Tokyo, Japan
Tokyo, Japan

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Patent
Nikkiso Company Ltd | Date: 2016-07-13

Provided is a blood purification apparatus which can continue to accurately monitor a blood purification treatment state even if treatment conditions are changed during blood purification treatment. The blood purification apparatus can perform real-time monitoring on the blood purification treatment state, based on a concentration change in a discharge solution which is obtained by an arithmetic device (12). The blood purification apparatus includes a treatment condition change device (13) that sets or changes treatment conditions as requested, and that causes a discharge solution concentration sensor (5) to previously detect concentration of the discharge solution under the respective treatment conditions, and a storage device (14) that stores the concentration of the discharge solution under the respective treatment conditions which is detected by the discharge solution concentration sensor (5) in the treatment condition change device (13), as a first predetermined value corresponding to the respective treatment conditions. When the treatment conditions are changed during blood purification treatment, the arithmetic device (12) obtains the concentration change in the discharge solution, based on the first predetermined value corresponding to the changed treatment conditions among the first predetermined values stored in the storage device (14).


Patent
Nikkiso Co. | Date: 2016-04-27

There is provided a reciprocating pump in which it is possible to monitor pump volumetric efficiency and a flow rate with ease and accuracy. A reciprocating pump includes a pump chamber; a suction port which enables a liquid to be suctioned into the pump chamber; a discharge port which enable a liquid in the pump chamber to be discharged; a plunger 7 which is capable of reciprocating in the pump chamber by a motor M; check valves are disposed between the pump chamber and a flow route on the suction port side and a flow route on the discharge port side, are openable and closable in response to a change in a liquid pressure in the pump chamber, which is produced due to the reciprocating of the plunger 7 a detection device that is able to detect a period of time during which the check valve is in an opened state or in a closed state in a predetermined cycle; and an arithmetic device that performs an arithmetic operation to obtain pump volumetric efficiency or a flow rate based on a comparison between a period of detection time detected by the detection device and a period of time during which the check valve is in the opened state or in the closed state in the predetermined cycle during normal operation.


Patent
Nikkiso Company Ltd | Date: 2016-09-21

There are provided a blood purification apparatus and a priming method thereof which can reliably perform air bubble purging of a blood purification device while workability is maintained during priming. During the priming, an air purging step is performed by causing a blood pump (4) to perform reverse rotation, and electromagnetic valves (V3) and (V6) are brought into an opened state so as to open the overflow line (L) and a priming solution supply line (Lc) and so as to discharge a priming solution from an overflow line (L) while supplying a dialysate functioning as the priming solution from the priming solution supply line (Lc).


This system for in-body-cavity liquid perfusion of a circulating type (10), which circulates a liquid such as an isotonic solution perfused within the body cavity, suppresses an excessive increase in internal pressure that would lead to breakage of a hollow fiber membrane module (20). A drain valve (62) is connected to a drain port (60) of the hollow fiber membrane module (20). A pressure sensor (28, 32) measures the internal pressure of the hollow fiber membrane module (20). A control unit (21) opens the drain valve (62) on the basis of the internal pressure of the hollow fiber membrane module (20) measured by the pressure sensor (28, 32), draining foreign matter from the hollow fiber membrane.


Provided are: a novel method for controlling the concentration of free chlorine easily; a sterilization method employing the method; and a novel apparatus for controlling the concentration of free chlorine easily. In the disclosed method, the concentration of free chlorine is controlled using a plurality of electrodes. The method includes a process of (i) and a process of (ii) in this order. In the process of (i), the potential of a first anode and the potential of a first cathode are adjusted in an aqueous solution (30) containing chloride ions so as to increase the concentration of free chlorine in the aqueous solution (30). In the process of (ii), the potential of a second anode and the potential of a second cathode are adjusted in the aqueous solution (30) so as to decrease the concentration of free chlorine in the aqueous solution (30). The difference between the potential of the second anode and the potential of the second cathode in the process of (ii) is smaller than the difference between the potential of the first anode and the potential of the first cathode in the process of (i).


Patent
Nikkiso Company Ltd | Date: 2016-02-26

Provided is a blood purification apparatus which can continue to accurately monitor a blood purification treatment state even if treatment conditions are changed during blood purification treatment. The blood purification apparatus can perform real-time monitoring on the blood purification treatment state, based on a concentration change in a discharge solution which is obtained by an arithmetic device. The blood purification apparatus includes a treatment condition change device that sets or changes treatment conditions as requested, and that causes a discharge solution concentration sensor to previously detect concentration of the discharge solution under the respective treatment conditions, and a storage device that stores the concentration of the discharge solution under the respective treatment conditions which is detected by the discharge solution concentration sensor in the treatment condition change device, as a first predetermined value corresponding to the respective treatment conditions. When the treatment conditions are changed during blood purification treatment, the arithmetic device obtains the concentration change in the discharge solution, based on the first predetermined value corresponding to the changed treatment conditions among the first predetermined values stored in the storage device.


Patent
Nikkiso Company Ltd | Date: 2016-05-09

There are provided a blood purification apparatus and a priming method thereof which can reliably perform air bubble purging of a blood purification device while workability is maintained during priming. During the priming, an air purging step is performed by causing a blood pump to perform reverse rotation, and electromagnetic valves and are brought into an opened state so as to open the overflow line (L) and a priming solution supply line and so as to discharge a priming solution from an overflow line while supplying a dialysate functioning as the priming solution from the priming solution supply line.


Patent
Nikkiso Company Ltd | Date: 2016-06-10

An object is to provide a co-injection member which can smoothly collect a liquid of an internal flow route, which can smoothly inject a liquid into the internal flow route, and which can reliably prevent congestion of the liquid in the internal flow route. A co-injection member includes a main body that can be connected to a blood circuit through which blood is circulated, an internal flow route that is formed inside the main body, and that can circulate the liquid of the blood circuit, an inlet flow route that is formed inside the main body, and that introduces the blood into the internal flow route, an outlet flow route that is formed inside the main body, and that can discharge the blood of the internal flow route, and a rubber member that is attached to an opening formed in the main body, and that separates the inside and the outside of the internal flow route from each other. The co-injection member can collect the blood of the internal flow route and can inject the other liquid into the internal flow route via the rubber member. The inlet flow route extends while a diameter thereof gradually decreases toward a position shifted from a center of the internal flow route.


Patent
Nikkiso Company Ltd | Date: 2016-10-19

An object is to provide a co-injection member which can smoothly collect a liquid of an internal flow route, which can smoothly inject a liquid into the internal flow route, and which can reliably prevent congestion of the liquid in the internal flow route. A co-injection member (1) includes a main body (2) that can be connected to a blood circuit through which blood is circulated, an internal flow route () that is formed inside the main body (2), and that can circulate the liquid of the blood circuit, an inlet flow route (A) that is formed inside the main body (2), and that introduces the blood into the internal flow route (), an outlet flow route (B) that is formed inside the main body (2), and that can discharge the blood of the internal flow route (), and a rubber member (4) that is attached to an opening (2c) formed in the main body (2), and that separates the inside and the outside of the internal flow route () from each other. The co-injection member (1) can collect the blood of the internal flow route () and can inject the other liquid into the internal flow route () via the rubber member (4). The inlet flow route (A) extends while a diameter thereof gradually decreases toward a position shifted from a center (P) of the internal flow route ().


Patent
Nikkiso Co. | Date: 2016-04-13

In a water purification apparatus (100), a flow passage (40) has an inlet port (42) and an outlet port (44) of water. A light source (30) irradiates the water, passing through the flow passage (40), with ultraviolet light. The light source (30) has a light emitting diode that emits the ultraviolet light whose wavelength is contained in a bandwidth of 220 nm or above to less than 300 nm, and the optical output in this wavelength bandwidth is in a range of 1 W to 50 W. The flow passage (40) passes the water at a flow rate of 5 mL/second to 250 mL/second. The flow passage (40) is formed by a wall surface having a tubular shape. A window (26) through which the ultraviolet light is passed is provided in at least part of the wall surface.

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