Shiga, Japan
Shiga, Japan

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Patent
Nipro Corporation | Date: 2017-04-26

A blood circuit connector (100) includes: a main body (110) having a cylindrical shape and provided with a first opening end (120) and a second opening end (130); a plug (140) having a bottomed cylindrical shape and detachably attached to the first opening end (120); and a connection part (150) configured to connect the main body (110) and the plug (140). The plug (140) includes a side wall (142) loosely fitted to an outer circumferential surface (111) of the first opening end (120) in a state where the plug (140) is attached to the first opening end (120). The connection part (150) includes a curved part (155) expanding in a direction away from the main body (110). In the attached state, the curved part (155) is pushed in a direction approaching the outer circumferential surface (111) of the main body (110) such that the curved part (155) extends, thereby cancelling a loosely fitted state between the side wall (142) and the outer circumferential surface (111), so as to remove the plug (140) from the first opening end (120).


Patent
Nagoya University and Nipro Corporation | Date: 2017-05-17

Provided is a locking plate system for treatment of a distal radius fracture, intended to improve cooperation between screw anchors made of metal and a plate made of resin as well as to enhance matching with respect to the radius. The radius locking plate (4) is a flat laminate of intermediate molding materials that each include carbon fibers as reinforcing material and thermoplastic resin as a matrix. The screw anchor (5) includes a shaft portion (10) which has a principal thread (13) achieving a self-tapping action formed thereon and an outer circumference of a head portion of the screw anchor (5) which has an auxiliary thread (13) achieving a self-tapping action tapped thereon. A diameter of a through-hole (6) in the radius locking plate (4), which allows the radius main body (3) and the fractured bone piece (2) to be threadably fixed to the radius locking plate (4), is oversized relative to the principal thread (11), and is undersized relative to the auxiliary thread (13).


Patent
Yamanashi University, School Juridical Person The Kitasato Institute and Nipro Corporation | Date: 2017-05-17

A blood purifier comprises hollow fiber membranes allowing blood to flow inside and allowing a dialysing fluid or a filtrated fluid to flow outside. The hollow fiber membrane has an effective length of 10 mm or more and 150 mm or less. A maximum value of a permeation flux Jv obtained by dividing a volume of a permeate fluid permeating through the hollow fiber membranes by a membrane area of the hollow fiber membranes and time, is represented as Jvmax. A linear velocity of blood flowing in the hollow fiber membrane is represented as uB. A pressure difference between blood flowing inside the hollow fiber membranes and a fluid flowing outside the hollow fiber membranes is represented as TMP. When a filling blood volume into the hollow fiber membranes per unit membrane area is 20 mL/m^(2) or more and 35 mL/m^(2) or less and Jvmax/uB has a value of 0.00015 or more and 0.0006 or less, satisfied is a condition in which a TMP change rate has a value of 0.95 or more and 1.05 or less.


Patent
Nipro Corporation | Date: 2017-06-14

A needle assembly 10 includes a needle hole 16 having an inside diameter that is greater than an outside diameter of a needle 12, and by a moving-side guide 64 integrally provided to a needle tip cover 18 being engaged with a fixed-side guide 30 fixedly provided to the needle 12, a guide mechanism is provided to guide the needle tip cover 18 from a proximal end side towards a distal end side of the needle 12 while maintaining a state of noncontact with the needle 12, and to guide the needle tip cover 18 to a position where the needle tip cover 18 covers the needle tip 20 while deviating the needle tip cover 18 in a direction in which the needle hole 16 goes away from a center axis 102 of the needle 12 at a position beyond the needle tip 20, and avoiding contact of the needle tip 20 with the needle hole 16.


Patent
Nipro Corporation | Date: 2017-05-31

[Problem] To provide a balloon catheter capable of increasing the temperature of a blood vessel contacting a balloon to a target temperature in a short time by efficiently heating a heat generating member. [Solution] A balloon catheter (10) has a shaft (12) having an elastically expandable balloon (11) on the distal end side and space provided inside and allowing a fluid to flow into and flow out the balloon (11), a heat generating member (22) provided in the internal space of the balloon (11), and optical fibers (20A, 20B) which are extended up to the internal space of the balloon (11) along the shaft (12) and emit light beams input into the proximal end to the heat generating member (22) from the distal end.


A burner (10) for inner surface treatment of a medical glass container, comprising a burner body (11) having a first flow path (13) through which a fuel is circulated; anda second flow path (16) to be connected to the first flow path of the burner body, the burner having a long and narrow nozzle (12) that can be inserted into the internal space of a medical glass container or an intermediate product thereof as a processing target, and the nozzle being formed of ceramic.


Patent
Nipro Corporation | Date: 2016-05-18

A connector (2) which is detachably connected to a cylindrical section (5) is prevented from being unintentionally disconnected and from breaking. The connector (2) has an inner cylinder member (10) and an outer cylinder member (40). The inner cylinder member (10) has an engagement plate (30) protruding from the inner peripheral surface of an inner cylinder body (20) and engaging with a recess (7) formed in the outer peripheral surface of the cylindrical section (5), and also has slits (11) arranged radially and extending from the engagement plate (30) to a part of the inner cylinder body (20). The engagement between the recess (7) and the engagement plate (30) restricts the axial movement of the inner cylinder member (10) relative to the cylindrical section (5). In a state in which the outer cylinder member (40) is mounted on the inner cylinder member (10), the inner peripheral surface of the outer cylinder member is in contact with the outer peripheral surface of the inner cylinder member, and thus the displacement of the engagement plate (30) in the diameter expansion direction is restricted.


Patent
Nipro Corporation | Date: 2016-04-20

A method of determining an ESA dose, which allows a hemoglobin concentration in the blood to be stably maintained at a target value, and which can decrease a range of fluctuation of the hemoglobin concentration with respect to the target value. The method comprises the steps of: setting the target value of the hemoglobin concentration in the blood; calculating a target value of a hemoglobin production rate which allows the hemoglobin concentration to reach the target value; calculating a serum ESA concentration which allows the hemoglobin production rate to reach the target value, from a relationship between the hemoglobin production rate and the ESA concentration; and calculating an amount of administration of an ESA which gives the serum ESA concentration, from a relationship between the ESA concentration and the amount of administration of the ESA, to determine an ESA dose which allows the hemoglobin concentration to reach the target value.


To provide a blood treatment filter device capable of efficiently utilizing a blood treatment filter. A blood treatment filter device 20 has a filter sheet 26 through which a specific component among components forming blood is harder to pass than other components and a spacer sheet 27 through which the specific component is easier to pass than through the filter sheet 26. The filter sheet 26 has filter through-holes 39 disposed at intervals. The filter sheet 26 and the spacer sheet 27 are spirally wound in an overlapped state. The filter device 20 has seals 31 sealing both end portions in the longitudinal direction of a wound body 25 formed by the filter sheet 26 and the spacer sheet 27 which are spirally wound in a fluid-tight manner. The outer peripheral surface of the wound body 25 is formed by the filter sheet 26.


Patent
Nipro Corporation | Date: 2016-04-14

An injection needle 1 made of an alloy containing cobalt and molybdenum is manufactured as follows. First, a lancet cut is carried out to a pipe-like metallic material composed of the alloy containing cobalt and molybdenum to form a blade tip 3 and a blade part 5. Then, a distal end part 1A including the blade tip 3 is mechanically polished, and thereafter, the distal end part 1A is immersed in an electrolytic solution and electrolytically polished. Thus, burrs at the blade tip 3 or the like generated during mechanical polishing are removed. Since the injection needle 1 is composed of the alloy containing cobalt and molybdenum, compared to a conventional injection needle made of stainless steel, an injection needle in which the surface roughness of an inner peripheral surface of the injection needle is low and smooth can be provided.

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