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Sagarad S.V.,NMC and H | Thakur B.S.,NMC and H Raichur | Reddy S.S.,NMC and H | Balasubramanya K.,DCH | And 2 more authors.
Journal of Clinical and Diagnostic Research | Year: 2013

Objective: This study was to evaluate the levels of NT-proBNP in patients with myocarditis which occurred after a scorpion sting envenomation. Material and Methods: A total of 30 patients with scorpion sting envenomation and 21 patients with heart failure which was caused by cardiomyopathy, were prospectively studied. The data included the patient demographics, clinical features, echocardiography and the NT-proBNP levels. Results: An echocardiographic evidence of myocarditis with a left ventricular ejection fraction of less than 50%, was found in 22 patients. In all the 22 patients, NT-proBNP was significantly elevated. The NT-proBNP levels were very high in the patients with severe LV dysfunction. However, it was in the normal range in the patients without an evidence of myocarditis. The elevated NT-proBNP levels were correlated with the LV dysfunction and myocarditis. When they were compared with the patients with heart failure which was caused by cardiomyopathy, the NT-proBNP levels were found to be significantly more elevated in scorpion sting myocarditis. Conclusions: The NT-proBNP levels were significantly elevated in myocarditis which occurred after a scorpion sting envenomation. Source


Sagarad S.V.,NMC and H | Thakur B.S.,NMC and H Raichur | Reddy S.S.,NMC and H | Balasubramanya K.,RGSSH | And 2 more authors.
Journal of Clinical and Diagnostic Research | Year: 2012

Objective: This study was to evaluate the predictive value of the cardiac troponins in scorpion sting myocarditis at a tertiary care hospital in Raichur, (Karnataka state) India. Methods: A total of 84 consecutive patients were prospectively studied. The data included the demographics, the time of presentation to the hospital, the clinical features, the cardiac troponin levels and the echocardiographic findings. Results: 12 patients with only local symptoms had troponin levels of less than 0.01μg/L. 12 patients with local and systemic symptoms without an echocardiac evidence of myocarditis had troponin values of 0.01 to 0.11 μg/L. 60 patients with an echocardiographic evidence of myocarditis had troponin levels of above 0.11 μg/L. 6 patients with severe myocarditis who required ventilator support or which led to death had troponin values which were higher than 10 μg/L. Conclusions: High cardiac troponin levels predict myocarditis in scorpion sting envenomation and they can be a useful tool in guiding the therapy early. Source

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