Irawan R.,Nitto Denko Asia Technical Center |
Cheng Y.H.,Nitto Denko Asia Technical Center |
Ng W.M.,Nitto Denko Asia Technical Center |
Aung M.M.,Nitto Denko Asia Technical Center |
And 2 more authors.
Biosensors and Bioelectronics | Year: 2011
This paper unveils a platform to develop a compact, simple, reusable and disposable, and cost effective hand-held urinalysis device for home-health-care and doctor's office uses. A polymeric optical waveguide and colorimetric absorption were used as an optical sensor and sensing mode, respectively. The results of the tests show that the device was able to deliver quantitative results with the detection limits better than 0.1. g/L, 0.2. g/L, 0.025. g/L, and 0.1. g/L for glucose, creatinine, albumin and total protein, respectively. There are some superiorities of this device as compared to the dip-stick counterpart, that are, better sensitivity, ability to deliver quantitative results and reusability. The device is being further miniaturized to use a LED and photodiode as a light source and detector, respectively. It is believed the device has potential for early diagnostic and wellness monitoring tool. © 2011 Elsevier B.V.
Nakano Y.,Nitto Denko Asia Technical Center
Kobunshi | Year: 2012
DDS is the technology that can optimize drug administration and reduce undesired side effects. Now we cannot develop a therapeutically-effective drug product without this technology. One of the most important materials supporting the DDS technology is a polymer. Nitto Denko developed the world's first transdermal patch, the Hokunalin® Tape, based on an unique DDS technology which enables to absorb the required dosage of an asthma treatment drug via the skin. When the patch is applied to the skin, the drug penetrates the skin and is absorbed into the blood stream through the capillaries to flow throughout the body. Unlike conventional oral and inhaled formulations, the Hokunalin® Tape has the advantage of appropriately controlling the concentration of the drug in the body. This means that users can better control asthma attacks, which frequently occur in the early morning, and that the burden on caregivers is also greatly reduced. This proprietary technology is subsequently applied in the development of other transdermal patches. © 2012 The Society of Polymer Science, Japan.