysteine (NALC) in aqueous solutions at several representative pH values are investigated using vibrational absorption (VA), UV/Vis, and vibrational circular dichroism (VCD) spectroscopy, together with DFT and molecular dynamics (MD) simulations. The experimental VA and UV/Vis spectra of NALC in water are obtained under strongly acid, neutral, and strongly basic conditions, as well as the VCD spectrum at pH 7 in D 2O. Extensive searches are carried out to locate the most stable conformers of the protonated, neutral, deprotonated, and doubly deprotonated NALC species at the B3LYP/6-311++G(d,p) level. The inclusion of the polarizable continuum model (PCM) modifies the geometries and the relative stabilities of the conformers noticeably. The simulated PCM VA spectra show significantly better agreement with the experimental data than the gas-phase ones, thus allowing assignment of the conformational distributions and dominant species under each experimental condition. To further properly account for the discrepancies noted between the experimental and simulated VCD spectra, PCM and the explicit solvent model are utilized. MD simulations are used to aid the modelling of the NALC-(water) N clusters. The geometry optimization, harmonic frequency calculations, and VA and VCD intensities are computed for the NALC-(water) 3,4 clusters at the B3LYP/6-311++G(d,p) level without and with the PCM. The inclusion of both explicit and implicit solvation models at the same time provides a decisively better agreement between theory and experiment and therefore conclusive information about the conformational distributions of NALC in water and hydrogen-bonding interactions between NALC and water molecules. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


Xia R.,Northeast Normal University
Advance Journal of Food Science and Technology | Year: 2015

Vitamins and minerals are necessary organic compounds for human body's normal activities, compared with ordinary people, athletes have the characteristics with the different demands on vitamins and minerals supplement. In this study, by analyzing the effects of vitamin in the movement function and minerals on the athletes sports ability, it discusses the nutrition supplement of vitamins as well as the reasonable measures to strengthen the athlete's minerals intake, which can provide scientific reference and improve the growth of the athlete, trying to formulate reasonable diet, so as to improve exercise capacity of athletes steadily. © Maxwell Scientific Organization, 2015.


Mei W.,CAS Changchun Institute of Applied Chemistry | Lu C.,Northeast Normal University | Yan J.,CAS Changchun Institute of Applied Chemistry | Wang Z.,CAS Changchun Institute of Applied Chemistry
RSC Advances | Year: 2014

Fluorene-containing anion exchange membranes were synthesized via the bromination reaction of poly(sulfone)s derived from 9,9-bis(3,5-dimethyl-4- hydroxyphenyl)fluorene (DMHPF), 4-fluorophenyl sulfone and 4,4′-biphenol, quaternization reaction using trimethylamine, and ion exchange; then the properties of these AEMs were fully characterized, and the structure-property relationship regarding this series of AEMs was elucidated. Brominated poly(fluorene ether sulfone)s (BrPFES) were characterized using proton nuclear magnetic resonance (1H NMR), and the bromination conversion, degree of functionalization (DF), and conversion of benzylmethyl groups were calculated. BrPFES was then quaternized by heterogeneous amination using trimethylamine, and then converted to quaternary ammonium bicarbonate by ion exchange. The properties of these AEMs were studied in terms of water uptakes, conductivities, swelling ratios, and mechanical properties. Compared to their homopolymer counterparts with similar ion exchange capacities (IEC), AEMs based on copolymers showed slightly lower conductivities but much lower water uptakes and swelling ratios, which can be explained by the fact that the continuation of hydrophilic domains in copolymers was interrupted by the incorporation of hydrophobic 4,4′-biphenol segments. © 2014 the Partner Organisations.


Gong J.,Georgia Institute of Technology | Li Y.,Georgia Institute of Technology | Li Y.,Northeast Normal University | Chai X.,Georgia Institute of Technology | And 2 more authors.
Journal of Physical Chemistry C | Year: 2010

The UV irradiation enhanced ZnO fiber sensors for organic gas detection at room temperature are reported in this paper. It has been well-known that the conductivity of ZnO fibers will increase when they are exposed to UV irradiation. However, it was found in this study that the trend of the conductivity increase under UV irradiation could be reversed if the organic gases adsorbed on the ZnO fiber surface. It was found that a linear relationship exists between the current response and the concentration of the organic gas. The results exhibited simple maneuverability for detecting parts per million concentration of organic gases at room temperature. The possible mechanism of photoconduction sensing for detecting an organic gas under UV light irradiation at room temperature is also discussed. © 2010 American Chemical Society.


Liu H.,Jilin University | Liu L.,Jilin University | Zhang H.,Northeast Normal University
Applied Soft Computing Journal | Year: 2011

Besides preprocessing, post-analysis also plays an important role in knowledge discovery. It can effectively assist users to grasp the obtained knowledge. However, many of data mining algorithms merely take performance into consideration and put the post-analysis of results aside. They generate a modest number of rules for the purpose of improving accuracy. Unfortunately, most induced rules are redundant or insignificant. Their presence not only confuses end-users in post-analysis, but also degrades efficiency in future decision task. Thus, it is necessary to eliminate redundant or irrelevant rules as more as possible. In this paper, we present an efficient post-processing method to prune redundant rules by virtue of the property of Galois connection, which inherently constrains rules with respect to objects. Its advantage is that information will not be lost greatly during pruning step. The experimental evaluation shows that the proposed method is competent for discarding a large number of superfluous rules effectively and a high compression factor will be achieved. What's more, the computational cost of our method is surprisingly lower than the Apriori method. © 2010 Elsevier B.V. All rights reserved.


Sun F.-J.,University of Illinois at Urbana - Champaign | Sun F.-J.,Northeast Normal University | Caetano-Anolles G.,University of Illinois at Urbana - Champaign
BMC Bioinformatics | Year: 2010

Background: Ribonuclease P is an ancient endonuclease that cleaves precursor tRNA and generally consists of a catalytic RNA subunit (RPR) and one or more proteins (RPPs). It represents an important macromolecular complex and model system that is universally distributed in life. Its putative origins have inspired fundamental hypotheses, including the proposal of an ancient RNA world.Results: To study the evolution of this complex, we constructed rooted phylogenetic trees of RPR molecules and substructures and estimated RPP age using a cladistic method that embeds structure directly into phylogenetic analysis. The general approach was used previously to study the evolution of tRNA, SINE RNA and 5S rRNA, the origins of metabolism, and the evolution and complexity of the protein world, and revealed here remarkable evolutionary patterns. Trees of molecules uncovered the tripartite nature of life and the early origin of archaeal RPRs. Trees of substructures showed molecules originated in stem P12 and were accessorized with a catalytic P1-P4 core structure before the first substructure was lost in Archaea. This core currently interacts with RPPs and ancient segments of the tRNA molecule. Finally, a census of protein domain structure in hundreds of genomes established RPPs appeared after the rise of metabolic enzymes at the onset of the protein world.Conclusions: The study provides a detailed account of the history and early diversification of a fundamental ribonucleoprotein and offers further evidence in support of the existence of a tripartite organismal world that originated by the segregation of archaeal lineages from an ancient community of primordial organisms. © 2010 Sun and Caetano-Anollés; licensee BioMed Central Ltd.


Ji G.,Peking University | He C.,Northeast Normal University | Tan Y.,Chinese Research Academy of Environmental Sciences
Ecological Engineering | Year: 2013

Real-time PCR was fist used to quantitatively study the spatial distribution of the absolute abundance, relative abundance, and relative richness of amoA, nxrA, narG, napA, nirK, qnorB, nosZ, nas, and nifH genes and anaerobic ammonium oxidation (anammox, or ANO) bacteria in four multimedia biofilters. The results showed that these multimedia biofilters could provide NH4 + and total nitrogen (TN) average removal efficiencies of 88%. Except for nifH, ANO and the other nitrogen removal functional genes all were dominantly enriched in different zones. In fact, ANO, napA, qnorB, nosZ, and nxrA were enriched by 5.6-330.1 times; and nirK, narG, amoA, and nas were enriched by 1.4-2.1 times. In addition, ANO, napA, qnorB, and nosZ showed partially or mutually beneficial cooperation. The nxrA and nirK genes showed protocooperation, and the amoA and narG genes showed partially beneficial cooperation. © 2013 Elsevier B.V.


Li L.-S.,Northeast Normal University
Astrophysics and Space Science | Year: 2010

The equation for the variation of the time of a periastron passage of binary stars has been solved by using the perturbation approach. The post-Newtonian effect on the variation of the time of a periastron passage has been examined within three gravitational theories. The results clearly show that the periastron passage of a binary star occurs earlier (advances) at each revolution. This effect has been calculated and discussed for ten binary stars. © Springer Science+Business Media B.V. 2010.


Fu Z.,Jilin University | Yang F.,Northeast Normal University
Information Processing Letters | Year: 2014

An essential problem in the design of holographic algorithms is to decide whether the required signatures can be realized under a suitable basis transformation (SRP). For holographic algorithms with matchgates on domain size 2, [1,2,4,5] have built a systematical theory. In this paper, we reduce SRP on domain size k≥3 to SRP on domain size 2 for holographic algorithms with matchgates on bases of rank 2. Furthermore, we generalize the collapse theorem of [3] to domain size k≥3. © 2014 Elsevier B.V.


Liu M.,Harbin Institute of Technology | Wang K.,Harbin Institute of Technology | Wang K.,Northeast Normal University
Journal of Theoretical Biology | Year: 2010

A new single-species model disturbed by both white noise and colored noise in a polluted environment is developed and analyzed. Sufficient criteria for extinction, stochastic nonpersistence in the mean, stochastic weak persistence in the mean, stochastic strong persistence in the mean and stochastic permanence of the species are established. The threshold between stochastic weak persistence in the mean and extinction is obtained. The results show that both white and colored environmental noises have sufficient effect to the survival results. © 2010 Elsevier Ltd.


Ubierna N.,Washington State University | Ubierna N.,Australian National University | Sun W.,Washington State University | Sun W.,Northeast Normal University | And 2 more authors.
Plant, Cell and Environment | Year: 2013

The efficiency of C4 photosynthesis in Zea mays, Miscanthus x giganteus and Flaveria bidentis in response to light was determined using measurements of gas exchange, 13CO2 photosynthetic discrimination, metabolite pools and spectroscopic assays, with models of C4 photosynthesis and leaf 13CO2 discrimination. Spectroscopic and metabolite assays suggested constant energy partitioning between the C4 and C3 cycles across photosynthetically active radiation (PAR). Leakiness (φ), modelled using C4 light-limited photosynthesis equations (φmod), matched values from the isotope method without simplifications (φis) and increased slightly from high to low PAR in all species. However, simplifications of bundle-sheath [CO2] and respiratory fractionation lead to large overestimations of φ at low PAR with the isotope method. These species used different strategies to maintain similar φ. For example, Z.mays had large rates of the C4 cycle and low bundle-sheath cells CO2conductance (gbs). While F.bidentis had larger gbs but lower respiration rates and M.giganteus had less C4 cycle capacity but low gbs, which resulted in similar φ. This demonstrates that low gbs is important for efficient C4 photosynthesis but it is not the only factor determining φ. Additionally, these C4 species are able to optimize photosynthesis and minimize φ over a range of PARs, including low light. © 2012 Blackwell Publishing Ltd.


Gong J.,Georgia Institute of Technology | Gong J.,Northeast Normal University | Zu X.,Georgia Institute of Technology | Li Y.,Georgia Institute of Technology | And 2 more authors.
Journal of Materials Chemistry | Year: 2011

We demonstrated the first example of Janus microspheres with ZnO nanowires. A method for electrochemical growth of ZnO nanowires on partially masked microspheres was adopted in the Janus particle synthesis. The coverage area of ZnO nanowires on the polystyrene or SiO2 microspheres can be tailored by varying the masking layer thickness. The pretreatment of microspheres with Zn2+ could effectively improve the growth of ZnO nanowires on the microspheres. The conductivity of the masking polymer is also an important factor for obtaining uniformly distributed ZnO nanowires on the microspheres. © The Royal Society of Chemistry.


Lv Y.,Changchun Normal University | Sun Z.,Northeast Normal University
European Journal of Soil Science | Year: 2016

This research examines the distribution of bi-conical reflectance of particulate surfaces with different particle sizes by multi-angular reflectance. Two types of particulate samples (called desert and cultivated soil) were sieved to a particle size range of 0.15-0.9 mm. The reflectance factors were measured at 570 or 330 different viewing positions for each illumination angle (45° and 60°). The reflectance was strongly non-Lambertian for all samples, but with markedly different patterns for the two types of particulate surface. Particle size was correlated with the bi-conical reflectance factor (BCRF) and anisotropic reflectance factor (ARF), respectively. The results showed a strong relation between BCRF and particle size in all viewing directions, except for the backward scattering direction, with an average R2 value of 0.9. The use of ARF improved the relation with particle size more in the backward scattering direction in the principal plane than with BCRF (R2 = 0.7 for BCRF; R2 = 0.91 for ARF). However, the strong relation between the ARF and particle size was limited in the forward and backward scattering directions, with an average R2 value of 0.86. The results showed the considerable potential of multi-angular reflectance for quantitative evaluation of the particle size of particulate surfaces. This approach appears to provide a promising empirical and theoretical basis for the future retrieval of soil particle size. Highlights:: The aim is to estimate the particle size from the reflectance of soil samples. Analysis of the relation between particle size and reflectance with multi-angular data. There was a strong relation between reflectance and particle size in 2π space. Multi-angular reflectance has the potential to evaluate quantitatively the particle size of soil. © 2016 British Society of Soil Science.


Wu J.-H.,Northeast Normal University | Artoni M.,European Laboratory for Nonlinear Spectroscopy LENS | Artoni M.,University of Brescia | La Rocca G.C.,Normal School of Pisa
Physical Review A - Atomic, Molecular, and Optical Physics | Year: 2015

Lossy atomic photonic crystals can be suitably tailored so that the real and imaginary parts of the susceptibility are, respectively, an odd and an even function of position. Such a parity-time (PT) space antisymmetry in the susceptibility requires neither optical gain nor negative refraction, but is rather attained by a combined control of the spatial modulation of both the atomic density and their dynamic level shift. These passive photonic crystals made of dressed atoms are characterized by a tunable unidirectional reflectionlessness accompanied by an appreciable degree of transmission. Interestingly, such peculiar properties are associated with non-Hermitian degeneracies of the crystal scattering matrix, which can then be directly observed through reflectivity measurements via a straightforward phase modulation of the atomic dynamic level shift and even off resonance. © 2015 American Physical Society.


Shi Z.C.,Dalian University of Technology | Zhao X.L.,Dalian University of Technology | Yi X.X.,Northeast Normal University
Physical Review A - Atomic, Molecular, and Optical Physics | Year: 2015

Based on the Lyapunov control, we present a scheme to realize state transfer with high fidelity by only modulating the boundary spins in a quantum spin-1/2 chain. Recall that the conventional transmission protocols aim at nonstationary state (or information) transfer from the first spin to the end spin at a fixed time. The present scheme possesses the following advantages. First, the scheme does not require precise manipulations of the control time. Second, it is robust against uncertainties in the initial states and fluctuations in the control fields. Third, the controls are exerted only on the boundary sites of the chain. It works for variable spin-1/2 chains with different periodic structures and has good scalability. The feasibility to replace the control fields by square pules is explored, which simplifies the realization in experiments. © 2015 American Physical Society.


Wu J.-H.,Northeast Normal University | Artoni M.,European Laboratory for Nonlinear Spectroscopy | Artoni M.,University of Brescia | La Rocca G.C.,Normal School of Pisa
Physical Review Letters | Year: 2014

Light propagation in optical lattices of driven cold atoms exhibits non-Hermitian degeneracies when the first-order modulation amplitudes of real and imaginary parts of the probe susceptibility are manipulated to be balanced. At these degeneracies, one may observe complete unidirectional reflectionless light propagation. This strictly occurs with no gain and can be easily tuned and fully reversed as supported by the transfer-matrix calculations and explained via a coupled-mode analysis. © 2014 American Physical Society.


Liu H.D.,CAS Beijing Institute of Applied Physics And Computational Mathematics | Liu H.D.,Northeast Normal University | Fu L.B.,CAS Beijing Institute of Applied Physics And Computational Mathematics | Fu L.B.,Beijing University of Technology
Physical Review Letters | Year: 2014

The Majorana's stellar representation, which represents the evolution of a quantum state with the trajectories of the Majorana stars on a Bloch sphere, provides an intuitive way to study a physical system with a high dimensional projective Hilbert space. In this Letter, we study the Berry phase by these stars and their loops on the Bloch sphere. It is shown that the Berry phase of a general spin state can be expressed by an elegant formula with the solid angles of Majorana star loops. Furthermore, these results can be used to a general state with arbitrary dimensions. To demonstrate our theory, we study a two mode interacting boson system. Finally, the relation between stars' correlations and quantum entanglement is discussed. © 2014 American Physical Society.


Xing S.,Nanyang Technological University | Xing S.,Northeast Normal University | Feng Y.,Nanyang Technological University | Tay Y.Y.,Nanyang Technological University | And 7 more authors.
Journal of the American Chemical Society | Year: 2010

We demonstrate a facile colloidal method for synthesizing Janus nanoparticles, whose eccentric polymer shells are exploited to fabricate eccentric bimetallic cores. © 2010 American Chemical Society.


Li M.,University of Chinese Academy of Sciences | Xu C.,University of Chinese Academy of Sciences | Wu L.,University of Chinese Academy of Sciences | Ren J.,University of Chinese Academy of Sciences | And 2 more authors.
Small | Year: 2013

Amyloid fibril formation is a critical step in Alzheimer's disease (AD) pathogenesis. Inhibition of Aβ aggregation has shown promising against AD and has been used in clinic trials. Here, a novel strategy is reported for the self-assembly of polyoxometalate-peptide (POM@P) hybrid particles as bifunctional Aβ inhibitors. The two-in-one bifunctional POM@P nanoparticles show an enhanced inhibition effect on amyloid aggregation in mice cerebrospinal fluid. Incorporating a clinically used Aβ fibril-staining dye, congo red (CR), into the hybrid colloidal spheres, the nanoparticles can also act as an effective fluorescent probe to monitor the inhibition process of POM@P via CR fluorescence change in real time. It is believed that such flexible organic-inorganic hybrid systems may prompt the design of new multifunctional materials for AD treatment. A Wells-Dawson-type phosphotungstate is combined with Aβ15-20, an Aβ-targted peptide inhibitor, to assemble spherical nanoparticles. The two-in-one bifunctional POM@P nanoparticles show an enhanced targeting inhibition effect on amyloid aggregation in mice cerebrospinal fluid. Incorporating an Aβ fibril-specific staining dye into the sphere, the nanoparticle can act as a fluorescent probe to monitor the inhibition process in real time. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


Zhou Y.H.,Dalian University of Technology | Shen H.Z.,Dalian University of Technology | Yi X.X.,Northeast Normal University
Physical Review A - Atomic, Molecular, and Optical Physics | Year: 2015

The photon blockade based on weak nonlinearities is called the unconventional photon blockade. The study of the unconventional photon blockade in recent decades has mainly focused on the χ(3) Kerr nonlinearity. In this paper, we study the photon blockade in two weakly coupled nonlinear cavities via χ(2) nonlinearity, where χ(2) mediates the conversion of a single photon in the cavity with high frequency into two photons with low frequency in another cavity. When the two cavity modes are driven simultaneously, our calculations show that the strong photon antibunching can be obtained in the cavity. The optimal condition for strong antibunching is found by analytic calculations and numerical simulations, and discussions of the optimal condition are presented. The differences between the present scheme and that with χ(3) nonlinearity are discussed. This scheme is not sensitive to the change of decay rates, which makes the experimental realization easy. © 2015 American Physical Society.


Guan J.,CAS Changchun Institute of Applied Chemistry | Guan J.,University of Chinese Academy of Sciences | Wu G.-J.,Northeast Normal University | Han F.-S.,CAS Changchun Institute of Applied Chemistry | Han F.-S.,Dalian University of Technology
Chemistry - A European Journal | Year: 2014

A novel protocol for the Pd-catalyzed ortho-arylation of aryl phosphinamide with boronic acid is reported. By using phosphinamide as a new directing group, the reaction proceeds efficiently under mild conditions at 40 °C. Mechanistic studies reveal that the reaction proceeds via a PdII to Pd0 cycle. The phosphinamide group is also shown to be an effective orienting group for direct C-H amination. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


Hamid A.S.,Jilin University | Tesfamariam S.G.,Northeast Normal University | Zhang Y.,Jilin University | Zhang Z.G.,Jilin University
Oncology Letters | Year: 2013

Hepatocellular carcinoma (HCC) is the most well-known primary liver malignancy worldwide. Its incidence is rising at alarming rates and has become a public concern globally. It is more frequent in developing countries than in industrialized countries with respect to geographical variation, ethnic disparities and socioeconomic status. Dietary exposure to aflatoxins is among the major HCC risk factors. Aflatoxin B1, which is a genotoxic hepatocarcinogen, which presumptively causes cancer by inducing DNA adducts leading to genetic changes in target liver cells. AFB1 is metabolized by cytochrome-P450 enzymes to the reactive intermediate AFB1-8, 9 epoxide (AFBO) which binds to liver cell DNA, resulting in DNA adducts. DNA adducts interact with the guanine bases of liver cell DNA and cause a mutational effect in the P53 tumor suppressor gene at the codon 249 hotspot in exon 7, which may lead to HCC. Approximately 4.5 billion of the world's population is exposed to aflatoxin-contaminated food, particularly in low-income countries. Prevention involves treating crops that are susceptible to fungal contamination, appropriate handling of foodstuffs and the use of chemopreventive intervention. Moreover, an integrated network collaboration of different sectors, including public health, agricultural departments and mass media, is required to ensure effective food regulation systems so as to minimize the contamination of food by aflatoxins.


Liu M.,Harbin Institute of Technology | Wang K.,Harbin Institute of Technology | Wang K.,Northeast Normal University
Mathematical and Computer Modelling | Year: 2011

Taking both white noise and colored environmental noise into account, a general stochastic logistic model under regime switching is proposed and studied. Sufficient conditions for extinction, nonpersistence in the mean, weak persistence, stochastic permanence and global attractivity are established. The critical number between weak persistence and extinction is obtained. Moreover, some simulation figures are introduced to illustrate the main results. © 2011 Elsevier Ltd.


Hu G.,Harbin Institute of Technology | Wang K.,Harbin Institute of Technology | Wang K.,Northeast Normal University
Computers and Mathematics with Applications | Year: 2011

This paper focuses on the method of the simulation of a stochastic system and the main method of our paper is the Monte Carlo computation simulation method. Taking the stochastic Logistic equation as an example, we present the simulation of the sample trajectory by Euler scheme and the invariant probability distribution of stochastic differential equations with the Monte Carlo method. We also compare the simulation result with the analytical result for the autonomous stochastic Logistic model. Moreover, the stochastic Logistic equation with Markovian switching which is described by a Markov chain taking values in a finite state space is considered. © 2011 Elsevier Ltd. All rights reserved.


Nanao M.H.,Pierre Mendes-France University | Vinos-Poyo T.,French National Institute for Agricultural Research | Brunoud G.,CNRS Laboratory of Plant Reproduction and Development | Thevenon E.,French National Institute for Agricultural Research | And 10 more authors.
Nature communications | Year: 2014

The plant hormone auxin is a key morphogenetic regulator acting from embryogenesis onwards. Transcriptional events in response to auxin are mediated by the auxin response factor (ARF) transcription factors and the Aux/IAA (IAA) transcriptional repressors. At low auxin concentrations, IAA repressors associate with ARF proteins and recruit corepressors that prevent auxin-induced gene expression. At higher auxin concentrations, IAAs are degraded and ARFs become free to regulate auxin-responsive genes. The interaction between ARFs and IAAs is thus central to auxin signalling and occurs through the highly conserved domain III/IV present in both types of proteins. Here, we report the crystal structure of ARF5 domain III/IV and reveal the molecular determinants of ARF-IAA interactions. We further provide evidence that ARFs have the potential to oligomerize, a property that could be important for gene regulation in response to auxin.


Liu G.,Northeast Normal University | Liu G.,Shenzhen University | Xu H.,Shenzhen University | Zhang L.,Shenzhen University | Zheng Y.,Shenzhen University
Plant and Cell Physiology | Year: 2011

Late embryogenesis abundant (LEA) group 4 (LEA4) proteins play an important role in the water stress tolerance of plants. Although they have been hypothesized to stabilize macromolecules in stressed cells, the protective functions and mechanisms of LEA4 proteins are still not clear. In this study, the metal binding properties of two related soybean LEA4 proteins, GmPM1 and GmPM9, were tested using immobilized metal ion affinity chromatography (IMAC). The metal ions Fe3+, Ni2+, Cu2+ and Zn 2+ were observed to bind these two proteins, while Ca2+, Mg2+ or Mn2+ did not. Results from isothermal titration calorimetry (ITC) indicated that the binding affinity of GmPM1 for Fe 3+ was stronger than that of GmPM9. Hydroxyl radicals generated by the Fe3+/H2O2 system were scavenged by both GmPM1 and GmPM9 in the absence or the presence of high ionic conditions (100 mM NaCl), although the scavenging activity of GmPM1 was significantly greater than that of GmPM9. These results suggest that GmPM1 and GmPM9 are metal-binding proteins which may function in reducing oxidative damage induced by abiotic stress in plants. © 2011 The Author.


Wang Y.,CAS Changchun Institute of Optics and Fine Mechanics and Physics | Wang Y.,University of Chinese Academy of Sciences | Li B.,CAS Changchun Institute of Optics and Fine Mechanics and Physics | Li B.,Northeast Normal University | And 2 more authors.
Langmuir | Year: 2013

In this paper, the fabrication, characterization, and application in oxygen sensing are reported for a novel multifunctional nanomaterial of [Ru(bpy) 2phen-MMS] (bpy, 2,2′-bipyridyl; phen, phenathrolin) which was simply prepared by covalently grafting the ruthenium(II) polypyridyl compounds into the channels of magnetic mesoporous silica nanocomposites (MMS). Scanning electron microscopy, transmission electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction, N2 adsorption-desorption, a superconducting quantum interference device, UV-vis spectroscopy, and photoluminescence spectra were used to characterize the samples. The well-designed multifunctional nanocomposites show superparamagnetic behavior and ordered mesoporous characteristics and exhibit a strong red-orange metal-to-ligand charge transfer emission. In addition, the obtained nanocomposites give high performance in oxygen sensing with high sensitivity (I0/I100 = 5.2), good Stern-Volmer characteristics (R 2 = 0.9995), and short response/recovery times (t↓ = 6 s and t↑ = 12 s). The magnetic, mesoporous, luminescent, and oxygen-sensing properties of this multifunctional nanostructure make it hold great promise as a novel multifunctional oxygen-sensing system for chemical/biosensor. © 2013 American Chemical Society.


Wang Y.,Chinese Academy of Sciences | Wang Y.,CAS Lanzhou Cold and Arid Regions Environmental and Engineering Research Institute | Wang S.,Chinese Academy of Sciences | Wang S.,Northeast Normal University | And 5 more authors.
Journal of Chromatography A | Year: 2013

Core/shell structured magnetic Fe3O4/polydopamine (Fe3O4/PDA) nanoparticles have been successfully synthesized and developed as a magnetic solid-phase extraction (SPE) adsorbent in dispersion mode for the determination of trace polycyclic aromatic hydrocarbons (PAHs) in environmental samples. The Fe3O4/PDA synthetic procedure is simple and involves no organic solvents. Only 20mg of Fe3O4/PDA adsorbents are required to extract PAHs from 500mL water samples. The adsorption attains equilibrium rapidly and analysts are eluted with acetonitrile readily. The extraction efficiency is not influenced by salt concentrations up to 300mM and pH values over the range 4-11. Under optimized conditions, the detection limits of PAHs are in the range of 0.5-1.9ngL-1. The accuracy of the method is evaluated by the recoveries of PAHs from environmental samples. Good recoveries (76.4-107%) with low relative standard deviations from 1.0% to 9.7% are achieved. Comparison study shows that the recoveries of target PAHs are low when they are extracted using traditional SPE method even with the addition of methanol or tetrabutylammonium bromide surfactants in water samples, suggesting great application potential of magnetic SPE method to preconcentrate highly hydrophobic contaminants (such as PAHs) from large volume of water samples. This new SPE method provides several advantages, such as simplicity, low environmental impact, high extraction efficiency, high breakthrough volumes, convenient extraction procedure, and short analysis time. © 2013 Elsevier B.V.


Geng J.,University of Chinese Academy of Sciences | Li M.,University of Chinese Academy of Sciences | Ren J.,University of Chinese Academy of Sciences | Wang E.,Northeast Normal University | Qu X.,University of Chinese Academy of Sciences
Angewandte Chemie - International Edition | Year: 2011

Inorganic amyloid inhibitors: Four types of polyoxometalates (POMs) were found to be efficient inhibitors of amyloid formation by amyloid β peptides (Aβ; see picture: unlike the top POM (red), the bottom POM (dark green) inhibited amyloid formation). The inhibition selectivity of POMs is due to size-specific electrostatic interactions between POMs and Aβ through binding to the positively charged His13-Lys16 cluster region of Aβ. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


Guan W.,Kyoto University | Guan W.,Northeast Normal University | Sakaki S.,Kyoto University | Kurahashi T.,Kyoto University | Matsubara S.,Kyoto University
ACS Catalysis | Year: 2015

Two nonstrained C-C σ-bonds are cleaved in a novel nickel(0)/LA-catalyzed decyanative [4 + 2] cycloaddition of o-arylcarboxybenzonitrile with alkyne, where LA represents a Lewis acid such as methylaluminum bis(2,6-di-tert-butyl-4-methylphenoxide). The catalytic cycle of this reaction is systematically investigated here by DFT method to clarify the reasons two nonstrained C-C σ-bonds are successfully cleaved in this reaction. DFT calculations indicate that this reaction occurs via the oxidative addition of the C-CN σ-bond of o-arylcarboxybenzonitrile to the Ni(0) center, alkyne insertion into the Ni(II)-aryl bond, C-C coupling between the vinyl carbon and the carboxyl carbon atoms, and β-aryl elimination followed by reductive elimination. One LA interacts with the cyano nitrogen atom of o-arylcarboxybenzonitrile to accelerate the oxidative addition by stabilizing the unoccupied σ∗ + π∗ C-CN antibonding orbital. One more LA interacts with the carbonyl oxygen of o-arylcarboxybenzonitrile. This LA enhances the electrophilic nature of the carbonyl carbon to accelerate the C-C coupling, because this step occurs through the nucleophilic attack of the vinyl carbon at the carbonyl carbon atom. The second C-C σ-bond activation occurs via β-aryl elimination, the transition state of which is stabilized by the interaction between LA and the carbonyl oxygen atom. These results lead to the clear conclusion that the presence of two LA molecules is crucial to achieve the dual C-C σ-bond cleavages. The reasons LA accelerates the oxidative addition of the C-CN σ-bond to the nickel(0) center and the C-C coupling followed by the β-aryl elimination are discussed in detail. (Chemical Equation Presented). © 2014 American Chemical Society.


Peelen M.V.,University of Trento | Bracci S.,University of Trento | Lu X.,Northeast Normal University | He C.,Beijing Normal University | And 3 more authors.
Journal of Cognitive Neuroscience | Year: 2013

Previous studies have provided evidence for a tool-selective region in left lateral occipitotemporal cortex (LOTC). This region responds selectively to pictures of tools and to characteristic visual tool motion. The present human fMRI study tested whether visual experience is required for the development of tool-selective responses in left LOTC. Words referring to tools, animals, and nonmanipulable objects were presented auditorily to 14 congenitally blind and 16 sighted participants. Sighted participants additionally viewed pictures of these objects. In whole-brain group analyses, sighted participants showed toolselective activity in left LOTC in both visual and auditory tasks. Importantly, virtually identical tool-selective LOTC activity was found in the congenitally blind group performing the auditory task. Furthermore, both groups showed equally strong toolselective activity for auditory stimuli in a tool-selective LOTC region defined by the picture-viewing task in the sighted group. Detailed analyses in individual participants showed significant tool-selective LOTC activity in 13 of 14 blind participants and 14 of 16 sighted participants. The strength and anatomical location of this activity were indistinguishable across groups. Finally, both blind and sighted groups showed significant resting state functional connectivity between left LOTC and a bilateral frontoparietal network. Together, these results indicate that toolselective activity in left LOTC develops without ever having seen a tool or its motion. This finding puts constraints on the possible role that this region could have in tool processing and, more generally, provides new insights into the principles shaping the functional organization of OTC. © 2013 Massachusetts Institute of Technology.


Guo Z.,Hebei University of Engineering | Mu J.,Hebei University of Engineering | Chen B.,Northeast Normal University
Ceramics International | Year: 2015

The three-dimensional flower-like TNFePc hierarchical microstructures were fabricated by a simple solvothermal method. The as-obtained products exhibited high adsorption capacity and excellent simultaneously visible-light-driven photocatalytic performance for Rhodamine B (RB) under visible-light. Repetitive tests showed that the flower-like TNFePc hierarchical microstructures could maintain high catalytic activity over several cycles, and it had a better regeneration capability under mild conditions. Finally, a possible mechanism for the formation of three-dimensional flower-like TNFePc was suggested based on the evolution of morphology as a function of solvothermal time, which involved the initial formation of microparticles followed by their recrystallize to microspheres and transformation into three-dimensional flower-like hierarchical microstructures by mass diffusion and Ostwald ripening.


Wang G.-G.,Jiangsu University | Guo L.,CAS Changchun Institute of Optics and Fine Mechanics and Physics | Duan H.,Northeast Normal University | Wang H.,CAS Changchun Institute of Optics and Fine Mechanics and Physics
Journal of Computational and Theoretical Nanoscience | Year: 2014

A novel robust meta-heuristic optimization algorithm, which can be considered as an improvement of the recently developed firefly algorithm, is proposed to solve global numerical optimization problems. The improvement includes the addition of information exchange between the top fireflies, or the optimal solutions during the process of the light intensity updating. The detailed implementation procedure for this improved meta-heuristic method is also described. Standard benchmarking functions are applied to verify the effects of these improvements and it is illustrated that, in most situations, the performance of this improved firefly algorithm (IFA) is superior to or at least highly competitive with the standard firefly algorithm, a differential evolution method, a particle swarm optimizer, and a biogeography-based optimizer. Especially, this new method can accelerate the global convergence speed to the true global optimum while preserving the main feature of the basic FA. © 2014 American Scientific Publishers.


Ai X.,Jilin University | Niu L.,Jilin University | Li Y.,Northeast Normal University | Yang F.,Jilin University | Su X.,Jilin University
Talanta | Year: 2012

In this paper, a novel optical biosensor for amantadine (AD) determination has been constructed successfully based on the fluorescence resonance energy transfer (FRET) between water-soluble β-Cyclodextrin (β-CD)- functionalized CdTe quantum dots (QDs) and Rhodamine B (RB). RB could enter the cavity of β-CD by hydrophobic interaction, and the process of FRET between QDs and RB occurred. However, the process of FRET was switched off with the addition of AD, due to its larger hydrophobic association constant with β-CD than that of RB. The fluorescence intensity of CdTe QDs (donor) would increase gradually with the increasing concentration of AD, which shown a good linear relationship in the range of 1×10-5-1.6×10 -4 mol/L with a correlation coefficient R2=0.998. We also obtained a satisfactory result using this spectrophotometric method for the determination of AD in pharmaceutical formulation. Furthermore, β-CD-functionalized CdTe QDs with AD in the cavity were incubated with target HepG2 cells and could be observed in the cytoplasm of cells. The β-CD-functionalized CdTe QDs could act as a visible biomarker for AD in cancer cells fluorescence imaging, which presents a potential application in biomedical field. © 2012 Elsevier B.V.


Gao J.,Northeast Normal University | Wakarchuk W.,Ryerson University
Journal of Bacteriology | Year: 2014

The Gram-positive bacterium Cellulomonas fimi produces a large array of carbohydrate-active enzymes. Analysis of the collection of carbohydrate-active enzymes from the recent genome sequence of C. fimi ATCC 484 shows a large number of uncharacterized genes for glycoside hydrolase (GH) enzymes potentially involved in biomass utilization. To investigate the enzymatic activity of potential β-glucosidases in C. fimi, genes encoding several GH3 enzymes and one GH1 enzyme were cloned and recombinant proteins were expressed in Escherichia coli. Biochemical analysis of these proteins revealed that the enzymes exhibited different substrate specificities for para-nitrophenol-linked substrates (pNP), disaccharides, and oligosaccharides. Celf_2726 encoded a bifunctional enzyme with β-D-xylopyranosidase and α-L-arabinofuranosidase activities, based on pNPlinked substrates (CfXyl3A). Celf_0140 encoded a β-D-glucosidase with activity on β-1,3-and β-1,6-linked glucosyl disaccharides as well as pNP-β-Glc (CfBgl3A). Celf_0468 encoded a β-D-glucosidase with hydrolysis of pNP-β-Glc and hydrolysis/transglycosylation activities only on β-1,6-linked glucosyl disaccharide (CfBgl3B). Celf_3372 encoded a GH3 family member with broad aryl-β-D-glycosidase substrate specificity. Celf_2783 encoded the GH1 family member (CfBgl1), which was found to hydrolyze pNP-β-Glc/Fuc/Gal, as well as cellotetraose and cellopentaose. CfBgl1 also had good activity on β-1,2-and β-1,3-linked disaccharides but had only very weak activity on β-1,4/6-linked glucose. © 2014, American Society for Microbiology.


Huang J.,CAS Changchun Institute of Applied Chemistry | Zhu Y.,CAS Changchun Institute of Applied Chemistry | Jiang W.,CAS Changchun Institute of Applied Chemistry | Tang Q.,Northeast Normal University
Composites Part A: Applied Science and Manufacturing | Year: 2015

It is known that shear-flow can induce units to assemble into vorticity-aligned stripe-structures in confined geometries. This study shows that the microstructure and the property of the stripe in polymer thin film can be well tuned by adjusting the viscosity ratio between dispersed phase and continuous phase. Polypropylene (PP)/poly(styrene-ethylene/butadiene-styrene) (SEBS)/octadecylamine functionalized multiwalled carbon nanotubes (ODA-MWCNTs) composites with different viscosity ratios were prepared by either pre-compounding ODA-MWCNT into PP or SEBS in a microcompounder. Under the induction of shear-flow, ODA-MWCNT and SEBS spontaneously assembled into vorticity-aligned stripes in PP thin films for all the composites with different viscosity ratios, resulting in the property of conductive anisotropy for the film. Interestingly, it was found that both the microstructures and the electrical properties of MWCNT stripes in PP thin films prepared from the composites with different viscosity ratios were significantly different. © 2014 Elsevier Ltd.


Liu X.W.,Northeast Normal University
Applied Mechanics and Materials | Year: 2014

This paper evaluates the environmental art design based on digital technology by analyzing its digitalization and level as well as the design process. The analysis on the straight line and free curve composition rules of digital environmental art and the verification of its feasibility provide new design strategy for environmental art design. © (2014) Trans Tech Publications, Switzerland.


Zhang X.Y.,Dalian University of Technology | Huang X.L.,Liaoning Normal University | Yi X.X.,Northeast Normal University
Journal of Physics A: Mathematical and Theoretical | Year: 2014

The effects of a non-Markovian reservoir on the performance of an ideal quantum Otto heat engine are investigated. By coupling the cavity to a hot non-Markovian reservoir, the cavity can be enabled to reach a steady state corresponding to an effective temperature higher than the temperature of the hot reservoir. This observation shows that the quantum Otto heat engine can transport heat from a cold reservoir to a hot reservoir with positive net work output under certain conditions. Also, when the temperature of the hot reservoir lies in certain regions, the efficiency of the quantum Otto heat engine can exceed the efficiency of classical Carnot heat engine. © 2014 IOP Publishing Ltd.


Ge M.-L.,Nankai University | Xue K.,Northeast Normal University
International Journal of Modern Physics B | Year: 2012

The connection between YangBaxter system and quantum information has been discussed. Based on the topological basis for both TemperleyLieb (TL) algebra and BirmanWenzl (BW) algebra the representations of N by N braiding matrices associated with the corresponding N 2 by N 2 ones are obtained. Some of physical consequences of the braiding matrices connecting with quantum information are shown. © World Scientific Publishing Company.


Lu D.-Y.,Jilin Institute of Chemical Technology | Zhang L.,Jilin Institute of Chemical Technology | Zhang L.,Northeast Normal University | Sun X.-Y.,Jilin Institute of Chemical Technology
Ceramics International | Year: 2013

The influence of the sintering temperature (Ts) on the structure, dielectric and valence-state properties of (Ba1-xEu x)TiO3 (x=0.05) ceramics was investigated using X-ray diffraction (XRD), scanning electron microscopy (SEM), electron paramagnetic resonance (EPR), Raman spectroscopy, and dielectric temperature measurements. An increase in Ts can increase the solubility limit of Eu in BaTiO 3. When the Ts was increased to 1450 °C, a high-k 'Y5V' (ε′RT=8500) ceramic (C-BE5T) with a single-phase cubic structure was obtained. The dielectric peak shifted rapidly toward lower temperatures with increasing Ts at a rate of -0.46 °C/K. A symmetric (200) XRD peak, exaggerated grain growth (5.6 μm), a mixed valence of Eu2+/Eu3+, an asymmetric main Raman band at 2494 cm-1 and a weak sharp band at 1516 cm-1 in the high-wavenumber region are characteristics of cubic symmetry of C-BE5T. The formation of a solid solution of C-BE5T and defect chemistry are discussed. © 2013 Elsevier Ltd and Techna Group S.r.l.


Fang H.,CAS Beijing Institute of Geographic Sciences and Nature Resources Research | Wei S.,CAS Beijing Institute of Geographic Sciences and Nature Resources Research | Wei S.,Northeast Normal University | Jiang C.,CAS Beijing Institute of Geographic Sciences and Nature Resources Research | Scipal K.,European Space Agency
Remote Sensing of Environment | Year: 2012

Uncertainty information for global leaf area index (LAI) products is important for global modeling studies but usually difficult to systematically obtain at a global scale. Here, we present a new method that cross-validates existing global LAI products and produces consistent uncertainty information. The method is based on a triple collocation error model (TCEM) that assumes errors among LAI products are not correlated. Global monthly absolute and relative uncertainties, in 0.05° spatial resolutions, were generated for MODIS, CYCLOPES, and GLOBCARBON LAI products, with reasonable agreement in terms of spatial patterns and biome types. CYCLOPES shows the lowest absolute and relative uncertainties, followed by GLOBCARBON and MODIS. Grasses, crops, shrubs, and savannas usually have lower uncertainties than forests in association with the relatively larger forest LAI. With their densely vegetated canopies, tropical regions exhibit the highest absolute uncertainties but the lowest relative uncertainties, the latter of which tend to increase with higher latitudes. The estimated uncertainties of CYCLOPES generally meet the quality requirements (±. 0.5) proposed by the Global Climate Observing System (GCOS), whereas for MODIS and GLOBCARBON only non-forest biome types have met the requirement. Nevertheless, none of the products seems to be within a relative uncertainty requirements of 20%. Further independent validation and comparative studies are expected to provide a fair assessment of uncertainties derived from TCEM. Overall, the proposed TCEM is straightforward and could be automated for the systematic processing of real time remote sensing observations to provide theoretical uncertainty information for a wider range of land products. © 2012 Elsevier Inc.


Fang H.,CAS Beijing Institute of Geographic Sciences and Nature Resources Research | Wei S.,CAS Beijing Institute of Geographic Sciences and Nature Resources Research | Wei S.,Northeast Normal University | Liang S.,University of Maryland University College | Liang S.,Beijing Normal University
Remote Sensing of Environment | Year: 2012

The objective of this paper is to quantitatively validate the global MODIS and CYCLOPES leaf area index (LAI) products using a global LAI field measurement database created on the basis of a literature review and major validation campaigns. The MODIS LAI product suite, containing the Terra Collection 4 (C4), Terra Collection 5 (C5) and Terra. +. Aqua combined C5, was analyzed, with considerable attention paid to the quality control (QC) information. The CYCLOPES V3.1 LAI product was similarly analyzed with regard to the status map (SM) layer. In general, the MODIS LAI has improved consistently over all releases. MODIS C5 data retrieved with the main algorithm (QC < 64) and CYCLOPES data showed a similar range of uncertainties (1.0-1.2). Uncertainties for the best MODIS C5 (QC = 0) and CYCLOPES (SM = 0) estimates were around 0.9-1.1. The overall mean differences between the best MODIS C5 and CYCLOPES were within ± 0.10. The highest correspondence was obtained for woody biomes from the best MCD15 C5 data (RMSE = 0.80). Results indicate that the uncertainties in current LAI products (around ± 1.0) are still unable to meet the accuracy requirement of GCOS (± 0.5). Although there are limitations, we recommend MODIS C5 retrieved with the main algorithm (QC < 64) and CYCLOPES for the user community. This study demonstrates the necessity of exploring uncertainties related to the true and effective LAIs separately, and reveals the importance of referring to the quality assessment information. More field measurements are required for further studies, which should focus on under-sampled biome types and areas. © 2011 Elsevier Inc.


Gao P.,Northeast Normal University | Gao P.,Jilin University
ESAIM - Control, Optimisation and Calculus of Variations | Year: 2016

In this paper, we establish the Lebeau-Robbiano inequality for the one-dimensional fourth order elliptic operator by using a point-wise estimate. Based on this inequality, we obtain the null controllability of one-dimensional stochastic fractional order Cahn-Hilliard equation. © EDP Sciences, SMAI 2016.


Lu D.-Y.,Jilin Institute of Chemical Technology | Han D.-D.,Jilin Institute of Chemical Technology | Han D.-D.,Northeast Normal University
Ceramics International | Year: 2013

Nominal (Ba1-xCex)(Ti0.95-x/4Ce 0.05)O3 ceramics were prepared by a solid state reaction method. A complete solid solution called BC3TC5 was formed only at x=0.03, with a single-phase perovskite structure. The structural and dielectric properties of BC3TC5 were investigated by X-ray diffraction, scanning electron microscopy, Raman spectroscopy, electron paramagnetic resonance, and dielectric measurements. BC3TC5 exhibited a cubic structure and a non-uniform microstructure. Ti-vacancy defects exist in BC3TC5, which has a feature of mixed valence of Ba-site Ce3+ and Ti-site Ce4+. The amphoteric Ce3+/Ce4+ ions can induce an in-situ diffuse phase transition at the Curie point of BaTiO3 (TC=125 C). BC3TC5 exhibits a high-k behavior (ε′m=9470) and low dielectric loss (tan δ<0.025). © 2013 Elsevier Ltd and Techna Group S.r.l.


Wang J.,Tianjin University of Technology and Education | Wang Y.,Northeast Normal University
International Journal of Geometric Methods in Modern Physics | Year: 2015

The Kastler-Kalau-Walze theorem, announced by A. Connes, shows that the Wodzicki residue of the inverse square of the Dirac operator is proportional to the Einstein-Hilbert action of general relativity. In this paper, we prove a Kastler-Kalau-Walze type theorem for five-dimensional manifolds with boundary. © 2015 World Scientific Publishing Company.


Wang Y.,Northeast Normal University
International Journal of Geometric Methods in Modern Physics | Year: 2015

In this paper, using the Greiner's approach to heat kernel asymptotics, we give new proofs of the equivariant Gauss-Bonnet-Chern formula and the variation formulas for the equivariant Ray-Singer metric, which are originally due to Bismut and Zhang. © 2015 World Scientific Publishing Company.


Zhang H.,CAS Changchun Northeast Institute of Geography and Agroecology | Irving L.J.,University of Tsukuba | Tian Y.,Northeast Normal University | Zhou D.,CAS Changchun Northeast Institute of Geography and Agroecology
South African Journal of Botany | Year: 2012

Effects of salinity, temperature and their interactions on final percentage and the rate of germination were evaluated for two grasses, the halophytic Chloris virgata and the glycophyte, Digitaria sanguinalis. Seeds were germinated in 0, 50, 100, 150, 200 and 250. mM NaCl solutions under constant temperatures of 15, 20, 25, 30°C and alternating temperatures of 15/25 and 20/30°C with a 12. h photoperiod. In D. sanguinalis, the hydrotime model described the time course of seed germination well; however, it provided a poor description of C. virgata germination. In both species, most of the un-germinated seeds transferred to distilled water were still viable. Results suggest that seeds take salt up, causing inhibition of germination at sub-toxic concentrations; however, when returned to pure water, this extra salt may be able to increase germination rates and percentages. © 2011 South African Association of Botanists.


Ou X.,Northeast Normal University
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada | Year: 2010

An array of studies have reported that the spaceflight environment is mutagenic and may induce phenotypic and genetic changes in diverse organisms. We reported recently that in at least some plant species (e.g., rice) the spaceflight environment can be particularly potent in generating heritable epigenetic changes in the form of altered cytosine methylation patterns and activation of transposable elements. To further study the issue of spaceflight-induced genomic instability, and in particular to test whether the incurred genetic and epigenetic changes are connected or independent of each other, we performed the present study. We subjected seeds of the standard laboratory rice (Oryza sativa L.) cultivar Nipponbare to a spaceflight in the spaceship Long March 2 for 18 days. We then investigated the genetic and DNA methylation stabilities of 11 randomly selected plants germinated from the spaceflown seeds by using two kinds of DNA markers, amplified fragment length polymorphism (AFLP) and methylation sensitive amplified polymorphism (MSAP). For AFLP, by using 15 primer combinations, we assessed 460 genomic loci and found that the frequencies of genetic changes across the 11 plants ranged from 0.7% to 6.7% with an average frequency of 3.5%. For MSAP, by using 14 primer combinations, we assessed 467 loci and detected the occurrence of four major types of cytosine methylation alterations at the CCGG sites, namely CG or CNG hypomethylation and CG or CNG hypermethylation. Collectively, the frequencies of the two kinds of hypermethylation, CG (1.95%) and CNG (1.44%), are about two times higher than those of the two kinds of hypomethylation, CG (0.76%) and CNG (0.80%), though different plants showed variable frequencies for each type of alteration. Further analysis suggested that both the genetic and cytosine methylation changes manifested apparent mutational bias towards specific genomic regions, but the two kinds of instabilities are independent of each other based on correlation analysis.


The variation of the instantaneous rotational angular velocity of the rigid Earth in the lunar-solar gravitational field is studied. The formula is derived for variation of the instantaneous angular velocity of the rigid oblate Earth using the potential function from Euler’s dynamic equations. The theoretical results show that under the influence of the gravitational field of the Moon and the Sun the Earth instantaneous angular velocity varies with periodic terms, but without secular variations. Amplitudes of the periodic terms and their periods are calculated and discussed. © 2016, Pleiades Publishing, Ltd.


Gao P.,Northeast Normal University | Gao P.,Jilin University
Computers and Mathematics with Applications | Year: 2015

This paper is addressed to study the null controllability with constraints on the state for the reaction-diffusion system. We transform the problem into an equivalent null controllability problem with constraint on the control. Using a Carleman inequality adapted to the constraint, we prove the null controllability with constraints on the state for the reaction-diffusion system holds. © 2015 Elsevier Ltd.


Liu M.,Harbin Institute of Technology | Wang K.,Harbin Institute of Technology | Wang K.,Northeast Normal University | Wu Q.,Harbin Institute of Technology
Bulletin of Mathematical Biology | Year: 2011

Stochastic competitive models with pollution and without pollution are proposed and studied. For the first system with pollution, sufficient criteria for extinction, nonpersistence in the mean, weak persistence in the mean, strong persistence in the mean, and stochastic permanence are established. The threshold between weak persistence in the mean and extinction for each population is obtained. It is found that stochastic disturbance is favorable for the survival of one species and is unfavorable for the survival of the other species. For the second system with pollution, sufficient conditions for extinction and weak persistence are obtained. For the model without pollution, a partial stochastic competitive exclusion principle is derived. © 2010 Society for Mathematical Biology.


Liang Q.,Changchun University of Science and Technology | Xu H.,Northeast Normal University | Zhao J.,Changchun University of Science and Technology | Gao S.,Changchun University of Science and Technology
Sensors and Actuators, B: Chemical | Year: 2012

Micro humidity sensors are fabricated by radio-frequency sputtering ZnO and In 2O 3 thin films on SiO 2/Si substrates with interdigitated Pt signal electrodes. By adjusting the sensing film form, the micro sensors with a tiny area (1.36 mm × 0.55 mm) exhibit controllable humidity sensing properties. The best sample is obtained by sputtering two times of ZnO and one time of In 2O 3 on sensor active area (0.63 mm × 0.55 mm). The corresponding impedance changes by more than four orders of magnitude over the whole testing humidity range (from 11% to 95% relative humidity), and the response and recovery times are about 15 s and 40 s, respectively. High stability and good consistency are also observed based on the as-fabricated sensors. The improved and excellent humidity sensing properties are explained by the hetero junctions between ZnO and In 2O 3 thin films. High sensor performance and large-scale fabricating potentiality demonstrate that the micro humidity sensors are very promising devices for humidity detection which could be produced at industrial level. © 2012 Elsevier B.V. All rights reserved.


Zhou J.,Capital Normal University | Lu Z.,Capital Normal University | Shan G.,Northeast Normal University | Wang S.,Capital Normal University | Liao Y.,Capital Normal University
Biomaterials | Year: 2014

To compensate for the deficiencies of individual imaging modalities, lanthanide-based nanoparticles are ideal building blocks for multifunctional contrast agents. Herein, oleic acid-coated NaDyF4 nanorods (DyNPs) were synthesized by the hydrothermal method, and then coated with α-cyclodextrin (α-CD) and modified with gadolinium complex (Gd-DTPA) to obtain hydrophilic and functionalized nanoparticles (DyNPs-Gd). By loading the phosphorescent probe (iridium-complex) within the surface hydrophobic layer, the developed nanophosphors (DyNPs-Gd-Ir) could be further applied in phosphorescent cell labeling. The Dy in the host induces a high X-ray absorption ability for X-ray computed tomography (CT) and negative enhancement for T2-weighted magnetic resonance imaging (MRI), whereas positive contrast for T1-weighted MRI results from the Gd-DTPA. DyNPs-Gd-Ir has been successfully applied to T1-and T2-weighted MRI/CT invivo. Toxicity studies demonstrated that DyNPs-Gd-Ir exhibited low toxicity to living systems. Therefore, DyNPs-Gd-Ir could be a platform for next-generation contrast agents for T1- and T2-weighted MRI/CT/phosphorescence multimodal imaging. © 2013 Elsevier Ltd.


Fan Y.,Northeast Normal University
Open Cybernetics and Systemics Journal | Year: 2015

In contemporary society, so as to enhance Chinese basketball level, reform of Chinese basketball professionalization has been constantly deepened, while basketball clubs development is the internal impetus of Chinese basketball undertakings. The paper analyses specific situation of Chinese basketball clubs, and finds that most of Chinese sports clubs are sponsored and constructed by good corporate such as LuLu Group, Liaoning Bus Group, Wing On Company, Wanma Group and others, and they run through sports industry revenue, gate receipts and else; regarding Chinese basketball clubs coaches age, coaching time, experiences and others, it makes investigation and researches, and gets that though Chinese athletes basketball levels have some improvements, faculty is still deficient, which let Chinese basketball athletes technical levels not to be so high, amount of excellent athletes is not more, so China should increase investment in faculty so that propel to Chinese basketball development; by data sheet after logistic curve changing, it gets that the amount of Chinese basketball clubs will constantly increase in future years that provides training fields for Chinese more excellent athletes training and guarantees for their future development. © Yao Fan; Licensee Bentham Open.


Huang J.,Jilin University | Wang X.,Northeast Normal University | Li S.,Jilin University | Wang Y.,Jilin University
Applied Surface Science | Year: 2010

As a continuation of our work to develop catalysts with high activity for catalytic air wet oxidation process under mild conditions, degradation of wastewater containing 0.3 g/L Safranin-T (ST) by air oxidation over ZnO/MoO 3 nanotube catalyst was studied. It was found the decolorization efficiency and the chemical oxygen demand (COD) removal of ST reached above 98% and 95%, respectively, within 18 min at room temperature and atmospheric pressure. And the organic pollutants were totally mineralized to simple inorganic species such as HCO3 -, Cl- and NO3 -, while the total organic carbon (TOC) decreased 99.3%. The structure and morphology of the catalyst after ten cycling runs showed that the catalyst was stable under such operating condition and the leaching test showed negligible leaching effect. This ZnO/MoO3 nanotube is proved to be an active and stable heterogeneous catalyst in CWAO of ST under extremely mild conditions. © 2010 Elsevier B.V. All rights reserved.


Lu D.-Y.,Jilin Institute of Chemical Technology | Cui S.-Z.,Jilin Institute of Chemical Technology | Cui S.-Z.,Northeast Normal University
Journal of the European Ceramic Society | Year: 2014

The point defects and the structural and dielectric properties of Dy-doped BaTiO3 ceramics prepared at 1400°C were investigated. The solubility of Dy in the self-compensation mode was determined to be x=0.07 for (Ba1-xDyx)(Ti1-xDyx)O3, and no EPR signals associated with the Dy3+ Kramers ion or the Ba and Ti vacancies were detected using the electron paramagnetic resonance (EPR) technique. As x increases, the dielectric behavior changed from a first-order phase transition to a diffuse phase transition to a Y7R dielectric-temperature stability. A strong EPR signal at g=1.974, which is rare among rare-earth-doped BaTiO3 ceramics appeared unexpectedly in the single-phase (Ba1-xDyx)Ti1-x/4O3 ceramics with deliberately designed Ti vacancies. This signal was attributed to ionized Ba vacancy defects. A preference for the self-compensation mode of Dy3+ ions is responsible for the appearance of Ba vacancies. The real formula of the nominal (Ba1-xDyx)Ti1-x/4O3 is expressed as (Ba1-xDy3x/4)(Ti1-x/4Dyx/4)O3. In addition, the defect chemistry is discussed. © 2014 Elsevier Ltd.


Zhao T.,Harbin Institute of Technology | Ran Q.,Harbin Institute of Technology | Chi Y.,Northeast Normal University
Optics Communications | Year: 2014

Recently, optical asymmetric cryptosystem (OACS) has became the focus of discussion and concern of researchers. Some researchers pointed out that OACS was not tenable because of misunderstanding the concept of asymmetric cryptosystem (ACS). We propose an improved cryptosystem using RSA public-key algorithm based on existing OACS and the new system conforms to the basic agreement of public key cryptosystem. At the beginning of the encryption process, the system will produce an independent phase matrix and allocate the input image, which also conforms to one-time pad cryptosystem. The simulation results show that the validity of the improved cryptosystem and the high robustness against attack scheme using phase retrieval technique. © 2014 Elsevier B.V. All rights reserved.


Gao P.,Northeast Normal University
Computers and Mathematics with Applications | Year: 2015

This paper is addressed to study the null controllability with constraints on the state for the reaction-diffusion system. We transform the problem into an equivalent null controllability problem with constraint on the control. Using a Carleman inequality adapted to the constraint, we prove the null controllability with constraints on the state for the reaction-diffusion system holds. © 2015 Elsevier Ltd.


Li L.-F.,Washington University in St. Louis | Li L.-F.,Northeast Normal University | Olsen K.M.,Washington University in St. Louis
Current Topics in Developmental Biology | Year: 2016

Crop domestication provides a useful model system to characterize the molecular and developmental bases of morphological variation in plants. Among the most universal changes resulting from selection during crop domestication is the loss of seed and fruit dispersal mechanisms, which greatly facilitates harvesting efficiency. In this review, we consider the molecular genetic and developmental bases of the loss of seed shattering and fruit dispersal in six major crop plant families, three of which are primarily associated with seed crops (Poaceae, Brassicaceae, Fabaceae) and three of which are associated with fleshy-fruited crops (Solanaceae, Rosaceae, Rutaceae). We find that the developmental basis of the loss of seed/fruit dispersal is conserved in a number of independently domesticated crops, indicating the widespread occurrence of developmentally convergent evolution in response to human selection. With regard to the molecular genetic approaches used to characterize the basis of this trait, traditional biparental quantitative trait loci mapping remains the most commonly used strategy; however, recent advances in next-generation sequencing technologies are now providing new avenues to map and characterize loss of shattering/dispersal alleles. We anticipate that continued application of these approaches, together with candidate gene analyses informed by known shattering candidate genes from other crops, will lead to a rapid expansion of our understanding of this critical domestication trait. © 2016 Elsevier Inc.


Zhu T.,Northeast Normal University | Stojmenovic M.,Swinburne University of Technology
Ad-Hoc and Sensor Wireless Networks | Year: 2014

Recently, social-based approaches, which attempt to exploit the social behavior of mobile nodes to guide routing decisions, have attracted lots of attention in routing design of opportunistic networks. This paper presents a survey of the social characteristics shown in opportunistic mobile networks and emphasizes how to measure the social characteristics in time-vary contact graph. It discusses the typical social-based routing protocols and investigates the relationship among the routing performance, the mobility scenarios and routing protocols. This paper is concluded by discussing open questions and challenges in the design of social-based routing protocol between mobile devices. © 2014 Old City Publishing, Inc.


Li B.,Capital Normal University | Li B.,Northeast Normal University | Yu Z.-H.,Capital Normal University | Fei S.-M.,Capital Normal University
Scientific Reports | Year: 2013

Determining the quantum circuit complexity of a unitary operation is an important problem in quantum computation. By using the mathematical techniques of Riemannian geometry, we investigate the efficient quantum circuits in quantum computation with n qutrits. We show that the optimal quantum circuits are essentially equivalent to the shortest path between two points in a certain curved geometry of SU(3n). As an example, three-qutrit systems are investigated in detail.


Tian A.,Bohai University | Ying J.,Bohai University | Wang X.,Bohai University | Peng J.,Northeast Normal University
Inorganic Chemistry Communications | Year: 2011

A new Keggin POM-based compound, [Cd2(H2O) 2(btb)4(SiMo12O40)] (1) (btb = 1,4-bis(1,2,4-triazol-1-y1)butane), was synthesized under hydrothermal conditions. Compound 1 exhibits 2D wave-like metal-organic layers, which are further linked by Keggin [SiMo12O40]4- anions to construct a 3D framework containing two kinds of quadrate channels. The void left by channels induces an interesting two-fold interpenetrating structure. © 2010 Elsevier B.V. All rights reserved.


Guo W.,U.S. National Institutes of Health | Guo W.,Northeast Normal University | Shugart Y.Y.,U.S. National Institutes of Health
Human Heredity | Year: 2012

With the advent of sequencing technology opening up a new era of personal genome sequencing, huge amounts of rare variant data have suddenly become available to researchers seeking genetic variants related to human complex disorders. There is an urgent need for the development of novel statistical methods to analyze rare variants in a statistically powerful manner. While a number of statistical tests have already been developed to analyze collapsed rare variants identified by association tests in case-control studies, to date, only two FBAT tests-for-rare (described in the updated FBAT version v2.0.4) have applied collapsing methods analogously in family-based designs. For further research in this area, this study aims to introduce three new beta-determined weight tests for detecting rare variants for quantitative traits in nuclear families. In addition to evaluating the performance of these new methods, it also evaluates that of the two FBAT tests-for-rare, using extensive simulations of situations with and without linkage disequilibrium. Results from these simulations suggest that the four tests using beta-determined weights outperform the two collapsing methods used in FBAT (-v0 and-v1). In addition, both the linear combination method (detailed in the FBAT menu v2.0.4) and the multiple regression method (mixing LASSO and Ridge penalties) performed better than the other two beta-determined weight tests we proposed. Following testing and evaluation, we submitted four new beta-determined weight methods of statistical analysis in a computer program to the Comprehensive R Archive Network (CRAN) for general use. © 2012 S. Karger AG, Basel.


Zhao Y.-L.,CAS Changchun Institute of Applied Chemistry | Zhao Y.-L.,Northeast Normal University | Li Y.,Northeast Normal University | Li Y.,CAS Changchun Institute of Applied Chemistry | And 2 more authors.
Chemistry - A European Journal | Year: 2010

Chemical Equation presantation Suzuki-Miyaura coupling: We disclose a new strategy for phenol activation in the first Suzuki-Miyaura coupling of phenol derivatives activated by forming aryl bis(2-oxo-3-oxazolidinyl)phosphines as a highly efficient and broadly applicable methodology for the diverse synthesis of biaryls and heterobiaryls (see scheme). The use of readily available, stable NiCl2/dppp as the catalyst system also provides an important advance. © 2010 Wiley-VCH Verlag GmbH & Co. KGaA.


Guan Y.,Harbin Institute of Technology | Wang K.,Harbin Institute of Technology | Wang K.,Northeast Normal University
Mathematical and Computer Modelling | Year: 2013

In this paper, we study the structure of time scales under translations. We define several kinds of time scales such as the two-way translation invariant time scale and investigate their properties. Then we develop the almost periodic function theory on time scales, with examples given along the way. © 2012 Elsevier Ltd.


Huang W.,Northeast Normal University | Cao X.,University of California at San Diego | Biase F.H.,University of California at San Diego | Yu P.,University of California at San Diego | Zhong S.,University of California at San Diego
Proceedings of the National Academy of Sciences of the United States of America | Year: 2014

Both spatial characteristics and temporal features are often the subjects of concern in physical, social, and biological studies. This work tackles the clustering problems for time course data in which the cluster number and clustering structure change with respect to time, dubbed time-variant clustering. We developed a hierarchical model that simultaneously clusters the objects at every time point and describes the relationships of the clusters between time points. The hidden layer of this model is a generalized form of branching processes. A reversible-jump Markov Chain Monte Carlo method was implemented for model inference, and a feature selection procedure was developed. We applied this method to explore an open question in preimplantation embryonic development. Our analyses using single-cell gene expression data suggested that the earliest cell fate decision could start at the 4-cell stage in mice, earlier than the commonly thought 8- to 16-cell stage. These results together with independent experimental data from singlecell RNA-seq provided support against a prevailing hypothesis in mammalian development.


Sun W.,Northeast Normal University | Resco V.,University of Western Sydney | Williams D.G.,University of Wyoming
Plant, Cell and Environment | Year: 2012

Accurate estimates of the δ 13C value of CO 2 respired from roots (δ 13C R_root) and leaves (δ 13C R_leaf) are important for tracing and understanding changes in C fluxes at the ecosystem scale. Yet the mechanisms underlying temporal variation in these isotopic signals are not fully resolved. We measured δ 13C R_leaf, δ 13C R_root, and the δ 13C values and concentrations of glucose and sucrose in leaves and roots in the C 4 grass Sporobolus wrightii and the C 3 tree Prosopis velutina in a savanna ecosystem in southeastern Arizona, USA. Night-time variation in δ 13C R_leaf of up to 4.6±0.6‰ in S.wrightii and 3.0±0.6‰ in P.velutina were correlated with shifts in leaf sucrose concentration, but not with changes in δ 13C values of these respiratory substrates. Strong positive correlations between δ 13C R_root and root glucose δ 13C values in P.velutina suggest large diel changes in δ 13C R_root (were up to 3.9‰) influenced by short-term changes in δ 13C of leaf-derived phloem C. No diel variation in δ 13C R_root was observed in S.wrightii. Our findings show that short-term changes in δ 13C R_leaf and δ 13C R_root were both related to substrate isotope composition and concentration. Changes in substrate limitation or demand for biosynthesis may largely control short-term variation in the δ 13C of respired CO 2 in these species. The δ 13C value of CO 2 respired from roots (δ 13C R_root) and leaves (δ 13C R_leaf) is important for tracing C fluxes at the ecosystem scale, however the mechanisms underlying temporal variation in these isotopic signals are not fully resolved. We tested hypotheses that short-term variation in δ 13C R_leaf and δ 13C R_root are regulated by the δ 13C values of primary respiratory substrates and changes in apparent respiratory fractionation associated with variation in substrate availability. We found that nighttime decreasing in δ 13C R_leaf value is controlled by substrate availability associated changes in respiratory apparent fractionation but not δ 13C of primary respiratory substrates; however, diurnal variation in Prosopis velutinaδ 13C R_root is likely influenced by both changes in δ 13C of primary respiratory substrates and variation in respiratory apparent fractionation. These findings are important for incorporating short term variation in δ 13C R_leaf and δ 13C R_root into the interpreting of δ 13C value of ecosystem-atmosphere CO 2 exchange and partitioning of net ecosystem CO 2 exchange into its components. © 2011 Blackwell Publishing Ltd.


Li G.,Shenyang University | Wang C.,Northeast Normal University | Zhang X.,Shenyang University
Journal of Coordination Chemistry | Year: 2013

Two supramolecular isomers, {[Cd2(pda)2(1,10'-phen) 2]H2O}n (1) and {[Cd2(pda)2(1,10'- phen)2]4-H2O}n (2) (1,10'-phen = 1,10-phenanthroline, pda = phenylenediacrylate dianion), have been synthesized and characterized by single-crystal X-ray analysis. Complex 1 exhibits a 3D network constructed from 1D rod-shaped secondary building units, while 2 shows a 3D, twofold interpenetrated framework. There exists a reversible transformation between the pair of isomers: when yellow block crystals of 1 are treated under microwave irradiation, colorless plate crystals of 2 are formed; in turn, if crystals of 2 are dissolved in water and left undisturbed about two weeks at room temperature, crystals of 1 reappear. Fluorescence properties of 1 and 2 have also been studied. © 2013 Taylor & Francis.


Pu F.,CAS Changchun Institute of Applied Chemistry | Wang E.,Northeast Normal University | Jiang H.,Jilin University | Ren J.,CAS Changchun Institute of Applied Chemistry
Molecular BioSystems | Year: 2013

Angiogenesis is the process of new blood vessel formation from pre-existing ones. Angiogenic factors contribute to neovascularization that takes place in angiogenesis-dependent diseases, including cancer. Inhibiting the activity of the angiogenic factors to block the angiogenesis pathways is the current strategy of cancer therapy. Basic fibroblast growth factor (bFGF) is regarded as one of the most important angiogenic factors. Herein, we selected polyoxometalates (POMs) with different structures to study the interactions between bFGF and POMs. The results show that POMs could bind to the protein with high affinity, causing detectable changes in conformation and biophysical properties of protein. In addition, POMs could effectively inhibit the cell proliferation induced by bFGF. Significantly, we found that the structure, size and composition of POMs play a key role in the interactions between bFGF and POMs. This study will be meaningful for future screening and design of polyoxometalate-based anticancer drugs. © 2013 The Royal Society of Chemistry.


Xu X.,Liaoning University | Zhang X.,Liaoning University | Liu X.,Liaoning University | Wang L.,Liaoning University | Wang E.,Northeast Normal University
CrystEngComm | Year: 2012

Two fascinating 3D entangled coordination polymers, [Ni 5(pda) 5(bpp) 5]·12H 2O (1) and [Cd 2(pda) 2(1,10′-phen) 2]·4H 2O (2) (pda = phenylenediacrylate dianion; bpp = 1,3-bis(4-pyridyl) propane; 1,10′-phen = 1,10′-phenanthroline), have been successfully synthesized and characterized by single-crystal X-ray analysis. In complex 1, two 4 4-sql nets interweave in parallel and give rise to a 2-fold interpenetrated layer (2D → 2D). In addition, each layer interlocks two other layers, one above and one below (2D → 3D). This results in an interesting 3D coordination polymer containing interpenetration and polycatenation at the same time. Complex 2 exhibits a 2D → 3D polythreaded framework based on 2D 4 4-sql motifs with side arms. If π-π interactions are taken into account, the resulting structure displays a 2-fold interpenetrated 3D α-Po network. Interestingly, if crystals of 2 are dissolved in water and left undisturbed for about two weeks at room temperature, its supramolecular isomer [Cd 2(pda) 2(1,10′-phen) 2]·H 2O (3) is formed. On the contrary, when yellow block crystals of 3 are treated under microwave conditions, colorless plate crystals of 2 reappear. This means that there exists a reversible transformation process between 2 and its isomer 3. Furthermore, the fluorescence properties of 2 have been studied. © The Royal Society of Chemistry 2012.


Liu M.,Harbin Institute of Technology | Wang K.,Harbin Institute of Technology | Wang K.,Northeast Normal University
Mathematical and Computer Modelling | Year: 2012

This is a continuation of our paper [M. Liu, K. Wang, Asymptotic properties and simulations of a stochastic logistic model under regime switching, Math. Comput. Modelling 54 (2011) 2139-2154]. First, we establish the sufficient conditions for stochastic permanence which are much weaker than those in our previous paper. Then we study some new asymptotic properties of this model. The lower-growth rate and the upper-growth rate of the positive solution are investigated. The superior limit of the average in time of the sample path of the solution is also estimated. Finally, some simulation figures are introduced to illustrate the main results. Some recent investigations are improved and generalized. © 2011 Elsevier Ltd.


Yang G.,Jilin University | Yang G.,Northeast Normal University | Wang Y.,Jilin University | Ma Y.,Jilin University
Journal of Physical Chemistry Letters | Year: 2014

The Li-air battery with the specific energy exceeding that of a Li ion battery has been aimed as the next-generation battery. The improvement of the performance of the Li-air battery needs a full resolution of the actual discharge products. Li2O2 has been long recognized as the main discharge product, with which, however, there are obvious failures on the understanding of various experimental observations (e.g., magnetism, oxygen K-edge spectrum, etc.) on discharge products. There is a possibility of the existence of other Li-O compounds unknown thus far. Here, a hitherto unknown Li3O4 compound as a discharge product of the Li-air battery was predicted through first-principles swarm structure searching calculations. The new compound has a unique structure featuring the mixture of superoxide O2 - and peroxide O2 2-, the first such example in the Li-O system. The existence of superoxide O 2 - creates magnetism and hole-doped metallicity. Findings of Li3O4 gave rise to direct explanations of the unresolved experimental magnetism, triple peaks of oxygen K-edge spectra, and the Raman peak at 1125 cm-1 of the discharge products. Our work enables an opportunity for the performance of capacity, charge overpotential, and round-trip efficiency of the Li-air battery. © 2014 American Chemical Society.


Gao P.,Northeast Normal University
Mathematics of Control, Signals, and Systems | Year: 2016

In this study, we first establish an identity for a stochastic fifth-order Kawahara operator, and then, applying this identity, we obtain two global Carleman estimates for linear stochastic Kawahara equation. Based on these estimates, we obtain two types of unique continuation property for linear stochastic Kawahara equation. © 2016, Springer-Verlag London.


Tong H.,Beihua University | Liu X.,Northeast Normal University | Tian D.,Beihua University | Sun X.,Beihua University
World Journal of Microbiology and Biotechnology | Year: 2013

Tricholoma matsutake, a high-class edible mushroom in China, has been regarded as famous foods and biopharmaceutical materials with a great deal of interest. In the previous investigations, researchers believe the water-soluble polysaccharide β-glucan is the major active component of T. matsutake, which displays various biological activities. In the present study, two novel alkali-extracted polysaccharide fractions, TM-APS-1 and TM-APS-2, were isolated from the fruit bodies of T. matsutake by DEAE-cellulose and Sepharose CL-6B columns on ÄTKA explorer chromatography system. Their chemical and physical characteristics and radical scavenging capacity were valuated, including chemical methods, GC, HPLC, scavenging activity against DPPH radicals, superoxide radicals, hydroxyl radicals, and chelating ability. The results showed that TM-APS-1 and TM-APS-2 exhibited significantly antioxidant activity at a concentration-dependent manner. The alkali-extracted polysaccharide fractions from T. matsutake can be developed to be novel functional food or pharmaceutical products with antioxidant effects. © 2012 Springer Science+Business Media Dordrecht.


Li L.-S.,Northeast Normal University
Monthly Notices of the Royal Astronomical Society | Year: 2012

In this paper, using the expansion of the true anomaly, we examine how the time variation of the gravitational constant influences the variation of the orbital elements of planets. The theoretical results show that the semimajor axis exhibits secular and periodic variation in the first order for. The eccentricity exhibits periodic variation, but there is no secular variation in the first and second orders for. The longitude of perihelion and the mean longitude at the epoch exhibit periodic variation but no secular variation in the first order for. However, they do exhibit secular variation in the second order for. The inclination and ascending node exhibit no variation. The bounds on the values of the secular variation of the semimajor axis and the orbital period, which result from the time variation of the gravitational constant, are estimated for five planets. The results are discussed and conclusions are made. © 2011 The Author Monthly Notices of the Royal Astronomical Society © 2011 RAS.


Zeng Z.,Northeast Normal University
Computers and Mathematics with Applications | Year: 2011

In this paper, a modified delayed predatorprey system with stage structure for predator is proposed and studied, which generalizes and incorporates as special cases some known models. With the help of continuation theorem based on the Gaines and Mawhin coincidence degree theory, we investigate the existence of periodic solutions for the proposed delayed predatorprey system with stage-structured predator and two kinds of functional responses (called Holling III functional response and BeddingtonDeAngelis functional response) on time scales. In particular, when the time scale is chosen as the set of the real numbers or the integers, the existence of the periodic solutions of the corresponding continuous-time and discrete-time models follows. © 2011 Elsevier Ltd. All rights reserved.


Zhao Q.,Northeast Normal University
WIT Transactions on Information and Communication Technologies | Year: 2014

In this research, the influence of high level university athletes' lack of cultural education structure and functions on the ecosystem of universities, and the influence of current high level athletes' lack of management system on the athletes' growth are explored from the perspective of ecosystem theory to provide reference for the sustained development of high level university athletes. © 2014 WIT Press.


Chang X.,Northeast Normal University | Chang X.,Jilin University
Journal of Mathematical Physics | Year: 2013

This paper is devoted to a time-independent fractional Schrödinger equation of the form (-δ)su+V(x)u=f(x,u)inRN, where N ≥ 2, s ∈ (0, 1), (-δ)s stands for the fractional Laplacian. We apply the variational methods to obtain the existence of ground state solutions when f(x, u) is asymptotically linear with respect to u at infinity. © 2013 AIP Publishing LLC.


Zhou M.,Northeast Normal University | Wang H.-L.,Los Alamos National Laboratory | Guo S.,Peking University
Chemical Society Reviews | Year: 2016

One of the critical issues in the industrial development of fuel cells (e.g., proton exchange membrane fuel cells, direct methanol fuel cells and biofuel cells) is the high cost, serious intermediate tolerance, anode crossover, sluggish kinetics, and poor stability of the platinum (Pt) as the preferred electrocatalysts for the oxygen reduction reaction (ORR) at the cathode. The development of novel noble-metal-free electrocatalysts with low cost, high activity and practical durability for ORR has been considered as one of the most active and competitive fields in chemistry and materials science. In this critical review, we will summarize recent advances on engineering advanced carbon nanomaterials with different dimensions for the rational design and synthesis of noble-metal-free oxygen reduction electrocatalysts including heteroatom-doped carbon nanomaterials, transition metal-based nanoparticle (NP)-carbon nanomaterial composites and especially the stable iron carbide (Fe3C)-based NP-carbon nanomaterial composites. Introducing advanced carbon nanomaterials with high specific surface area and stable structure into the noble-metal-free ORR field has not only led to a maximized electrocatalyst surface area for the electron transfer but also resulted in enhanced electrocatalyst stability for long-term operation. Therefore, the rational design and synthesis of noble-metal-free electrocatalysts based on heteroatoms, transition metal-based NPs and Fe3C-based NP functionalized carbon nanomaterials are of special relevance for their ORR applications, and represents a rapidly growing branch of research. The demonstrated examples in this review will open new directions on designing and optimizing advanced carbon nanomaterials for the development of extremely active and durable earth-abundant cathodic catalysts for fuel cell applications. © The Royal Society of Chemistry 2016.


The secular effects of the electric induction drag on the orbit of a charged satellite moving in the ionosphere are examined by the method of average values. The first solutions are obtained under the assumption of non-rotation of the Earth; the second solutions are obtained assuming rotation of the Earth. In the first case the semi-major axis exhibits secular variation, but the other orbital elements exhibit no secular variation. In the second case both semi-major axis and eccentricity exhibit secular variation, but the other orbital elements exhibit no secular variation. It can be shown that the semi-major axis is contracted due to the action of the electric induction drag if the satellite has enough charge in the ionosphere. The eccentricity is decreased gradually with time, but its variation is very small for the case of a rotating Earth. An example is presented in which the secular effects of the electric induction drag on the orbits of a charged satellite are calculated. The numerical results are given in Table 1 and a discussion of them is presented in Table 2. © 2015, The Author(s).


Sun J.,University of Michigan | Cui J.,Tianjin Medical University | He Q.,Tianjin Medical University | Chen Z.,Northeast Normal University | And 3 more authors.
Molecular Aspects of Medicine | Year: 2015

To maintain copious insulin granule stores in the face of ongoing metabolic demand, pancreatic beta cells must produce large quantities of proinsulin, the insulin precursor. Proinsulin biosynthesis can account for up to 30-50% of total cellular protein synthesis of beta cells. This puts pressure on the beta cell secretory pathway, especially the endoplasmic reticulum (ER), where proinsulin undergoes its initial folding, including the formation of three evolutionarily conserved disulfide bonds. In normal beta cells, up to 20% of newly synthesized proinsulin may fail to reach its native conformation, suggesting that proinsulin is a misfolding-prone protein. Misfolded proinsulin molecules can either be refolded to their native structure or degraded through ER associated degradation (ERAD) and autophagy. These degraded molecules decrease proinsulin yield but do not otherwise compromise beta cell function. However, under certain pathological conditions, proinsulin misfolding increases, exceeding the genetically determined threshold of beta cells to handle the misfolded protein load. This results in accumulation of misfolded proinsulin in the ER - a causal factor leading to beta cell failure and diabetes. In patients with Mutant INS-gene induced diabetes of Youth (MIDY), increased proinsulin misfolding due to insulin gene mutations is the primary defect operating as a "first hit" to beta cells. Additionally, increased proinsulin misfolding can be secondary to an unfavorable ER folding environment due to genetic and/or environmental factors. Under these conditions, increased wild-type proinsulin misfolding becomes a "second hit" to the ER and beta cells, aggravating beta cell failure and diabetes. In this article, we describe our current understanding of the normal proinsulin folding pathway in the ER, and then review existing links between proinsulin misfolding, ER dysfunction, and beta cell failure in the development and progression of type 2, type 1, and some monogenic forms of diabetes. © 2015 Elsevier Ltd. All rights reserved.


Yu H.,Anshan Normal University | Liao P.,Northeast Normal University
Tetrahedron Letters | Year: 2016

A novel DBSA-catalyzed Friedel-Crafts alkylation of cyclic ketene dithioacetals, internal alkenes with highly nucleophilic carbon atom adjacent to the electron-withdrawing group, with alcohols in water has been developed. The reaction is efficient in the presence of catalyst loading as low as 10 mol % in water at reflux, and a wide range of alkylated ketene dithioacetals are synthesized in excellent yields. © 2016 Elsevier Ltd. All rights reserved.


Gao H.,CAS Changchun Institute of Applied Chemistry | Gao H.,Jilin University | Li Y.,Northeast Normal University | Zhou Y.-G.,CAS Changchun Institute of Applied Chemistry | And 2 more authors.
Advanced Synthesis and Catalysis | Year: 2011

We present a highly active, inexpensive, universally applicable, and markedly stable [1,3-bis(diphenylphosphino)propane]nickel(II) chloride [Ni(dppp)Cl2] catalyst that is capable of effecting the Suzuki-Miyaura cross-coupling of the inherently less reactive but readily available aryl tosylates and mesylates with only 1amol% loading and in the absence of extra supporting ligand. Under the optimized reaction conditions, cross-coupling of a wide range of activated, non-activated, and deactivated, as well as sterically hindered and heteroaromatic substrates (36 examples) could proceed efficiently to afford the coupled products in 53-99% yields. Consequently, the results presented in this work provide a significant advance in Suzuki-Miyaura cross-coupling in terms of generality, practicality, and cost which are key concerns in recent research regarding transition metal-catalyzed cross-couplings. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


Li L.-S.,Northeast Normal University
Astrophysics and Space Science | Year: 2011

The influence of the gravitational radiation damping on the time of periastron passage of a binary system is examined. It turns out that the gravitational radiation damping yields secular, periodic and mixed periodic variation of the time of periastron passage. As a consequence, the crossing of the periastron occurs earlier (advance) at each revolution. A numerical estimation of such an effect for eight binary stars is given. The results obtained are discussed. © 2011 Springer Science+Business Media B.V.


Liu X.,Northeast Normal University | Wang C.-Z.,Iowa State University
RSC Advances | Year: 2016

We present a systematic study of Mn clusters on graphene by first-principles calculations. We show that the growth of Mn on graphene follows a three-dimensional (3D) mode. Both adsorption and attachment energies show that (Mn)3 and (Mn)6 on graphene are energetically favorable in the size range (Mn)1-7. Moreover, the larger formation energy for Mn clusters on graphene implies that the incoming Mn atoms are likely to nucleate and grow into bigger and bigger Mn clusters on graphene. The magnetic moments of (Mn)1,5,7 on graphene are enhanced by 11%, 186%, and 26% from their values at free-standing clusters, respectively. By contrast, the net magnetic moment of (Mn)2,3,4,6 on graphene is reduced from that of the corresponding free-standing clusters. The origin of the magnetic moment changes can be attributed to the charge transfer within the Mn clusters and between the clusters and graphene upon adsorption. © The Royal Society of Chemistry 2016.


Gao J.,Northeast Normal University
BioTechnology: An Indian Journal | Year: 2014

More and more people keen on football, how to improve shooting success rate troubles broad football lovers. The paper uses probabilities statistics, establishes two-dimensional probability model, judges the most beneficial incidence orientation to provide references for football lovers. Firstly establish space coordinate system in the plane that goal and field locate, it is clear that shooting success rate shows two-dimensional probability distribution. Secondly, analyze each point of field shooting success rate when there is no goalkeeper, and make shooting equivalent success rate curve graph. Analyze shooting success rate in case there is a goalkeeper, establish goalkeeper saving success probability model, combine with goalkeeper saving success rate and shooting success rate in case no goalkeeper, then it can get player shooting success rate in each point of field in case there is a goalkeeper. Use MATLAB software, then it can draw equivalent success rate curve, it is most easily to shoot in the fan shaped area that within 20m nearby the goal, especially for the position in the right ahead of goal. © 2014 Trade Science Inc. - INDIA.


Yuan G.,Northeast Normal University
Inverse Problems | Year: 2015

In this paper, we derive a Carleman estimate for a stochastic wave equation. Then we apply the Carleman estimate to solve an inverse source problem of determining two kinds of sources simultaneously for a stochastic wave equation. Our main result is a uniqueness result for the inverse source problem. © 2015 IOP Publishing Ltd.


Jin Y.H.,Institute of Grassland science | Jin Y.H.,Northeast Normal University | Zhou D.W.,CAS Changchun Northeast Institute of Geography and Agroecology | Jiang S.C.,Institute of Grassland science
Agricultural Water Management | Year: 2010

Water deficits and unusually warm soil temperatures can adversely affect conventional ridge sown systems. Increasingly serious water and temperature issues associated with global climate change may be problematic in the future, particularly in semiarid regions. This study explored the soil water and crop yield benefits of switching the sowing location of corn from ridges to furrows. Experiments were conducted over three years. Corn was grown in shallow furrow (SF) and deep furrow (DF) sown treatments until the V8 stage (eight visible leaf collars). New ridges were then built over the existing furrows. Grain yield was found to be higher in the SF and DF sown treatments than in a conventional ridge sown treatment (CR), especially in drought years. Switching sowing position from ridge to furrow could increase corn yield, directly, by improving soil moisture early in the growing season and, indirectly, by stimulating the growth of resource-capturing organs (e.g., leaves and roots). This simple and efficient approach to crop production in semiarid climates may be practical for the management of numerous agricultural systems, particularly those that are resource-limited, with greater vulnerability to the effects of global climate change. © 2009 Elsevier B.V. All rights reserved.


Qu X.,Monash University | Li X.,Inner Mongolia University | Zheng Y.,Northeast Normal University | Ren Y.,Florida State University | And 4 more authors.
American Journal of Pathology | Year: 2014

Transforming growth factor-β (TGF-β) promotes tissue fibrosis via receptor-mediated phosphorylation of the receptor-activated Smad2/3, together with Smad4. Of these, Smad3 plays a major profibrotic role in mouse models of tissue fibrosis. Transcriptional activity of the Smad3 protein is regulated by phosphorylation of residues in the C-terminal domain and the linker region. Herein, we examined the role of a novel phosphorylation site within the MH2 domain (T388) in the regulation of Smad3 activity. Confocal microscopy using an Smad3 phosphorylated T388-specific antibody identified phosphorylation of Smad3 T388 in myofibroblasts and tubular epithelial cells in human focal and segmental glomerulosclerosis and mouse models of unilateral ureteric obstruction and diabetic nephropathy, whereas phosphorylated T388 was largely absent in normal kidney. In vitro, TGF-β1 induced phosphorylation of Smad3 T388 in a biphasic pattern. A point mutation of T388/V in an Smad3 construct demonstrated that phosphorylation of T388 promotes Smad3 binding to Smad4 and CDK8, but was not necessary for nuclear translocation. Furthermore, T388 phosphorylation was required for TGF-β-induced collagen I gene promoter activity and extracellular matrix production in cultured fibroblasts. In conclusion, our study identifies phosphorylation of T388 in the Smad3 MH2 domain as an important mechanism that regulates the profibrotic TGF-β/Smad3 signaling pathway, which has direct relevance to human and experimental fibrotic kidney disease.


Sun L.,Jilin University | Xing H.,Northeast Normal University | Liang Z.,Jilin University | Yu J.,Jilin University | Xu R.,Jilin University
Chemical Communications | Year: 2013

A zeolitic metal-organic framework with a SOD topology, (Et 2NH2)[In(BCBAIP)]·4DEF·4EtOH (H 4BCBAIP: 5-(bis(4-carboxybenzyl)amino)isophthalic acid) (1), has been constructed by a 4 + 4 synthetic strategy from tetrahedral organic building units and In3+ ions. Compound 1 could adsorb organic dyes and be used as a light-harvesting antenna. © 2013 The Royal Society of Chemistry.


Yu H.,Anshan Normal University | Liao P.,Northeast Normal University
Chemistry Bulletin / Huaxue Tongbao | Year: 2013

In the presence of 4-dodecylbenzenesulfonic acid, the dihydro-1, 4-dithiin and dihydro-1, 4-dithiepin derivatives have been synthesized efficiently through the condensation of odorless and stable 1-(1, 3-dithiolan/1, 3-dithian-2-ylidene)-propan-2-one and α-brominated ketones or benzoin under refluxing in water. It is noteworthy that the odor of thiols were not be perceived during both the reaction and workup.


Huang Y.,Iowa State University | Huang Y.,Northeast Normal University | Martin L.M.,Iowa State University | Isbell F.I.,University of Minnesota | Wilsey B.J.,Iowa State University
Basic and Applied Ecology | Year: 2013

Community persistence, or the ability of a community to maintain species composition and diversity through time, is a component of stability that is important to restoration. We ran a biodiversity-ecosystem functioning experiment for three years, and then stopped weeding it for 5-6 years, which allowed us to test whether increased plant species diversity and dissimilarity in height would lead to increased community persistence in the face of high invasion pressure by non-native species. Our approach was unique in that the experiment varied richness (one or four species) and evenness (three levels plus monocultures of the dominant species) using two separate dissimilarity types (having all tall species or having tall and short species combined) in six spatiotemporal blocks. Persistence was quantified as to how well positive productivity-diversity relationships, proportion of planted native species, and species richness remained unchanged over time. Thus, high persistence values indicate low levels of invasion and local extinction. We found that the positive relationship between diversity measures and productivity persisted after cessation of weeding. The proportion of planted species was 32% higher in mixture than in monoculture plots, indicating that monocultures were more heavily invaded by non-native species. Reduced evenness did not affect persistence measures in plots with dissimilar heights, but measures declined linearly with decreased evenness in plots with all tall species. Our results suggest that (1) persistence-diversity relationships are likely to vary with the traits of species becoming rare and going extinct, and (2) it is important to restore higher species diversity in restoration projects to favor the long-term persistence of planted species. © 2013 Gesellschaft fU{double grave}r U{double grave}kologie.


Zheng L.,Northeast Normal University
Biomedical Research (India) | Year: 2016

This paper adopts literature, experiment, and mathematical statistics, and conducts aerobic Lactate threshold (LT) intensive training for 30 cases of obese female college students without sports training history, medical history, or sports contraindications. For the high obesity rate of female college students, this paper aims to explore secure and effective weight loss plan for this group based on experimental research. After 15 weeks aerobic LT intensive training, the results are as follows: (1) The body composition of the obese female college students tends to be normal, which means the goal of weight loss is fulfilled (P<0.05). (2) The function index in the oxygen transport system of obese female college students is significantly improved, as well as respiratory and circulatory function (P<0.05). (3) The blood sugar, blood fat, and serum insulin level of obese female college students are significantly improved and tend to be normal (P<0.05). The exercise load method can decompose the fat of obese female college students and increase Lean body mass (LBM), making body composition gradually to a normal level. © 2016, Scientific Publishers of India. All rights reserved.


Genheden S.,Lund University | Mikulskis P.,Lund University | Hu L.,Lund University | Hu L.,Northeast Normal University | And 3 more authors.
Journal of the American Chemical Society | Year: 2011

Continuum solvation methods are frequently used to increase the efficiency of computational methods to estimate free energies. In this paper, we have evaluated how well such methods estimate the nonpolar solvation free-energy change when a ligand binds to a protein. Three different continuum methods at various levels of approximation were considered, viz., the polarized continuum model (PCM), a method based on cavity and dispersion terms (CD), and a method based on a linear relation to the solvent-accessible surface area (SASA). Formally rigorous double-decoupling thermodynamic integration was used as a benchmark for the continuum methods. We have studied four protein-ligand complexes with binding sites of varying solvent exposure, namely the binding of phenol to ferritin, a biotin analogue to avidin, 2-aminobenzimidazole to trypsin, and a substituted galactoside to galectin-3. For ferritin and avidin, which have relatively hidden binding sites, rather accurate nonpolar solvation free energies could be obtained with the continuum methods if the binding site is prohibited to be filled by continuum water in the unbound state, even though the simulations and experiments show that the ligand replaces several water molecules upon binding. For the more solvent exposed binding sites of trypsin and galectin-3, no accurate continuum estimates could be obtained, even if the binding site was allowed or prohibited to be filled by continuum water. This shows that continuum methods fail to give accurate free energies on a wide range of systems with varying solvent exposure because they lack a microscopic picture of binding-site hydration as well as information about the entropy of water molecules that are in the binding site before the ligand binds. Consequently, binding affinity estimates based upon continuum solvation methods will give absolute binding energies that may differ by up to 200 kJ/mol depending on the method used. Moreover, even relative energies between ligands with the same scaffold may differ by up to 75 kJ/mol. We have tried to improve the continuum solvation methods by adding information about the solvent exposure of the binding site or the hydration of the binding site, and the results are promising at least for this small set of complexes. © 2011 American Chemical Society.


Liu C.-G.,Northeast Dianli University | Guan X.-H.,Northeast Dianli University | Su Z.-M.,Northeast Normal University
Journal of Theoretical and Computational Chemistry | Year: 2012

In this paper, electronic structures and third-order nonlinear optical (NLO) properties of a series of PtPt bond-containing metal complexes have been calculated by using the density functional theory (DFT) combining with the sum-over-states (SOS) method. In order to check the reliability of this method, the electron correlations and basis sets have been compared. Our calculated results show that introduction of electron donor, thiophene ring and lengthing of organic conjugated ligand can enhance third-order NLO responses. The electronic structure analysis shows that the [PtPt(H 2P(CH 2)PH 2) 2] fragment displays strong electron-withdrawing character in these systems. Meanwhile, the third-order NLO response of Pt-Pt bond also has been estimated by using TDDFTSOS method. An enhancement of third-order NLO response has been observed because of the introduction of the PtPt bond. This is mainly due to the intense and low-lying metal-to-ligand charge transfer (MLCT) and intraligand (IL) CT transitions. © 2012 World Scientific Publishing Company.


Cai D.,Wuhan Institute of Technology | Cai D.,Jilin University | Yin M.,Northeast Normal University
Knowledge-Based Systems | Year: 2012

Landmarks have been successfully employed in sequential planning, especially in the design of heuristic functions. However, little attention has been paid on exploiting landmarks in parallel planning. Here we propose a way to use the information of landmarks in SAT based planning, which is a successful framework for generating parallel plans. Specifically, we propose a way to encode landmarks and their orderings of a planning task into clauses, which are then integrated into the encoding of the task. We call those clauses landmark clauses. Landmark clauses are additional constraints that have the potential to help a SAT solver prune its search space considerably. However, for modern SAT solvers that employ more advanced reasoning or clause learning techniques, the effect of landmark clauses could be not intuitive. Therefore, our major work is giving examples and further identifying conditions under which landmark clauses are not logically redundant. We identify types of landmark clauses that cannot be derived by unit propagation, binary resolution or hyper resolution. Importantly, we prove that not all landmark clauses are redundant in terms of the UP-redundancy that was proposed by Sideris and Dimopoulos in 2010. We also conducted experiments on benchmarks from International Planning Competitions. The results show that MiniSat, a state-of-the-art SAT solver with the clause learning ability, with landmark clauses can be more efficient than it without landmark clauses on some hard planning problems. Therefore, we argue that landmarks and their orderings have promising effects in speeding up SAT based planning methods. © 2012 Elsevier B.V. All rights reserved.


Si Y.,Jilin Agricultural University | Yang G.,Northeast Normal University
Molecular Physics | Year: 2012

We have investigated the electronic transition, chiroptical properties, and the second-order nonlinear optical (NLO) properties of eight novel chiral diborate compounds and elucidated structure-property relationships from the micromechanism. These compounds show calculated first hyperpolarizabilities (β) ranging from 2738.52 to 83976.4510 33esu, which means that subtle structural modifications can substantially enhance the first hyperpolarizability. The cooperativity of intramolecular charge transfer and an effective way to enhance the NLO response were also systemically investigated. The linear correlation between the first hyperpolarizability and the inverse of the electronic transition energy suggests that the electronic transition energy plays a key role in determining the NLO response. These compounds have the potential to be excellent second-order NLO materials from the standpoint of the large values, high transparency and the intrinsic non-centrosymmetry. The electronic transition and chiroptical properties have been assigned and analysed. The main UV-visible absorption features are best described as π → π * transitions. Moreover, the effects of different functionals and basis sets on the first hyperpolarizability were investigated. © 2012 Copyright Taylor and Francis Group, LLC.


Zheng H.,Northeast Normal University
BioTechnology: An Indian Journal | Year: 2014

Take Liu Xiang specific performance prediction as research object, on the basis of fuzzy neural network method, it collects 70 times' Liu Xiang 110m hurdle performance in 2000 to 2010 composing data set, establish fuzzy neural network prediction model after normalization processing of the previous 60 times' performance, and make prediction on final 10 times' performance. Result shows that the fuzzy neural network prediction method is effective, Liu Xiang 110m hurdle performance prediction is basic correct, it can provide theoretical reference for its training and even other excellent hurdlers' training. © 2014 Trade Science Inc. - INDIA.


Wang P.,University of Alberta | Wang P.,Northeast Normal University | Stieglitz T.,University of Alberta | Zhou D.W.,CAS Changchun Northeast Institute of Geography and Agroecology | Cahill Jr. J.F.,University of Alberta
Functional Ecology | Year: 2010

The ability to suppress neighbour growth and the ability to withstand growth suppression are widely viewed as two forms of competition, competitive effect and competitive response. 2. We conducted a greenhouse experiment to determine whether these two forms of competition were functionally linked, and to determine which plant traits are associated with effect and response competitive abilities among seedlings of 22 perennial North American prairie species. We further explored the trait-function relationship by growing plants under different soil fertilities and with different neighbour species. 3. To determine competitive abilities, we used a phytometer approach with two phytometer species: Poa pratensis and Achillea millefolium grown in competition with each of the 22 focal species under low and high fertility. Root and shoot morphological traits were measured and principal component analyses were used to reduce the dimensionality of the data. Three axes were extracted, which roughly corresponded to size, root and shoot architecture. 4. The hierarchy of competitive effect ability of the target species did not vary with either soil fertility or neighbour identity, while the hierarchies of competitive response abilities were highly variable among the treatments. Competitive effect ability was closely associated with size-related traits under high nutrient conditions, and with root-related traits under low nutrient conditions. In contrast, few plant traits axes were related to competitive response. 5. These findings indicate significant differences between competitive effect and response ability. We suggest competitive effect ability is a consistent trait of a species, linked to specific plant traits. In contrast, we found little evidence to support the idea that competitive response ability is itself a species trait, and instead it appears this may be simply a collection of different ways of avoiding or tolerating competition and/or low nutrient conditions. Supporting this argument was a lack of any consistency in which traits were associated with competitive response ability. 6. We recognize the limitations of a single study of seedlings under greenhouse conditions. However, we suggest these findings indicate a need to critically examine current assumptions about plant competition, how it is defined, and the traits which control a species' competitive ability. © 2009 British Ecological Society.


Zhang Y.,Northeast Normal University
BioTechnology: An Indian Journal | Year: 2014

The paper researches on football game football goal dangerous regions, utilizes known football knowledge, it establishes football goal dangerous regions one dimension normal and two dimensional normal distribution model, and uses MATLAB software to solve and simulate established model. Calculate goal different positions' threat level, and draws most dangerous region. Firstly, in case no goalkeepers here let same player shoot in different regions of field, and research field's different points' threat level to goal. By statistical researching, shooting success points in the whole football field is in normal distribution, and finally uses MATLAB to simulate. Secondly, in case it has goalkeeper, research same player shooting probabilities in different points of field and goalkeeper success save odds, finally use Matlab to simulate. By calculation, it proves when player quality strengthened, threaten to goal is obvious increasing, and dangerous region expands. © 2014 Trade Science Inc. - INDIA.


Zhang Y.,Northeast Normal University
BioTechnology: An Indian Journal | Year: 2014

In order to make comprehensive evaluation on Chinese football teams strength, the paper analyzes Chinese 12 football teams' performances in year 2012-2013national football first division team league matches, establishes four models from simple to complex, from rough to relative accurate, firstly successive calculate each team total score, and meanwhile make statistics of each team number of games, rank total score /number of games, obtained result can approximately be used as each team ranking. Secondly, according to game data, establish a 12×12 digital matrix A =(aij)1×12, use C++ programming, input obtained matrix, solve Hamilton opening path, and rank it. In the following, use three-point to calculate any i team and j team (i ≠ j) score ratio bij, from which bij=1, and get score matrix B =(bij)12×12, solve score matrix maximum feature value, and solve corresponding feature vector. Compare component vector size that can solve ranking. Finally use analytic hierarchy process, take average score, number of goal difference and ratio between winning games numbers and participation games numbers as criterion layer influence factors, according to their proportional relationships, construct positive reciprocal matrix (inverse matrix), by solving maximum feature value and its feature vector, and then solve ranking. © Trade Science Inc.


Wu H.,Northeast Normal University
BioTechnology: An Indian Journal | Year: 2014

According to object movements corresponding physical laws, using rigid body rotational and translational principles, through establishing mechanical model, it carries out detailed research on cue ball each kind of movement statuses when cue stroking cue ball from different parts, and makes quantitative calculation of cue stroking billiards different heights influence on cue ball movement states, as well as qualitative analyzes cue ball movement statuses after it colliding with object ball. So that it plays certain technical guiding roles in athletes' billiards technique improvement. © 2014 Trade Science Inc. - INDIA.


Zou X.,Harbin Institute of Technology | Wang K.,Harbin Institute of Technology | Wang K.,Northeast Normal University
Nonlinear Analysis: Real World Applications | Year: 2011

Many species are endangered, if we do not act fast, we are going to lose them forever. Establishing protection zone is widely used to protect endangered species. How is the effect of this method? What factors affect the effect of the protection zone? We study this topic by a new mathematical model. We examine the effect of the protection zone and conclude that the protection zone is effective for conservation of population resources and ecological environment, though in some cases the extinction cannot be eliminated. The dangerous region, the parameters domains and the typical bifurcation curves of stability of steady states for the considered system are determined. Our results provide theoretical evidence for the practical management of biological resources. © 2010 Elsevier Ltd. All rights reserved.


Su S.-L.,Harbin Institute of Technology | Shao X.-Q.,Northeast Normal University | Wang H.-F.,Yanbian University | Zhang S.,Harbin Institute of Technology | Zhang S.,Yanbian University
Physical Review A - Atomic, Molecular, and Optical Physics | Year: 2014

We propose a dissipative scheme to generate a maximally entangled state for two Λ-type atoms trapped in an optical cavity. Different from the unitary-dynamics-based scheme, our work shows that both atomic spontaneous emission and cavity decay are no longer detrimental, but necessary for entanglement generation. The scheme is independent of initial states and does not require precise time control. A final numerical simulation with two groups of experimental parameters indicates that the present scheme is feasible and the performance could be better than the unitary-dynamics-based scheme. © 2014 American Physical Society.


Wang S.,Northeast Normal University | Wang S.,University of British Columbia | Li E.,University of British Columbia | Porth I.,University of British Columbia | And 4 more authors.
Scientific Reports | Year: 2014

Poplar has 192 annotated R2R3 MYB genes, of which only three have been shown to play a role in the regulation of secondary cell wall formation. Here we report the characterization of PtrMYB152, a poplar homolog of the Arabidopsis R2R3 MYB transcription factor AtMYB43, in the regulation of secondary cell wall biosynthesis. The expression of PtrMYB152 in secondary xylem is about 18 times of that in phloem. When expressed in Arabidopsis under the control of either 35S or PtrCesA8 promoters, PtrMYB152 increased secondary cell wall thickness, which is likely caused by increased lignification. Accordingly, elevated expression of genes encoding sets of enzymes in secondary wall biosynthesis were observed in transgenic plants expressing PtrMYB152. Arabidopsis protoplast transfection assays suggested that PtrMYB152 functions as a transcriptional activator. Taken together, our results suggest that PtrMYB152 may be part of a regulatory network activating expression of discrete sets of secondary cell wall biosynthesis genes.


Ba X.,University of Texas Medical Branch | Ba X.,Northeast Normal University | Garg N.J.,University of Texas Medical Branch
American Journal of Pathology | Year: 2011

Poly(ADP-ribosyl)ation, attaching the ADP-ribose polymer chain to the receptor protein, is a unique posttranslational modification. Poly(ADP-ribose) polymerase-1 (PARP-1) is a well-characterized member of the PARP family. In this review, we provide a general update on molecular structure and structure-based activity of this enzyme. However, we mainly focus on the roles of PARP-1 in inflammatory diseases. Specifically, we discuss the signaling pathway context that PARP-1 is involved in to regulate the pathogenesis of inflammation. PARP-1 facilitates diverse inflammatory responses by promoting inflammation-relevant gene expression, such as cytokines, oxidation-reduction - related enzymes, and adhesion molecules. Excessive activation of PARP-1 induces mitochondria- associated cell death in injured tissues and constitutes another mechanism for exacerbating inflammation. Copyright © 2011 American Society for Investigative Pathology. Published by Elsevier Inc. All rights reserved.


Deng M.,Cornell University | Deng M.,Northeast Normal University | Wu J.,Cornell University | Reinhart-King C.A.,Cornell University | Chu C.-C.,Cornell University
Acta Biomaterialia | Year: 2011

The synthesis of a new family of biodegradable α-amino acid poly(ester amide)s (AA-PEAs) with pendant benzyl ether groups and hydroxyl functional groups is reported. The synthetic strategy employs the ring opening reaction of O-benzyl-l-serine-N-carboxyanhydride with di-p-toluenesulfonic acid salts of bis-l-valine butane-1,4-diester, followed by solution polycondesation reactions with di-p-nitrophenyl sebacate in N,N-dimethylacetamide. Catalytic hydrogenation of the resulting benzyl ether protected AA-PEAs (PEA-Ser-Bzs) was performed to restore the hydroxyl functional groups in the functionalized AA-PEAs (PEA-Ser-OH). All resulting polymers were characterized by standard physico-chemical methods. The pendant hydroxyl groups in PEA-Ser-OH were used to fabricate AA-PEA-based gels via acrylation and photo-gelation. The cell-polymer interactions of PEA-Ser-Bz and PEA-Ser-OH were evaluated in terms of cell attachment and proliferation assay using bovine aortic endothelial cells (BAECs) as well as fibroblasts. The cell culture data indicated that the hydrophobic/hydrophilic characteristics (from contact angle data) of these AA-PEAs could significantly affect the interaction between BAECs and AA-PEA. This finding may provide additional possible applications for this new family of functionalized AA-PEA polymers. © 2010 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.


BACKGROUND: It is widely recognized that interspecific hybridization may induce "genome shock", and lead to genetic and epigenetic instabilities in the resultant hybrids and/or backcrossed introgressants. A prominent component involved in the genome shock is reactivation of cryptic transposable elements (TEs) in the hybrid genome, which is often associated with alteration in the elements' epigenetic modifications like cytosine DNA methylation. We have previously reported that introgressants derived from hybridization between Oryza sativa (rice) and Zizania latifolia manifested substantial methylation re-patterning and rampant mobilization of two TEs, a copia retrotransposon Tos17 and a MITE mPing. It was not known however whether other types of TEs had also been transpositionally reactivated in these introgressants, their relevance to alteration in cytosine methylation, and their impact on expression of adjacent cellular genes. RESULTS: We document in this study that the Dart TE family was transpositionally reactivated followed by stabilization in all three studied introgressants (RZ1, RZ2 and RZ35) derived from introgressive hybridization between rice (cv. Matsumae) and Z. latifolia, while the TEs remained quiescent in the recipient rice genome. Transposon-display (TD) and sequencing verified the element's mobility and mapped the excisions and re-insertions to the rice chromosomes. Methylation-sensitive Southern blotting showed that the Dart TEs were heavily methylated along their entire length, and moderate alteration in cytosine methylation patterns occurred in the introgressants relative to their rice parental line. Real-time qRT-PCR quantification on the relative transcript abundance of six single-copy genes flanking the newly excised or inserted Dart-related TE copies indicated that whereas marked difference in the expression of all four genes in both tissues (leaf and root) were detected between the introgressants and their rice parental line under both normal and various stress conditions, the difference showed little association with the presence or absence of the newly mobilized Dart-related TEs. CONCLUSION: Introgressive hybridization has induced transpositional reactivation of the otherwise immobile Dart-related TEs in the parental rice line (cv. Matsumae), which was accompanied with a moderate alteration in the element's cytosine methylation. Significant difference in expression of the Dart-adjacent genes occurred between the introgressants and their rice parental line under both normal and various abiotic stress conditions, but the alteration in gene expression was not coupled with the TEs.


Shen H.Z.,Dalian University of Technology | Qin M.,Dalian University of Technology | Xiu X.-M.,Dalian University of Technology | Xiu X.-M.,Bohai University | Yi X.X.,Northeast Normal University
Physical Review A - Atomic, Molecular, and Optical Physics | Year: 2014

The driven two-level system is a useful model to describe many quantum objects, particularly in quantum information processing. However, the exact master equation for such a system has barely been explored. Making use of the Feynman-Vernon influence functional theory, we derive an exact non-Markovian master equation for the driven two-level system and show the lost feature in the perturbative treatment for this system. The perturbative treatment leads to the time-convolutionless (TCL) and Nakajima-Zwanzig (NZ) master equations. So to this end we derive the TCL and NZ master equations for the system and compare the dynamics given by the three master equations. We find the validity condition for the TCL and NZ master equations. Based on the exact non-Markovian master equation, we analyze the regime of validity for the secular approximation in the time-convolutionless master equation and discuss the leading corrections of the nonsecular terms to the quantum dynamics. Significant effects are found in the dynamics of the driven system. © 2014 American Physical Society.


Shen H.Z.,Dalian University of Technology | Zhou Y.H.,Dalian University of Technology | Yi X.X.,Northeast Normal University
Physical Review A - Atomic, Molecular, and Optical Physics | Year: 2014

The semiconductor diode, which acts as an electrical rectifier and allows unidirectional electronic transports, is the key to information processing in integrated circuits. Analogously, an optical rectifier (or diode) working at specific target wavelengths has recently become a highly sought-after device in optical communication and signal processing. In this paper, we propose a scheme to realize an optical diode for photonic transport at the level of few photons. The system consists of two spatially overlapping single-mode semiconductor microcavities coupled via χ(2) nonlinearities. The photon blockade is predicted to take place in this system. These photon blockade effects can be achieved by tuning the frequency of the input laser field (driving field). Based on those blockades, we analytically derive the one- and two-photon current in terms of a zero and a finite time-delayed two-order correlation function. The results suggest that the system can serve as a one- and two-photon quantum optical diode which allows transmission of photons in one direction much more efficiently than in the other. © 2014 American Physical Society.


Li W.,Harbin Institute of Technology | Song H.,Harbin Institute of Technology | Qu Y.,Harbin Institute of Technology | Wang K.,Harbin Institute of Technology | Wang K.,Northeast Normal University
Systems and Control Letters | Year: 2013

This paper investigates the global exponential stability of stochastic coupled systems on networks with Markovian switching (SCSNMS). Sufficient conditions are established to guarantee pth moment exponential stability and almost surely exponential stability of the SCSNMS, by using concepts from graph theory and M-matrix into Lyapunov method. Consequently, the upper boundaries of the pth moment Lyapunov exponent and the sample Lyapunov exponent are given. Finally, to illustrate the capabilities of the stability principle, easy-verifiable sufficient conditions of global exponential stability for a stochastic coupled oscillator on network with Markovian switching are obtained. © 2013 Elsevier B.V. All rights reserved.


Lan Y.-Q.,Japan National Institute of Advanced Industrial Science and Technology | Jiang H.-L.,Japan National Institute of Advanced Industrial Science and Technology | Li S.-L.,Northeast Normal University | Xu Q.,Japan National Institute of Advanced Industrial Science and Technology
Advanced Materials | Year: 2011

Three mesoporous metal-organic frameworks (MOFs) with rare corundum-type topology and size-tailored cages are constructed by length-extendable tetratopic ligands. All the MOFs show selective CO 2 uptake over N 2 and their CO 2 uptake capabilities are discriminated with different cage sizes. The MOFs can serve as hosts for encapsulating extra-framework lanthanide cations, and be applicable in column-chromatographic separation for large dye molecules. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


Li W.,Harbin Institute of Technology | Su H.,Harbin Institute of Technology | Wang K.,Harbin Institute of Technology | Wang K.,Northeast Normal University
Automatica | Year: 2011

This paper considers the global stability problem for some stochastic coupled systems on networks (SCSNs). We provide a systematic method for constructing a global Lyapunov function for these SCSNs, by using graph theory and the Lyapunov second method. Consequently, a new global stability principle, which has a close relation to the topology property of the network, is given. As an application to the results, we employ the principle to two well-known coupled systems in physical and ecology, and then some easy-verified sufficient conditions which guarantee the global stability are obtained. © 2010 Elsevier Ltd. All rights reserved.