Tokyo, Japan
Tokyo, Japan

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Patent
Nikkiso Company Ltd | Date: 2016-12-20

A dialysate-extracting apparatus is provided in which scattering of dialysate that may occur when an opening-and-closing device is detached from a collecting port can be prevented and the cleanliness of the collecting port can be assuredly maintained. The dialysate-extracting apparatus includes a dialysate-extracting device connected to a dialysate flow route and having a collecting port from which dialysate flowing in the dialysate flow route is collectable, and an opening-and-closing device detachable from and attachable to the dialysate-extracting device in such a manner as to open and close the collecting port and including a seal portion that seals the collecting port in a closed state. When the opening-and-closing device is detached from the dialysate-extracting device, a part of the opening-and-closing device that is on an inner side with respect to the seal portion is bendable and displaceable toward the collecting port.


Patent
Nikkiso Company Ltd | Date: 2017-05-03

A blood purification apparatus is provided that can easily and accurately determine before treatment whether or not blocking of liquid by a check valve (18) is appropriate. In the blood purification apparatus including a blood circuit, a dialyzer (1), a dialysate introduction line (L1) and a dialysate discharge line (L2), pressure detection device ( to ), a dialysate extraction device (10), a dialysate supply line (La), and a check valve (18) that blocks flow of a liquid from the blood circuit to the dialysate introduction line (L1), there are provided a control means (19) that makes it possible to generate a pressure difference between a side of the blood circuit and a side of the dialysate introduction line (L1) across the check valve (18), a monitor means (20) that makes it possible to monitor a change in a detection value of the pressure detection device based on the pressure difference, and a determination means (21) that makes it possible to determine whether or not blocking of liquid by the check valve (18) is appropriate based on the change in the detection value of the pressure detection device.


Patent
Nikkiso Company Ltd | Date: 2016-12-22

A blood purification apparatus is provided that can easily and accurately determine before treatment whether or not blocking of liquid by a check valve is appropriate. In the blood purification apparatus including a blood circuit, a dialyzer, a dialysate introduction line and a dialysate discharge line, pressure detection device, a dialysate extraction device, a dialysate supply line, and a check valve that blocks flow of a liquid from the blood circuit to the dialysate introduction line, there are provided a control means that makes it possible to generate a pressure difference between a side of the blood circuit and a side of the dialysate introduction line across the check valve, a monitor means that makes it possible to monitor a change in a detection value of the pressure detection device based on the pressure difference, and a determination means that makes it possible to determine whether or not blocking of liquid by the check valve is appropriate based on the change in the detection value of the pressure detection device.


Patent
Nikkiso Company Ltd | Date: 2016-12-28

A clamp device for a flexible tube which can minimize the sealing area and prevent leakage of fluid and achieve easy release of the clamp device of a flexible tube. A clamp device for a flexible tube comprising: one branch formed with a first projection; the other branch formed with a second projection opposing to the first projection; an intermediate part connecting the one branch and the other branch each other; and an engaging part formed on a tip end of the other branch adapted to be engaged with an engaged part formed on a tip end of the one branch; flow of fluid within the flexible tube laid between the first projection and the second projection being able to be blocked by elastically bending the intermediate part and engaging the engaging part and the engaged part each other to clamp the flexible tube between the first and second projection wherein the clamp device comprises a positioning part for positioning the first and second projections in the longitudinal direction of the flexible tube under the clamped state of the flexible tube with engaging the engaging part and the engaged part each other.


Patent
Nikkiso Company Ltd | Date: 2017-05-03

An object of the present invention is to provide a clamp device for a flexible tube which can minimize the sealing area and also prevent leakage of fluid as well as achieve easy release of the clamp device of a flexible tube. According to the present invention, there is provided a clamp device for a flexible tube comprising one branch formed with a first projection; the other branch formed with a second projection opposing to the first projection; an intermediate part connecting the one branch and the other branch each other; and an engaging part formed on a tip end of the other branch adapted to be engaged with an engaged part formed on a tip end of the one branch; flow of fluid within the flexible tube laid between the first projection and the second projection being able to be blocked by elastically bending the intermediate part and engaging the engaging part and the engaged part each other to clamp the flexible tube between the first projection and the second projection characterized in that the clamp device further comprises a positioning part for performing a relative positioning of the first and second projections in the longitudinal direction of the flexible tube under the clamped state of the flexible tube with engaging the engaging part and the engaged part each other.


Patent
Nikkiso Co. | Date: 2017-05-03

A dialysate-extracting apparatus is provided in which scattering of dialysate that may occur when an opening-and-closing device is detached from a collecting port can be prevented and the cleanliness of the collecting port can be assuredly maintained. The dialysate-extracting apparatus includes a dialysate-extracting device (10) connected to a dialysate flow route and having a collecting port (10d) from which dialysate flowing in the dialysate flow route is collectable, and an opening-and-closing device (H) detachable from and attachable to the dialysate-extracting device (10) in such a manner as to open and close the collecting port (10d) and including a seal portion (14a) that seals the collecting port (10d) in a closed state. When the opening-and-closing device (H) is detached from the dialysate-extracting device (10), a part of the opening-and-closing device (H) that is on an inner side with respect to the seal portion (14a) is bendable and displaceable toward the collecting port (10d).


Patent
Nikkiso Company Ltd | Date: 2017-03-07

A blood purification apparatus that is capable of performing a liquid spill prevention operation and uniformizing the amount of air introduced through an opened portion. The blood purification apparatus includes a dialysate introduction line that allows dialysate to be introduced into a dialyzer; a dialysate discharge line that allows the dialysate to be discharged from the dialyzer; coupling tools that allow free switching between a connected state which causes a closed circuit, and an opened state which causes the closed circuit to be opened to form an opened portion; and a control means that performs a liquid spill prevention operation in which external air is introduced through the opened portion. An air detection means, by which air introduced through the opened portion is detectable, is provided in the vicinity of the coupling tools, and the control means stops the liquid spill prevention operation when air is detected by the air detection means.


Patent
Nikkiso Company Ltd | Date: 2017-03-14

A blood purification apparatus capable of achieving a simplified configuration and switching between hemodialysis treatment (HD), hemofiltration treatment (HF), and hemodiafiltration treatment (HDF) as well as selecting from pre-dilution, post-dilution and pre and post-dilution easily and smoothly. The blood purification apparatus includes: a valve means 3 that is capable of closing and opening a dialysate introduction line and a dialysate supply line L3 in any manner, and a control unit 5 that operates the valve means 3 to allow any treatment to be performed selected from hemodialysis treatment in which the dialysate supply line L3 is closed while the dialysate introduction line L1 is opened, hemofiltration treatment in which the dialysate supply line L3 is opened while the dialysate introduction line L1 is closed, and hemodiafiltration treatment in which hemodialysis and hemofiltration are performed concurrently by alternately closing and opening the dialysate introduction line L1 and the dialysate supply line L3.


Provided are: a novel method for controlling the concentration of free chlorine easily; a sterilization method employing the method; and a novel apparatus for controlling the concentration of free chlorine easily. In the disclosed method, the concentration of free chlorine is controlled using a plurality of electrodes. The method includes a process of (i) and a process of (ii) in this order. In the process of (i), the potential of a first anode and the potential of a first cathode are adjusted in an aqueous solution (30) containing chloride ions so as to increase the concentration of free chlorine in the aqueous solution (30). In the process of (ii), the potential of a second anode and the potential of a second cathode are adjusted in the aqueous solution (30) so as to decrease the concentration of free chlorine in the aqueous solution (30). The difference between the potential of the second anode and the potential of the second cathode in the process of (ii) is smaller than the difference between the potential of the first anode and the potential of the first cathode in the process of (i).


Patent
Nikkiso Company Ltd | Date: 2016-05-09

There are provided a blood purification apparatus and a priming method thereof which can reliably perform air bubble purging of a blood purification device while workability is maintained during priming. During the priming, an air purging step is performed by causing a blood pump to perform reverse rotation, and electromagnetic valves and are brought into an opened state so as to open the overflow line (L) and a priming solution supply line and so as to discharge a priming solution from an overflow line while supplying a dialysate functioning as the priming solution from the priming solution supply line.

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