International Journal of Theoretical Physics | Year: 2014
We observe a Quantum Brownian Motion (QBM) Model Universe in conjunction with recently established Entanglement Relativity and Parallel Occurrence of Decoherence. The Parallel Occurrence of Decoherence establishes the simultaneous occurrence of decoherence for two mutually irreducible structures (decomposition into subsystems) of the total QBM model universe. First we find that Everett world branching for one structure excludes branching for the alternate structure and in order to reconcile this situation branching cannot be allowed for either of the structures considered. Second, we observe the non-existence of a third, "emergent structure", that could approximate both structures and also be allowed to branch. Ultimately we find unless world-branching requires additional criteria or conditions, or there is a privileged structure, that we provide a valid model that cannot be properly described by the Everett Interpretation of Quantum Mechanics. © 2013 Springer Science+Business Media New York.
News Article | January 5, 2016
Every square inch of my body is sweating. I’ve been working out for only 15 minutes, and I’m not sure my legs can take any more. They are shaking uncontrollably. Later, I sit down to dinner, and my arms are so exhausted I can’t seem to pick up my spoon. I had just suffered my way through a session of high-intensity interval training, or HIIT. The regimen can be over and done in 25 minutes, warmup and cooldown included: Quick bursts of extreme physical exertion — 10 seconds to four minutes — are followed by rest periods two to five times the length of the intense parts. Studies show that HIIT increases cardiovascular fitness and can promote healthy blood glucose levels. The short workouts also increase endurance, and a recent study shows why HIIT has more endurance benefits for couch potatoes than it does for pre-trained athletes. But while HIIT may hit health in the right direction, it does little for our waistlines. And some psychologists question whether a workout that’s so uncomfortable should be promoted in public health campaigns. Will people work through the pain? Or will promotion of such difficult workouts just make people give up in frustration? In the end, whether you pick up a workout plan and stick with it may have less to do with how much time you have, and more to do with where you priorities — and your willingness to deal with pain for gain — really lie. What constitutes a HIIT workout can be a little difficult to define. Go through one bout of extreme work, and one bout of rest. Then repeat, usually three to six times in a given workout. A series of 20-second sprints and 40-second rests for 10 minutes is a HIIT workout. The seven-minute workout qualifies as high-intensity interval training, too, if interspersed with rest periods. Some types of CrossFit qualify, as well as some treadmill workouts and cycling bouts. Workout intensity varies as well. “It’s about relative intensity to the individual, not absolute intensity,” explains Kathryn Weston, an exercise scientist at Teesside University in Middlesbrough, England. “For an older person, going up a hill would be HIIT, but for an athlete, they might need to go to sprint training.” The most important thing, says Charlotte Jelleyman, an exercise physiologist at the University of Leicester in England, is “it should feel hard. For people who are more used to it, it can be all out.” And when Jelleyman says all out, she means it. “Your legs hurt, your lungs hurt, you absolutely cannot go on anymore once you’re finished,” she explains. She’s not kidding. Every time I go through a session of HIIT, I feel like I never want to do it again. The pain might be over and done with relatively quickly, but the muscle exhaustion feels eternal. The soreness can last for a week. All that pain is worth it for the health gains, studies have shown. In young to middle-aged healthy adults, HIIT produced better improvements than endurance training in the maximum amount of oxygen that a person could consume — a commonly used measure of cardiovascular health, Zoran Milaović and colleagues at the University of Nis in Serbia reported in a meta-analysis August 5 in Sports Medicine. In theory, these gains in maximal oxygen, called VO max, should mean better health. Weston says her group is especially interested in how that translates to everyday life. “It’s great VO max is improving,” Weston says. “But does it mean they are able to carry out daily tasks better? Does it translate over to real life, or is it just in the lab?” HIIT may also reduce the risk of type II diabetes. “What … HIIT does very well is basically prevent the accumulation or worsening of insulin resistance, and therefore is a very good way of preventing type II diabetes,” says Jelleyman. “It helps keep the blood glucose within a healthy range.” In a meta-analysis of 50 studies, Jelleyman and her colleagues showed that blood glucose is lower following HIIT than it is following normal continuous exercise or no exercise at all. The meta-analysis was published October 20 in Obesity Reviews. One of the most dramatic effects of HIIT is how quickly it increases muscle endurance. “HIIT is much more time-efficient than normal endurance exercise,” notes Håkan Westerblad, a muscle and exercise physiologist at the Karolinska Institute in Stockholm. “For some groups you get better faster with HIIT than with normal endurance exercise.” It’s a short workout that produces results quickly. “Some studies have shown effects in as little as two weeks,” Jelleyman notes, if the person is working out at their highest intensity. “But usually you expect at least two months for long-term changes.” And the gains even seem to affect those who aren’t gym rats by nature. “It almost favors less fit people,” Weston says. “Our data has shown it’s the people who don’t exercise, they’re the ones that might get the most benefit from it.” To look at how these big gains take place in such a short time, Westerblad and his colleagues examined 18 recreationally active men and male endurance athletes who did six rounds of 30-second bursts of high-intensity cycling followed by four minutes of rest. After the workout, the scientists took biopsies of the working muscles in the participants’ legs. When a muscle cell receives a signal to contract, tiny pumps called ryanodine receptors open, and calcium pours out of holding spaces within the cell into the cellular fluid. The high concentrations of calcium signal the muscle cell to contract. Scale this up across all muscle cells, and the whole muscle flexes. After a single HIIT workout, un-athletic guys showed fragmentation of the ryanodine receptor. Breakdown of the ryanodine receptor means calcium can leak out into the cell in a continuous drip. With only a little bit of calcium getting released, the muscle cells don’t contract. Instead, the calcium causes a little bit of stress to the cell. Cells react to this stress by increasing their endurance, making them better able to withstand the next bout of HIIT. Endurance athletes, however, didn’t get the same benefits. It turns out that the breakdown of the ryanodine receptor is a consequence of the production of free radicals — highly reactive molecules — during exercise. Westerblad says that after prolonged endurance training, the muscles of endurance athletes have “a more effective antioxidant system,” something that the nonathletes will develop as their muscles get used to broken down ryanodine receptors. Endurance athletes, he argues, had no benefit because they had nothing left to improve — they were too fit for HIIT. Westerblad and his group published their results November 2 in the Proceedings of the National Academy of Sciences. But while HIIT has proven to improve health and endurance, it may not hit us where it really counts — our weight. “The only thing it definitely doesn’t do is weight loss,” Weston says. “Generally, it has not been claimed that HIIT is effective for losing weight, per se. The energy expenditure isn’t great enough.” But, she says, some studies have shown decreases in waist circumference. “It doesn’t affect the scale but may affect how you look in the mirror.” Even so, HIIT is still good for cardiovascular health and your blood sugar. What’s not to love? Well, it turns out, people don’t love the workout itself. “I was constantly questioning whether people would want to do that kind of thing,” says Stuart Biddle, who studies psychology and active living at Victoria University in Melbourne, Australia. “We know that those much higher levels of intensity are experienced as unpleasant.” In a debate with Alan Batterham of Teesside University published July 18 in the International Journal of Behavioral Nutrition and Physical Activity, Biddle argues that pushing HIIT for everyone might just doom most people to failure. “[HIIT] has physiological benefit, of that there’s no doubt,” he says. But he thinks the workouts themselves won’t make people come back for more. “It’s unpleasant, it’s hard to do,” he explains. “I don’t think people look forward to it.” The compressed time means a HIIT workout could work for people who say they have no time to exercise, but the reality may be they don’t want to exercise at all. “When people say they don’t have time, they aren’t documenting it,” Biddle says. “It’s a statement to reflect they don’t want to spend their free time doing exercise.” To overcome this, Biddle believes that people don’t need workouts that are faster and more challenging, like HIIT. Instead, he promotes exercise that can be incorporated into daily routines. With a tough workout and no weight loss to show for it, a HIIT regimen needs to be something that you’d actually want to do. And time spent working hard doesn’t feel so bad if it’s spent doing something you love. Weston says that applying HIIT principles to the types of exercise you prefer might help you come back for another bout. “People like different things,” Weston says. “I hate the treadmill, personally. There’s a misconception that [treadmill or cycling] is the only way [HIIT] can be done.” But that’s not true. Weston says it’s really just about getting yourself to work really hard. “It could be stair climbing or boxing drills, football drills, dance drills, gym equipment,” she says. “As long as you can get that cardiovascular response that shows you’re working hard, it doesn’t matter so much about the mode of exercise.”
Djuric Z.,Nis |
Nagorni A.,Nis |
Jocic-Jakubi B.,Nis |
Dimic M.,Nis |
And 3 more authors.
Turkish Journal of Pediatrics | Year: 2012
Celiac disease (CD) is a genetically determined autoimmune enteropathy, induced by gluten ingestion. To date, different prevalences of CD in children with epilepsy have been reported. The aim of this study was to determine CD prevalence in our patients with epilepsy, using anti-tissue transglutaminase (tTG) antibodies as a screening test. One hundred twenty-five children (72 girls, 53 boys; age range: 2-18 years, mean age: 10.51 ±3.53) with idiopathic epilepsy from South East Serbia were tested for immunoglobulin (IgA) tTG antibodies. All positive patients were offered endoscopic small bowel biopsy. Biopsies were examined histopathologically in order to confirm the CD diagnosis. The control group consisted of 150 healthy children. Three patients with epilepsy were positive for IgA tTG antibodies. In all of them, small bowel biopsy was performed, and only one was proven to have CD by histopathology (Marsh IIIa grade). The prevalence of biopsy-proven CD in children with epilepsy was not significantly higher in the study group compared to controls (0.8% vs.0.6%, p>0.05). The results of this study indicate that children with idiopathic epilepsy from our region should not be routinely tested for CD.
Stojanovic D.,Institute of Pathophysiology |
Cvetkovic T.,Institute of Biochemistry |
Cvetkovic T.,Clinical Center |
Stojanovic M.,Nis |
And 3 more authors.
Annals of Transplantation | Year: 2015
Background: Renal transplant dysfunction has been shown to be an independent risk factor for cardiac, non-cardiovascular, and all-cause mortality in post-transplantation follow-up. Material/Methods: We enrolled 73 renal transplant recipients who were more than 12 months post-renal transplant surgery, had stable graft function, and were on standard immunosuppression. The purpose of the study was to observe the relation between renal dysfunction and endothelial dysfunction parameters (nitrates, asymmetric and symmetric dimethylarginine, and endothelial nitric oxide synthase), and renalase, and to hypothesize the best predictor of early renal dysfunction by multivariate modeling. The other aim was to observe differences with regard to immunosuppression. Results: Non-adjusted odds ratio showed a significant risk of reduced glomerular filtration rate in transplant recipients with increased renalase concentration (p=0.026); age-adjusted odds ratio showed a significant risk of reduced glomerular filtration rate with increased renalase concentration (p=0.042), also after multivariable adjustment (p=0.032). Increased plasma endothelial nitric oxide synthase concentration was a protective factor for glomerular filtration rate (p=0.011). After adjustment for age (p=0.045), and after multivariate modeling, endothelial nitric oxide synthase was shown to be a protective factor for glomerular filtration rate (p=0.014). Significant differences in immunosuppression were found in plasma renalase in patients maintained on cyclosporine (p=0.027). Conclusions: Renalase was shown to be strong predictor of decreased glomerular filtration rate and was significantly higher in the group of patients on cyclosporine. Endothelial nitric oxide synthase was identified as a strong protective factor for kidney function. © Ann Transplant, 2015.
Korasie C.,NMISA |
PTB - Mitteilungen Forschen und Prufen | Year: 2011
- This paper will look at the process, developing NMI's in Africa go through to establish an NMI from mostly Trade and or Legal Metrology requirements. The aim is to investigate the challenges countries are faced with in obtaining traceability and eventually accreditation. A case study will be made of the roadmap followed by NMI's that has successfully entered CMC's in the BIPM database. With limited resources the tools required to maintain these newly formed NMI's and how to increase capability in various parameters will be scrutinized.
Micic T.,City University London |
Safety and Reliability of Complex Engineered Systems - Proceedings of the 25th European Safety and Reliability Conference, ESREL 2015 | Year: 2015
In this paper we investigate probabilistic modelling and analysis options for sample RC solid slab. Variations in slab material, geometric and load slab parameters have been reviewed and set as input variables for the particular sample probabilistic model. Subsequently, FE probabilistic analysis is carried out using Monte-Carlo method and Latin Hypercube sampling technique whereas yield-line probabilistic simulations are conducted using FOSM method. Based on the resulting lower bound solution in the form cumulative distribution functions for the stress and displacement at particular location and probability of slab failure, we are able to identify the most appropriate and most efficient probabilistic structural analysis. © 2015 Taylor & Francis Group, London.
Hasan E.H.,NIS |
Haucke G.,PTB |
21st Conference on Measurement of Force, Mass and Torque Together with HARDMEKO 2010 and 2nd Meeting on Vibration Measurement, IMEKO TC3, TC5 and TC22 Conferences | Year: 2010
The creep and creep recovery are important characteristics of force transducers. Thus, this study is focused on the measurements of creep and creep recovery for transducers of different capacities. Creep measurements are carried out according to three different loading schemes, revealed that the creep values measured at maximum loads and reached after time intervals from 30 to 300 seconds like proposed in a new draft of ISO 376 from the moment of load application. The effect was higher in direct loading (one step to reach the maximum load) than those obtained from the two other schemes (chosen loading steps distributed all over the full range up to maximum load and according to automatic machine calibration (M/C) software that designed to cover all the range up to maximum load). Effect of creep on hysteresis value is also investigated.
News Article | December 28, 2016
GENOA, 28-Dec-2016 — /EuropaWire/ — Notice is hereby given that the deed of merger by incorporation of ERG Services S.p.A. into ERG S.p.A., signed on 21 December 2016, has been filed today with the Companies’ Register at the Genoa Chamber of Commerce. The effects of the merger commence from 1 January 2017. This press release issue at 12,40 p.m. (CET) on 27 December 2016, is available to the public at the offices of Borsa Italiana S.p.A., on the “Nis-Storage” authorised storage mechanism (www.emarketstorage.com) and on the Company’s website (www.erg.eu), in the section “Media/Press releases”.
Rancic D.,Nis |
Kuk K.,Academy of Criminology and Police Studies |
Pronic-Rancic O.,Nis |
Randelovic D.,Academy of Criminology and Police Studies
Smart Innovation, Systems and Technologies | Year: 2015
This article presents the effectiveness of agent-based approach in computer learning games. There are a lot of intelligent agents that are successfully used for educational purposes. However, some of them are very interesting because they can demonstrate behaviors that agents may possess; on the other hand they are used to display a set of requirements that must be met during their creation and design. Some of these requirements are similar to those used in the ITS, while the second type of behavior is quite different from them, and may even be unique. Based on this re-search, the effectiveness of games is illustrated in detail with regard to three current perspectives on agent-based approach to games: design game-based learning environment with agent, the process decisions of agent interaction and the reflection of agent recommendations and learning outcomes. Although, all perspectives are connect with the hope of better learning through games, it is criticized that the effectiveness cannot be simply answered by one of the three alone. The goal of the article is therefore to clarify the different views in case agent-personalized trend in engineering education. © Springer International Publishing Switzerland 2015.
Olneva T.V.,Gazpromneft |
2nd Conference on Forward Modelling of Sedimentary Systems: From Desert to Deep Marine Depositioned Systems | Year: 2016
There are several approaches of interpretation fluvial depositional environment sediments based on seismic and well data. This work show some examples of interpretation deposits from the west Siberia and Pannonian Basin which have the same geological settings. Due to the seismic attribute analysis, the integration of spectral decomposition with log analysis was defined in the investigated interval and facies boundaries were established. The most perspective part of the pay is the channel deposits which location were identified more precisely after spectral decomposition interpretation in the interval of interest. The lithological model obtained as a result of this project differs qualitatively from all previous models of the investigated formation, due to the following: using the predictive facies boundaries derived from the complex dynamic interpretation of the seismic data to detect geological characteristics more precisely; reconstructing the formation heterogeneity, which is very important for the well position planning and its hydrodynamic studies. © 2016, European Association of Geoscientists and Engineers, EAGE. All rights reserved.