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Patent
Nippon Zoki Pharmaceutical Co. and Technoplan Inc. | Date: 2015-05-18

To provide a sludge treatment method and a sludge treatment system suppressing the fuel costs which can be utilized in the existing treatment facilities that drying and discharging after dehydrating a sludge as a useful improvement for the facility. This invention provides the solution means including a dehydration step of obtaining a dehydrated sludge, a liquefaction step of obtaining a slurry-like sludge, a branching step of branching a digested sludge, a vacuum deaeration step of deaerating a first digested sludge, a reprocessing step of ejecting a high-temperature steam and returning a concentrated digested sludge, a dehydration separation treatment step of separating a second digested sludge, a step of deaerating a digested sludge, a branching step of branching the mixed phase fluid, a step of returning a first mixed phase fluid, and a step of returning a second mixed phase fluid.


Patent
Nippon Zoki Pharmaceutical Co. | Date: 2013-09-20

A novel coumarin derivative or a pharmaceutically acceptable salt thereof and also to provide a pharmaceutical agent containing such a compound as an active ingredient is provided. The coumarin derivative or a pharmaceutically acceptable salt thereof exhibits an excellent suppressive action to the destruction of cartilage and suppressive action to the proliferation of synovial cells in a pharmacological test where the release of sulfated glycosaminoglycans (sGAG) and the proliferation of synovial cells are used as indicators whereby it is very useful as an active ingredient of a pharmaceutical composition such as a preventive or therapeutic agent for arthropathy such as osteoarthritis or chronic rheumatoid arthritis.


Patent
Nippon Zoki Pharmaceutical Co. and Nagoya Industrial Science Research Institute | Date: 2013-04-26

An object of the present invention is to provide an analgesic effective in a prophylactic or a therapy for various pain diseases. The present invention is to provide an analgesic containing at least one member selected from a trans-2-decenoic acid derivative represented by the formula (1) and a pharmaceutically acceptable salt thereof as an active ingredient: (In the formula, Y is O, NR or S, R is hydrogen atom, alkyl group, dialkylaminoalkyl group or the like and W is a substituent such as dialkylaminoalkyl group). The analgesic of the present invention containing the compound as an active ingredient is highly useful as a prophylactic or therapeutic agent for various pain diseases such as the pain caused by osteoarthritis (e.g., knee osteoarthritis and hip osteoarthritis).


Patent
Nippon Zoki Pharmaceutical Co. | Date: 2013-12-27

The present invention provides a cinnamic acid amide derivative having an excellent analgesic action. The cinnamic acid amide derivative of the present invention is a compound showing excellent analgesic actions to not only a nociceptive pain model animal but also a neuropathic pain model animal, which is very useful as an agent for treating various pain diseases showing acute or chronic pains or neuropathic pains.


Patent
Nippon Zoki Pharmaceutical Co. and The Regents Of The University Of California | Date: 2015-09-18

The synthesis of collagen and proteoglycan in chondrocytes, such as intervertebral disc cells, articular chondrocytes and meniscal cells is promoted by administration of an extract from inflamed tissue inoculated with vaccinia virus.

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