News Article | May 4, 2017
DUBLIN--(BUSINESS WIRE)--Research and Markets has announced the addition of the "Bone Densitometers Market, 2014-2025" report to their offering. The global bone densitometers market is expected to reach USD 1.2 billion by 2025. The growing prevalence of metabolic bone diseases is believed to be responsible for the high clinical urgency to adopt bone densitometers, thereby impelling the market demand. Growing base of geriatric and obese population, which is highly susceptible to developing disorders such as osteoporosis, is anticipated to propel the demand further. The aforementioned factors are slated to present the market with lucrative growth opportunities over the coming years. Moreover, presence of consistent number of health initiatives to promote awareness pertaining to osteoporosis is anticipated to broaden market growth potential over the coming years. For instance, National Osteoporosis Foundation (NOF), a government healthcare organization that conducts National Bone Health Alliance and Fracture Liaison Service (FLS) care coordination programs, is focused on elevating awareness levels pertaining to available diagnostic & treatment alternatives for osteoporosis. It also encourages training of healthcare professionals for efficient management of osteoporosis. In addition, advent of technologically advanced devices, such as portable densitometers, is presumed to fuel their adoption in home healthcare. Other technological advancements include implementation of advanced hip assessment software into DXA systems that enabled noninvasive assessment of proximal femur structural geometry. Additional associated benefits include depiction of wide array of parameters such as skeletal mapping, hip axis length assessment, areal BMD determination, and cross-sectional area & the femoral strength index. For more information about this report visit http://www.researchandmarkets.com/research/7szhvr/bone
News Article | April 24, 2017
The global osteoporosis drugs market is expected to reach USD 16.3 billion by 2025 An upsurge rise in the unhealthy lifestyle adoption has resulted in aggravation and increase in the prevalence of osteoporosis which is presumed to propel the osteoporosis drugs market during the forecast period. In addition, growing number of patent expiries is fueling the high clinical urgency to use generic versions of the established drugs, which is presumed to fuel generic osteoporosis drugs market during the forecast period. The aforementioned factors cumulatively are slated to present the with high potential growth opportunities over the coming years. Furthermore, rising number of initiatives to increase the awareness levels pertaining to osteoporosis care amongst the patients as well as the physicians is expected to widen the osteoporosis market growth potential during the forecast period. For instance, National Osteoporosis Foundation (NOF), a healthcare organization responsible for National Bone Health Alliance and Fracture Liaison Service (FLS) care coordination programs that focuses on elevating awareness levels as well as provides training to healthcare professionals Further key findings from the study suggest: For more information about this report visit http://www.researchandmarkets.com/research/dlf8sz/osteoporosis To view the original version on PR Newswire, visit:http://www.prnewswire.com/news-releases/global-osteoporosis-drugs-market-analysis-2014-2017--2025-market-is-expected-to-reach-usd-163-billion---research-and-markets-300444093.html
News Article | May 1, 2017
To prevent osteoporosis, you must build the strongest and densest bone you can early in life. You develop what is known as "peak bone mass" between the ages of 25-30, after that you break down bone at a faster rate than you build it. It's important to consume a healthy diet, including adequate calcium and vitamin D, and do weight-bearing and muscle-strengthening exercises to build peak bone mass and to maintain your bone strength throughout your lifetime. "We know osteoporosis causes two million broken bones every year in the U.S., yet the majority of Americans don't realize how important their bone health is until they have a debilitating fracture," said Amy Porter, executive director and CEO, National Osteoporosis Foundation. "That's why we're encouraging everyone to Break Free from Osteoporosis and accept our Jumping Jack Challenge to ensure people of ALL ages know how important good bone health really is." Jumping jacks are a recommended activity for building strong bones and helping to achieve Peak Bone Mass early in life. The Jumping Jack Challenge asks you to film yourself or your family or friends doing 10 jumping jacks in less than 10 seconds. Post the video to social media tagging your friends and asking them to take the Jumping Jack Challenge. If they don't accept the challenge, ask that they make a donation to NOF to help raise awareness and support research in bone health. Use the hashtag #JumpingJackChallenge to help spread the word. Throughout the month of May, NOF will provide webinars and resources to healthcare professionals and the public with tips on building and maintaining bone health as well as diagnosing and treating osteoporosis. These free downloadable materials and webinar registration links can be found on the NOF website at www.nof.org. Established in 1984, the National Osteoporosis Foundation is the nation's leading health organization dedicated to preventing osteoporosis and broken bones, promoting strong bones for life and reducing human suffering through programs of awareness, education, advocacy and research. For more information on the National Osteoporosis Foundation, visit www.nof.org. To view the original version on PR Newswire, visit:http://www.prnewswire.com/news-releases/how-strong-are-your-bones-may-is-national-osteoporosis-month-300448615.html
Watanabe Y.,Osaka Municipal Technical Research Institute |
Sato S.,Japan Food Research Laboratories |
Asada M.,Showa Sangyo Co. |
Arishima T.,Fuji Oil Co. |
And 17 more authors.
Journal of Oleo Science | Year: 2015
The positional distributions of fatty acids (FAs) in fats and oils are principally analyzed by selectively transesterifying the target triacylglycerols (TAGs) at the 1(3) position using Pseudozyma (Candida) antarctica lipase, followed by recovering the resulting 2-monoacylglycerols (MAGs) by chromatography. FA compositions were measured by gas chromatography (GC) after methylating target TAGs and 2-MAGs. The method was collaboratively evaluated by 12 laboratories by analyzing the positional FA distributions in soybean, palm, and sardine oils. The maximum reproducibility relative standard deviations for the major FAs and those at the sn-2 positions of soybean, palm, and sardine oils were 4.41% and 3.92% (18:3n-3), 4.48% and 3.82% (18:0), and 8.93 and 8.24% (14:0), respectively. The values at the sn-2 position were always low. Therefore, these results indicated that the variations were mainly caused by the FA analysis procedure, i.e., the methylation and GC analyses, rather than the enzymatic transesterification and chromatography utilized to prepare 2-MAGs from the target oil. © 2015 by Japan Oil Chemists’ Society.
Yoshinaga K.,Tsukishima Foods Industry Co |
Sato S.,Japan Food Research Laboratories |
Sasaki R.,Miyoshi Oil and Fat Co |
Asada M.,Showa Sangyo Co |
And 12 more authors.
Journal of Oleo Science | Year: 2016
The positional distributions of fatty acids (FAs) in milk fat containing short- and medium-chain FAs were analyzed by sn-1(3)-selective transesterification of triacylglycerols (TAGs) with ethanol using immobilized Candida antarctica lipase B (CALB), in a collaborative study conducted by 10 laboratories. The mean C4:0, C6:0, and C8:0 FA contents, when analyzed as propyl esters (PEs) using gas chromatography (GC) with a DB-23 capillary column, were found to be 3.0, 2.0, and, 1.3 area%, respectively. Their reproducibility standard deviations were 0.33, 0.18, and 0.19, respectively. The mean C4:0, C6:0, and C8:0 contents at the sn-2 position were 0.3, 0.4, and 1.0 area%, respectively. Their reproducibility standard deviations were 0.17, 0.11, and 0.19, respectively. The reproducibility standard deviations of C4:0, C6:0, and C8:0 FAs at the sn-2 position were either the same as or smaller than those for milk fat, although the FA contents at the sn-2 position were smaller than those in the milk fat. Therefore, it was concluded that the CALB method for estimating the regiospecific distribution is applicable to TAGs containing short- and medium-chain FAs. When estimating the short-chain (SC) FA contents in fats and oils by GC, it is better to analyze SCFAs as PEs or butyl esters, and not as methyl esters, in order to prevent loss of SCFAs during the experimental procedure because of their volatility and water solubility. This study also revealed that the stationary phase of the GC capillary column affected the flame ionization detector (FID) response of SCFAs. The theoretical FID correction factor (MWFA/active carbon number/atomic weight of carbon) fitted well with the actual FID responses of C4:0-C12:0 FAs when they were analyzed as PEs using a DB-23 column; however, this was not the case when the GC analysis was performed using wax-type columns. © 2016 by Japan Oil Chemists’ Society.
Sakai H.,Tokyo University of Science |
Aikawa S.,Tokyo University of Science |
Matsuda W.,Tokyo University of Science |
Ohmori T.,Shiseido Co. |
And 10 more authors.
Journal of Colloid and Interface Science | Year: 2012
We have developed a novel cinnamic acid-type photo-cleavable surfactant. This surfactant experiences photo-cleavage through UV-induced cyclization in aqueous solutions. The photo-cleavage not only reduces its capabilities as a surfactant but also yields two functional materials including a coumarin derivative and an aminated polyoxyethylene compound. This means that the photo-cleavable surfactant synthesized in this study is a photo-responsive function-exchangeable material. In our current study, we have characterized the photo-cleavable behavior that occurs in aqueous solutions and a resulting change in interfacial properties. The photo-cleavage induces an increased interfacial tension of a squalane/water interface and a decreased solubilization capability of the surfactant micelles. © 2012 Elsevier Inc.
Aikawa S.,Tokyo University of Science |
Shrestha R.G.,Tokyo University of Science |
Ohmori T.,Shiseido Co. |
Fukukita Y.,Shiseido Co. |
And 8 more authors.
Langmuir | Year: 2013
Recently, we have reported a new cinnamic acid-type photocleavable surfactant, C4-C-N-PEG9 that experiences a photocleavage through UV-induced cyclization in aqueous solution, yielding a coumarin derivative (7-butoxy-2H-chromen-2-one) and an aminated polyoxyethylene compound. Here, we have studied the effects of C4-C-N-PEG9 on the photorheological behavior of viscoelastic wormlike micelles formed by aqueous mixture of nonionic surfactants, polyoxyethylene phytosterol ether (PhyEO20) and tetraoxyethylene dodecyl ether (C12EO4). The 4.9 wt % PhyEO20/H2O + 2.4 wt % C12EO4 solution forms wormlike micelles, and its viscosity is ∼10 Pa·s. We have found that the addition of C4-C-N-PEG9 into this viscous, non-Newtonian fluid system decreases the viscosity. Viscosity decreased in parallel to the C4-C-N-PEG9 concentration reaching ∼0.003 Pa·s at 2.5 wt % of C4-C-N-PEG9. However, viscosity of the C4-C-N-PEG9 incorporated system increased significantly (∼200 times at 1.5 wt % of C4-C-N-PEG9 system) upon UV irradiation. Small-Angle X-ray scattering studies have shown that addition of C4-C-N-PEG9 favors wormlike-to-sphere type transition in the micellar structure. However, UV irradiation in the C4-C-N-PEG9 incorporated system causes one-dimensional micellar growth. Since C4-C-N-PEG9 has relatively bigger headgroup size compared to the C12EO4, addition of C4-C-N-PEG9 into wormlike micelles reduces the critical packing parameter resulting in the formation of spherical aggregates. UV irradiation induced one-dimensional micellar growth is caused due to photocleavage of the C4-C-N-PEG9 into a less surface-active coumarin derivative and an aminated polyoxyethylene compound, as confirmed by UV-vis spectrometry and HPLC measurements. The hydrophobic coumarin derivative formed after cleavage of C4-C-N-PEG9 goes to the micellar core and is responsible for decreasing the viscosity. However, the hydrophilic aminated polyoxyethylene prefers to reside at the vicinity of headgroup of PhyEO20 reducing the interhead repulsion, increasing the critical packing parameter and the viscosity as well. © 2013 American Chemical Society.