Nagoya-shi, Japan
Nagoya-shi, Japan

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Adachi H.,Nippon Menard Cosmetic Co. | Murakami Y.,Nippon Menard Cosmetic Co. | Tanaka H.,Nippon Menard Cosmetic Co. | Nakata S.,Nippon Menard Cosmetic Co.
Experimental dermatology | Year: 2014

Although ultraviolet (UV) rays cause premature aging of human skin, which is called photoaging, its detailed mechanisms are not known. Stratifin (SFN), a member of the 14-3-3 protein family, is secreted by keratinocytes on human skin, and has an effect on gene expression in other cells. In this study, the association of SFN with the mechanism of photoaging was investigated. The effect of UVB irradiation on SFN expression in epidermal keratinocytes was examined by in vitro and in vivo studies. In addition, the effects of SFN on epidermal keratinocytes and dermal fibroblasts were examined. SFN mRNA expression and protein levels increased significantly in UVB-irradiated keratinocytes. SFN significantly decreased filaggrin and serine palmitoyltransferase mRNA expression in epidermal keratinocytes and hyaluronan synthase 2 mRNA expression in dermal fibroblasts. In addition, it was reconfirmed that SFN induces the downregulation of collagen content through changes of COL-1, MMP-1 and MMP-2 mRNA expressions. Furthermore, the expression level of SFN mRNA was significantly higher in sun-exposed compared with that in sun-shielded skin. These results suggest that SFN affects the water-holding capacity, barrier function and dermal matrix components in photoaging skin. An increase of SFN triggered by UVB irradiation may be one of the causes of alterations observed in photoaging skin. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.


Trademark
Nippon Menard Cosmetic Co. | Date: 2013-01-25

Hair color; Hair colorants; Hair coloring preparations; Hair dyes; Hair rinses; Hair coloring rinses.


Trademark
Nippon Menard Cosmetic Co. | Date: 2015-10-20

Cosmetics; eyeliner cosmetics; eyeliners; eyeliner pencils; brush pencil tipped eyeliners in the nature of a pen with a tip like a brush; eyebrow cosmetics; eyebrow pencils; cosmetics for eyelashes; mascara; make-up preparations.


Trademark
Nippon Menard Cosmetic Co. | Date: 2013-12-27

COSMETICS; FACE AND BODY POWDERS, FACE AND BODY CREAMS, ROUGES, MASKS, MASCARA, COSMETIC COMPACTS, FACE AND EYE MAKE-UP, FACE AND EYE MAKE-UP REMOVER, IMPLEMENTS FOR APPLYING EYE AND LIPLINER, NAMELY, LIPSTICK, AND EYE LINE BRUSHES, EYEBROW PENCILS, EYE LINER PENCILS, LIP LINER PENCILS, LIPSTICKS, LIP GLOSS, COSMETIC PENCILS, AND COSMETIC KITS CONTAINING ONE OR MORE OF THE FOREGOING.


Trademark
Nippon Menard Cosmetic Co. | Date: 2014-01-29

Soaps, dentifrices, cosmetics, natural perfumery prepared from vegetables, natural perfumery prepared from animals, synthetic perfumery, compound perfumery and incenses and fragrances.


Trademark
Nippon Menard Cosmetic Co. | Date: 2015-07-10

Cosmetic creams for skin care, namely, cleansing cream, washing cream, massage cream, and moisturizing cream; cosmetic lotions for skin care, namely, skin toning lotion, moisturizing lotion; cosmetics in the form of milks, lotions, and emulsions; cosmetic make-up; cosmetic make-up preparations, namely, makeup base lotion, make-up base cream, powder foundation make-up, liquid foundation make-up, face powder, lipstick and liquid lip gloss.


Trademark
Nippon Menard Cosmetic Co. | Date: 2013-10-03

Cosmetics.


Trademark
Nippon Menard Cosmetic Co. | Date: 2014-01-29

Soaps, namely, soaps for personal use, liquid soap, bath soap, skin soaps and medicated soaps; dentifrices; cosmetics; natural perfumery prepared from vegetables; natural perfumery prepared from animals; synthetic perfumery; compound perfumery; incenses and fragrances.


Trademark
Nippon Menard Cosmetic Co. | Date: 2013-01-08

Soaps, dentifrices, cosmetics, natural perfumery prepared from vegetables, natural perfumery prepared from animals, synthetic perfumery, compound perfumery, and incenses and fragrances.


Trademark
Nippon Menard Cosmetic Co. | Date: 2015-10-20

Cosmetics and non-medicated toiletries; * namely, skin masks; * facial masks; facial cream masks; scrubbing facial, cosmetic, body, and skin masks; scrubbing cream facial, cosmetic, body, and skin masks; facial creams * ; all the aforesaid goods containing herbs *.

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