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Palmeri M.L.,Duke University | Qiang B.,Rochester College | Qiang B.,Nielsen Company | Chen S.,Rochester College | Urban M.W.,Rochester College
IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control | Year: 2017

Ultrasound shear wave elastography is emerging as an important imaging modality for evaluating tissue material properties. In its practice, some systematic biases have been associated with ultrasound frequencies, focal depths and configuration, and transducer types (linear versus curvilinear), along with displacement estimation and shear wave speed estimation algorithms. Added to that, soft tissues are not purely elastic, so shear waves will travel at different speeds depending on their spectral content, which can be modulated by the acoustic radiation force (ARF) excitation focusing, duration, and the frequency-dependent stiffness of the tissue. To understand how these different acquisition and material property parameters may affect the measurements of shear wave velocity, the simulations of the propagation of shear waves generated by ARF excitations in viscoelastic media are a very important tool. This paper serves to provide an in-depth description of how these simulations are performed. The general scheme is broken into three components: 1) simulation of the 3-D ARF push beam; 2) applying that force distribution to a finite-element model; and 3) extraction of the motion data for post-processing. All three components will be described in detail and combined to create a simulation platform that is powerful for developing and testing algorithms for academic and industrial researchers involved in making quantitative shear-wave-based measurements of tissue material properties. © 1986-2012 IEEE.

Tribune owns or operates 42 television stations in 33 markets, cable network WGN America, digital multicast network Antenna TV, minority stakes in the TV Food Network and CareerBuilder, and a variety of real estate assets. Tribune's stations, a list of which is available in Tribune's most recent Form 10-K filed on March 1, 2017, consist of 14 FOX, 12 CW, 6 CBS, 3 ABC, 2 NBC, 3 MyNetworkTV affiliates and 2 independent stations. The group includes stations in the top three DMAs in the country, seven in the top 10 and 34 in the top 50 DMAs.1 "This is a transformational acquisition for Sinclair that will open up a myriad of opportunities for the company," commented Chris Ripley, President and CEO of Sinclair.  "The Tribune stations are highly complementary to Sinclair's existing footprint and will create a leading nationwide media platform that includes our country's largest markets. The acquisition will enable Sinclair to build ATSC 3.0 (Next Generation Broadcast Platform) advanced services, scale emerging networks and national sales, and integrate content verticals. The acquisition will also create substantial synergistic value through operating efficiencies, revenue streams, programming strategies and digital platforms." "This will be the largest acquisition in our company's history, and I want to thank everyone from the Sinclair team, as well as our advisors and bankers who made this possible," commented David Smith, Executive Chairman of Sinclair.  "Television broadcasting is even more relevant today, especially when it comes to serving our local communities.  Tribune's stations allow Sinclair to strengthen our commitment to serving local communities and to advance the Next Generation Broadcast Platform.  This acquisition will be a turning point for Sinclair, allowing us to better serve our viewers and advertisers while creating value for our shareholders." "Today's announcement is the culmination of an extensive strategic review, which has delivered significant value to our stockholders," said Peter Kern, Tribune's Chief Executive Officer.  "Since we announced the strategic review 15 months ago, we have streamlined the business, monetized non-core assets, strengthened our balance sheet and returned more than $800 million to stockholders -- all of which has resulted in a 50% increase in stockholder value.  We are extremely proud to join Sinclair, and we're excited that Tribune stockholders and employees will have the opportunity to participate in the long-term growth of the combined company." The transaction has been unanimously approved by the Boards of Directors of both companies and is anticipated to close and fund in the fourth quarter of 2017.  Completion of the transaction is subject to approval by Tribune's stockholders, as well as customary closing conditions, including approval by the Federal Communications Commission ("FCC"), and antitrust clearance. Sinclair expects to fund the purchase price at closing through a combination of cash on hand, fully committed debt financing to be provided by JPMorgan Chase Bank, N.A., Royal Bank of Canada, Deutsche Bank AG New York Branch and Deutsche Bank Securities Inc. and by accessing the capital markets. In order to comply with FCC ownership requirements and antitrust regulations, Sinclair may sell certain stations in markets where it currently owns stations. Such divestitures will be determined through the regulatory approval process. Including the Tribune acquisition (before any related divestitures), all previously announced pending transactions, and pro forma for expected synergies, Sinclair's 2015 and 2016 media revenues would have been $4.070 billion and $4.603 billion, respectively.  The $6.6 billion enterprise value represents an average pro forma EBITDA multiple of less than 7.0x on the core television and entertainment business and is expected to add over 40% pro forma 2016/2017 free cash flow per share accretion2. J.P. Morgan Securities LLC acted as exclusive financial advisor.  Fried, Frank, Harris, Shriver & Jacobson LLP, Pillsbury Winthrop Shaw Pittman LLP and Thomas & Libowitz P.A. acted as legal advisors to Sinclair in connection with this transaction. Moelis & Company and Guggenheim Securities acted as financial advisors and Debevoise & Plimpton LLP and Covington & Burling LLP acted as legal advisors to Tribune in connection with this transaction. The senior management of Sinclair intends to hold a conference call to discuss the acquisition of Tribune on Monday, May 8, 2017 at 11:00 a.m. ET.  After the call, an audio replay will be available at  The press and the public will be welcome on the call in a listen-only mode.  The dial-in number is (877) 407-8033. A slide presentation is available during the call and can be accessed at Tribune will release its first quarter results, and host an investor call, as previously scheduled, prior to market open, on Wednesday, May 10, 2017.  The investor call will begin at 8:30 a.m. ET and can be accessed by dialing 888-317-6003 (domestic) or 412-317-6061 (international).  The confirmation code is 2831845. Sinclair is one of the largest and most diversified television broadcasting companies in the country. Pro forma for the Tribune acquisition (before any related divestitures) and all previously announced pending transactions, the Company will own, operate and/or provide services to 233 television stations in 108 markets.  The Company has multiple emerging networks as well as being affiliated with all the major networks. Sinclair is a leading local news provider in the country and a producer of live sports content. Sinclair's content is delivered via multiple-platforms, including over-the-air, multi-channel video program distributors, and digital platforms. The Company regularly uses its website as a key source of Company information which can be accessed at Tribune Media Company (NYSE: TRCO) is home to a diverse portfolio of television and digital properties driven by quality news, entertainment and sports programming. Tribune is comprised of Tribune Broadcasting's 42 owned or operated local television stations reaching approximately 50 million households, national entertainment cable network WGN America, whose reach is approximately 80 million households, Tribune Studios, and a variety of digital applications and websites commanding 60 million monthly unique visitors online. Tribune also includes Chicago's WGN-AM and the national multicast networks Antenna TV and THIS TV. Additionally, Tribune owns and manages a significant number of real estate properties across the U.S. and holds a variety of investments, including a 32% interest in CareerBuilder, LLC and a 31% interest in Television Food Network, G.P., which operates Food Network and Cooking Channel. For more information please visit Certain statements and information in this communication may be deemed to be "forward-looking statements" within the meaning of the Federal Private Securities Litigation Reform Act of 1995. Forward-looking statements may include, but are not limited to, statements relating to Tribune's and Sinclair's objectives, plans and strategies, and all statements (other than statements of historical facts) that address activities, events or developments that Tribune and Sinclair intend, expect, project, believe or anticipate will or may occur in the future. These statements are often characterized by terminology such as "believe," "hope," "may," "anticipate," "should," "intend," "plan," "will," "expect," "estimate," "project," "positioned," "strategy" and similar expressions, and are based on assumptions and assessments made by Tribune's and Sinclair's management in light of their experience and their perception of historical trends, current conditions, expected future developments, and other factors they believe to be appropriate. Any forward-looking statements in this communication are made as of the date hereof, and Tribune and Sinclair undertake no duty to update or revise any such statements, whether as a result of new information, future events or otherwise. Forward-looking statements are not guarantees of future performance. Whether actual results will conform to expectations and predictions is subject to known and unknown risks and uncertainties, including: risks and uncertainties discussed in the reports that Tribune and Sinclair have filed with the Securities and Exchange Commission (the "SEC"); general economic, market, or business conditions; risks associated with the ability to consummate the business combination between Tribune and Sinclair and the timing of the closing of the business combination; the risk that a regulatory approval that may be required for the proposed transaction is delayed, is not obtained or is obtained subject to conditions that are not anticipated; pricing fluctuations in local and national advertising; future regulatory actions and conditions in the television stations' operating areas; competition from others in the broadcast television markets; volatility in programming costs; the ability to successfully integrate Tribune's and Sinclair's operations and employees; the ability to realize anticipated benefits and synergies of the business combination; the potential impact of announcement of the business combination or consummation of the transaction on relationships, including with employees, customers and competitors; and other circumstances beyond Tribune's and Sinclair's control. Refer to the section entitled "Risk Factors" in Tribune's and Sinclair's annual and quarterly reports filed with the SEC and in the Form S-4 to be filed by Sinclair with the SEC at a future date for a discussion of important factors that could cause actual results, developments and business decisions to differ materially from forward-looking statements. No Offer or Solicitation / Additional Information and Where to Find It: This communication is for information purposes only and does not constitute an offer to sell or the solicitation of an offer to buy any securities, or a solicitation of any vote or approval, nor shall there be any sale, issuance or transfer of securities in any jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such jurisdiction.  No offer of securities shall be made except by means of a prospectus meeting the requirements of Section 10 of the Securities Act of 1933, as amended. This communication is being made in respect of a proposed business combination involving Sinclair and Tribune. In connection with the proposed transaction, Tribune and Sinclair intend to file relevant materials with the SEC, including a Registration Statement on Form S-4 to be filed by Sinclair that will include a preliminary proxy statement of Tribune and that will also constitute a prospectus of Sinclair. The information in the preliminary proxy statement/prospectus will not be complete and may be changed. Tribune will deliver the definitive proxy statement to its shareholders as required by applicable law.  This communication is not a substitute for any prospectus, proxy statement or any other document that may be filed with the SEC in connection with the proposed business combination. INVESTORS AND SECURITY HOLDERS OF SINCLAIR AND TRIBUNE ARE URGED TO READ THE DEFINITIVE PROXY STATEMENT/PROSPECTUS AND OTHER DOCUMENTS FILED WITH THE SEC CAREFULLY AND IN THEIR ENTIRETY WHEN THEY BECOME AVAILABLE BECAUSE THEY WILL CONTAIN IMPORTANT INFORMATION ABOUT THE PROPOSED TRANSACTION. Investors and security holders will be able to obtain these materials (when they are available) and other documents filed with the SEC free of charge at the SEC's website, Copies of documents filed with the SEC by Sinclair (when they become available) may be obtained free of charge on Sinclair's website at or by directing a written request to Sinclair at 10706 Beaver Dam Road, Hunt Valley, MD 21030, Attention:  Lucy A. Rutishauser.  Copies of documents filed with the SEC by Tribune (when they become available) may be obtained free of charge on Tribune's website at Tribune and its directors, executive officers and certain other members of management and employees may be deemed to be participants in the solicitation of proxies in respect of the proposed transaction. Information regarding these persons who may, under the rules of the SEC, be considered participants in the solicitation of Tribune stockholders in connection with the proposed transaction is set forth in the proxy statement/prospectus described above filed with the SEC. Additional information regarding Tribune's executive officers and directors is included in Tribune's  proxy statement for its 2017 annual meeting of shareholders filed with the SEC on March 24, 2017 which can be obtained free of charge from the sources indicated above. 1 "DMAs" are television designated market areas according to the Nielsen Company. The rankings are in terms of size of the DMA out of the 210 generally recognized DMAs in the United States. 2 Sinclair management considers free cash flow to be an indicator of Sinclair's assets' operating performance. Sinclair management also believes that free cash flow is a commonly used measure of valuation for companies in the broadcast industry. In addition, this measure is frequently used by industry analysts, investors and lenders as a measure of valuation for broadcast companies, although their definitions of free cash flow may differ from Sinclair's definition. Sinclair believes this measure serves as a valuable assessment tool for investors to identify potential trends in the company's performance.  For the definition of free cash flow, please refer to Sinclair's website: To view the original version on PR Newswire, visit:

McDonald J.S.,Rochester College | McDonald R.J.,Rochester College | Fan J.,Nielsen Company | Lanzino G.,Rochester College | And 2 more authors.
Journal of Stroke and Cerebrovascular Diseases | Year: 2015

Background We sought to measure the impact of the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST) findings on clinical practice by studying trends in carotid artery stenting (CAS) and carotid endarterectomy (CEA) utilization before and after publication of CREST in a large US multihospital database. Methods The Premier Perspective Database was used to identify inpatient CEA and CAS procedures performed from January 2006 to March 2013. Patients were subclassified by age (<70/≥70 years) and presentation (symptomatic/asymptomatic). CEA and CAS volumes were compared before and after the publication of CREST (July 2010) using an interrupted time series model. Results A total of 121,157 CEA and 18,503 CAS procedures performed at 445 medical centers were identified. There was no significant change observed in the overall number of CEA procedures performed after CREST publication relative to the pre-existing trend (P =.08); however, there was a significant increase in the overall number of CAS procedures performed (delta of 40 cases, P =.0179) in patients aged younger than 70 years (delta of 24 cases, P =.0008), 70 years or older (delta of 25 cases, P =.0047), and asymptomatic patients (delta of 39 cases, P =.0159). The overall percentage of CEA procedures performed in relation to all revascularization procedures was significantly lower after CREST publication overall (delta, -1.5%; P =.041) for patients aged younger than 70 years (delta, -2.4%; P <.0001) and asymptomatic patients (delta, -1.5%; P =.035). Conclusions In this large sample of US hospitals, performance of CAS significantly increased after the publication of the CREST study. © 2015 National Stroke Association.

Li X.,University of Tennessee at Knoxville | Nukala S.,Nielsen Company | Mohebbi S.,University of Tennessee at Knoxville
International Journal of Advanced Manufacturing Technology | Year: 2013

This paper examines the influence of competition among supply chain partners on product demand. A power law demand function that depends on product pricing and shelf-space allocation (SSA) is used. The exponents in the power law are given by the elasticities of demand. In order to achieve the optimal pricing and SSA strategies in the presence of competition, game-theory-based methodologies-Cournot and Stackelberg games-are employed. For each type of game, a Nash equilibrium is achieved by optimizing the profit as a function of demand and price. A case study is presented to demonstrate the potential of this methodology. The results of this study indicate (1) how to achieve optimal pricing and SSA strategies, (2) how manufacturers can influence demand for a product, (3) that both prices and profits decrease using the Stackelberg game as compared with the Cournot game, and (4) that coordination beyond simple knowledge of price would be beneficial for improving overall profits. © 2013 Springer-Verlag London.

Shin E.,University of Illinois at Chicago | Johnson T.P.,University of Illinois at Chicago | Rao K.,Nielsen Company
Social Science Computer Review | Year: 2012

Web surveys are being increasingly incorporated into national survey data collection programs in the United States because of their cost/time-efficiencies. Yet, response rates and data quality issues in web surveys remain important challenges. As a basic study designed to better understand data quality in a mixed mode national survey, this article investigates the degree to which web versus mail survey modes affect unit and item responses. Findings indicate that the web survey mode produces a lower unit response rate compared to the mail mode. However, the web mode elicits higher data quality in terms of item responses to both closed- and open-ended questions. These mode effects on data quality remain after sociodemographic variables are held constant. Given the increasing integration of web survey questionnaires into mixed mode studies, additional research is necessary to understand and document the processes that underlie mode differences when responding to self-administered surveys. © The Author(s) 2012.

Peek M.E.,University of Chicago | Wilkes A.E.,University of Chicago | Roberson T.S.,University of Chicago | Goddu A.P.,University of Chicago | And 6 more authors.
Health Affairs | Year: 2012

Interventions to improve health outcomes among patients with diabetes, especially racial or ethnic minorities, must address the multiple factors that make this disease so pernicious. We describe an intervention on the South Side of Chicago-a largely lowincome, African American community-that integrates the strengths of health systems, patients, and communities to reduce disparities in diabetes care and outcomes. We report preliminary findings, such as improved diabetes care and diabetes control, and we discuss lessons learned to date. Our initiative neatly aligns with, and can inform the implementation of, the accountable care organization-a delivery system reform in which groups of providers take responsibility for improving the health of a defined population. © 2011 Project HOPE-The People-to-People Health Foundation, Inc.

Walton L.,Nielsen Company | Bergstrom J.C.R.,Fors Marsh Group | Hawkins D.C.,Fors Marsh Group | Pierce C.,Nielsen Company
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) | Year: 2014

Asking respondents to record their activity in a diary can be a difficult task due to retrospective reporting and cognitive burden as well as the complexity of the data collection tool. Diary questionnaires typically require multiple pieces of information including demographics, activities, and duration over a data collection period. Like other questionnaire types, visual design principles can be used to help people perceive and understand what is being asked of them during diary measurement. Eye tracking, a technology that allows us to passively study people's eye movements, has been used mostly for questionnaire testing within the survey research field. This study focuses on using eye tracking and other user experience measures to analyze how respondents perceive, understand and experience different designs of the paper Nielsen TV Diary. We used eye tracking to gain insights into visual elements that draw attention, the amount of text that respondents read (e.g., terms/instructions), and how respondents complete the survey. This paper centers on the collecting and analyzing of qualitative and quantitative measures of the user experience, including eye-tracking data (e.g., fixation count, time to fixate), participants' verbalizations, self-reported satisfaction, and performance data (e.g., accuracy, steps to complete). We also provide recommendations about the design of the paper diary based on the user experience and eye-tracking results. © 2014 Springer International Publishing.

Choi H.-J.,Nielsen Company | Wohlgenant M.K.,North Carolina State University | Zheng X.,North Carolina State University
American Journal of Agricultural Economics | Year: 2013

Using household scanner data and a discrete choice modeling approach, we estimate demand for milk products at the micro-level and compute the distribution of welfare effects from introducing organic milk across households with different characteristics within the partial equilibrium framework. The price effects of introducing organic milk are larger for low-income households than for high-income households, and the differences in the variety effects of introducing organic milk to groups with various levels of education are larger than the differences in the variety effects among groups with different income levels. Policy implications of these findings are discussed. © The Author (2013). Published by Oxford University Press on behalf of the Agricultural and Applied Economics Association. All rights reserved.

Campbell E.G.,Massachusetts General Hospital | Campbell E.G.,Harvard University | Vogeli C.,Massachusetts General Hospital | Vogeli C.,Harvard University | And 6 more authors.
JAMA Internal Medicine | Year: 2015

IMPORTANCE: For the past decade, more attention and concern has been directed toward financial relationships between the life science industry and physicians. Relationships between industry and institutional review board (IRB) members represent an important subclass that has the potential to broadly influence decisions regarding medical research. OBJECTIVES: To study the nature, extent, and perceived consequences of industry relationships among IRB members in academic health centers and to compare our results with findings from 2005. DESIGN, SETTING, AND PARTICIPANTS: A survey mailed to IRB members from the 115 most research-intensive medical schools and teaching hospitals in the United States from January 16 through May 16, 2014. The survey included questions identical to those used in 2005. Data analysis was conducted from June through October 2014. MAIN OUTCOMES AND MEASURES: The frequency of industry relationships among IRB members and the perceived effect of those relationships on IRB-related activities. RESULTS: We found no significant change inthe percentage of IRB members withan industry relationship from 2005 through 2014 (2005:37.2%; 95% CI, 32.7%-42.0%; 2014:32.1%; 95% CI, 28.0%-36.4%; P =.09). However, since 2005, the percentageof members who felt another member did not properly disclose a financial relationship decreased from 10.8% (95% CI, 8.0%-14.4%) to 6.7% (95% CI, 4.7%-9.4%) (P =.04), asdid the percentage who felt pressure from their institution or department to approve a protocol (2005:18.6%; 95% CI, 15. 0%-22.9%; 2014:10.0%; 95% CI, 7.6%-13.0%; P <.001). The percentage of members with a conflict of interest who voted on protocols with which they have a conflict has not changed, although the percentage who said they always disclose relationships increased significantly from 54.9% in 2005 (95% CI, 42.2%-66.9%) to80.0%in 2014 (95% CI, 65.3%-89.4%) (P =.01). We also found evidence of anti-industry bias in the presentation of protocols to the IRB. CONCLUSIONS AND RELEVANCE: The results show significant positive progress in the reporting and management ofconflicts of interest among IRB membersin academic health centers since 2005 after adjusting for other factors. Additional attention should be focused on deterring IRB members from inappropriately voting on or presenting protocols in a biased manner. Copyright 2015 American Medical Association. All rights reserved.

News Article | December 20, 2016

CHICAGO, Dec. 20, 2016 /PRNewswire/ -- Tribune Media Company (NYSE: TRCO) today announced that it has agreed to sell substantially all of its Digital and Data business operations, comprised of Gracenote video, music and sports, to the Nielsen Company (NYSE: NLSN) for $560 million in cash,...

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