North Maharashtra University
Jalgaon, India

North Maharashtra University was established on August 15, 1990 after separating it from the parent University of Pune.The university campus is located at Jalgaon in Maharashtra, India. It occupies an area of 404 acres on the banks of Girna river. Massive plantation has been undertaken to enrich the natural beauty of the campus. In 2001, NAAC Accredited the prestigious 4 Star Status to the University. The university was reaccredited by NAAC as 'B' grade university.Separate hostel facilities for male and female students are available on the campus on the basis of merit and certain other restrictions. Staff quarters are located within the campus.The university library has six floors and more than 50,000 books. There are more than 500 magazines subscribed in the Library reading section.Research students of the North Maharashtra University establish the North Maharashtra University Research Scholar Association on the 14 September 2009 by the hand of Honorable Prin. Dr. K. B. Patil .Currently there are 62 members comprising the university's teaching faculty. Wikipedia.

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Baviskar P.K.,North Maharashtra University
Journal of Solid State Electrochemistry | Year: 2017

Here, we report the deposition of CuSCN as a p-type hole transport material (HTM) using simple and inexpensive chemical route viz. successive ionic layer adsorption and reaction (SILAR) technique over ruthenium metal-free Eosin-Y dye-sensitized zinc oxide (ZnO) nanorod film prepared by chemical bath deposition method at a low temperature. It is shown that the methods used for the deposition are cost effective, post annealing of ZnO at relatively low temperature (200 °C), dye used as an active layer is inexpensive and the SILAR deposited CuSCN thin film was used as it is without any subsequent annealing towards the preparation of solid-state dye-sensitized solar cell (SS-DSSC), which plays a vital role towards the reduction of device fabrication cost. The prepared structure was characterized for structural, optical, morphological and compositional studies. Finally, the device was characterized for photovoltaic measurements under dark and illumination of simulated sunlight at standard AM 1.5G condition (1 sun, 100 mW/cm2). The SS-DSSC fabricated at low temperature was found to yield 0.072% efficiency made with CuSCN as HTM and Eosin-Y as sensitizer. © 2017 Springer-Verlag Berlin Heidelberg

Badgujar S.B.,National Health Research Institute | Badgujar S.B.,North Maharashtra University
Journal of Ethnopharmacology | Year: 2014

Ethnopharmacological relevance Latices from several plant species of Euphorbiaceae family have been traditionally applied over fresh cuts to stop bleeding and subsequently applied over wounds to enhance healing process. The latex arrested bleeding from fresh wounds by reducing bleeding and whole blood coagulation time which are important indices of hemostatic activity. It has been accepted that hemostatic activity is due to the proteolytic fraction of plant latices. Thus, the present study aimed to assess the clot inducing properties of three Euphorbiaceae plants viz., Euphorbia nivulia Buch.-Ham., Pedilanthus tithymaloides (L.) Poit and Synadenium grantii Hook F. Materials and methods In the present study, various proteolytic activities namely protease, gelatinase, milk clotting and whole blood clotting assay of the enzyme fraction of latices of Euphorbia nivulia, Pedilanthus tithymaloides and Synadenium grantii have been investigated. The inhibition profile of protease specific inhibitors was assessed. Also, the effects of protein fractions were studied using bleeding/clotting time test of fresh experimentally-induced wounds in mice. Results Euphorbia nivulia latex protease has noticeable blood clotting activity followed by Pedilanthus tithymaloides and Synadenium grantii. Stem latex protease of Pedilanthus tithymaloides exhibits superior procoagulant activity in different mammal's blood samples viz., Capra hircus, Bubalus bubalis, Ovibos moschatus and Bos indicus. Blood sample of ox was the most sensitive to latex protease than other mammal's blood. Concomitantly, the plant latex protease could significantly reduce whole blood clotting time of human and mice blood samples. Conclusion The protease fraction of latices of Euphorbia nivulia, Pedilanthus tithymaloides and Synadenium grantii possesses phytoconstituents capable of arresting wound bleeding, and accelerating whole blood coagulation process. It suggests good potentiality for use of latex proteases in wound management. Also, the finding of this study showed that the protease enzyme of Pedilanthus tithymaloides has the most potent hemostatic agent. © 2013 Elsevier Ireland Ltd.

Gore R.P.,North Maharashtra University | Rajput A.P.,Zb Patil College
Drug Invention Today | Year: 2013

The multicomponent reactions (MCRs) are emerging as environmental benign synthetic methods of building-up of complex molecules with maximum complexity and several level of structural diversity for diverse applications. This review article provides an overview of recent progress in MCRs of synthesis of pyrimidine derivatives covering only recent literature. © 2013 .

Deshmukh R.K.,North Maharashtra University | Naik J.B.,North Maharashtra University
Journal of Pharmaceutical Innovation | Year: 2013

Purpose: In this study, polymeric microspheres containing diclofenac sodium were prepared by single emulsion (oil-in-water) solvent evaporation method and evaluated for their size, morphology, encapsulation efficiency, drug loading, and in vitro drug release. Methods: Two nonbiodegradable polymers, Eudragit® RS100 and RL100 were used in combination. Microspheres were prepared by varying the amount of polyvinyl alcohol as a surfactant (0.05, 0.125, and 2.0%, w /v ) to the external phase; varying the amount of polymer (1:1, 2:1, and 3:1, w /w ) to the drug by employing 32 full factorial design using the Design Expert (Version The drug polymer interactions were investigated by Fourier transform infrared spectroscopy (FTIR) and X-ray powder diffractometry (XRPD). Imaging of particles was performed by field emission scanning electron microscopy. Results: Graphical and mathematical analysis of the design showed a quadratic model was significant for the responses. Low magnitude of error and significant values of R2 proves the high prognostic ability of the RSM. Encapsulation efficiency of microspheres (41.13 to 65.33%) increases with an increase in surfactant concentration but decreases with an increase in polymer concentration. Themicrospheres were found to be discrete, spherical with smooth surface. The absence of drug polymer interactions was confirmed by FTIR spectroscopy. XRPD revealed the dispersion of drug within microspheres formulation. The Perfect pH-independent release profile was achieved from Eudragit® microspheres by anomalous transport mechanism. Conclusions In conclusion, Eudragit® microspheres containing diclofenac sodium can be successfully prepared, and seem to be promising for sustained release application. © Springer Science+Business Media 2013.

Shinde V.P.,North Maharashtra University
Ionics | Year: 2017

Poly(o-ethylaniline) (POEA) coatings were synthesized on copper from aqueous solution containing o-ethylaniline and sodium salicylate by using cyclic voltammetry. This coating was characterized by mass spectroscopy. The corrosion protection behaviors of these coatings were evaluated by electrochemical impedance spectroscopy (EIS) in aqueous NaCl solution. Diffusion coefficient of water and chloride ion in POEA coatings on copper were investigated by EIS parameters. Due to these diffusion process variations in various properties of coatings such as dielectric constant, resistivity and diffusion layer thickness has been observed. All these parameters are useful for explaining corrosion mechanism of POEA coating in NaCl solution. © 2017 Springer-Verlag GmbH Germany

Patil K.S.,North Maharashtra University | Bhalsing S.R.,North Maharashtra University
Journal of Ethnopharmacology | Year: 2016

Ethnopharmacological relevance The genus Boerhavia is widely distributed in tropical, subtropical and temperate regions of the world including Mexico, America, Africa, Asia, Indian Ocean Islands, Pacific Islands and Australia. The genus Boerhavia is extensively used by local peoples and medicinal practitioners for treatments of hepatitis, urinary disorders, gastro intestinal diseases, inflammations, skin problems, infectious diseases and asthma. Present review focused on traditional uses, phytochemistry, pharmacology and toxicology of Boerhavia genus to support potential scope for advance ethnopharmacological study. Materials and methods Information on the Boerhavia species was collected from classical books on medicinal plants, pharmacopoeias and scientific databases like PubMed, Scopus, GoogleScholar, Web of Science and others. Also scientific literatures based on ethnomedicinal surveys, Ph.D. and M.Sc. dissertations, published papers from Elsevier, Taylor and Francis, Springer, ACS as well as Wiley publishers and reports by government bodies and documentations were assessed. Results A total of 180 compounds from Boerhavia genus were isolated of which B. diffusa alone shared around 131 compounds and for most of which it is currently an exclusive source. In the genus, phenolic glycosides and flavonoids contribute approximately 97 compounds. These includes eupalitin, rotenoids like boeravinones, coccineons, alkaloid i.e. betanin and punarnavine etc., showing vital pharmaceutical activities such as anticancer, anti-inflammatory, antioxidant and immunomodulatory. Conclusion Boerhavia is an important genus with wide range of medicinal uses. However, most of the available scientific literatures have lacked relevant doses, duration and positive controls for examining bioefficacy of extracts and its active compounds. In some studies, taxonomic errors were encountered. Moreover, there is need for accurate methods in testing the safety and ethnomedicinal validity of Boerhavia species. © 2016 Published by Elsevier Ireland Ltd.

Chaudhari S.,North Maharashtra University | Patil P.P.,North Maharashtra University
Electrochimica Acta | Year: 2011

Polyaniline (PANI) coatings were electrochemically synthesized on nickel (Ni) coated mild steel (MS) and their corrosion protection properties were investigated. In this work, the Ni layer (∼1 μm thick) was electrodeposited on MS under galvanostatic condition. Thereafter, the PANI coating was deposited over the Ni layer from aqueous salicylate medium by using cyclic voltammetry. These bi-layered composite coatings were characterized by cyclic voltammetry, UV-vis absorption spectroscopy and Fourier transform infrared (FTIR) spectroscopy. The corrosion protection properties of Ni coated MS (Ni/MS) and PANI coated Ni/MS (PANI/Ni/MS) were investigated in aqueous 3% NaCl by using open circuit potential (OCP) measurements, potentiodynamic polarization technique and electrochemical impedance spectroscopy (EIS). It was shown that the top layer of PANI exhibits a lower porosity behavior with respect to Ni coating and reduces the corrosion rate of Ni/MS almost by a factor of 3500 and increases the lifetime of Ni coating. © 2011 Elsevier Ltd. All rights reserved.

Shinde V.P.,North Maharashtra University | Patil P.P.,North Maharashtra University
Electrochimica Acta | Year: 2012

Electrochemical polymerization of the aniline, o-anisidine and o-toluidine coatings on low carbon steel has been carried out under galvanostatic conditions in an aqueous oxalic acid solution. The E-t curves show three distinct stages - dissolution of the low carbon steel surface and formation of polycrystalline iron oxalate interphase, complete passivation of low carbon steel surface and the electrochemical polymerization of respective monomer(s). To understand the role of monomer(s) during the electrochemical polymerization process, the passive interphase samples were characterized by X-ray photoelectron spectroscopy. The results of this study show that monomer(s) are taking a part in first stage of electrochemical polymerization and passivation time depends on the type of monomer(s) present in electrolyte. © 2012 Elsevier Ltd.

Bhalerao T.S.,North Maharashtra University
Turkish Journal of Biology | Year: 2012

The persistence of endosulfan and intermediate metabolite endosulfan sulfate in the environment and their toxic effects on biota necessitate their removal. This study investigated the bioaugmentation of endosulfan-contaminated soil by fungal inoculant Aspergillus niger ARIFCC 1053. The influence of bioaugmentation by A. niger on endosulfan-contaminated soil was evaluated with the help of change in pH and released chloride, and by thin layer chromatography and gas chromatography analysis. Its effects on soil functionality were monitored by estimating dehydrogenase and arylsulfatase enzyme activities. The endosulfan degradation reached an undetectable level on day 15. The pH of the medium was nearly neutral (6.9) at the time of inoculation and it decreased to 3.6 on day 15. The amount of chloride released at particular intervals in the endosulfan degradation ranged from 28 mg mL-1 to 104 mg mL-1. Change in pH and the increase in released chloride correlated with metabolic activities involved in the simultaneous degradation of endosulfan. Endosulfan sulfate, an intermediate metabolite, was detected and had disappeared on day 11 of the process. The increase in enzyme activities is an indicator of soil fertility and suggests possible involvement of these enzymes in endosulfan degradation. These results demonstrate that bioaugmentation by A. niger may be a viable tool for the remediation of soil contaminated with endosulfan. © TÜBITAK.

Thakur S.,North Maharashtra University | Patil P.,North Maharashtra University
Sensors and Actuators, B: Chemical | Year: 2014

This paper reports a simple and rapid microwave-assisted method for synthesizing cerium oxide (CeO2) nanoparticles for the fabrication of high-performance humidity sensors. The humidity-sensing investigation reveals that the sensor based on CeO2 nanoparticles exhibits a high and linear response within the entire relative humidity (RH) range of 11-97% at an operating frequency of 60 Hz. The corresponding impedance changes by approximately three orders of magnitude within the entire humidity range from 11% to 97%. The response and recovery times are approximately 3 and 16 s, respectively. Additionally, the sensor exhibits a rapid and reversible response characterized by a very small hysteresis (∼1%RH), excellent repeatability, long term stability and a broad range of operation (11-97%RH). The Nyquist impedance plots of the sensor at different RHs were used to elucidate the sensor's humidity-sensing mechanism via an electrical equivalent circuit. The experimental results provide a possible method for the rapid synthesis and fabrication of high-performance humidity sensors based on CeO2 nanoparticles. © 2013 Elsevier B.V.

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