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Ohashi H.,Nagoya Medical Center | Hidaka M.,Nagoya Medical Center | Hidaka M.,Kumamoto Medical Center | Sawamura M.,Nagoya Medical Center | And 14 more authors.
IRYO - Japanese Journal of National Medical Services | Year: 2011

In order to elucidate the state of red cell transfusion for patients with chronic anemia in Japan, we conducted questionnaire-based retrospective survey. A questionnaire forms were sent to 18 National Hospital Organization hospitals in January 2008, inquiring on patients repeatedly transfused for more than 6 months during the period 2003-2007. Data on 82 patients and 1,193 transfusions, during the mean period of 6. 3 months, were collected from 9 hospitals. The age of the patients varied from 20 to 89 years old (median age, 74 years old), and the underlying disorders were myelodysplastic syndromes (44 patients), aplastic anemia (16), multiple myeloma(6), myelofiborosis(6), pure red cell aplasia 6, acute leukemia(2), and others(3). The mean interval of transfusions was 15. 9 days, the mean volume of transfusion for a patient was 5. 4 units per month, and 86% of transfusion was conducted with 2 units of red cell product. Seventy-five percent of transfusions were decided to be performed in advance, without the knowledge of the hematological data of the day. The mean hemoglobin (Hb) concentrations for individual patients during the investigated period varied form 3. 2 to 9. 3g/dl (the mean for all the patients, 6. 7g/dl), and the mode section, by 0. 5g/dl, was 6. 0 to 6.4g/dl. No correlation was found between the mean Hb concentration and the mean transfusion volume per month for each patient. The Hb concentrations kept by transfusion in patients with chronic anemia in Japan are relatively low and varied widely among patients. Also, our data suggest the possibility that keeping higher Hb concentration may not necessarily increase transfusion requirement in chronically anemic patients.

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