Kita-ku, Japan
Kita-ku, Japan

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Water-soluble black Chinese (Pu-Ehr) tea extract has been demonstrated to elicit antiobese effects in animals. We investigated the effects of black Chinese tea extract intake in 36 preobese Japanese adults in a 12-week double-blind randomized placebo-controlled group comparison study using powdered barley tea with or without black Chinese tea extract. All subjects ingested barley tea with (333 mg) or without (0 mg) black Chinese tea extract before each of three meals daily. In the black Chinese tea extract-treated group, the mean pretreatment values of body weight and body mass index significantly decreased from 8 weeks after intake (versus controls). Black Chinese tea extract intake may be useful for weight control and prevention of obesity development in humans. © 2015 Nippon Supplement, Inc.


Kubota K.,Fukuoka University | Sumi S.,Fukuoka University | Tojo H.,Fukuoka University | Sumi-Inoue Y.,Fukuoka University | And 4 more authors.
Nutrition Research | Year: 2011

Water-soluble black Chinese (Pu-Erh) tea extract (BTE), which contains high gallic acid content, has been demonstrated to elicit antiobese effects in animals. Because gallic acid is related with the reduction of visceral fat and cholesterol contents and improvement of obesity in animals, we investigated the effects of BTE intake on 36 preobese Japanese adults (body mass index [BMI], >25- <30 kg/m 2) in a 12-week double-blind, randomized, placebo-controlled group comparison study using powdered barley tea with or without (placebo) BTE. A follow-up 4-week period after BTE intake termination was monitored to observe the withdrawal effect. All subjects ingested barley tea with or without BTE (333 mg) before each of the 3 daily meals. In the BTE-treated group, the mean pretreament values of body weight and BMI significantly decreased after intake and after BTE withdrawal. However, the corresponding values scored significant differences only from 8 weeks after intake (vs the placebo-treated group). The mean values of the waist circumference indicated a similar tendency. Furthermore, coronal navel section (same anatomical position) images of computed tomography of all BTE- and non-BTE-treated subjects revealed that the visceral fat areas (cm 2) were significantly (P < .05) less in the former 12 weeks after BTE ingestion. Measured biochemical parameters did not indicate significant differences, and BTE-treated subjects did not complain of any adverse effects (abdominal distension, etc). Ingestion of BTE exhibited significant effects in reducing the mean waist circumference, BMI, and visceral fat values and might be useful for weight control and prevention of obesity development (or metabolic syndrome) in humans. © 2011.


PubMed | Nippon Supplement Inc
Type: Journal Article | Journal: Bioscience, biotechnology, and biochemistry | Year: 2013

Chinese black tea extract (CBTE) fermented with Aspergillus sp. significantly promoted hair growth after 2 weeks of topical application in shaved 6 week-old male C3H/He mice. The hair growth-promoting effect of CBTE was potentiated synergistically by capsaicin, which has no effect on hair growth by itself. CBTE displayed an affinity for estrogen receptor (ER), with an IC50 value of 74.8 g/mL. This effect of CBTE might be mediated by the ERs, since a similar effect induced by orally administered soy isoflavone, a mixture of ERs ligands, has been reported to be synergistically potentiated by capsaicin.


PubMed | Nippon Supplement Inc.
Type: Comparative Study | Journal: Phytotherapy research : PTR | Year: 2012

The antiobesity effects of Chinese black tea (Pu-erh tea) and of gallic acid (GA) were investigated using in vitro and in vivo assays. Chinese black tea extract (BTE) and GA inhibited pancreatic lipase activity in a dose-dependent manner in vitro; the IC(inhibitory concentration)(50) values were 101.6 and 9.2 g/mL, respectively. Black tea extract (50, 100 mg/kg body weight (b.w.)) and GA (15, 45 mg/kg b.w.) significantly suppressed the elevation of blood triglyceride after oral administration of a corn oil emulsion (8 mL oil/kg b.w.) to male ddY mice. Moreover, the antiobesity effects of BTE and GA were also evaluated in a mouse model of diet-induced obesity. Female ddY mice were divided into seven groups; normal diet (ND) group, high fat diet (HFD) group, BTE (0.2% and 0.6% of diets) groups, and GA (0.007%, 0.02% and 0.1% of diets) groups; the experimental groups were fed the test diets for 12 weeks. The BTE 0.6% and GA 0.1% groups showed significant suppression of weight gain. The weight of parametrial adipose tissue was strongly correlated with the body weight. These results suggest that GA contributes to the antiobesity effect of BTE as an active constituent by inhibiting pancreatic lipase activity.


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Nippon Supplement Inc. | Date: 2010-01-19

Soy extract derived from fermented soybeans known as Touchi.

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