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Cai X.,Lishui Central Hospital | Guan J.,Yanbian University | Ren S.,Lishui Central Hospital | Wei Y.,Lishui Central Hospital | And 3 more authors.
Experimental and Therapeutic Medicine | Year: 2016

Internal carotid artery dissection (ICAD) is a major cause of ischemic stroke in young and middle-aged patients. Patients may be asymptomatic or present with symptoms ranging from headache and neck pain to severe cerebral ischemic events. Conventional treatment is medical anticlotting therapy or involves the use of interventional tools, such as endovascular treatment. Anticoagulation or antiplatelet therapy are the primary treatment modalities used to prevent thromboembolic complications from arterial dissections, however, they are unsuitable in certain cases of dissecting aneurysms. In the current study reports the case of a 52-year-old male patient presenting with the primary complaint of left limb weakness. Computed tomography angiography revealed a right ICAD located in the oropharyngeal segment. Subsequently, digital subtraction angiography was performed to assess the oropharyngeal segment. Antithrombotic therapy resulted in no improvement; therefore, endovascular treatment with the insertion of a Willis covered stent was performed, resulting in an improved outcome. © 2016, Experimental and Therapeutic Medicine. All rights reserved. Source


Zhou C.,Ningbo Yinzhou Peoples Hospital | Pan C.,Ningbo Yinzhou Peoples Hospital | Shan A.,Ningbo Yinzhou Peoples Hospital | He Y.,Ningbo Yinzhou Peoples Hospital | And 2 more authors.
Experimental and Clinical Cardiology | Year: 2014

Objective: To research the expression and clinical significance of adiponectin (APN) in tunica media of radial artery in uremic patients. Methods: Specimens of radial arteries were taken from 80 uremic patients during the arteriovenous fistula surgery. Vascular calcification was evaluated by the staining of alizarin red. The expressions of APN was determined immunohistochemically.According to the Grade of calcification and the expression of APN in the membrane of the radial artery, Semi-quantitative analysis was done for comparison between groups. Results: Varying degrees of medial calcification was found in 37 uremic patients (46.25%). All of the radial arteries with calcification showed expressions of APN.The expression of APN was negatively correlated with the degree of medial calcification,with statistical significance (r=-0.476,P<0.05). Conclusion: The incidence of vascular calcification was high in uremic patients. APN is visibly related to the radial arterial medial calcification and may play a role in the occurrence and development of the radial artery medial calcification. Source

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