niv Estadual Paulista

Jaboticabal, Brazil

niv Estadual Paulista

Jaboticabal, Brazil
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Sivieri K.,niv Estadual Paulista | Bassan J.,niv Estadual Paulista | Peixoto G.,niv Estadual Paulista | Monti R.,niv Estadual Paulista
Current Opinion in Food Science | Year: 2017

This mini-review covers the potential interactions between gut microbiota and antimicrobial peptides, as well as the main mechanisms of action of antimicrobial peptides. One of the most efficient molecules produced by resident gut microbiota are peptides, which have antimicrobial functions and an innate immune response against infectious agents. Currently, more than 2300 AMPs have been isolated. The human gut microbiota regulates the production of defensins, cathelicidins, C-type lectins, ribonucleases, and S100 proteins in intestinal epithelial cells and Paneth cells, which rapidly kill or inactivate invading microorganisms. The study of gut microbiota and new peptides provides perspective for the synthesis of analogous molecules as an alternative in solving the problem of multidrug resistance reported with conventional antibiotics. © 2017 Elsevier Ltd

Bonfim G.,niv. Estadual Paulista | Medola F.,niv. Estadual Paulista | Paschoarelli L.,niv. Estadual Paulista
Advances in Intelligent Systems and Computing | Year: 2017

Nine different consumable products were evaluated: two packaging that already existed in the market; and nine prototypes developed as alternatives to those existing packaging. An SD protocol was applied with ten pairs of antagonistic adjectives; and a SUS protocol, with ten sentences for such products. Videos that showed the use process of each package and prototype were recorded. After watching the videos, participants answered the SD and SUS protocols. Results showed that the evaluation technique by SD and SUS, through videos, proved to be relevant. The prototypes that met aesthetic and functional requirements, and sought to minimize ergonomic issues, obtained expressive positive evaluations in both the SD and SUS protocols. © Springer International Publishing Switzerland 2017.

Bonfim G.,niv. Estadual Paulista | Medola F.,niv. Estadual Paulista | Paschoarelli L.,niv. Estadual Paulista
Advances in Intelligent Systems and Computing | Year: 2017

The teaching of ergonomic design of packages requires an experience of prototype development that can be evaluated and compared with similar commercially available products. This study was aimed to report an experience of development and evaluation of consumable product packages in a teaching context of ergonomic design. Videos were recorded to assess the perceived usability of packages and prototypes. It was applied SUS and SD protocols to evaluate the products. The teaching experience in assessing consumer products packaging, the use of assessment parameters in the design of new packages and the development of prototypes that meet aesthetic, functional and especially ergonomic requirements, were expressively positive to the comprehension of the process by the actors (students) involved. © Springer International Publishing Switzerland 2017.

Several composites and nanocomposites based on a polymeric matrix and ceramic fillers are being pursued for use as multifunctional and innovative materials. Nevertheless, there is a series of challenges to be solved in this area such as the understanding of the role of interfaces and the synergy between matrix and fillers. In this work, vulcanized natural rubber nanocomposites were prepared with different concentrations of two kinds of ceramic nanoparticles, potassium strontium niobate (KSr2Nb5O15 or KSN) and nickel–zinc ferrite (Ni0.5Zn0.5Fe2O4 or NZF), synthesized by a chemical method known as the modified polyol method. Morphological and thermal characterizations were carried out by AFM, TG/DTG, TG/FTIR and DSC. The thermal properties of nanocomposites were compared and discussed as functions of concentration, type and surface of nanoparticles. The results obtained suggest that the base concentration for both types of nanoparticles inside the polymer matrix volume greatly adds to the increase in thermal stability up to 11 % and the glass transition temperature up to 10 °C. A similar evolution for the glass transition temperature (Tg), thermal stability temperature (TS) and dielectric permittivity (ε′) was identified, suggesting that these phenomena are mainly dominated by the same mechanisms. These results point to the possibility for the thermal parameter modulation in magnetic and ferroelectric nanocomposites by means of a suitable control of concentration and properties of the KSN and NZF nanoparticles. © 2016 Akadémiai Kiadó, Budapest, Hungary

Grossi D.A.,University of Guelph | Berton M.P.,niv Estadual Paulista | Buzanskas M.E.,niv Estadual Paulista | Chud T.C.S.,niv Estadual Paulista | And 5 more authors.
Tropical Animal Health and Production | Year: 2016

The aim of this study was to estimate genetic parameters for accumulated productivity (ACP), first calving interval (CI1), second calving interval (CI2), and mean calving interval (MCI) in Nelore beef cattle. The ACP trait is a reproduction index and comprises the total number of calves born per dam, weight of weaned calves, and age of the dam at calving. Genetic parameters were estimated by the average information restricted maximum likelihood method in two-trait analyses. The average heritability estimate for ACP was 0.17 (0.03). For CI1, CI2, and MCI, the heritability estimates were 0.02, 0.02, and 0.06, respectively. Genetic correlations between ACP with CI1, CI2, and MCI were −0.16 ± 0.47, −0.29 ± 0.53, and −0.40 ± 0.27, respectively. Despite of the low heritability estimates obtained in our study, reproduction traits should be further studied and their inclusion in the selection criteria must be evaluated in order to improve the performance of females because these traits are of great economic importance in beef cattle. Accumulated productivity could contribute to decrease the mean calving interval in Nelore cattle. © 2015, Springer Science+Business Media Dordrecht.

Garcia R.A.M.,niv Estadual Paulista | Pereira M.R.,niv Estadual Paulista | Pereira M.R.,University of Sao Paulo | Maester T.C.,niv Estadual Paulista | And 2 more authors.
Applied Biochemistry and Biotechnology | Year: 2015

One clone exhibiting lipolytic activity was selected among 30 positives from a metagenomic library of a microbe consortium specialized in petroleum hydrocarbon degradation. From this clone, a sublibrary was constructed and a metagenome contig was assembled and analyzed using the ORF Finder; thus, it was possible to identify a potential ORF that encodes a lipolytic enzyme, denoted ORF2. This ORF is composed of 1035-bp 345 amino acids and displayed 98 % identity with an alpha/beta hydrolase from Pseudomonas nitroreducens (accession number WP024765380.1). When analyzed against a metagenome database, ORF2 also showed 76 % of sequence identity with a hypothetical protein from a marine metagenome (accession number ECT55726.1). The ProtParam analyses indicated that the recombinant protein ORF2 has a molecular mass approximately 39 kDa, as expected from its amino acid sequence, and based on phylogenetic analysis and molecular modeling, it was possible to suggest that ORF2 is a new member from family V. This enzyme exhibits the catalytic triad and conserved motifs typical from this family, wherein the serine residue is located in the central position of the conserved motif GASMGG. The orf2 gene was cloned in the expression vector pET28a, and the recombinant protein was superexpressed in Escherichia coli BL21(DE3) cells. The lipolytic activity of protein bands presented in a SDS-PAGE gel was confirmed by zymogram analyses, indicating ORF2 activity. These discoveries raise the possibility of employing this protein in biotechnological applications, such as bioremediation. © 2015, Springer Science+Business Media New York.

Vendramini M.C.R.,niv. Estadual Paulista | Camargo-Mathias M.I.,niv. Estadual Paulista | De Faria A.U.,niv. Estadual Paulista | Bechara G.H.,niv. Estadual Paulista | And 2 more authors.
Parasitology Research | Year: 2012

The present study performed an analysis about the effects of andiroba seed oil (Carapa guianensis) in the ovary of Rhipicephalus sanguineus semi-engorged females; once, there are few studies about the action of natural products on the reproductive system, a vital organ for the biological success of this animal group. The results showed that andiroba oil is a potent natural agent which causes significant structural changes in the oocytes, such as the emergence of large vacuolated cytoplasmic regions, reduction in the number of yolk granules, changes in the shape of the cells, as well as impairment of genetic material. In addition, the ovary epithelium showed severe morphological changes, such as extreme structural disorganization, with highly vacuolated cells and picnotic nuclei, forming an amorphous mass. This study showed also that oocytes (mainly in the initial stages of development) and the ovary epithelium of R. sanguineus females subjected to different concentrations of andiroba oil presented morphological changes which became more numerous and intense as the concentration of the product increased. Based on the results, it can be inferred that although the defense mechanisms are developed by oocytes to recover the cellular integrity (presence of autophagic vacuoles), these cells are not able to revert the damage caused by this product. Thus, it can be concluded that although the damages caused to the oocytes by andiroba oil are comparatively less severe than the ones caused by synthetic acaricides, this product can be considered a potent natural agent that reduce and/or prevent the reproduction of R. sanguineus females, with the advantage of not causing environmental impact such as synthetic chemical acaricides. © 2012 Springer-Verlag.

Rocha F.V.,niv Estadual Paulista | Barra C.V.,niv Estadual Paulista | Franchi S.J.S.,niv Estadual Paulista | Netto A.V.G.,niv Estadual Paulista | And 2 more authors.
Journal of Thermal Analysis and Calorimetry | Year: 2011

Four new mononuclear Pd(II) complexes of the type [PdX 2(tdmPz)] {X = Cl- (1); Br- (2); I- (3); SCN- (4); tdmPz = 1-thiocarbamoyl-3,5- dimethylpyrazole} have been synthesized and characterized by elemental analysis, IR spectroscopy, 1H and 13C{1H}-NMR experiments. The thermal behavior of the complexes 14 has been investigated by means of thermogravimetry (TG) and differential thermal analysis (DTA). From the initial decomposition temperatures, the thermal stability of the complexes can be ordered in the sequence: 3 < 4 ≡ 2 < 1. The final products of the thermal decompositions were characterized as metallic palladium by X-ray powder diffraction. © 2011 Akadémiai Kiadó, Budapest, Hungary.

Vargas G.,niv Estadual Paulista | Buzanskas M.E.,niv Estadual Paulista | Guidolin D.G.F.,niv Estadual Paulista | Grossi D.A.,University of Guelph | And 5 more authors.
Tropical Animal Health and Production | Year: 2014

Beef cattle producers in Brazil use body weight traits as breeding program selection criteria due to their great economic importance. The objectives of this study were to evaluate different animal models, estimate genetic parameters, and define the most fitting model for Brahman cattle body weight standardized at 120 (BW120), 210 (BW210), 365 (BW365), 450 (BW450), and 550 (BW550) days of age. To estimate genetic parameters, single-, two-, and multi-trait analyses were performed using the animal model. The likelihood ratio test was verified between all models. For BW120 and BW210, additive direct genetic, maternal genetic, maternal permanent environment, and residual effects were considered, while for BW365 and BW450, additive direct genetic, maternal genetic, and residual effects were considered. Finally, for BW550, additive direct genetic and residual effects were considered. Estimates of direct heritability for BW120 were similar in all analyses; however, for the other traits, multi-trait analysis resulted in higher estimates. The maternal heritability and proportion of maternal permanent environmental variance to total variance were minimal in multi-trait analyses. Genetic, environmental, and phenotypic correlations were of high magnitude between all traits. Multi-trait analyses would aid in the parameter estimation for body weight at older ages because they are usually affected by a lower number of animals with phenotypic information due to culling and mortality. © 2014, Springer Science+Business Media Dordrecht.

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