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Gupta R.,Nair Hospital and Dental College | Debnath N.,JKK Nataraja Dental College and Hospital | Nayak P.A.,NIMS Dental College and Hospital | Khandelwal V.,Index Institute of Dental science
BMJ Case Reports | Year: 2014

Gingival squamous cell carcinoma (GSCC) is a relatively rare malignant neoplasm of the oral cavity. It represents less than 10% of diagnosed intraoral carcinoma. Because of its close proximity to the teeth and periodontium, the tumour can mimic tooth-related benign infl ammatory conditions. This case report describes a patient diagnosed with GSCC presenting as localised periodontitis. Copyright 2014 BMJ Publishing Group. All rights reserved.

Agarwal V.,NIMS Dental College and Hospital | Gupta M.,JKK Nataraja Dental College and Hospital | Gupta A.,Government of Rajasthan
Indian Journal of Public Health Research and Development | Year: 2014

There has been a tremendous development in the field of tissue engineering in past two decades that can be applied in the dentistry. With the more recent advances in understanding the cellular and molecular basis controlling the development and regeneration of tooth structures, great changes are expected in conventional dental therapies. These biologically based procedures can result in continued root development, increase in dentinal wall thickness and induction of apical closure even in the case of necrotic immature permanent teeth. In this review role of stem cells in bio- root engineering will be discussed.

Reddy Y.G.,NIMS Dental College and Hospital | Sharma R.,NIMS Dental College and Hospital | Singh A.,NIMS Dental College and Hospital | Agarwal V.,NIMS Dental College and Hospital | Agrawal V.,NIMS Dental College and Hospital
Journal of Clinical and Diagnostic Research | Year: 2013

Aim: This study has compared the Shear Bond Strengths (SBSs) of ceramic brackets and metal brackets. Materials and Method: Forty freshly extracted, human maxillary first premolars were selected for bonding. They were equally bonded with ceramic brackets (Transcend series 6000) and metal brackets (Mini Dynalock Straight wire brackets). A no - mix orthodontic adhesive system was used. Their shear bond strengths were measured by using the Instron universal machine. Results: The mean bond strength of the ceramic brackets was 20.68 ± 3.89 Mpa and that of the metal brackets was 12.15 ± 1.32 MPa. Conclusion: The shear bond strength of the ceramic brackets was found to be superior than that of the metal brackets.

Nandita K.P.,Manipal University India | Boaz K.,Manipal University India | Suman E.,Kasturba Medical College | Hegde A.,Kasturba Medical College | Mahesh C.P.,NIMS Dental College and Hospital
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2013

To compare the phagocytic activity and intracellular killing activity of Polymorphonuclear Leukocytes in peripheral blood of patients with Oral Squamous Cell Carcinoma and healthy controls.Study comprised of thirty patients with histologically proven squamous cell carcinoma of the oral cavity and ten controls that were age - and sex - matched healthy non - hospitalized patients that included five smokers and five non - smokers. Phagocytosis and intracellular killing activity were assayed.Student's t- test (SPSS version 11.0) and Annova were used to compare the healthy patients and oral carcinoma patients.Present study demonstrated suppression in both phagocytic as well as intracellular killing activity of PMNs in patients with oral squamous cell carcinoma, when compared to that of healthy controls.A significant suppression of both phagocytosis and intracellular killing of candidal species by neutrophils was observed in the patients with Oral cancer. The relatively low candidacidal activity of neutrophils is suggestive of cellular immunosuppression which is often induced in various malignancies.

Jain S.,NIMS Dental College and Hospital | Narang P.,NIMS Dental College and Hospital | Sharma R.,NIMS Dental College and Hospital | Agarwal V.,NIMS Dental College and Hospital
Journal of Clinical and Diagnostic Research | Year: 2013

The success of the root canal treatment is based on a thorough knowledge of the normal tooth, the root and the root canal morphology, which include variations. Tooth rotation is a common finding in the premolar-molar region, but a 180 degree rotation of the maxillary central incisor is extremely rare and it has not documented anywhere in the dental literature. This case report describes the aesthetic correction of a maxillary central incisor with a 180 degree rotation and two root canals.

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