Nordsjaellands Hospital

Hillerød, Denmark

Nordsjaellands Hospital

Hillerød, Denmark
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We present a case of total anomalous pulmonary venous drainage. Despite low oxygen saturation an eight-week-old girl had only minimal symptoms initially. She suffered collapse requiring acute surgical correction and prolonged intensive care. Her collapse and complicated post-operative course could have been avoided with earlier diagnosis. Infants with critical heart disease continue to be born undiagnosed despite prenatal ultrasound screening. There is evidence that infants with critical congenital heart defect can be detected by pulse oximetry screening, as is routine in Norway, Sweden and Finland, but not in Denmark.


We describe a rare case of bilateral tubal pregnancy following natural conception in a woman with no other known risk factor than two former caesarean sections. Intraabdominal adhesions following the caesarean sections complicated the salpingectomy thus diminishing certainty of a healthy contralateral tube. The woman was readmitted three weeks later and had an additional salpingectomy on behalf of an unrecognized tubal pregnancy. Considering the rising caesarean section rates clinicians need to be certain of no additional ectopic pregnancy while performing the primary operation.


Varices of the terminal ileum are not a common complication to portal hypertension but we describe a case where a 60-year-old male patient had massive, recurrent intestinal bleeding due to collateral blood supply from umbilical veins to varicose veins of the terminal ileum.


Volar dislocation of the second and third carpometacarpal joint is extremely rare and most often caused by high-energy trauma. In this case a 15-year-old boy fell on his hand while playing soccer. The injury was undiagnosed for three months, perhaps due to an ipsilateral forearm fracture. He was treated with open reduction and Kirchner wire fixation for nine weeks. At two years follow-up he had a painfree hand with a 20% reduction in grip strength.


Uldum S.A.,Statens Serum Institute | Bangsborg J.M.,Herlev University Hospital | Gahrn-Hansen B.,University of Southern Denmark | Ljung R.,Nordsjaellands Hospital | And 3 more authors.
Eurosurveillance | Year: 2012

Denmark experienced two waves of Mycoplasma pneumoniae infection during autumn and early winter in 2010 and 2011, respectively. Both affected the whole country. The proportion of positive results was almost the same for both, indicating that the two waves were probably of equal size. High macrolide consumption during the epidemics did not seem to affect levels of macrolide resistance in M. pneumoniae, which remain low in Demark (1% to 3%).


Halladin N.L.,Herlev Hospital | Zahle F.V.,Nordsjaellands Hospital | Rosenberg J.,Herlev Hospital | Gogenur I.,Herlev Hospital
Anaesthesia | Year: 2014

Ischaemia of the extremity from the use of a tourniquet and the subsequent reperfusion contribute to the release of reactive oxygen species. This release may result in injury to remote organs. We performed a qualitative systematic review exploring the interventions used to prevent tourniquet-related oxidative damage in adults undergoing orthopaedic surgery, and the possible relationship between biochemical oxidative stress markers and postoperative clinical outcomes. Seventeen randomised controlled studies were included in the qualitative synthesis. Most trials were of low methodological quality and only two studies reported postoperative clinical outcomes. Nine studies tested anaesthetics (propofol, dexmedetomidine, ketamine, and spinal anaesthesia); four studies tested antioxidants (N-acetyl-cysteine, vitamin C, and mannitol); and four studies tested ischaemic pre-conditioning. Fifteen studies showed a significant reduction in biochemical oxidative stress markers. We conclude that propofol and ischaemic pre-conditioning, in particular, appear to show some benefit at reducing oxidative stress following operations under tourniquet; the correlation between a reduction in oxidative stress and postoperative clinical outcomes should be further investigated in the future. © 2014 The Association of Anaesthetists of Great Britain and Ireland.


Nilsson C.,Nordsjaellands Hospital | Sorensen B.L.,Copenhagen University | Sorensen J.L.,Copenhagen University
Acta Obstetricia et Gynecologica Scandinavica | Year: 2014

The objective was to compare two teaching methods for postpartum hemorrhage management: interactive hands-on training and non-interactive video training. In a controlled intervention study at a secondary health care center in Kenya, the two training methods, based on the Advanced Life Support in Obstetrics curriculum, were evaluated utilizing structured observation of a standardized scenario before and after training. Both intervention groups significantly increased in performance scores after receiving hands-on training: 40% (95% CI 29.5-47.0) and video training: 34.5% (95% CI 25.0-42.0); likewise, pass rates improved significantly. No significant differences in performance score or pass rates were found between the two methods. The findings indicate that postpartum hemorrhage management training by mobile media might be just as effective as conventional hands-on training and a feasible way to overcome the outreach gap in sub-Saharan Africa's rural areas, where peripheral health facilities are generally difficult to reach with conventional training programs. © 2014 Nordic Federation of Societies of Obstetrics and Gynecology.


Sejling A.-S.,Nordsjaellands Hospital | Sejling A.-S.,University of Southern Denmark | Thorsteinsson A.-L.,Nordsjaellands Hospital | Pedersen-Bjergaard U.,Nordsjaellands Hospital | And 3 more authors.
Journal of Clinical Endocrinology and Metabolism | Year: 2014

Conclusion: This case provides evidence for a causal relationship between SIADH and chronic hyponatremia and impaired bone metabolism that can lead to severe secondary osteoporosis. The effect on bone metabolism is at least partially reversible.The Case: A 38-year-old man had been diagnosed with severe osteoporosis most likely due to chronic SIADH. The SIADH was believed to be idiopathic. A magnetic resonance imaging scan, however, revealed a tumor in the sinus, and biopsies showed an esthesioneuroblastoma, immunohistochemically positive for antidiuretic hormone (ADH). After the tumor was removed, ADH and sodium levels normalized. Adual-energy x-ray absorptiometry scan performed 7months after the patient's last surgery showed a significant spontaneous improvement in bone mineral density in the lumbar vertebrae.Introduction: Recent studies show an association between hyponatremia and osteoporosis. We have previously reported a case of severe male osteoporosis due to chronic syndrome of inappropriate secretion of antidiuretic hormone (SIADH). Here, we provide a follow-up on this case after cure of the condition that further supports the causal relationship. Copyright © 2014 by the Endocrine Society.


Sorup C.M.,Technical University of Denmark | Jacobsen P.,Technical University of Denmark | Forberg J.L.,Nordsjaellands Hospital
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine | Year: 2013

Background: Evaluation of emergency department (ED) performance remains a difficult task due to the lack of consensus on performance measures that reflects high quality, efficiency, and sustainability.Aim: To describe, map, and critically evaluate which performance measures that the published literature regard as being most relevant in assessing overall ED performance.Methods: Following the PRISMA guidelines, a systematic literature review of review articles reporting accentuated ED performance measures was conducted in the databases of PubMed, Cochrane Library, and Web of Science. Study eligibility criteria includes: 1) the main purpose was to discuss, analyse, or promote performance measures best reflecting ED performance, 2) the article was a review article, and 3) the article reported macro-level performance measures, thus reflecting an overall departmental performance level.Results: A number of articles addresses this study's objective (n = 14 of 46 unique hits). Time intervals and patient-related measures were dominant in the identified performance measures in review articles from US, UK, Sweden and Canada. Length of stay (LOS), time between patient arrival to initial clinical assessment, and time between patient arrivals to admission were highlighted by the majority of articles. Concurrently, " patients left without being seen" (LWBS), unplanned re-attendance within a maximum of 72 hours, mortality/morbidity, and number of unintended incidents were the most highlighted performance measures that related directly to the patient. Performance measures related to employees were only stated in two of the 14 included articles.Conclusions: A total of 55 ED performance measures were identified. ED time intervals were the most recommended performance measures followed by patient centeredness and safety performance measures. ED employee related performance measures were rarely mentioned in the investigated literature. The study's results allow for advancement towards improved performance measurement and standardised assessment across EDs. © 2013 Sørup et al.; licensee BioMed Central Ltd.


We present two cases in which the patients were admitted to a local hospital with acute abdominal pain four or five months after having undergone laparoscopic gastric bypass. In both cases, operation revealed a perforation of the small bowel close to the distal anastomosis. In the first case, a massive constipation of the small bowel was most likely a contributing factor. In the second case, the cause was a kink of the entero-entero anastomosis leading to obstruction and finally perforation of the biliary limp. Late perforations are among the rarely reported complications associated with gastric bypass but as our two cases illustrate they are important to keep in mind.

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