Tokyo, Japan
Tokyo, Japan

Nihon University is a private research university in Japan, which is considered the country's largest institution of higher learning. Yamada Akiyoshi, the Minster of Justice, founded Nihon Law School in October 1889.Most of the university's campuses are in the Kantō region, the vast majority in Tokyo or surrounding areas, though two campuses are as far away from Tokyo as Shizuoka Prefecture and Fukushima Prefecture. Unlike the separate campus systems of many American universities , these campuses do not represent separate universities, but normally accommodate a single college or school .The university comprises a federation of colleges and institutes known for having produced numerous CEOs of Japanese companies. The College of Art , located right next to Ekota train station in Tokyo's Nerima ward, is well known as it produces many artists who represent Japan in photography, theater, and cinema. In addition, the university has over 20 affiliated high schools bearing its name across Japan, from which a significant number of students go on to study at the institution as undergraduates. Wikipedia.

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A three-dimensional printing system (1) includes: a head (2) to which a first continuous material (FL) including a resin and a second continuous material (FB) including fibers are fed; a platform (3) on which a printing material based on the first and second continuous materials from the head is stacked; a cutting device (10) which is capable of cutting at least fibers; and a controller (5) which controls an operation device including at least one of the head, the platform, and the cutting device.


Patent
Shimadzu Corporation and Nihon University | Date: 2017-03-22

Seat members 31 are held in a state of being movable with respect to first slide members 21 or second slide members 22 correspondingly. By rotating screws 39 in directions to increase the distances d between surfaces A of the first slide members 21 or the second slide members 22 and surfaces B of the seat members 31, chucks 25 are moved in directions to increase the distance between the chucks to apply pretension to a test piece correspondingly. When backlash in a force transmission system from a support part to the respective chucks 25 is eliminated, a biaxial tensile test is started.


A three-dimensional printing system (1) includes: a head (2) to which a first continuous material (FL) including a resin and a second continuous material (FB) including fibers are fed; a platform (3) on which a printing material based on the first and second continuous materials from the head is stacked; a cutting device (10) which is capable of cutting at least fibers; and a controller (5) which controls an operation device including at least one of the head, the platform, and the cutting device.


Patent
Shimadzu Corporation and Nihon University | Date: 2014-05-14

Seat members 31 are held in a state of being movable with respect to first slide members 21 or second slide members 22 correspondingly. By rotating screws 39 in directions to increase the distances d between surfaces A of the first slide members 21 or the second slide members 22 and surfaces B of the seat members 31, chucks 25 are moved in directions to increase the distance between the chucks to apply pretension to a test piece correspondingly. When backlash in a force transmission system from a support part to the respective chucks 25 is eliminated, a biaxial tensile test is started.


Yamada S.,Nihon University | Makishima M.,Nihon University
Trends in Pharmacological Sciences | Year: 2014

The vitamin D receptor (VDR), a receptor for the secosteroid 1α,25-dihydroxyvitamin D3 [1,25(OH)2D3], is a promising drug target in the treatment of bone and mineral disorders, cancer, autoimmune disease, infection, and cardiovascular disease. Indeed, approximately 100 nonsecosteroidal VDR modulators (VDRMs) have been developed. Analysis of X-ray crystal structures reveals: (i) nonsecosteroidal VDRMs bind to VDR in a position similar to 1,25(OH)2D3; (ii) hydrogen bond interactions between ligands and VDR are the most important for VDR binding; (iii) hydrophobic interactions and CH-π interactions in aromatic ligands are also important for VDR binding; and (iv) exchange of C-O-C linkage to C-CH2-C linkage in VDRMs increases transactivation activity, probably as a result of an entropic effect of solvation/desolvation of molecules. Several VDRMs have better therapeutic efficacy when compared to 1,25(OH)2D3 in experimental models of cancer and osteoporosis with less induction of hypercalcemia, a major potential adverse effect in the clinical application of VDR ligands. © 2014 Elsevier Ltd.


Patent
System Instruments Co. and Nihon University | Date: 2016-03-09

To provide an electrophoresis method and an electrophoresis device which can reduce difficulty in operation while implementing sufficient staining. An electrophoresis device 10 includes a temperature gradient tank 12, a dispenser 14, a holder storage cabinet 16, a photographing unit 18, a PCR device 20, a chip rack 22, a chip disposal box 24, a DC power unit 26, a control unit 30, an arm 32, and a liquid feeder 34. A holder 100 and a cassette 150 removably attached to the holder 100 are put on the temperature gradient tank 12. The control unit 30 controls a carrying device 16a, the arm 32, the liquid feeder 34, the temperature gradient tank 12, an excitation light source 18a and a camera 18b in the photographing unit 18, and the DC power unit 26. The control unit 30 prestores a program for executing the control operation in its internal memory.


Patent
Nihon University | Date: 2016-01-20

To provide a safe and stable medicine useful for prevention and treatment of prostate cancer. A novel PI polyamide is acquired that recognizes and binds to a specific base sequence of an Oct1 gene binding sequence present in a transcriptional regulatory region (AR response region) of an ACSL3 gene and regulating the transcription activity of AR. This leads to the provision of an ACSL3 gene expression inhibitor and a preventive and/or therapeutic agent of prostate cancer containing the PI polyamide as an active ingredient.


Patent
Nihon University | Date: 2016-05-11

Provided is a magnetized coaxial plasma generation device having increased magnetization efficiency and capable of improving power conservation and reducing the thermal load on a coil. The magnetized coaxial plasma generation device generating spheromak plasma comprises: an external electrode (1); an internal electrode (2); a plasma generation gas supply section (3); a power supply circuit (4); a bias coil (5); a pulse power supply (6) for the bias coil; a magnetic flux conservation section (7); and a control section (8). The bias coil (5) is disposed inside the internal electrode and generates a bias magnetic field between the external and internal electrodes. The pulse power supply (6) for the bias coil pulse-drives the bias coil. The magnetic flux conservation section (7) is disposed outside the external electrode. The control section controls the pulse power supply for the bias coil so as to pulse-drive the bias coil for a time sufficient to apply a bias magnetic field necessary to generate the spheromak plasma between the external and internal electrodes and within a time shorter than a skin time of the magnetic flux of the bias magnetic field into the magnetic flux conservation section.


Patent
Nihon University | Date: 2016-04-13

It is a problem of the present invention to provide a convenient and safe periodontal tissue regeneration material and provide a method of regenerating a periodontal tissue. The present invention provides a periodontal tissue regeneration material comprising dedifferentiated fat cells (DFAT) as the convenient and safe periodontal tissue regeneration material. The present invention provides a method of regenerating a periodontal tissue with the periodontal tissue regeneration material.


Otsuki J.,Nihon University
Coordination Chemistry Reviews | Year: 2010

Porphyrins are promising components to be used in molecular electronics due to their rich electronic/photonic properties. Preparation of supramolecular architectures of porphyrins on solid surfaces would constitute a basis for further development toward molecular circuitry or other constructs for molecular electronics applications. Assemblies on surfaces can be probed with scanning tunneling microscopy (STM) at submolecular resolutions to reveal the arrangements and conformations of molecules on an individual molecule basis. The electronic characteristics within a single porphyrin molecule can also be probed by means of the same technique. This review summarizes the status quo of STM studies on porphyrins on surfaces with regard to their assemblies, structures, and electronic properties at the single molecule level. © 2010 Elsevier B.V.

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