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Ismail-zade R.S.,Republican Center for Pediatric Oncology and Hematology Research | Zhavrid E.A.,Nnalexandrov Research Institute Of Oncology And Medical Radiology | Aleinikova O.V.,Republican Center for Pediatric Oncology and Hematology Research | Potapnev M.P.,Research Institute of Hematology and Transfusiology | And 4 more authors.
Voprosy Onkologii | Year: 2010

Tentative results of LAK-cell and whole-body hyperthermia (WBH) were evaluated in 19 children with advanced chemorefractory tumors. LAK-cells were obtained by extracorporeal incubation of peripheral blood lymphocytes: a germ-cell rhabdomyosarcoma was detected in 4, Askin's tumor -2 - 2, renal - cell carcinoma - 2 and miscellaneous - 7. Autologous LAK-cells were infused twice: on completion of WBH as body temperature fell to as low as (+) 40 deg. C and on day after WBH. The latter was well tolerated. Complete or partial response to thermochemobiotherapy was reported in 8 patients. Overall 5-year survival was 43% (median follow-up - 12.6 months). Source


Zalutsky I.V.,Nnalexandrov Research Institute Of Oncology And Medical Radiology | Makhnach L.M.,Nnalexandrov Research Institute Of Oncology And Medical Radiology | Zhukovets A.G.,Nnalexandrov Research Institute Of Oncology And Medical Radiology | Shishkovskaya O.A.,Nnalexandrov Research Institute Of Oncology And Medical Radiology
Voprosy Onkologii | Year: 2010

Our paper deals with psychological and psychopathological features of cancer patient personality. Our data deals with on influence of such characteristics on attitudes of cancer patients towards the disease. The impact of pre-morbid features of patients on their attitudes was established. It was shown that maladapted patients with both intra- (neurasthenia, anxiety, hypochondria, ascetism) and inter-psychic (sensitivity) features Our results may contribute to development of efficient methods of copying strategy connection which in turn may alleviate dysadaptation of cancer patients. Source

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