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Sarkar A.,Midnapore Medical College | Saha A.,Post Graduate Institute of Medical Education and Research | Roy S.,Post Graduate Institute of Medical Education and Research | Pathak S.,Nilratan Sirkar Medical College and Hospital | Mandal S.,Bankura Sammillani Medical College BSMC
Journal of Clinical and Diagnostic Research | Year: 2015

Introduction: The vermiform appendix in human is considered to be a vestigial organ by most of the authors. Absence of appendix is already reported in Indian population. Whether the human appendix is performing any function is debatable but when present it can create trouble. So if there is no appendix we can escape the ill-effects of the organ. With this hope the study has been done to see whether the appendix is really going to be rudimentary or absent or not.Marerials and Methods: Length, external diameter, number of lymphoid follicles, maximum diameter of the follicle or submucous coat, thickening of the muscle coat and seromucosal thickening of freshly removed appendix from human cadavers were seen. After fixation in 10% formal saline tissues were stained with haematoxylin-eosin stain and photographs were taken. The results had been tabulated and statistically correlated.Result: The parameters like number of lymphoid follicles, length and diameter all are changed as per the age advancement which is strictly indicating some functional activities of the organ which is against the idea of vestigiality of the appendix.Conclusion: Human appendix cannot be called a vestigial organ unless the functional inactivity is proved. Lymphoid changes which occur after birth to provide the gut immunity is needed to be proved by further studies. There might be incidental absence or rudimentary appendix in human body, but that does not indicate that we would not have any appendix in future. © 2015, Journal of Clinical and Diagnostic Research. All rights reserved. Source


Dolai T.K.,Nilratan Sirkar Medical College and Hospital | Dutta S.,Nilratan Sirkar Medical College and Hospital | Bhattacharyya M.,Nilratan Sirkar Medical College and Hospital | Ghosh M.K.,Nilratan Sirkar Medical College and Hospital
Hemoglobin | Year: 2012

India is in the thalassemia belt of the world. Both α- and β-thalassemia (α- and β-thal) are found in West Bengal, a state in the eastern part of India. There was no systematic large published study to investigate the prevalence rates of different hemoglobinopathies in West Bengal. This study was conducted in school and college students, newly married couples and pregnant women after proper counseling in the rural areas of five districts of West Bengal state in eastern India. Thalassemia testing was done using high performance liquid chromatography (HPLC). A total of 35,413 individuals were screened for hemoglobinopathies. β-Thalassemia trait was found in 10.38%, Hb E [β26(B8)Glu→Lys] trait in 4.30%, sickle cell trait in 1.12%, borderline Hb A2 value 0.73%, low Hb A2 0.68% and Hb D trait 0.37%. This is the first study that addresses the prevalence of different hemoglobinopathies in rural areas of West Bengal. The prevalence of β-thal trait is higher in West Bengal than other parts of India. This data is likely to be helpful in planning screening programs in rural areas of West Bengal, India. © 2012 Informa Healthcare USA, Inc. Source

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