Nippon Suisan Kaisha Ltd.

Tokyo, Japan

Nippon Suisan Kaisha Ltd.

Tokyo, Japan
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Patent
Nippon Suisan Kaisha Ltd. and Mochida Pharmaceutical Co. | Date: 2017-07-26

Provided are: an eicosapentaenoic acid alkyl ester-containing composition which comprises 96-99 area% of an eicosapentaenoic acid alkyl ester, wherein the content of an arachidonic acid alkyl ester is 0.7 area% or less, and the content of mono-trans forms of the eicosapentaenoic acid alkyl ester is 2.5 area% or less; a method for producing a high-concentration eicosapentaenoic acid alkyl ester-containing composition, which comprises performing rectification on an eicosapentaenoic acid alkyl ester-containing composition with the degree of vacuum being 0.2 Torr or less and at a whole-column temperature 190C or less, and performing a concentration treatment on the rectified composition using chromatography, the eicosapentaenoic acid alkyl ester-containing composition being obtained by alkyl esterifying a feed oil containing eicosapentaenoic acid.


Patent
Nippon Suisan Kaisha Ltd. | Date: 2017-08-02

Provided is a contact sensor device for fish, said contact sensor device being capable of adjusting the elastic force of an elastic member in accordance with variations in the magnitude of the tensile force on a mark during feeding which varies depending on the growth state of relatively large fish, and said elastic member preventing overloading of a pressure sensor and breakage of a fishing line. The present invention includes: a fishing line 22, an end part of which is attached to a mark 24 to be pulled by a fish; a pressure sensor 18 that senses pressure; a pressing piece 28 that is connected to the other end part of the fishing line 22, and transmits the tensile force acting upon the fishing line 22 to an operation part 26 of the pressure sensor 18; and an elastic member 32 that prevents overloading of the pressure sensor 18 by the pressing piece 28 and breakage of the fishing line 22. The elastic member 32 is provided with an elastic force adjustment means 38 that adjusts the elastic force of the elastic member 32 in accordance with the tensile force acting upon the pressing piece 28.


A highly unsaturated fatty acid or a highly unsaturated fatty acid ethyl ester that has been produced using as a feedstock oil a fat or oil that contains highly unsaturated fatty acids as constituent fatty acids and which has been reduced in the contents of environmental pollutants, wherein among the dioxins contained, polychlorinated dibenzoparadioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) are contained in amounts of less than 0.05 pg-TEQ/g and coplanar PCBs (Co-PCBs) in amounts of less than 0.03 pg-TEQ/g. Also disclosed is a method for producing the highly unsaturated fatty acid or highly unsaturated fatty acid ethyl ester by the steps of removing free fatty acids and environmental pollutants by thin-film distillation from a feedstock oil, ethyl esterifying the resulting fat or oil, and refining the same by rectification and column chromatography.


A method for producing monovalent unsaturated free fatty acids having 20 and/or 22 carbons or low-grade alcohol esters thereof, said method involving the following: obtaining free fatty acids or low-grade alcohol esters through the hydrolysis or alcoholysis of oils and fats derived from marine products; carrying out distillation on the free fatty acids or low-grade alcohol esters, and reducing the concentration of fatty acids with 18 or less carbons in the low-grade alcohol esters or free fatty acids; and collecting fractions of monovalent unsaturated free fatty acids having 20 and/or 22 carbons or low-grade alcohol esters thereof by column chromatography based on reversed-phase distribution.


Patent
Nippon Suisan Kaisha Ltd. and Biogenic Co. | Date: 2015-02-05

A method for increasing efficiency of a method for producing astaxanthin by culturing a microalga. A method for producing astaxanthin in which astaxanthin is produced in an algal body by culturing a microalga, wherein photoirradiation is performed using both a blue LED of peak wavelength from 420 to 500 nm and a red LED of peak wavelength from 620 to 690 nm, at least during an astaxanthin-producing culturing phase of a culturing period. The ratio of the blue LED of peak wavelength from 420 to 500 nm and the red LED of peak wavelength from 620 to 690 nm is preferably from 1:19 to 19:1 by photon flux density, and the photon flux densities are each preferably not less than 20 mol/m^(2)/s.


A method for producing monovalent unsaturated free fatty acids having 20 and/or 22 carbons or low-grade alcohol esters thereof, said method involving the following: obtaining free fatty acids or low-grade alcohol esters through the hydrolysis or alcoholysis of oils and fats derived from marine products; carrying out distillation on the free fatty acids or low-grade alcohol esters, and reducing the concentration of fatty acids with 18 or less carbons in the low-grade alcohol esters or free fatty acids; and collecting fractions of monovalent unsaturated free fatty acids having 20 and/or 22 carbons or low-grade alcohol esters thereof by column chromatography based on reversed-phase distribution.


Patent
Nippon Suisan Kaisha Ltd. | Date: 2016-09-12

A method of increasing blood cholecyctokinin level is described. The method includes administering to a subject in need of increasing blood cholecyctokinin level a therapeutically effective amount of palmitoleic acid, a salt thereof, or an ester thereof.


A microbial oil comprising: a specific amount of at least one polyunsaturated fatty acid having at least 20 carbon atoms in fatty acid alkyl ester form and/or in free fatty acid form; and specific amount of thermally-produced fatty acid having from 16 to 22 carbon atoms in a fatty acid alkyl ester form and/or a free fatty acid form. A production method thereof comprising: providing a starting oil containing at least one polyunsaturated fatty acid having at least 20 carbon atoms in an alkyl ester form and/or a free fatty acid form obtained from microbial biomass; performing a rectification of the starting oil under specific conditions; and obtaining the aforementioned microbial oil. A concentrated microbial oil obtained using the production method described above, and a production method thereof. An agent for treating or preventing an inflammatory disease comprising the microbial oil or the concentrated microbial oil.


A compound derived from the culture product of an actinomycete and having an antitumor activity is provided. Provided is a compound represented by any one of formulas (I), (II) and (III) or an optical isomer thereof or a pharmaceutically acceptable salt thereof which can be isolated from the culture fluid of an actinomycete which belongs to the genus Streptomyces, wherein R^(1), R^(2), R^(5 )and R^(6 )each independently represent a hydrogen atom, a methyl group, a hydroxymethyl group, a hydroxyl group, or a double bond by which R^(1 )and R^(2 )or R^(5 )and R^(6 )are bonded; R^(3), R^(4), R^(7 )and R^(8 )each independently represent a methyl group or a hydroxymethyl group; and R^(9 )represents a hydrogen atom or a hydroxyl group.


Provided is a method for producing a processed food which is produced by continuously heating/molding a fluid raw material containing a protein, a lipid, and water. A method for heating a material to be heated continuously by an internal heating system while moving the material in a tube comprising: (a) arranging the tube vertically or substantially vertically (a tilt of not greater than 15) and heating/molding a mixture while feeding the mixture upward from a bottom in the tube and/or (b) heating/molding the mixture while rotating the tube around a rotation axis, the rotation axis being a center line in a length direction of the tube. The internal heating system is preferably microwave heating, Joule heating, or high-frequency heating. The method for producing a processed protein food employs the heating/molding method for production of a processed protein food wherein a material to be heated, which is a fluid mixture containing a protein, a lipid, and water, is molded by thermally coagulating the mixture continuously by an internal heating system while moving the mixture in a tube.

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